Seeding Variability of Different Alpha Synuclein Strains in Synucleinopathies

Differential α-synuclein expression contributes to selective vulnerability of hippocampal neuron subpopulations to fibril-induced toxicity

(2018) Esteban Luna et al.   ACTA NEUROPATHOLOGICA

Are dementia with Lewy bodies and Parkinson’s disease dementia the same disease?

(2018) Kurt A. Jellinger et al.   BMC Medicine

Structural differences between toxic and nontoxic HypF-N oligomers

(2018) Claudia Capitini et al.   CHEMICAL COMMUNICATIONS

Molecular and Clinical Aspects of Protein Aggregation Assays in Neurodegenerative Diseases

(2018) Anna Villar-Piqué et al.   MOLECULAR NEUROBIOLOGY

Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies

(2018) Chao Peng et al.   NATURE

Potent prion-like behaviors of pathogenic α-synuclein and evaluation of inactivation methods

(2018) Airi Tarutani et al.   Acta Neuropathologica Communications

Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC

(2018) Bradley R. Groveman et al.   Acta Neuropathologica Communications

Differentiation of atypical Parkinson syndromes

(2017) Günter U. Höglinger et al.   JOURNAL OF NEURAL TRANSMISSION

Neuropathological Staging of Brain Pathology in Sporadic Parkinson’s disease: Separating the Wheat from the Chaff

(2017) Heiko Braak et al.   Journal of Parkinsons Disease

The Effect of Fragmented Pathogenic α-Synuclein Seeds on Prion-like Propagation

(2016) Airi Tarutani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Detection of Atypical H-Type Bovine Spongiform Encephalopathy and Discrimination of Bovine Prion Strains by Real-Time Quaking-Induced Conversion

(2016) Kentaro Masujin et al.   JOURNAL OF CLINICAL MICROBIOLOGY

ɑ-Synuclein strains and the variable pathologies of synucleinopathies

(2016) Wouter Peelaerts et al.   JOURNAL OF NEUROCHEMISTRY

The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases

(2016) Matthias Schmitz et al.   Nature Protocols

Prions and Protein Assemblies that Convey Biological Information in Health and Disease

(2016) David W. Sanders et al.   NEURON

Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies

(2016) Graham Fairfoul et al.   Annals of Clinical and Translational Neurology

Combined Alzheimer's disease and cerebrovascular staging explains advanced dementia cognition

(2015) María Ascensión Zea-Sevilla et al.   Alzheimers & Dementia

Surface-Enhanced Raman Scattering Spectra of Thioflavin T: Manifestation of the Electromagnetic and Molecular Enhancement Mechanisms

(2015) A. A. Maskevich et al.   Journal of Applied Spectroscopy

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

(2015) Stanley B. Prusiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Brainstem Pathologies of Parkinson's Disease and Dementia with Lewy Bodies

(2014) Kay Seidel et al.   BRAIN PATHOLOGY

Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases

(2014) Maria Cramm et al.   MOLECULAR NEUROBIOLOGY

Alpha-synuclein and tau: teammates in neurodegeneration?

(2014) Simon Moussaud et al.   Molecular Neurodegeneration

Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons

(2013) Jing L. Guo et al.   CELL

Neuronal vulnerability, pathogenesis, and Parkinson's disease

(2013) David Sulzer et al.   MOVEMENT DISORDERS

Association of prion protein genotype and scrapie prion protein type with cellular prion protein charge isoform profiles in cerebrospinal fluid of humans with sporadic or familial prion diseases

(2013) Matthias Schmitz et al.   NEUROBIOLOGY OF AGING

The Function of α-Synuclein

(2013) Jacob T. Bendor et al.   NEURON

Transmission of multiple system atrophy prions to transgenic mice

(2013) J. C. Watts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and functional characterization of two alpha-synuclein strains

(2013) Luc Bousset et al.   Nature Communications

The prion hypothesis in Parkinson's disease: Braak to the future

(2013) Naomi P Visanji et al.   Acta Neuropathologica Communications

Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion

(2011) Ryuichiro Atarashi et al.   NATURE MEDICINE

Staging/typing of Lewy body related α-synuclein pathology: a study of the BrainNet Europe Consortium

(2009) Irina Alafuzoff et al.   ACTA NEUROPATHOLOGICA

DNA induced folding/fibrillation of alpha-synuclein: new insights in Parkinson's disease

(2009) Muralidhar et al.   Frontiers in Bioscience-Landmark

Composite rating scales

(2009) Pablo Martinez-Martin   JOURNAL OF THE NEUROLOGICAL SCIENCES

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

(2008) Jia-Yi Li et al.   NATURE MEDICINE