Falcipain inhibitors as potential therapeutics for resistant strains of malaria: a patent review

Falcipain Inhibition as a Promising Antimalarial Target

(2012) Maria Marco et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Design and synthesis of small molecular dual inhibitor of falcipain-2 and dihydrofolate reductase as antimalarial agent

(2011) Huang Huang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and Antimalarial Activity of Novel Dihydro-Artemisinin Derivatives

(2011) Yang Liu et al.   MOLECULES

Comparison of the antiplasmodial and falcipain-2 inhibitory activity of β-amino alcohol thiolactone-chalcone and isatin-chalcone hybrids

(2010) Renate H. Hans et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of novel peptidomimetics as inhibitors of protozoan cysteine proteases falcipain-2 and rhodesain

(2010) Roberta Ettari et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Falcipain Inhibitors: Optimization Studies of the 2-Pyrimidinecarbonitrile Lead Series†

(2010) Jose M. Coterón et al.   JOURNAL OF MEDICINAL CHEMISTRY

Endoperoxide Carbonyl Falcipain 2/3 Inhibitor Hybrids: Toward Combination Chemotherapy of Malaria through a Single Chemical Entity

(2010) Peter Gibbons et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel 2H-isoquinolin-3-ones as antiplasmodial falcipain-2 inhibitors

(2009) Nicola Micale et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Artemisinin-dipeptidyl vinyl sulfone hybrid molecules: Design, synthesis and preliminary SAR for antiplasmodial activity and falcipain-2 inhibition

(2009) Rita Capela et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Antimalarial activity of azadipeptide nitriles

(2009) Reik Löser et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Antimalarial pharmacodynamics of chalcone derivatives in combination with artemisinin against Plasmodium falciparum in vitro

(2009) Amit Bhattacharya et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Identification of Novel Falcipain-2 Inhibitors as Potential Antimalarial Agents through Structure-Based Virtual Screening

(2009) Honglin Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

2-(3,4-Dihydro-4-Oxothieno[2,3-d]pyrimidin-2-ylthio) Acetamides as a New Class of Falcipain-2 Inhibitors. 3. Design, Synthesis and Biological Evaluation

(2009) Jin Zhu et al.   MOLECULES

2-Amido-3-(1H-Indol-3-yl)-N-Substitued-Propanamides as a New Class of Falcipain-2 Inhibitors. 1. Design, Synthesis, Biological Evaluation and Binding Model Studies

(2009) Jin Zhu et al.   MOLECULES

A Prodomain Peptide ofPlasmodium falciparumCysteine Protease (Falcipain-2) Inhibits Malaria Parasite Development

(2008) Reshma Korde et al.   JOURNAL OF MEDICINAL CHEMISTRY