Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage

CSB6B prevents β-amyloid-associated neuroinflammation and cognitive impairments via inhibiting NF-κB and NLRP3 in microglia cells

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The NLRP3 inflammasome in traumatic brain injury: potential as a biomarker and therapeutic target

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Gut–Liver Axis and Inflammasome Activation in Cholangiocyte Pathophysiology

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N-myristoyltransferase deficiency impairs activation of kinase AMPK and promotes synovial tissue inflammation

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MSC exosomes alleviate temporomandibular joint osteoarthritis by attenuating inflammation and restoring matrix homeostasis

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Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production

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Improvement of fiber connectivity and functional recovery after stroke by montelukast, an available and safe anti-asthmatic drug

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Sterile Lung Inflammation Induced by Silica Exacerbates Mycobacterium tuberculosis Infection via STING-Dependent Type 2 Immunity

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Neurobehavioral Deficits After Subarachnoid Hemorrhage in Mice: Sensitivity Analysis and Development of a New Composite Score

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Microglial TREM-1 receptor mediates neuroinflammatory injury via interaction with SYK in experimental ischemic stroke

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rt269I Type of Hepatitis B Virus (HBV) Leads to HBV e Antigen Negative Infections and Liver Disease Progression via Mitochondrial Stress Mediated Type I Interferon Production in Chronic Patients With Genotype C Infections

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STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3

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Neurological Enhancement Effects of Melatonin against Brain Injury-Induced Oxidative Stress, Neuroinflammation, and Neurodegeneration via AMPK/CREB Signaling

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Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s disease progression

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Cyclic GMP–AMP signalling protects bacteria against viral infection

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Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation

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Activation of Melanocortin 1 Receptor Attenuates Early Brain Injury in a Rat Model of Subarachnoid Hemorrhage viathe Suppression of Neuroinflammation through AMPK/TBK1/NF-κB Pathway in Rats

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Functional Characterization of Duck STING in IFN-β Induction and Anti-H9N2 Avian Influenza Viruses Infections

(2019) Yuqiang Cheng et al.   Frontiers in Immunology

Pharmacological hypothermia induced neurovascular protection after severe stroke of transient middle cerebral artery occlusion in mice

(2019) Yingying Zhao et al.   EXPERIMENTAL NEUROLOGY

Serum Amyloid A-Mediated Inflammasome Activation of Microglial Cells in Cerebral Ischemia

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Resveratrol Activates Neuronal Autophagy Through AMPK in the Ischemic Brain

(2019) Narayana Pineda-Ramírez et al.   MOLECULAR NEUROBIOLOGY

Complement dysregulation in the central nervous system during development and disease

(2019) John D. Lee et al.   SEMINARS IN IMMUNOLOGY

The CNS Immune Landscape from the Viewpoint of a T Cell

(2019) Sarah Mundt et al.   TRENDS IN NEUROSCIENCES

TGFβ blocks IFNα/β release and tumor rejection in spontaneous mammary tumors

(2019) Marion V. Guerin et al.   Nature Communications

Stimulator of interferon genes (STING) activation exacerbates experimental colitis in mice

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Innate Immune Response to Cytoplasmic DNA: Mechanisms and Diseases

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Blocking AMPK/ULK1-dependent autophagy promoted apoptosis and suppressed colon cancer growth

(2019) Jing Liu et al.   Cancer Cell International

Inflammatory Pathways Following Subarachnoid Hemorrhage

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Critical Role of Cytosolic DNA and Its Sensing Adaptor STING in Aortic Degeneration, Dissection, and Rupture

(2019) Wei Luo et al.   CIRCULATION

HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING

(2019) Xiaobo Luo et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry Perspective

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Innate immunity activation in the early brain injury period following subarachnoid hemorrhage

(2019) Typhaine Gris et al.   Journal of Neuroinflammation

Apelin-13/APJ system attenuates early brain injury via suppression of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation and oxidative stress in a AMPK-dependent manner after subarachnoid hemorrhage in rats

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LSD1 mediates microbial metabolite butyrate-induced thermogenesis in brown and white adipose tissue

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Dihydrolipoic Acid–Gold Nanoclusters Regulate Microglial Polarization and Have the Potential To Alter Neurogenesis

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Pericytes: Problems and Promises for CNS Repair

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Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks

(2019) Benjamin D. Stein et al.   Cell Reports

Neuroinflammation as a Factor of Neurodegenerative Disease: Thalidomide Analogs as Treatments

(2019) Yoo Jin Jung et al.   Frontiers in Cell and Developmental Biology

TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue

(2018) Peng Zhao et al.   CELL

Activation of the STING-IRF3 pathway promotes hepatocyte inflammation, apoptosis and induces metabolic disorders in nonalcoholic fatty liver disease

(2018) J.T. Qiao et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Breast cancer susceptibility protein 1 (BRCA1) rescues neurons from cerebral ischemia/reperfusion injury through NRF2-mediated antioxidant pathway

(2018) Pengfei Xu et al.   Redox Biology

Mesencephalic astrocyte-derived neurotrophic factor affords neuroprotection to early brain injury induced by subarachnoid hemorrhage via activating Akt-dependent prosurvival pathway and defending blood–brain barrier integrity

(2018) Tao Li et al.   FASEB JOURNAL

TSG-6 attenuates inflammation-induced brain injury via modulation of microglial polarization in SAH rats through the SOCS3/STAT3 pathway

(2018) Ran Li et al.   Journal of Neuroinflammation

Recombinant CTRP9 administration attenuates neuroinflammation via activating adiponectin receptor 1 after intracerebral hemorrhage in mice

(2018) Lianhua Zhao et al.   Journal of Neuroinflammation

Targeting STING with covalent small-molecule inhibitors

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STING-mediated type-I interferons contribute to the neuroinflammatory process and detrimental effects following traumatic brain injury

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A mathematical model of neuroinflammation in severe clinical traumatic brain injury

(2018) Leah E. Vaughan et al.   Journal of Neuroinflammation

STING-dependent sensing of self-DNA drives silica-induced lung inflammation

(2018) Sulayman Benmerzoug et al.   Nature Communications

CD163 Expression in Neurons After Experimental Intracerebral Hemorrhage

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Melatonin attenuated early brain injury induced by subarachnoid hemorrhage via regulating NLRP3 inflammasome and apoptosis signaling

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Functions and mechanisms of microglia/macrophages in neuroinflammation and neurogenesis after stroke

(2016) Xiao-Yi Xiong et al.   PROGRESS IN NEUROBIOLOGY

Curcumin prophylaxis mitigates the incidence of hypobaric hypoxia-induced altered ion channels expression and impaired tight junction proteins integrity in rat brain

(2015) SKS Sarada et al.   Journal of Neuroinflammation

Matched Cohort Analysis of the Effects of Limb Remote Ischemic Conditioning in Patients with Aneurysmal Subarachnoid Hemorrhage

(2015) Azim N. Laiwalla et al.   Translational Stroke Research

A new grading system evaluating bleeding scale in filament perforation subarachnoid hemorrhage rat model

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