Cholangiocyte‐Derived Exosomal Long Noncoding RNA H19 Promotes Hepatic Stellate Cell Activation and Cholestatic Liver Fibrosis

Mechanisms of cholangiocyte responses to injury

(2018) Keisaku Sato et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Exosomes in cancer development and clinical applications

(2018) Yu-Ling Tai et al.   CANCER SCIENCE

Cholangiocyte-derived exosomal long noncoding RNA H19 promotes cholestatic liver injury in mouse and humans

(2018) Xiaojiaoyang Li et al.   HEPATOLOGY

The lncRNA H19 Mediates Pulmonary Fibrosis by Regulating the miR-196a/COL1A1 Axis

(2018) Qingchun Lu et al.   INFLAMMATION

Exosome Theranostics: Biology and Translational Medicine

(2018) Chuanjiang He et al.   Theranostics

Ductular reaction in liver diseases: pathological mechanisms and translational significances

(2018) Keisaku Sato et al.   HEPATOLOGY

Engineered Exosomes With Ischemic Myocardium‐Targeting Peptide for Targeted Therapy in Myocardial Infarction

(2018) Xu Wang et al.   Journal of the American Heart Association

H19/miR-148a/USP4 axis facilitates liver fibrosis by enhancing TGF-β signaling in both hepatic stellate cells and hepatocytes

(2018) Jie Zhu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Glycyrrhetic acid, but not glycyrrhizic acid, strengthened entecavir activity by promoting its subcellular distribution in the liver via efflux inhibition

(2017) Qianying Chen et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Hepatocyte-derived exosomes promote T follicular regulatory cell expansion during hepatitis C virus infection

(2017) Dustin A. Cobb et al.   HEPATOLOGY

The role of long noncoding RNA H19 in gender disparity of cholestatic liver injury in multidrug resistance 2 gene knockout mice

(2017) Xiaojiaoyang Li et al.   HEPATOLOGY

The role of sphingosine 1-phosphate receptor 2 in bile-acid-induced cholangiocyte proliferation and cholestasis-induced liver injury in mice

(2017) Yongqing Wang et al.   HEPATOLOGY

Role of exosomal proteins in cancer diagnosis

(2017) Weihua Li et al.   Molecular Cancer

Mechanisms of hepatic stellate cell activation

(2017) Takuma Tsuchida et al.   Nature Reviews Gastroenterology & Hepatology

Long noncoding RNA H19 controls DUSP5/ERK1/2 axis in cardiac fibroblast proliferation and fibrosis

(2016) Hui Tao et al.   CARDIOVASCULAR PATHOLOGY

Exosome-encapsulated microRNAs as circulating biomarkers for breast cancer

(2016) Doireann P. Joyce et al.   INTERNATIONAL JOURNAL OF CANCER

Exosomes in the Pathology of Neurodegenerative Diseases

(2016) Jason Howitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosomes in liver pathology

(2016) Keisaku Sato et al.   JOURNAL OF HEPATOLOGY

Exosome RNA expression predicts high-grade disease

(2016) Louise Stone   Nature Reviews Urology

Roles, Functions, and Mechanisms of Long Non-coding RNAs in Cancer

(2016) Yiwen Fang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

The Cholangiopathies

(2015) Konstantinos N. Lazaridis et al.   MAYO CLINIC PROCEEDINGS

The H19 Long non-coding RNA in cancer initiation, progression and metastasis – a proposed unifying theory

(2015) Eli Raveh et al.   Molecular Cancer

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

H19-derived miR-675 contributes to bladder cancer cell proliferation by regulating p53 activation

(2015) Changkun Liu et al.   TUMOR BIOLOGY

HCV transmission by hepatic exosomes establishes a productive infection

(2013) François-Loïc Cosset et al.   JOURNAL OF HEPATOLOGY

Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity

(2013) Jianhua Li et al.   NATURE IMMUNOLOGY

Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases

(2012) Shashi Bala et al.   HEPATOLOGY

The dynamic biliary epithelia: Molecules, pathways, and disease

(2012) Steven P. O’Hara et al.   JOURNAL OF HEPATOLOGY

Exosome-mediated delivery of siRNA in vitro and in vivo

(2012) Samir El-Andaloussi et al.   Nature Protocols

Exosome target cell selection and the importance of exosomal tetraspanins: a hypothesis

(2011) Sanyukta Rana et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Interaction and uptake of exosomes by ovarian cancer cells

(2011) Cristina Escrevente et al.   BMC CANCER

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia

(2010) Anatoliy I. Masyuk et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Liver Cell–Derived Microparticles Activate Hedgehog Signaling and Alter Gene Expression in Hepatic Endothelial Cells

(2008) Rafal P. Witek et al.   GASTROENTEROLOGY