Disrupted in Schizophrenia 1 forms pathological aggresomes that disrupt its function in intracellular transport

DISC1: Structure, Function, and Therapeutic Potential for Major Mental Illness

(2011) Dinesh C. Soares et al.   ACS Chemical Neuroscience

Convergence of Two Independent Mental Disease Genes on the Protein Level: Recruitment of Dysbindin to Cell-Invasive Disrupted-In-Schizophrenia 1 Aggresomes

(2011) Philipp Ottis et al.   BIOLOGICAL PSYCHIATRY

β-Subunits Promote the Expression of CaV2.2 Channels by Reducing Their Proteasomal Degradation

(2011) Dominic Waithe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in mice

(2011) Jie Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Co-ordinated action of DISC1, PDE4B and GSK3β in modulation of cAMP signalling

(2011) B C Carlyle et al.   MOLECULAR PSYCHIATRY

DISC1-dependent switch from progenitor proliferation to migration in the developing cortex

(2011) Koko Ishizuka et al.   NATURE

Linking neurodevelopmental and synaptic theories of mental illness through DISC1

(2011) Nicholas J. Brandon et al.   NATURE REVIEWS NEUROSCIENCE

Common DISC1 Polymorphisms Disrupt Wnt/GSK3β Signaling and Brain Development

(2011) Karun K. Singh et al.   NEURON

DISC1-binding proteins in neural development, signalling and schizophrenia

(2011) Nicholas J. Bradshaw et al.   NEUROPHARMACOLOGY

DISC1 regulates synaptic vesicle transport via a lithium-sensitive pathway

(2011) Rafael Flores et al.   NEUROSCIENCE RESEARCH

Disrupted-in-Schizophrenia 1-mediated axon guidance involves TRIO-RAC-PAK small GTPase pathway signaling

(2011) S.-Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DISCopathies: Brain Disorders Related to DISC1 Dysfunction

(2011) C. Korth   REVIEWS IN THE NEUROSCIENCES

DISC1 at 10: connecting psychiatric genetics and neuroscience

(2011) David J. Porteous et al.   TRENDS IN MOLECULAR MEDICINE

Mitochondrial trafficking and the provision of energy and calcium buffering at excitatory synapses

(2010) Andrew F. MacAskill et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The DISC1 Ser704Cys substitution affects centrosomal localization of its binding partner PCM1 in glia in human brain

(2010) S. L. Eastwood et al.   HUMAN MOLECULAR GENETICS

Disrupted in Schizophrenia-1 regulates intracellular trafficking of mitochondria in neurons

(2010) T A Atkin et al.   MOLECULAR PSYCHIATRY

Insoluble DISC1–Boymaw fusion proteins

(2010) X Zhou et al.   MOLECULAR PSYCHIATRY

The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function

(2010) Q Wang et al.   MOLECULAR PSYCHIATRY

Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

(2010) Akiko Hayashi-Takagi et al.   NATURE NEUROSCIENCE

Dixdc1 Is a Critical Regulator of DISC1 and Embryonic Cortical Development

(2010) Karun K. Singh et al.   NEURON

Delivery of GABAARs to Synapses Is Mediated by HAP1-KIF5 and Disrupted by Mutant Huntingtin

(2010) Alison E. Twelvetrees et al.   NEURON

Association of DISC1 gene with schizophrenia in families from two distinct French and Algerian populations

(2010) Aude-Marie Lepagnol-Bestel et al.   PSYCHIATRIC GENETICS

Investigation of an epistastic effect between a set of TAAR6 and HSP-70 genes variations and major mood disorders

(2009) Chi-Un Pae et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Oligomer Assembly of the C-Terminal DISC1 Domain (640−854) Is Controlled by Self-Association Motifs and Disease-Associated Polymorphism S704C

(2009) S. Rutger Leliveld et al.   BIOCHEMISTRY

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

(2009) Yingwei Mao et al.   CELL

Association of DISC1 and TSNAX genes and affective disorders in the depression case–control (DeCC) and bipolar affective case–control (BACCS) studies

(2009) A Schosser et al.   MOLECULAR PSYCHIATRY

Miro1 Is a Calcium Sensor for Glutamate Receptor-Dependent Localization of Mitochondria at Synapses

(2009) Andrew F. MacAskill et al.   NEURON

TAAR 6 and HSP-70 variations associated with bipolar disorder

(2009) Chi-Un Pae et al.   NEUROSCIENCE LETTERS

Recruitment of PCM1 to the Centrosome by the Cooperative Action of DISC1 and BBS4

(2008) Atsushi Kamiya et al.   ARCHIVES OF GENERAL PSYCHIATRY

Association analysis of heat shock protein 70 gene polymorphisms in schizophrenia

(2008) Jung Jin Kim et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Autophagy-mediated clearance of aggresomes is not a universal phenomenon

(2008) Esther S.P. Wong et al.   HUMAN MOLECULAR GENETICS

Insolubility of Disrupted-in-Schizophrenia 1 Disrupts Oligomer-Dependent Interactions with Nuclear Distribution Element 1 and Is Associated with Sporadic Mental Disease

(2008) S. R. Leliveld et al.   JOURNAL OF NEUROSCIENCE

DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder

(2008) W Hennah et al.   MOLECULAR PSYCHIATRY