Novel small molecule therapeutic agents for Alzheimer disease: Focusing on BACE1 and multi-target directed ligands

Published 2020 View Full Article

Authors

Keywords

Alzheimer’s Disease, Amyloidogenic pathway, Structure-activity relationship, α-secretase inducers, γ-secretase inhibitors, BACE1 inhibitors, Multi target-directed ligand, Small molecule inhibitors, PDE4D, 5-HT, Natural products, Virtual screening

Journal

BIOORGANIC CHEMISTRY

Volume 97, Issue -, Pages 103649

Publisher

Elsevier BV

Online

2020-02-23

DOI

10.1016/j.bioorg.2020.103649

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