A novel lncRNA PLK4 up‐regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP‐mediated cell senescence

The complex entanglement of Hippo-Yap/Taz signaling in tumor immunity

(2019) Shannon M. White et al.   ONCOGENE

Usp7 regulates Hippo pathway through deubiquitinating the transcriptional coactivator Yorkie

(2019) Xiaohan Sun et al.   Nature Communications

MITA1, a novel energy stress-inducible lncRNA, promotes hepatocellular carcinoma metastasis

(2019) Meilin Ma et al.   HEPATOLOGY

Lnc-UCID promotes G1/S transition and hepatoma growth by preventing DHX9-mediated CDK6 downregulation

(2019) Yun-Long Wang et al.   HEPATOLOGY

YAP1‐LATS2 feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis

(2019) Chunbo He et al.   EMBO REPORTS

Long Noncoding RNA MALAT1 regulates cancer glucose metabolism by enhancing mTOR-mediated translation of TCF7L2

(2019) Pushkar Malakar et al.   CANCER RESEARCH

Genome-wide screening and functional analysis identifies tumor suppressor long non-coding RNAs epigenetically silenced in hepatocellular carcinoma

(2019) Feiyue Xu et al.   CANCER RESEARCH

Long non‐coding RNA ES 1 controls the proliferation of breast cancer cells by regulating the Oct4/Sox2/miR‐302 axis

(2019) Mostafa Keshavarz et al.   FEBS Journal

Surveillance for Hepatocellular Carcinoma: Current Best Practice and Future Direction

(2019) Fasiha Kanwal et al.   GASTROENTEROLOGY

Cholangiocyte‐Derived Exosomal Long Noncoding RNA H19 Promotes Hepatic Stellate Cell Activation and Cholestatic Liver Fibrosis

(2019) Runping Liu et al.   HEPATOLOGY

The Roles of YAP/TAZ and the Hippo Pathway in Healthy and Diseased Skin

(2019) Emanuel Rognoni et al.   Cells

Oroxylin A inhibits ethanol-induced hepatocyte senescence via  YAP pathway

(2018) Huanhuan Jin et al.   CELL PROLIFERATION

High mobility group protein B1 controls liver cancer initiation through yes-associated protein -dependent aerobic glycolysis

(2018) Ruochan Chen et al.   HEPATOLOGY

Hippo-mediated suppression of IRS2/AKT signaling prevents hepatic steatosis and liver cancer

(2018) Sun-Hye Jeong et al.   JOURNAL OF CLINICAL INVESTIGATION

Non-coding RNAs in hepatocellular carcinoma: molecular functions and pathological implications

(2018) Chun-Ming Wong et al.   Nature Reviews Gastroenterology & Hepatology

Regulation of Yki/Yap subcellular localization and Hpo signaling by a nuclear kinase PRP4K

(2018) Yong suk Cho et al.   Nature Communications

Ultraconserved element uc.372 drives hepatic lipid accumulation by suppressing miR-195/miR4668 maturation

(2018) Jun Guo et al.   Nature Communications

Yap promotes hepatocellular carcinoma metastasis and mobilization via governing cofilin/F-actin/lamellipodium axis by regulation of JNK/Bnip3/SERCA/CaMKII pathways

(2018) Chen Shi et al.   Redox Biology

Targeting the Hippo Pathway and Cancer through the TEAD Family of Transcription Factors

(2018) et al.   Cancers

LncRNA CDKN2B-AS1 promotes tumor growth and metastasis of human hepatocellular carcinoma by targeting let-7c-5p/NAP1L1 axis

(2018) Yuqi Huang et al.   CANCER LETTERS

Long Noncoding RNA Lnc-SEMT Modulates IGF2 Expression by Sponging miR-125b to Promote Sheep Muscle Development and Growth

(2018) Caihong Wei et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Necroptosis microenvironment directs lineage commitment in liver cancer

(2018) Marco Seehawer et al.   NATURE

Talazoparib in Patients with Advanced Breast Cancer and a Germline BRCA Mutation

(2018) Jennifer K. Litton et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Phase II Study of Talazoparib After Platinum or Cytotoxic Nonplatinum Regimens in Patients With Advanced Breast Cancer and Germline BRCA1/2 Mutations (ABRAZO)

(2018) Nicholas C. Turner et al.   CLINICAL CANCER RESEARCH

Overexpression of Rac GTPase Activating Protein 1 Contributes to Proliferation of Cancer Cells by Reducing Hippo Signaling to Promote Cytokinesis

(2018) Xiao-Mei Yang et al.   GASTROENTEROLOGY

DEAD Box Protein 5 Inhibits Liver Tumorigenesis by Stimulating Autophagy via Interaction with p62/SQSTM1

(2018) Hao Zhang et al.   HEPATOLOGY

Four long noncoding RNAs as potential prognostic biomarkers for hepatocellular carcinoma

(2018) Jianchu Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hippo–YAP/TAZ signalling in organ regeneration and regenerative medicine

(2018) Iván M. Moya et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inhibition of YAP signaling contributes to senescence of hepatic stellate cells induced by tetramethylpyrazine

(2017) Huanhuan Jin et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Liver Cancer Cell of Origin, Molecular Class, and Effects on Patient Prognosis

(2017) Daniela Sia et al.   GASTROENTEROLOGY

A novel lncRNA uc.134 represses hepatocellular carcinoma progression by inhibiting CUL4A-mediated ubiquitination of LATS1

(2017) Wen Ni et al.   Journal of Hematology & Oncology

The noncoding RNA HOXD-AS1 is a critical regulator of the metastasis and apoptosis phenotype in human hepatocellular carcinoma

(2017) Shan Lu et al.   Molecular Cancer

Lnc-ing ROR1–HER3 and Hippo signalling in metastasis

(2017) Wei Zhuo et al.   NATURE CELL BIOLOGY

Long non-coding RNAs involved in autophagy regulation

(2017) Lixian Yang et al.   Cell Death & Disease

RBM5-AS1 Is Critical for Self-Renewal of Colon Cancer Stem-like Cells

(2016) Serena Di Cecilia et al.   CANCER RESEARCH

PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer

(2016) Benjamin H. Lok et al.   CLINICAL CANCER RESEARCH

Aspartate β-hydroxylase modulates cellular senescence through glycogen synthase kinase 3β in hepatocellular carcinoma

(2016) Yoshifumi Iwagami et al.   HEPATOLOGY

LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells

(2016) Pingping Zhu et al.   Nature Communications

The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies

(2015) Luping Lin et al.   NATURE GENETICS

Mutual inhibition between YAP and SRSF1 maintains long non-coding RNA, Malat1-induced tumourigenesis in liver cancer

(2014) Jiayi Wang et al.   CELLULAR SIGNALLING

Reduced expression of transcriptional intermediary factor 1 gamma promotes metastasis and indicates poor prognosis of hepatocellular carcinoma

(2014) Ze-yang Ding et al.   HEPATOLOGY

YAP activation is an early event and a potential therapeutic target in liver cancer development

(2014) Andrea Perra et al.   JOURNAL OF HEPATOLOGY

Long non-coding RNAs: A new frontier in the study of human diseases

(2013) Xuefei Shi et al.   CANCER LETTERS

YAP/TEAD-Mediated Transcription Controls Cellular Senescence

(2013) Q. Xie et al.   CANCER RESEARCH

Suppressing N-Myc downstream regulated gene 1 reactivates senescence signaling and inhibits tumor growth in hepatocellular carcinoma

(2013) Wen-Jing Lu et al.   CARCINOGENESIS

Long Noncoding RNAs: Cellular Address Codes in Development and Disease

(2013) Pedro J. Batista et al.   CELL

Negative regulation of transcription factor FoxM1 by p53 enhances oxaliplatin-induced senescence in hepatocellular carcinoma

(2012) Kai Qu et al.   CANCER LETTERS

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

(2011) Kevin C. Wang et al.   NATURE