Long non-coding RNAs involved in autophagy regulation

GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration

(2017) Shuji Wakatsuki et al.   JOURNAL OF CELL BIOLOGY

LncRNA MALAT-1 Elevates HMGB1 to Promote Autophagy Resulting in Inhibition of Tumor Cell Apoptosis in Multiple Myeloma

(2017) Da Gao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Long noncoding RNAs and sulforaphane: a target for chemoprevention and suppression of prostate cancer

(2017) Laura M. Beaver et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Sanguinarine protects against ovariectomy-induced osteoporosis in mice

(2017) Yan Ma et al.   Molecular Medicine Reports

Long noncoding RNA Malat1 is a potent autophagy inducer protecting brain microvascular endothelial cells against oxygen-glucose deprivation/reoxygenation-induced injury by sponging miR-26b and upregulating ULK2 expression

(2017) Zhijun Li et al.   NEUROSCIENCE

LncRNA HULC triggers autophagy via stabilizing Sirt1 and attenuates the chemosensitivity of HCC cells

(2017) H Xiong et al.   ONCOGENE

Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy

(2017) Bo Wu et al.   Cell Death & Disease

Knockdown of long non-coding RNA HOTAIR increases miR-454-3p by targeting Stat3 and Atg12 to inhibit chondrosarcoma growth

(2017) Xing Bao et al.   Cell Death & Disease

Long Non-coding RNA H19 Induces Cerebral Ischemia Reperfusion Injury via Activation of Autophagy

(2017) Jue Wang et al.   Aging and Disease

Three intronic lncRNAs with monoallelic expression derived from the MEG8 gene in cattle

(2016) W. Yang et al.   ANIMAL GENETICS

Emerging connections between RNA and autophagy

(2016) Lisa B. Frankel et al.   Autophagy

MIR144* inhibits antimicrobial responses against Mycobacterium tuberculosis in human monocytes and macrophages by targeting the autophagy protein DRAM2

(2016) Jin Kyung Kim et al.   Autophagy

Autophagy ameliorates cognitive impairment through activation of PVT1 and apoptosis in diabetes mice

(2016) Zhigui Li et al.   BEHAVIOURAL BRAIN RESEARCH

Long non-coding RNA HNF1A-AS1 functioned as an oncogene and autophagy promoter in hepatocellular carcinoma through sponging hsa-miR-30b-5p

(2016) Zhiqian Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The HIF-2α-MALAT1-miR-216b axis regulates multi-drug resistance of hepatocellular carcinoma cells via modulating autophagy

(2016) Peng Yuan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

An lncRNA switch for AMPK activation

(2016) Xiaowen Liu et al.   CELL CYCLE

The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway

(2016) Zhen-Hua Chen et al.   CELL DEATH AND DIFFERENTIATION

Down-regulation of Risa improves insulin sensitivity by enhancing autophagy

(2016) Yuangao Wang et al.   FASEB JOURNAL

The long noncoding RNA HOTAIR activates autophagy by upregulating ATG3 and ATG7 in hepatocellular carcinoma

(2016) Liang Yang et al.   Molecular BioSystems

Long Noncoding RNA MALAT1 Promotes Aggressive Pancreatic Cancer Proliferation and Metastasis via the Stimulation of Autophagy

(2016) L. Li et al.   MOLECULAR CANCER THERAPEUTICS

LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress

(2016) Xiaowen Liu et al.   NATURE CELL BIOLOGY

Unique features of long non-coding RNA biogenesis and function

(2016) Jeffrey J. Quinn et al.   NATURE REVIEWS GENETICS

Expansion of antisense lncRNA transcriptomes in budding yeast species since the loss of RNAi

(2016) Eric A Alcid et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Long noncoding RNA Chast promotes cardiac remodeling

(2016) Janika Viereck et al.   Science Translational Medicine

Autophagy regulates resistance of non-small cell lung cancer cells to paclitaxel

(2016) Kan Chen et al.   TUMOR BIOLOGY

Snail-activated long non-coding RNA PCA3 up-regulates PRKD3 expression by miR-1261 sponging, thereby promotes invasion and migration of prostate cancer cells

(2016) Jin-Hua He et al.   TUMOR BIOLOGY

Expansion of antisense lncRNA transcriptomes in budding yeast species since the loss of RNAi

(2016) Eric A Alcid et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Large intergenic non-coding RNA-ROR reverses gemcitabine-induced autophagy and apoptosis in breast cancer cells

(2016) Yao-Min Chen et al.   Oncotarget

Therapeutic strategy with artificially-designed i-lncRNA targeting multiple oncogenic microRNAs exhibits effective antitumor activity in diffuse large B-cell lymphoma

(2016) Yinghan Su et al.   Oncotarget

Identification of the lncRNA, AK156230, as a novel regulator of cellular senescence in mouse embryonic fibroblasts

(2016) Yu-ning Chen et al.   Oncotarget

Analysis of Microarray Data on Gene Expression and Methylation to Identify Long Non-coding RNAs in Non-small Cell Lung Cancer

(2016) Nannan Feng et al.   Scientific Reports

Down regulated lncRNA MEG3 eliminates mycobacteria in macrophages via autophagy

(2016) Kamlesh Pawar et al.   Scientific Reports

A new microRNA signal pathway regulated by long noncoding RNA TGFB2-OT1 in autophagy and inflammation of vascular endothelial cells

(2015) ShuYa Huang et al.   Autophagy

How the Atg1 complex assembles to initiate autophagy

(2015) Christopher W Davies et al.   Autophagy

Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy

(2015) Agnete Bratsberg Eriksen et al.   Autophagy

Suppression of hepatocellular carcinoma by baculovirus-mediated expression of long non-coding RNA PTENP1 and MicroRNA regulation

(2015) Chiu-Ling Chen et al.   BIOMATERIALS

miR-26a enhances autophagy to protect against ethanol-induced acute liver injury

(2015) Weidong Han et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

PCGEM1 stimulates proliferation of osteoarthritic synoviocytes by acting as a sponge for miR-770

(2015) Yeonho Kang et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

HOTAIR Long Noncoding RNA Promotes Gastric Cancer Metastasis through Suppression of Poly r(C)-Binding Protein (PCBP) 1

(2015) Z.-Z. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

PLEKHM1 Regulates Autophagosome-Lysosome Fusion through HOPS Complex and LC3/GABARAP Proteins

(2015) David G. McEwan et al.   MOLECULAR CELL

Autophagy and autophagy-related proteins in the immune system

(2015) Shusaku T Shibutani et al.   NATURE IMMUNOLOGY

Emerging strategies to effectively target autophagy in cancer

(2015) V W Rebecca et al.   ONCOGENE

miR-494 promotes cell proliferation, migration and invasion, and increased sorafenib resistance in hepatocellular carcinoma by targeting PTEN

(2015) KAI LIU et al.   ONCOLOGY REPORTS

LincHOTAIR epigenetically silences miR34a by binding to PRC2 to promote the epithelial-to-mesenchymal transition in human gastric cancer

(2015) Y-w Liu et al.   Cell Death & Disease

APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p

(2015) Kun Wang et al.   Nature Communications

MiR-21 mediates sorafenib resistance of hepatocellular carcinoma cells by inhibiting autophagy via the PTEN/Akt pathway

(2015) Changjun He et al.   Oncotarget

Minor Loops in Major Folds: Enhancer–Promoter Looping, Chromatin Restructuring, and Their Association with Transcriptional Regulation and Disease

(2015) Navneet Matharu et al.   PLoS Genetics

Autophagy: A Novel Therapeutic Target for Diabetic Nephropathy

(2015) Shinji Kume et al.   Diabetes & Metabolism Journal

LAMP-2: A control step for phagosome and autophagosome maturation

(2014) Paul Saftig et al.   Autophagy

Atg14L and Rubicon: Yin and yang of Beclin 1-mediated autophagy control

(2014) Zhong Yun et al.   Autophagy

BCL2 and related prosurvival proteins require BAK1 and BAX to affect autophagy

(2014) Lisa M Lindqvist et al.   Autophagy

Identification of a novel MTOR activator and discovery of a competing endogenous RNA regulating autophagy in vascular endothelial cells

(2014) Di Ge et al.   Autophagy

Atg1 kinase organizes autophagosome formation by phosphorylating Atg9

(2014) Daniel Papinski et al.   Autophagy

The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

(2014) David Heras-Sandoval et al.   CELLULAR SIGNALLING

The protein-vesicle network of autophagy

(2014) Liang Ge et al.   CURRENT OPINION IN CELL BIOLOGY

A long non-coding RNA, GAS5, plays a critical role in the regulation of miR-21 during osteoarthritis

(2014) Jinsoo Song et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Long non-coding RNA HOTAIR, a c-Myc activated driver of malignancy, negatively regulates miRNA-130a in gallbladder cancer

(2014) Ming-zhe Ma et al.   Molecular Cancer

Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer

(2014) Xiang-hua Liu et al.   Molecular Cancer

Pseudogene PTENP1 Functions as a Competing Endogenous RNA to Suppress Clear-Cell Renal Cell Carcinoma Progression

(2014) G. Yu et al.   MOLECULAR CANCER THERAPEUTICS

The multilayered complexity of ceRNA crosstalk and competition

(2014) Yvonne Tay et al.   NATURE

7SL RNA represses p53 translation by competing with HuR

(2014) Kotb Abdelmohsen et al.   NUCLEIC ACIDS RESEARCH

mTOR and autophagy: A dynamic relationship governed by nutrients and energy

(2014) E.A. Dunlop et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Functional interactions among microRNAs and long noncoding RNAs

(2014) Je-Hyun Yoon et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells

(2013) Yuan-Fei Peng et al.   Autophagy

Gene regulation by the act of long non-coding RNA transcription

(2013) Aleksandra E Kornienko et al.   BMC BIOLOGY

Crohn's Disease–Associated Adherent Invasive Escherichia coli Modulate Levels of microRNAs in Intestinal Epithelial Cells to Reduce Autophagy

(2013) Hang Thi Thu Nguyen et al.   GASTROENTEROLOGY

Autophagic Processes in Yeast: Mechanism, Machinery and Regulation

(2013) F. Reggiori et al.   GENETICS

MicroRNA-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer

(2013) Hongping Xia et al.   HEPATOLOGY

CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion

(2013) H. J. k. Balderhaar et al.   JOURNAL OF CELL SCIENCE

Fine mapping of autophagy-related proteins during autophagosome formation in Saccharomyces cerevisiae

(2013) K. Suzuki et al.   JOURNAL OF CELL SCIENCE

MicroRNA-30b functions as a tumour suppressor in human colorectal cancer by targetingKRAS,PIK3CDandBCL2

(2013) Wen-Ting Liao et al.   JOURNAL OF PATHOLOGY

The return of the nucleus: transcriptional and epigenetic control of autophagy

(2013) Jens Füllgrabe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts

(2013) Sarah Geisler et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of long non-coding RNA HULC in cell proliferation, apoptosis and tumor metastasis of gastric cancer: A clinical and in vitro investigation

(2013) YAN ZHAO et al.   ONCOLOGY REPORTS

Identification and function of long non-coding RNA

(2013) Carl Ernst et al.   Frontiers in Cellular Neuroscience

Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells

(2013) W-T Tai et al.   Cell Death & Disease

ceRNA Cross-Talk in Cancer: When ce-bling Rivalries Go Awry

(2013) F. A. Karreth et al.   Cancer Discovery

Genome Regulation by Long Noncoding RNAs

(2012) John L. Rinn et al.   Annual Review of Biochemistry

Compromised autophagy byMIR30Bbenefits the intracellular survival ofHelicobacter pylori

(2012) Bin Tang et al.   Autophagy

MiR-20a and miR-106b negatively regulate autophagy induced by leucine deprivation via suppression of ULK1 expression in C2C12 myoblasts

(2012) Hao Wu et al.   CELLULAR SIGNALLING

Posttranscriptional Gene Regulation by Long Noncoding RNA

(2012) Je-Hyun Yoon et al.   JOURNAL OF MOLECULAR BIOLOGY

Downregulated MEG3 activates autophagy and increases cell proliferation in bladder cancer

(2012) Liang Ying et al.   Molecular BioSystems

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

(2012) Congcong He et al.   NATURE

Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy

(2012) R David Sentelle et al.   Nature Chemical Biology

Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

(2012) Kook Hwan Kim et al.   NATURE MEDICINE

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein

(2011) Zhuo Wang et al.   Autophagy

Interferon-gamma induces autophagy with growth inhibition and cell death in human hepatocellular carcinoma (HCC) cells through interferon-regulatory factor-1 (IRF-1)

(2011) Peiyuan Li et al.   CANCER LETTERS

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Non-coding RNAs in human disease

(2011) Manel Esteller   NATURE REVIEWS GENETICS

Functional Characterization of the Plasmacytoma Variant Translocation 1 Gene (PVT1) in Diabetic Nephropathy

(2011) M. Lucrecia Alvarez et al.   PLoS One

Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein

(2010) P. Isakson et al.   BLOOD

The Beclin 1 interactome

(2010) Congcong He et al.   CURRENT OPINION IN CELL BIOLOGY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

(2010) Laura Poliseno et al.   NATURE

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Noncoding RNA Gas5 Is a Growth Arrest- and Starvation-Associated Repressor of the Glucocorticoid Receptor

(2010) T. Kino et al.   Science Signaling

A myelopoiesis-associated regulatory intergenic noncoding RNA transcript within the human HOXA cluster

(2009) X. Zhang et al.   BLOOD

The late stages of autophagy: how does the end begin?

(2009) T Noda et al.   CELL DEATH AND DIFFERENTIATION

Highly upregulated in liver cancer noncoding RNA is overexpressed in hepatic colorectal metastasis

(2009) Imad J. Matouk et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Dimeric Coiled-coil Structure ofSaccharomyces cerevisiaeAtg16 and Its Functional Significance in Autophagy

(2009) Yuko Fujioka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamics and diversity in autophagy mechanisms: lessons from yeast

(2009) Hitoshi Nakatogawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

(2009) Ahmad M. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

(2008) Elizabeth L. Axe et al.   JOURNAL OF CELL BIOLOGY

E2F1 regulates autophagy and the transcription of autophagy genes

(2008) S Polager et al.   ONCOGENE