Transcription Factor IRF4 Promotes CD8 + T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection

Published 2017 View Full Article

Authors

Keywords

chronic infection, exhaustion, transcription, CD8, differentiation, metabolic function, memory, IRF4, BATF, NFAT, TCF1, NFAT_AP-1_IRF4 composite element, NAICE

Journal

IMMUNITY

Volume 47, Issue 6, Pages 1129-1141.e5

Publisher

Elsevier BV

Online

2017-12-13

DOI

10.1016/j.immuni.2017.11.021

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