Lipase Treatment of Dietary Krill Oil, but Not Fish Oil, Enables Enrichment of Brain Eicosapentaenoic Acid and Docosahexaenoic Acid

Enrichment of brain docosahexaenoic acid (DHA) is highly dependent upon the molecular carrier of dietary DHA: Lysophosphatidylcholine is more efficient than either phosphatidylcholine or triacylglycerol

(2019) Dhavamani Sugasini et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Docosahexaenoic acid modulates brain-derived neurotrophic factor via GPR40 in the brain and alleviates diabesity-associated learning and memory deficits in mice

(2018) Chandan Sona et al.   NEUROBIOLOGY OF DISEASE

Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation

(2018) Bruno Lima Giacobbo et al.   MOLECULAR NEUROBIOLOGY

Dietary lysophosphatidylcholine-EPA enriches both EPA and DHA in the brain: Potential treatment for depression

(2018) Poorna ChandraRao Yalagala et al.   JOURNAL OF LIPID RESEARCH

Rate of acyl migration in lysophosphatidylcholine (LPC) is dependent upon the nature of the acyl group. Greater stability of sn-2 docosahexaenoyl LPC compared to the more saturated LPC species

(2017) Dhavamani Sugasini et al.   PLoS One

Docosahexaenoic acid (DHA): An essential nutrient and a nutraceutical for brain health and diseases

(2017) Grace Y. Sun et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Dietary docosahexaenoic acid (DHA) as lysophosphatidylcholine, but not as free acid, enriches brain DHA and improves memory in adult mice

(2017) Dhavamani Sugasini et al.   Scientific Reports

Enhanced incorporation of dietary DHA into lymph phospholipids by altering its molecular carrier

(2016) Papasani V. Subbaiah et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The role of omega-3 polyunsaturated fatty acids eicosapentaenoic and docosahexaenoic acids in the treatment of major depression and Alzheimer's disease: Acting separately or synergistically?

(2016) Cai Song et al.   PROGRESS IN LIPID RESEARCH

No Effect of Omega-3 Fatty Acid Supplementation on Cognition and Mood in Individuals with Cognitive Impairment and Probable Alzheimer’s Disease: A Randomised Controlled Trial

(2015) Michelle Phillips et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ethyl-eicosapentaenoic acid treatment in Huntington's disease: A placebo-controlled clinical trial

(2015) Joaquim J. Ferreira et al.   MOVEMENT DISORDERS

β-oxidation and rapid metabolism, but not uptake regulate brain eicosapentaenoic acid levels

(2015) Chuck T. Chen et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Influence of feeding graded levels of canned sardines on the inflammatory markers and tissue fatty acid composition of Wistar rats

(2014) Pedro O. Rodrigues et al.   BRITISH JOURNAL OF NUTRITION

Docosahexaenoic acid confers enduring neuroprotection in experimental stroke

(2014) Sung-Ha Hong et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

A reexamination of krill oil bioavailability studies

(2014) Norman Salem et al.   Lipids in Health and Disease

Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid

(2014) Long N. Nguyen et al.   NATURE

ω-3 Fatty Acid Supplementation as a Potential Therapeutic Aid for the Recovery from Mild Traumatic Brain Injury/Concussion

(2014) Erin Cernkovich Barrett et al.   Advances in Nutrition

EPA but Not DHA Appears To Be Responsible for the Efficacy of Omega-3 Long Chain Polyunsaturated Fatty Acid Supplementation in Depression: Evidence from a Meta-Analysis of Randomized Controlled Trials

(2013) Julian G Martins   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Enhanced increase of omega-3 index in healthy individuals with response to 4-week n-3 fatty acid supplementation from krill oil versus fish oil

(2013) Vanu R Ramprasath et al.   Lipids in Health and Disease

Prescription n-3 Fatty Acids, But Not Eicosapentaenoic Acid Alone, Improve Reference Memory-Related Learning Ability by Increasing Brain-Derived Neurotrophic Factor Levels in SHR.Cg-Lepr cp /NDmcr rats, A Metabolic Syndrome Model

(2013) Michio Hashimoto et al.   NEUROCHEMICAL RESEARCH

Docosahexaenoic acid homeostasis, brain aging and Alzheimer's disease: Can we reconcile the evidence?

(2012) Stephen C. Cunnane et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Benefits of Structured and Free Monoacylglycerols to Deliver Eicosapentaenoic (EPA) in a Model of Lipid Malabsorption

(2012) Cristina Cruz-Hernandez et al.   Nutrients

Docosahexaenoic Acid Signalolipidomics in Nutrition: Significance in Aging, Neuroinflammation, Macular Degeneration, Alzheimer's, and Other Neurodegenerative Diseases

(2011) Nicolas G. Bazan et al.   Annual Review of Nutrition

Effect of Dietary n-3 Polyunsaturated Fatty Acids on Brain Lipid Fatty Acid Composition, Learning Ability, and Memory of Senescence-Accelerated Mouse

(2011) A. L. Petursdottir et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Different sources of omega-3 polyunsaturated fatty acids affects apparent digestibility, tissue deposition, and tissue oxidative stability in growing female rats

(2011) Janet C Tou et al.   Lipids in Health and Disease

Incorporation of EPA and DHA into plasma phospholipids in response to different omega-3 fatty acid formulations - a comparative bioavailability study of fish oil vs. krill oil

(2011) Jan Schuchardt et al.   Lipids in Health and Disease

DHA Improves Cognition and Prevents Dysfunction of Entorhinal Cortex Neurons in 3xTg-AD Mice

(2011) Dany Arsenault et al.   PLoS One

Docosahexaenoic Acid Supplementation and Cognitive Decline in Alzheimer Disease

(2010) Joseph F. Quinn et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Polyunsaturated fatty acids deficits are associated with psychotic state and negative symptoms in patients with schizophrenia

(2010) M.M. Sethom et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Short-term docosapentaenoic acid (22 : 5 n-3) supplementation increases tissue docosapentaenoic acid, DHA and EPA concentrations in rats

(2009) Gunveen Kaur et al.   BRITISH JOURNAL OF NUTRITION

DHA diet reduces AD pathology in young APPswe/PS1ΔE9 transgenic mice: Possible gender effects

(2009) Sylvia E. Perez et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The effects of omega-3 fatty acids monotherapy in Alzheimer's disease and mild cognitive impairment: A preliminary randomized double-blind placebo-controlled study

(2008) Chih-Chiang Chiu et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY