Responsive Fluorescent PNA Analogue as a Tool for Detecting G-quadruplex Motifs of Oncogenes and Activity of Toxic Ribosome-Inactivating Proteins

A Water-Soluble Tetraazaperopyrene Dye as Strong G-Quadruplex DNA Binder

(2016) Lena Hahn et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Bis(methylpiperazinylstyryl)phenanthroline as a Fluorescent Ligand for G-Quadruplexes

(2016) Shangrong Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Self-Assembled Hybrid Aptamer-Fc Conjugates for Targeted Delivery: A Modular Chemoenzymatic Approach

(2015) Stephan Dickgiesser et al.   ACS Chemical Biology

Positional Impact of Fluorescently Modified G-Tetrads within Polymorphic Human Telomeric G-Quadruplex Structures

(2015) Michael Sproviero et al.   ACS Chemical Biology

A Fluorescent Adenosine Analogue as a Substrate for an A-to-I RNA Editing Enzyme

(2015) Rena A. Mizrahi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hybridization-Sensitive Fluorescent Oligonucleotide Probe Conjugated with a Bulky Module for Compartment-Specific mRNA Monitoring in a Living Cell

(2015) Gosuke Hayashi et al.   BIOCONJUGATE CHEMISTRY

PNA–Rose Bengal Conjugates as Efficient DNA Photomodulators

(2015) Yossi Shemesh et al.   BIOCONJUGATE CHEMISTRY

A fluorescent G-quadruplex probe for the assay of base excision repair enzyme activity

(2015) Chang Yeol Lee et al.   CHEMICAL COMMUNICATIONS

Targeting G-quadruplex structures with extrinsic fluorogenic dyes: promising fluorescence sensors

(2015) Achikanath C. Bhasikuttan et al.   CHEMICAL COMMUNICATIONS

In Vitro Reversible Translation Control Using γPNA Probes

(2015) Taylor D. Canady et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gamma Peptide Nucleic Acids: As Orthogonal Nucleic Acid Recognition Codes for Organizing Molecular Self-Assembly

(2015) Iulia Sacui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visualization of RNA-Quadruplexes in Live Cells

(2015) Aurélien Laguerre et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conquering 2-Aminopurine’s Deficiencies: Highly Emissive Isomorphic Guanosine Surrogate Faithfully Monitors Guanosine Conformation and Dynamics in DNA

(2015) Marianna Sholokh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorescent Probe for Proton-Coupled DNA Folding Revealing Slow Exchange of i-Motif and Duplex Structures

(2015) Guillaume Mata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conformation-sensitive nucleoside analogues as topology-specific fluorescence turn-on probes for DNA and RNA G-quadruplexes

(2015) Arun A. Tanpure et al.   NUCLEIC ACIDS RESEARCH

Strand displacement and duplex invasion into double-stranded DNA by pyrrolidinyl peptide nucleic acids

(2015) Peggy R. Bohländer et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

2-aminopurine as a fluorescent probe of DNA conformation and the DNA–enzyme interface

(2015) Anita C. Jones et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Design and synthesis of 7-naphthyl-8-aza-7-deaza-2′-deoxyadenosines as environmentally sensitive fluorescent nucleosides

(2015) Yoshio Saito et al.   TETRAHEDRON LETTERS

Recent Progress in Abasic Site-binding Small Molecules for Detecting Single-base Mutations in DNA

(2014) Seiichi NISHIZAWA et al.   ANALYTICAL SCIENCES

Controlling the Fluorescence of Benzofuran-Modified Uracil Residues in Oligonucleotides by Triple-Helix Formation

(2014) Takashi Kanamori et al.   CHEMBIOCHEM

Existence and consequences of G-quadruplex structures in DNA

(2014) Pierre Murat et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Isomorphic Emissive GTP Surrogate Facilitates Initiation and Elongation of in Vitro Transcription Reactions

(2014) Lisa S. McCoy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A base-modified PNA–graphene oxide platform as a turn-on fluorescence sensor for the detection of human telomeric repeats

(2014) Pramod M. Sabale et al.   Nanoscale

Thioflavin T as a fluorescence light-up probe for G4 formation

(2014) Amandine Renaud de la Faverie et al.   NUCLEIC ACIDS RESEARCH

Quantification of plasma HIV RNA using chemically engineered peptide nucleic acids

(2014) Chao Zhao et al.   Nature Communications

Enzymatic Interconversion of Isomorphic Fluorescent Nucleosides: Adenosine Deaminase Transforms an Adenosine Analogue into an Inosine Analogue

(2013) Renatus W. Sinkeldam et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Artificial Genetic Sets Composed of Size-Expanded Base Pairs

(2013) Malte Winnacker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorescent-Ligand-Mediated Screening of G-Quadruplex Structures Using a DNA Microarray

(2013) Keisuke Iida et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Heavy Atom Containing Fluorescent Ribonucleoside Analog Probe for the Fluorescence Detection of RNA-Ligand Binding

(2013) Maroti G. Pawar et al.   BIOCONJUGATE CHEMISTRY

Strand Invasion of DNA Quadruplexes by PNA: Comparison of Homologous and Complementary Hybridization

(2013) Anisha Gupta et al.   CHEMBIOCHEM

Fluorescent Probes for G-Quadruplex Structures

(2013) Balayeshwanth R. Vummidi et al.   CHEMBIOCHEM

2,4-Diamino-6,7-dimethylpteridine as a fluorescent ligand for binding and sensing an orphan cytosine in RNA duplexes

(2013) Yusuke Sato et al.   CHEMICAL COMMUNICATIONS

Fluorescence modification of the AAAA (4A) loop: toward a probe of the structural dynamics of the i-motif of the retinoblastoma gene

(2013) Jung Woo Park et al.   CHEMICAL COMMUNICATIONS

A Fluorescent Guanosine Dinucleoside as a Selective Switch-On Sensor forc-mycG-Quadruplex DNA with Potent Anticancer Activities

(2013) Y. Pavan Kumar et al.   CHEMISTRY-A EUROPEAN JOURNAL

Fluorescent Nucleoside Analogs: Probes for Investigating Nucleic Acid Structure and Function

(2013) Arun A. Tanpure et al.   ISRAEL JOURNAL OF CHEMISTRY

Oligodeoxynucleotides Containing Multiple Thiophene-Modified Isomorphic Fluorescent Nucleosides

(2013) Mary S. Noé et al.   JOURNAL OF ORGANIC CHEMISTRY

Environment-Responsive Fluorescent Nucleoside Analogue Probe for Studying Oligonucleotide Dynamics in a Model Cell-like Compartment

(2013) Maroti G. Pawar et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Detection of G-quadruplex DNA in mammalian cells

(2013) A. Henderson et al.   NUCLEIC ACIDS RESEARCH

In-cell optical imaging of exogenous G-quadruplex DNA by fluorogenic ligands

(2013) Ting-Yuan Tseng et al.   NUCLEIC ACIDS RESEARCH

An Acetylene-Bridged 6,8-Purine Dimer as a Fluorescent Switch-On Probe for Parallel G-Quadruplexes

(2012) Mehran Nikan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Triple-Helical Recognition of RNA Using 2-Aminopyridine-Modified PNA at Physiologically Relevant Conditions

(2012) Thomas Zengeya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorescent Peptide–PNA Chimeras for Imaging Monoamine Oxidase A mRNA in Neuronal Cells

(2012) Dalip Sethi et al.   BIOCONJUGATE CHEMISTRY

Synthesis and Photophysical Characterisation of a Fluorescent Nucleoside Analogue that Signals the Presence of an Abasic Site in RNA

(2012) Arun A. Tanpure et al.   CHEMBIOCHEM

A Universal Nucleoside with Strong Two-Band Switchable Fluorescence and Sensitivity to the Environment for Investigating DNA Interactions

(2012) Dmytro Dziuba et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thioflavin T as an Efficient Inducer and Selective Fluorescent Sensor for the Human Telomeric G-Quadruplex DNA

(2012) Jyotirmayee Mohanty et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A FRET-based screening assay for nucleic acid ligands

(2012) Daniel Renčiuk et al.   METHODS

Detection of Endogenous K-ras mRNA in Living Cells at a Single Base Resolution by a PNA Molecular Beacon

(2012) Yossi Kam et al.   MOLECULAR PHARMACEUTICS

8-Vinylguanine Nucleo Amino Acid: A Fluorescent PNA Building Block

(2012) Stefan Müllar et al.   ORGANIC LETTERS

Labelling of nucleosides and oligonucleotides by solvatochromic 4-aminophthalimide fluorophore for studying DNA–protein interactions

(2012) Jan Riedl et al.   Chemical Science

Novel Modifications in RNA

(2011) Kelly Phelps et al.   ACS Chemical Biology

8-Vinyl-2′-deoxyguanosine as a Fluorescent 2′-Deoxyguanosine Mimic for Investigating DNA Hybridization and Topology

(2011) André Nadler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorescence Imaging of Influenza H1N1 mRNA in Living Infected Cells Using Single-Chromophore FIT-PNA

(2011) Susann Kummer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Label-free fluorescence detection of the depurination activity of ribosome inactivating protein toxins

(2011) Arun A. Tanpure et al.   CHEMICAL COMMUNICATIONS

The application of DNA and RNA G-quadruplexes to therapeutic medicines

(2011) Gavin W. Collie et al.   CHEMICAL SOCIETY REVIEWS

A Microenvironment-Sensitive Fluorescent Pyrimidine Ribonucleoside Analogue: Synthesis, Enzymatic Incorporation, and Fluorescence Detection of a DNA Abasic Site

(2011) Arun A. Tanpure et al.   CHEMISTRY-A EUROPEAN JOURNAL

5-(Pyren-1-yl)uracil as a Base-Discriminating Fluorescent Nucleobase in Pyrrolidinyl Peptide Nucleic Acids

(2011) Chalothorn Boonlua et al.   Chemistry-An Asian Journal

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

(2011) Shankar Balasubramanian et al.   NATURE REVIEWS DRUG DISCOVERY

Highly fluorescent guanosine mimics for folding and energy transfer studies

(2011) Anaëlle Dumas et al.   NUCLEIC ACIDS RESEARCH

Chemical structure requirements and cellular targeting of microRNA-122 by peptide nucleic acids anti-miRs

(2011) Adrian G. Torres et al.   NUCLEIC ACIDS RESEARCH

Synthesis and oligomerization of Fmoc/Boc-protected PNA monomers of 2,6-diaminopurine, 2-aminopurine and thymine

(2011) André H. St. Amant et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis, Photophysical Characterization, and Enzymatic Incorporation of a Microenvironment-Sensitive Fluorescent Uridine Analog

(2011) Maroti G. Pawar et al.   ORGANIC LETTERS

Fluorescent Analogs of Biomolecular Building Blocks: Design, Properties, and Applications

(2010) Renatus W. Sinkeldam et al.   CHEMICAL REVIEWS

Peptide Nucleic Acids (PNA) in Chemical Biology and Drug Discovery

(2010) Peter E. Nielsen   CHEMISTRY & BIODIVERSITY

Emissive Nucleosides as Molecular Rotors

(2010) Renatus W. Sinkeldam et al.   CHEMPHYSCHEM

Competition between Redlich–Kister and improved Herráez equations of correlation viscosities in 1,4-dioxane +water binary mixtures at different temperatures

(2010) N. Ouerfelli et al.   PHYSICS AND CHEMISTRY OF LIQUIDS

Telomeric repeat-containing RNA structure in living cells

(2010) Y. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluorescent nucleic acid base analogues

(2010) L. Marcus Wilhelmsson   QUARTERLY REVIEWS OF BIOPHYSICS

Characterization of a K+-Induced Conformational Switch in a Human Telomeric DNA Oligonucleotide Using 2-Aminopurine Fluorescence

(2009) Robert D. Gray et al.   BIOCHEMISTRY

Signal-Off and Signal-On Design for a Label-Free Aptasensor Based on Target-Induced Self-Assembly and Abasic-Site-Binding Ligands

(2009) Zhiai Xu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Nucleic Acid Base Analog FRET-Pair Facilitating Detailed Structural Measurements in Nucleic Acid Containing Systems

(2009) Karl Börjesson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Highly Emissive Fluorescent Nucleoside that Signals the Activity of Toxic Ribosome-Inactivating Proteins

(2008) Seergazhi G. Srivatsan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Single base interrogation by a fluorescent nucleotide: each of the four DNA bases identified by fluorescence spectroscopy

(2008) Pavol Cekan et al.   CHEMICAL COMMUNICATIONS

Detection of an abasic site in RNA with stem-loop DNA beacons: Application to an activity assay for Ricin Toxin A-Chain

(2008) Setu Roday et al.  

Comparative analysis of depurination catalyzed by ricin A-chain on synthetic 32mer and 25mer oligoribonucleotides mimicking the sarcin/ricin domain of the rat 28S rRNA and E. coli 23S rRNA

(2008) Qing-Qiao Tan et al.   JOURNAL OF BIOTECHNOLOGY

Fluorescence and Hybridization Properties of Peptide Nucleic Acid Containing a Substituted Phenylpyrrolocytosine Designed to Engage Guanine with an Additional H-Bond

(2008) Filip Wojciechowski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY