- Home
- Publications
- Publication Search
- Publication Details
Title
T‐cell receptor affinity in the age of cancer immunotherapy
Authors
Keywords
-
Journal
MOLECULAR CARCINOGENESIS
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-05-09
DOI
10.1002/mc.23212
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- T cell receptor and cytokine signal integration in CD8+ T cells is mediated by the protein Themis
- (2020) Joanna Brzostek et al. NATURE IMMUNOLOGY
- Prediction of cancer neoepitopes needs new rules
- (2020) Cory A. Brennick et al. SEMINARS IN IMMUNOLOGY
- Turning the corner on therapeutic cancer vaccines
- (2019) Robert E. Hollingsworth et al. npj Vaccines
- T cell antigen discovery via signaling and antigen-presenting bifunctional receptors
- (2019) Alok V. Joglekar et al. NATURE METHODS
- Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy
- (2019) Nadia Mensali et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Quantitative Prediction of the Landscape of T Cell Epitope Immunogenicity in Sequence Space
- (2019) Masato Ogishi et al. Frontiers in Immunology
- Machine Learning for Cancer Immunotherapies Based on Epitope Recognition by T Cell Receptors
- (2019) Anja Mösch et al. Frontiers in Genetics
- Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes
- (2018) Marvin H. Gee et al. CELL
- Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro
- (2018) Marvin H. Gee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding
- (2018) Leah V. Sibener et al. CELL
- Improving T Cell Receptor On-Target Specificity via Structure-Guided Design
- (2018) Lance M. Hellman et al. MOLECULAR THERAPY
- Altered Binding of Tumor Antigenic Peptides to MHC Class I Affects CD8+ T Cell–Effector Responses
- (2018) Eleanor Clancy-Thompson et al. Cancer Immunology Research
- Leveraging TCR Affinity in Adoptive Immunotherapy against Shared Tumor/Self-Antigens
- (2018) Aaron M. Miller et al. Cancer Immunology Research
- Transcription Factor IRF4 Promotes CD8 + T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection
- (2017) Kevin Man et al. IMMUNITY
- Subtle changes at the variable domain interface of the T-cell receptor can strongly increase affinity
- (2017) Preeti Sharma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Generation of higher affinity T cell receptors by antigen-driven differentiation of progenitor T cells in vitro
- (2017) Thomas M Schmitt et al. NATURE BIOTECHNOLOGY
- VDJdb: a curated database of T-cell receptor sequences with known antigen specificity
- (2017) Mikhail Shugay et al. NUCLEIC ACIDS RESEARCH
- ATLAS: A database linking binding affinities with structures for wild-type and mutant TCR-pMHC complexes
- (2017) Tyler Borrman et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Normalized Synergy Predicts That CD8 Co-Receptor Contribution to T Cell Receptor (TCR) and pMHC Binding Decreases As TCR Affinity Increases in Human Viral-Specific T Cells
- (2017) Chad M. Williams et al. Frontiers in Immunology
- Fine-Tuning of Optimal TCR Signaling in Tumor-Redirected CD8 T Cells by Distinct TCR Affinity-Mediated Mechanisms
- (2017) Danilo Presotto et al. Frontiers in Immunology
- Deep Mutational Scans as a Guide to Engineering High Affinity T Cell Receptor Interactions with Peptide-bound Major Histocompatibility Complex
- (2016) Daniel T. Harris et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- High antigen levels induce an exhausted phenotype in a chronic infection without impairing T cell expansion and survival
- (2016) Daniel T. Utzschneider et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Low-Affinity Memory CD8+T Cells Mediate Robust Heterologous Immunity
- (2016) Scott M. Krummey et al. JOURNAL OF IMMUNOLOGY
- Identification of shared TCR sequences from T cells in human breast cancer using emulsion RT-PCR
- (2016) Daniel J. Munson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neuraminidase-1: A novel therapeutic target in multistage tumorigenesis
- (2016) Fiona Haxho et al. Oncotarget
- Generation of CD8+T cells expressing two additional T-cell receptors (TETARs) for personalised melanoma therapy
- (2015) Sandra Höfflin et al. CANCER BIOLOGY & THERAPY
- TCR affinity for p/MHC formed by tumor antigens that are self-proteins: impact on efficacy and toxicity
- (2015) Jennifer D Stone et al. CURRENT OPINION IN IMMUNOLOGY
- T-cell receptors: Tugging on the anchor for a tighter hold on the tumor-associated peptide
- (2015) Julian Dyson EUROPEAN JOURNAL OF IMMUNOLOGY
- Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens
- (2015) Michael Hebeisen et al. Frontiers in Immunology
- Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response
- (2015) Ryan J. Martinez et al. Frontiers in Immunology
- Co-potentiation of antigen recognition: A mechanism to boost weak T cell responses and provide immunotherapy in vivo
- (2015) M. M. Hoffmann et al. Science Advances
- Magnetic Field-Induced T Cell Receptor Clustering by Nanoparticles Enhances T Cell Activation and Stimulates Antitumor Activity
- (2014) Karlo Perica et al. ACS Nano
- Accumulation of Dynamic Catch Bonds between TCR and Agonist Peptide-MHC Triggers T Cell Signaling
- (2014) Baoyu Liu et al. CELL
- A THEMIS:SHP1 complex promotes T-cell survival
- (2014) W. Paster et al. EMBO JOURNAL
- Structural basis for ineffective T-cell responses to MHC anchor residue-improved “heteroclitic” peptides
- (2014) Florian Madura et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- A Role for CD8 in the Developmental Tuning of Antigen Recognition and CD3 Conformational Change
- (2014) D. Gil et al. JOURNAL OF IMMUNOLOGY
- Enhancement of T Cell Responses as a Result of Synergy between Lower Doses of Radiation and T Cell Stimulation
- (2014) L. K. Spary et al. JOURNAL OF IMMUNOLOGY
- Specific Increase in Potency via Structure-Based Design of a TCR
- (2014) Karolina Malecek et al. JOURNAL OF IMMUNOLOGY
- The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals
- (2014) Robert J Salmond et al. NATURE IMMUNOLOGY
- The TCR's sensitivity to self peptide–MHC dictates the ability of naive CD8+ T cells to respond to foreign antigens
- (2014) Ross B Fulton et al. NATURE IMMUNOLOGY
- Optimal T-cell receptor affinity for inducing autoimmunity
- (2014) Sabrina Koehli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A sharp T-cell antigen receptor signaling threshold for T-cell proliferation
- (2014) B. B. Au-Yeung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Computational Design of the Affinity and Specificity of a Therapeutic T Cell Receptor
- (2014) Brian G. Pierce et al. PLoS Computational Biology
- Breaking through the central tolerance ceiling to unleash anticancer immune responses
- (2014) Maureen A Su et al. OncoImmunology
- Genome-wide structural modelling of TCR-pMHC interactions
- (2013) I-Hsin Liu et al. BMC GENOMICS
- Relapse or Eradication of Cancer Is Predicted by Peptide-Major Histocompatibility Complex Affinity
- (2013) Boris Engels et al. CANCER CELL
- 2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system
- (2013) Baoyu Liu et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Improving Antigenic Peptide Vaccines for Cancer Immunotherapy Using a Dominant Tumor-specific T Cell Receptor
- (2013) Jonathan D. Buhrman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cutting Edge: The Signals for the Generation of T Cell Memory Are Qualitatively Different Depending on TCR Ligand Strength
- (2013) K. M. Knudson et al. JOURNAL OF IMMUNOLOGY
- Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene Therapy
- (2013) Richard A. Morgan et al. JOURNAL OF IMMUNOTHERAPY
- The transcription factor IRF4 is essential for TCR affinity–mediated metabolic programming and clonal expansion of T cells
- (2013) Kevin Man et al. NATURE IMMUNOLOGY
- T-cell receptor affinity and avidity defines antitumor response and autoimmunity in T-cell immunotherapy
- (2013) S. Zhong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transnuclear TRP1-Specific CD8 T Cells with High or Low Affinity TCRs Show Equivalent Antitumor Activity
- (2013) S. K. Dougan et al. Cancer Immunology Research
- The Many Faces of Aire in Central Tolerance
- (2013) Martti Laan et al. Frontiers in Immunology
- Functional Avidity: A Measure to Predict the Efficacy of Effector T Cells?
- (2012) Selena Viganò et al. Clinical & Developmental Immunology
- Insights fromin situanalysis of TCR-pMHC recognition: response of an interaction network
- (2012) Cheng Zhu et al. IMMUNOLOGICAL REVIEWS
- Monoclonal TCR-redirected tumor cell killing
- (2012) Nathaniel Liddy et al. NATURE MEDICINE
- Trafficking of High Avidity HER-2/neu-Specific T Cells into HER-2/neu-Expressing Tumors after Depletion of Effector/Memory-Like Regulatory T Cells
- (2012) Vivian L. Weiss et al. PLoS One
- Functional differences between low- and high-affinity CD8+T cells in the tumor environment
- (2012) Rinke Bos et al. OncoImmunology
- MPID-T2: a database for sequence–structure–function analyses of pMHC and TR/pMHC structures
- (2011) Javed Mohammed Khan et al. BIOINFORMATICS
- T cell receptor signal strength in Tregand iNKT cell development demonstrated by a novel fluorescent reporter mouse
- (2011) Amy E. Moran et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Strength of TCR-Peptide/MHC Interactions and In Vivo T Cell Responses
- (2011) E. Corse et al. JOURNAL OF IMMUNOLOGY
- PAComplex: a web server to infer peptide antigen families and binding models from TCR–pMHC complexes
- (2011) I-Hsin Liu et al. NUCLEIC ACIDS RESEARCH
- Combinations of Affinity-Enhancing Mutations in a T Cell Receptor Reveal Highly Nonadditive Effects within and between Complementarity Determining Regions and Chains
- (2010) Brian G. Pierce et al. BIOCHEMISTRY
- Evidence for a TCR Affinity Threshold Delimiting Maximal CD8 T Cell Function
- (2010) D. A. Schmid et al. JOURNAL OF IMMUNOLOGY
- Peptide vaccines prevent tumor growth by activating T cells that respond to native tumor antigens
- (2010) K. R. Jordan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Attenuated T Cell Responses to a High-Potency Ligand In Vivo
- (2010) Emily Corse et al. PLOS BIOLOGY
- The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research
- (2009) M. A. Cheever et al. CLINICAL CANCER RESEARCH
- The duration of TCR/pMHC interactions regulates CTL effector function and tumor-killing capacity
- (2009) Erick Riquelme et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Increasing functional avidity of TCR-redirected T cells by removing definedN-glycosylation sites in the TCR constant domain
- (2009) Jürgen Kuball et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final analysis of a double-blind, randomised study in young women
- (2009) J Paavonen et al. LANCET
- Complete but curtailed T-cell response to very low-affinity antigen
- (2009) Dietmar Zehn et al. NATURE
- T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity
- (2008) Jennifer D. Stone et al. IMMUNOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started