Marine Cyanobacteria: A Source of Lead Compounds and their Clinically-Relevant Molecular Targets
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Title
Marine Cyanobacteria: A Source of Lead Compounds and their Clinically-Relevant Molecular Targets
Authors
Keywords
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Journal
MOLECULES
Volume 25, Issue 9, Pages 2197
Publisher
MDPI AG
Online
2020-05-08
DOI
10.3390/molecules25092197
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Note: Only part of the references are listed.- Tutuilamides A–C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties
- (2020) Lena Keller et al. ACS Chemical Biology
- Inhibitory effects of biseokeaniamide A against lipopolysaccharide-induced signal transduction
- (2020) Osamu Ohno et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Antibody–Drug Conjugate Payloads; Study of Auristatin Derivatives
- (2020) Michinori Akaiwa et al. CHEMICAL & PHARMACEUTICAL BULLETIN
- A Convolutional Neural Network-Based Approach for the Rapid Annotation of Molecularly Diverse Natural Products
- (2020) Raphael Reher et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Ahp-Cyclodepsipeptide Inhibitors of Elastase: Lyngbyastatin 7 Stability, Scalable Synthesis, and Focused Library Analysis
- (2020) Danmeng Luo et al. ACS Medicinal Chemistry Letters
- Novel small molecule therapeutic agents for Alzheimer disease: Focusing on BACE1 and multi-target directed ligands
- (2020) Aida Iraji et al. BIOORGANIC CHEMISTRY
- Total Synthesis and Antitrypanosomal Activity of Janadolide and Simplified Analogues
- (2020) Jonathan H. Chung et al. ORGANIC LETTERS
- Santacruzamate A Ameliorates AD-Like Pathology by Enhancing ER Stress Tolerance Through Regulating the Functions of KDELR and Mia40-ALR in vivo and in vitro
- (2019) Lei Chen et al. Frontiers in Cellular Neuroscience
- Design, synthesis, and bioactivities of tasiamide B derivatives as cathepsin D inhibitors
- (2019) Zhi Li et al. JOURNAL OF PEPTIDE SCIENCE
- Cyanobacterial peptides as a tour de force in the chemical space of antiparasitic agents
- (2019) Luis Rivas et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Falcipain Inhibitors Based on the Natural Product Gallinamide A are Potent in vitro and in vivo Antimalarials
- (2019) Alexander Stoye et al. JOURNAL OF MEDICINAL CHEMISTRY
- Natural Products from Cyanobacteria: Focus on Beneficial Activities
- (2019) Justine Demay et al. Marine Drugs
- Kyanamide, a new Ahp-containing depsipeptide from marine cyanobacterium Caldora penicillata
- (2019) Kaori Ozaki et al. TETRAHEDRON
- Histone-deacetylase inhibition sensitizes PD1 blockade-resistant B-cell lymphomas
- (2019) Xiaoguang Wang et al. Cancer Immunology Research
- The proteasome as a drug target in the metazoan pathogen, Schistosoma mansoni
- (2019) Betsaida Bibo-Verdugo et al. ACS Infectious Diseases
- 20S proteasome as a drug target in Trichomonas vaginalis
- (2019) Anthony J. O'Donoghue et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A fluorine scan on the Zn2+-binding thiolate side chain of HDAC inhibitor largazole: Synthesis, biological evaluation, and molecular modeling
- (2019) Bingbing Zhang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and Trypanosoma cruzi Cruzain
- (2019) Paul D. Boudreau et al. JOURNAL OF MEDICINAL CHEMISTRY
- Natural Compounds with Anti-BACE1 Activity as Promising Therapeutic Drugs for Treating Alzheimerʼs Disease
- (2019) Mehjabeen Naushad et al. PLANTA MEDICA
- Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module
- (2018) Meredith A. Skiba et al. ACS Chemical Biology
- Cathepsins: Proteases that are vital for survival but can also be fatal
- (2018) Seema Patel et al. BIOMEDICINE & PHARMACOTHERAPY
- Pharmacological or transcriptional inhibition of both HDAC1 and 2 leads to cell cycle blockage and apoptosis via p21Waf1/Cip1 and p19INK4d upregulation in hepatocellular carcinoma
- (2018) Hengyu Zhou et al. CELL PROLIFERATION
- Structural Diversity and Anticancer Activity of Marine-Derived Elastase Inhibitors: Key Features and Mechanisms Mediating the Antimetastatic Effects in Invasive Breast Cancer
- (2018) Fatma H. Al-Awadhi et al. CHEMBIOCHEM
- A novel Anti-Cancer Stem Cells compound optimized from the natural symplostatin 4 scaffold inhibits Wnt/β-catenin signaling pathway
- (2018) Shuangwei Liu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- ATG5 Promotes Death Signaling in Response to the Cyclic Depsipeptides Coibamide A and Apratoxin A
- (2018) Xuemei Wan et al. Marine Drugs
- Process Development and Scale-up Total Synthesis of Largazole, a Potent Class I Histone Deacetylase Inhibitor
- (2018) Qi-Yin Chen et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Development of apratoxin S10 (Apra S10) as an anti-pancreatic cancer agent and its preliminary evaluation in an orthotopic patient-derived xenograft (PDX) model
- (2018) Weijing Cai et al. INVESTIGATIONAL NEW DRUGS
- Improved Total Synthesis and Biological Evaluation of Coibamide A Analogues
- (2018) Guiyang Yao et al. JOURNAL OF MEDICINAL CHEMISTRY
- Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents
- (2018) Jehad Almaliti et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Evaluating Marine Cyanobacteria as a Source for CNS Receptor Ligands
- (2018) Andrea Rague et al. MOLECULES
- Serine protease inhibitors to treat inflammation: a patent review (2011-2016)
- (2017) Feryel Soualmia et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- HDAC10 as a potential therapeutic target in ovarian cancer
- (2017) Muhtadi M. Islam et al. GYNECOLOGIC ONCOLOGY
- Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity
- (2017) Gregory M. LaMonte et al. JOURNAL OF MEDICINAL CHEMISTRY
- Integrating Molecular Networking and Biological Assays To Target the Isolation of a Cytotoxic Cyclic Octapeptide, Samoamide A, from an American Samoan Marine Cyanobacterium
- (2017) C. Benjamin Naman et al. JOURNAL OF NATURAL PRODUCTS
- Biseokeaniamides A, B, and C, Sterol O-Acyltransferase Inhibitors from an Okeania sp. Marine Cyanobacterium
- (2017) Arihiro Iwasaki et al. JOURNAL OF NATURAL PRODUCTS
- The Face of a Molecule
- (2017) William H. Gerwick JOURNAL OF NATURAL PRODUCTS
- Marine Natural Product Honaucin A Attenuates Inflammation by Activating the Nrf2-ARE Pathway
- (2017) Samantha J. Mascuch et al. JOURNAL OF NATURAL PRODUCTS
- Grassystatins D–F, Potent Aspartic Protease Inhibitors from Marine Cyanobacteria as Potential Antimetastatic Agents Targeting Invasive Breast Cancer
- (2017) Fatma H. Al-Awadhi et al. JOURNAL OF NATURAL PRODUCTS
- Cyanobacterial peptides as a prototype for the design of cathepsin D inhibitors
- (2017) Hao Xu et al. JOURNAL OF PEPTIDE SCIENCE
- Current Status of Marine-Derived Compounds as Warheads in Anti-Tumor Drug Candidates
- (2017) David Newman et al. Marine Drugs
- A Review Study on Macrolides Isolated from Cyanobacteria
- (2017) Mengchuan Wang et al. Marine Drugs
- Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review
- (2017) Sayed Shah et al. Marine Drugs
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- (2017) Yue Mi et al. Marine Drugs
- Genome-wide dose-dependent inhibition of histone deacetylases studies reveal their roles in enhancer remodeling and suppression of oncogenic super-enhancers
- (2017) Gilson J Sanchez et al. NUCLEIC ACIDS RESEARCH
- Synthesis, SAR and biological studies of sugar amino acid-based almiramide analogues: N-methylation leads the way
- (2017) Dipendu Das et al. ORGANIC & BIOMOLECULAR CHEMISTRY
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- (2017) Weijing Cai et al. ACS Medicinal Chemistry Letters
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- (2017) Brice J. Albert et al. Scientific Reports
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- Synthesis and biological evaluation of santacruzamate A analogues for anti-proliferative and immunomodulatory activity
- (2016) Samantha M. Gromek et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Tasiamide F, a potent inhibitor of cathepsins D and E from a marine cyanobacterium
- (2016) Fatma H. Al-Awadhi et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Antibody-drug conjugates—an emerging class of cancer treatment
- (2016) Nikolaos Diamantis et al. BRITISH JOURNAL OF CANCER
- Naturally Inspired Peptide Leads: Alanine Scanning Reveals an Actin-Targeting Thiazole Analogue of Bisebromoamide
- (2016) Heather J. Johnston et al. CHEMBIOCHEM
- Largazole Analogues Embodying Radical Changes in the Depsipeptide Ring: Development of a More Selective and Highly Potent Analogue
- (2016) Jehad Almaliti et al. JOURNAL OF MEDICINAL CHEMISTRY
- Janadolide, a Cyclic Polyketide–Peptide Hybrid Possessing a tert-Butyl Group from an Okeania sp. Marine Cyanobacterium
- (2016) Hidetoshi Ogawa et al. JOURNAL OF NATURAL PRODUCTS
- Apratoxin A Shows Novel Pancreas-Targeting Activity through the Binding of Sec 61
- (2016) Kuan-Chun Huang et al. MOLECULAR CANCER THERAPEUTICS
- Structure Determinants of Lagunamide A for Anticancer Activity and Its Molecular Mechanism of Mitochondrial Apoptosis
- (2016) Xiaoxing Huang et al. MOLECULAR PHARMACEUTICS
- Unique marine derived cyanobacterial biosynthetic genes for chemical diversity
- (2016) Karin Kleigrewe et al. NATURAL PRODUCT REPORTS
- Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole
- (2015) Dane J. Clausen et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Design, synthesis and biological evaluation of tasiamide B derivatives as BACE1 inhibitors
- (2015) Jian Liu et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and biological evaluation of the [d-MeAla11]-epimer of coibamide A
- (2015) Ryota Nabika et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Bromo-honaucin A inhibits osteoclastogenic differentiation in RAW 264.7 cells via Akt and ERK signaling pathways
- (2015) Mahesh Sapkota et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Coibamide A, a natural lariat depsipeptide, inhibits VEGFA/VEGFR2 expression and suppresses tumor growth in glioblastoma xenografts
- (2015) Jeffrey D. Serrill et al. INVESTIGATIONAL NEW DRUGS
- Integrating mass spectrometry and genomics for cyanobacterial metabolite discovery
- (2015) Nathan A. Moss et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria
- (2015) Karin Kleigrewe et al. JOURNAL OF NATURAL PRODUCTS
- Total Synthesis of the Potent Marine-Derived Elastase Inhibitor Lyngbyastatin 7 and in Vitro Biological Evaluation in Model Systems for Pulmonary Diseases
- (2015) Danmeng Luo et al. JOURNAL OF ORGANIC CHEMISTRY
- Efficient Synthesis and Stereochemical Revision of Coibamide A
- (2015) Guiyang Yao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Recent Advances in the Development of New Auristatins: Structural Modifications and Application in Antibody Drug Conjugates
- (2015) Andreas Maderna et al. MOLECULAR PHARMACEUTICS
- Biological targets and mechanisms of action of natural products from marine cyanobacteria
- (2015) Lilibeth A. Salvador-Reyes et al. NATURAL PRODUCT REPORTS
- Targeting HER3 by interfering with its Sec61-mediated cotranslational insertion into the endoplasmic reticulum
- (2015) A Ruiz-Saenz et al. ONCOGENE
- Anti-infective Natural Products from Cyanobacteria
- (2015) Timo Niedermeyer PLANTA MEDICA
- Expanding the Described Metabolome of the Marine Cyanobacterium Moorea producens JHB through Orthogonal Natural Products Workflows
- (2015) Paul D. Boudreau et al. PLoS One
- Enzyme Inhibition by Hydroamination: Design and Mechanism of a Hybrid Carmaphycin-Syringolin Enone Proteasome Inhibitor
- (2014) Daniela B.B. Trivella et al. CHEMISTRY & BIOLOGY
- Largazole, an inhibitor of class I histone deacetylases, attenuates inflammatory corneal neovascularization
- (2014) Hongyan Zhou et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Improved Total Synthesis and Biological Evaluation of Potent Apratoxin S4 Based Anticancer Agents with Differential Stability and Further Enhanced Activity
- (2014) Qi-Yin Chen et al. JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis of Gallinamide A Analogues as Potent Falcipain Inhibitors and Antimalarials
- (2014) Trent Conroy et al. JOURNAL OF MEDICINAL CHEMISTRY
- Methyl-methoxylpyrrolinone and flavinium nucleus binding signatures on falcipain-2 active site
- (2014) Olaposi I. Omotuyi JOURNAL OF MOLECULAR MODELING
- Mooreamide A: A Cannabinomimetic Lipid from the Marine Cyanobacterium Moorea bouillonii
- (2014) Emily Mevers et al. LIPIDS
- Marine-Sourced Anti-Cancer and Cancer Pain Control Agents in Clinical and Late Preclinical Development
- (2014) David Newman et al. Marine Drugs
- Potent and Orally Efficacious Bisthiazole-Based Histone Deacetylase Inhibitors
- (2014) Fei Chen et al. ACS Medicinal Chemistry Letters
- Pharmaceutical agents from filamentous marine cyanobacteria
- (2013) Lik Tong Tan DRUG DISCOVERY TODAY
- Potent Elastase Inhibitors from Cyanobacteria: Structural Basis and Mechanisms Mediating Cytoprotective and Anti-Inflammatory Effects in Bronchial Epithelial Cells
- (2013) Lilibeth A. Salvador et al. JOURNAL OF MEDICINAL CHEMISTRY
- Examination of the Mode of Action of the Almiramide Family of Natural Products against the Kinetoplastid Parasite Trypanosoma brucei
- (2013) Laura M. Sanchez et al. JOURNAL OF NATURAL PRODUCTS
- Santacruzamate A, a Potent and Selective Histone Deacetylase Inhibitor from the Panamanian Marine Cyanobacterium cf. Symploca sp.
- (2013) Christopher M. Pavlik et al. JOURNAL OF NATURAL PRODUCTS
- Coibamide A Induces mTOR-Independent Autophagy and Cell Death in Human Glioblastoma Cells
- (2013) Andrew M. Hau et al. PLoS One
- Largazole, a class I histone deacetylase inhibitor, enhances TNF-α-induced ICAM-1 and VCAM-1 expression in rheumatoid arthritis synovial fibroblasts
- (2013) Salahuddin Ahmed et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Largazole Arrests Cell Cycle at G1 Phase and Triggers Proteasomal Degradation of E2F1 in Lung Cancer Cells
- (2013) Li-Chuan Wu et al. ACS Medicinal Chemistry Letters
- Total synthesis of grassystatin A, a probe for cathepsin E function
- (2012) Siming Yang et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Marine Cyanobacterial Fatty Acid Amides Acting on Cannabinoid Receptors
- (2012) Rana Montaser et al. CHEMBIOCHEM
- The Carmaphycins: New Proteasome Inhibitors Exhibiting an α,β-Epoxyketone Warhead from a Marine Cyanobacterium
- (2012) Alban R. Pereira et al. CHEMBIOCHEM
- The Antimalarial Natural Product Symplostatin 4 Is a Nanomolar Inhibitor of the Food Vacuole Falcipains
- (2012) Sara Christina Stolze et al. CHEMISTRY & BIOLOGY
- Honaucins A−C, Potent Inhibitors of Inflammation and Bacterial Quorum Sensing: Synthetic Derivatives and Structure-Activity Relationships
- (2012) Hyukjae Choi et al. CHEMISTRY & BIOLOGY
- Falcipain inhibitors as potential therapeutics for resistant strains of malaria: a patent review
- (2012) Uttam Rajaram Mane et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Cyanobacterial Peptides as a Prototype for the Design of Potent β-Secretase Inhibitors and the Development of Selective Chemical Probes for Other Aspartic Proteases
- (2012) Yanxia Liu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Symplocin A, a Linear Peptide from the Bahamian Cyanobacterium Symploca sp. Configurational Analysis of N,N-Dimethylamino Acids by Chiral-Phase HPLC of Naphthacyl Esters
- (2012) Tadeusz F. Molinski et al. JOURNAL OF NATURAL PRODUCTS
- A histone deacetylase inhibitor, largazole, decreases liver fibrosis and angiogenesis by inhibiting transforming growth factor-β and vascular endothelial growth factor signalling
- (2012) Yuqing Liu et al. LIVER INTERNATIONAL
- Marine Cyanobacteria Compounds with Anticancer Properties: A Review on the Implication of Apoptosis
- (2012) Margarida Costa et al. Marine Drugs
- The chemical ecology of cyanobacteria
- (2012) Pedro N. Leão et al. NATURAL PRODUCT REPORTS
- Largazole: From discovery to broad-spectrum therapy
- (2012) Jiyong Hong et al. NATURAL PRODUCT REPORTS
- Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms
- (2012) M E Law et al. ONCOGENE
- Largazole and Its Derivatives Selectively Inhibit Ubiquitin Activating Enzyme (E1)
- (2012) Dana Ungermannova et al. PLoS One
- Mass spectral molecular networking of living microbial colonies
- (2012) J. Watrous et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Histone deacetylase inhibitors are potent inducers of gene expression in latent EBV and sensitize lymphoma cells to nucleoside antiviral agents
- (2011) S. K. Ghosh et al. BLOOD
- Total Synthesis, Stereochemical Assignment, and Antimalarial Activity of Gallinamide A
- (2011) Trent Conroy et al. CHEMISTRY-A EUROPEAN JOURNAL
- Looking at the proteases from a simple perspective
- (2011) Helena C. Castro et al. JOURNAL OF MOLECULAR RECOGNITION
- Cannabinomimetic Lipid from a Marine Cyanobacterium
- (2011) Marcelino Gutiérrez et al. JOURNAL OF NATURAL PRODUCTS
- Synthetic Routes and Biological Evaluation of Largazole and Its Analogues as Potent Histone Deacetylase Inhibitors
- (2011) Shang Li et al. MOLECULES
- Single Cell Genome Amplification Accelerates Identification of the Apratoxin Biosynthetic Pathway from a Complex Microbial Assemblage
- (2011) Rashel V. Grindberg et al. PLoS One
- Systematic Chemical Mutagenesis Identifies a Potent Novel Apratoxin A/E Hybrid with Improved in Vivo Antitumor Activity
- (2011) Qi-Yin Chen et al. ACS Medicinal Chemistry Letters
- In Vitro and In Vivo Osteogenic Activity of Largazole
- (2011) Su-Ui Lee et al. ACS Medicinal Chemistry Letters
- Biologically active secondary metabolites from marine cyanobacteria
- (2010) Joshawna K Nunnery et al. CURRENT OPINION IN BIOTECHNOLOGY
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- (2010) Lik Tong Tan JOURNAL OF APPLIED PHYCOLOGY
- Almiramides A−C: Discovery and Development of a New Class of Leishmaniasis Lead Compounds
- (2010) Laura M. Sanchez et al. JOURNAL OF MEDICINAL CHEMISTRY
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- (2010) Ashootosh Tripathi et al. JOURNAL OF NATURAL PRODUCTS
- Total synthesis and stereochemical reassignment of tasiamide B
- (2010) Tiantian Sun et al. JOURNAL OF PEPTIDE SCIENCE
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- (2010) Susan Matthew et al. Marine Drugs
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- (2010) Trent Conroy et al. ORGANIC LETTERS
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- (2010) Brent K. Rubio et al. TETRAHEDRON LETTERS
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- (2009) Kanchan Taori et al. CHEMBIOCHEM
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- (2009) Shensi Shen et al. JOURNAL OF CELL BIOLOGY
- Grassystatins A−C from Marine Cyanobacteria, Potent Cathepsin E Inhibitors That Reduce Antigen Presentation
- (2009) Jason C. Kwan et al. JOURNAL OF MEDICINAL CHEMISTRY
- Antimalarial Peptides from Marine Cyanobacteria: Isolation and Structural Elucidation of Gallinamide A
- (2009) Roger G. Linington et al. JOURNAL OF NATURAL PRODUCTS
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- (2009) Sarath P. Gunasekera et al. JOURNAL OF NATURAL PRODUCTS
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- (2009) Jason Kwan et al. Marine Drugs
- Apratoxin A Reversibly Inhibits the Secretory Pathway by Preventing Cotranslational Translocation
- (2009) Y. Liu et al. MOLECULAR PHARMACOLOGY
- Synthesis and Histone Deacetylase Inhibitory Activity of Largazole Analogs: Alteration of the Zinc-Binding Domain and Macrocyclic Scaffold
- (2009) Albert A. Bowers et al. ORGANIC LETTERS
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- (2009) Toshiaki Teruya et al. ORGANIC LETTERS
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- (2009) Susan Matthew et al. PLANTA MEDICA
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- (2009) M. A. Rivieccio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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