Discovery of novel L-type voltage-gated calcium channel blockers and application for the prevention of inflammation and angiogenesis

Mitochondria, Microglia, and the Immune System—How Are They Linked in Affective Disorders?

(2019) Carsten Culmsee et al.   Frontiers in Psychiatry

Time-dependent LXR/RXR pathway modulation characterizes capillary remodeling in inflammatory corneal neovascularization

(2018) Anthony Mukwaya et al.   ANGIOGENESIS

Selective IKK2 inhibitor IMD0354 disrupts NF-κB signaling to suppress corneal inflammation and angiogenesis

(2018) Anton Lennikov et al.   ANGIOGENESIS

Microglia in Alzheimer’s Disease: Activated, Dysfunctional or Degenerative

(2018) Victoria Navarro et al.   Frontiers in Aging Neuroscience

Tissue-specific Role of CX3CR1 Expressing Immune Cells and Their Relationships with Human Disease

(2018) Myoungsoo Lee et al.   Immune Network

In Vivo Imaging of Microglial Calcium Signaling in Brain Inflammation and Injury

(2017) Petr Tvrdik et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Novel 1, 4-dihydropyridines for L-type calcium channel as antagonists for cadmium toxicity

(2017) Madhu Sudhana Saddala et al.   Scientific Reports

Regulation of Integrin α6 Recycling by Calcium-independent Phospholipase A2(iPLA2) to Promote Microglia Chemotaxis on Laminin

(2016) Sang-Hyun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A microarray whole-genome gene expression dataset in a rat model of inflammatory corneal angiogenesis

(2016) Anthony Mukwaya et al.   Scientific Data

Factors regulating capillary remodeling in a reversible model of inflammatory corneal angiogenesis

(2016) Anthony Mukwaya et al.   Scientific Reports

The L-type voltage-gated calcium channel modulates microglial pro-inflammatory activity

(2015) J.F. Espinosa-Parrilla et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The Role of Ion Channels in Microglial Activation and Proliferation – A Complex Interplay between Ligand-Gated Ion Channels, K+ Channels, and Intracellular Ca2+

(2015) Martin James Stebbing et al.   Frontiers in Immunology

Estrogen Receptor Inhibits Mineralocorticoid Receptor Transcriptional Regulatory Function

(2014) Katelee Barrett Mueller et al.   ENDOCRINOLOGY

The Degree of Resistance of Erythrocyte Membrane Cytoskeletal Proteins to Supra-Physiologic Concentrations of Calcium: An In Vitro Study

(2014) Ebrahim Mostafavi et al.   JOURNAL OF MEMBRANE BIOLOGY

Calcineurin and glial signaling: neuroinflammation and beyond

(2014) Jennifer L Furman et al.   Journal of Neuroinflammation

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed

(2014) Jonathan D Cherry et al.   Journal of Neuroinflammation

Calcium-Calmodulin-Dependent Protein Kinase II Isoforms Differentially Impact the Dynamics and Structure of the Actin Cytoskeleton

(2013) Laurel Hoffman et al.   BIOCHEMISTRY

Microglial calcium signaling in the adult, aged and diseased brain

(2013) Bianca Brawek et al.   CELL CALCIUM

The microglial activation state regulates migration and roles of matrix-dissolving enzymes for invasion

(2013) Starlee Lively et al.   Journal of Neuroinflammation

VEGF Receptor Blockade Markedly Reduces Retinal Microglia/Macrophage Infiltration into Laser-Induced CNV

(2013) Hu Huang et al.   PLoS One

Ca2+ release-activated Ca2+ (CRAC) current, structure, and function

(2012) Martin Muik et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The NF-κB Signaling Protein Bcl10 Regulates Actin Dynamics by Controlling AP1 and OCRL-Bearing Vesicles

(2012) Sabrina Marion et al.   DEVELOPMENTAL CELL

Oxidative Stress and Microglial Cells in Parkinson's Disease

(2012) Lynda J. Peterson et al.   MEDIATORS OF INFLAMMATION

Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors

(2012) Amy McCurley et al.   NATURE MEDICINE

Inhibition of human astrocyte and microglia neurotoxicity by calcium channel blockers

(2012) Sadayuki Hashioka et al.   NEUROPHARMACOLOGY

Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases

(2011) Joshua A. Smith et al.   BRAIN RESEARCH BULLETIN

Ion Channels on Microglia: Therapeutic Targets for Neuroprotection

(2011) Stephen D. Skaper   CNS & Neurological Disorders-Drug Targets

Toward in silico structure-based ADMET prediction in drug discovery

(2011) Gautier Moroy et al.   DRUG DISCOVERY TODAY

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Purinergic Signaling Induces Cyclooxygenase-1-Dependent Prostanoid Synthesis in Microglia: Roles in the Outcome of Excitotoxic Brain Injury

(2011) Josef Anrather et al.   PLoS One

Nifedipine, a calcium channel blocker, inhibits inflammatory and fibrogenic gene expressions in advanced glycation end product (AGE)-exposed fibroblasts via mineralocorticoid receptor antagonistic activity

(2010) Takanori Matsui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Verapamil protects dopaminergic neuron damage through a novel anti-inflammatory mechanism by inhibition of microglial activation

(2010) Yuxin Liu et al.   NEUROPHARMACOLOGY

Heterogeneity in function of small artery smooth muscle BKCa: involvement of the β1-subunit

(2009) Yan Yang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Nicardipine: A Hypotensive Dihydropyridine-Type Calcium Antagonist with a Peculiar Cerebrovascular Profile

(2008) Francesco Amenta et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Microglial cells and Parkinson’s disease

(2008) Li Qian et al.   IMMUNOLOGIC RESEARCH

Nimodipine protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation

(2008) Yachen Li et al.   NEUROPHARMACOLOGY