The right place at the right time: Aurora B kinase localization to centromeres and kinetochores

Aurora B kinase is recruited to multiple discrete kinetochore and centromere regions in human cells

(2020) Amanda J. Broad et al.   JOURNAL OF CELL BIOLOGY

Untangling the contribution of Haspin and Bub1 to Aurora B function during mitosis

(2020) Michael A. Hadders et al.   JOURNAL OF CELL BIOLOGY

Ensemble-Level Organization of Human Kinetochores and Evidence for Distinct Tension and Attachment Sensors

(2020) Emanuele Roscioli et al.   Cell Reports

The binding of Borealin to microtubules underlies a tension independent kinetochore-microtubule error correction pathway

(2019) Prasad Trivedi et al.   Nature Communications

Aurora B-INCENP Localization at Centromeres/Inner Kinetochores Is Required for Chromosome Bi-orientation in Budding Yeast

(2019) Luis J. García-Rodríguez et al.   CURRENT BIOLOGY

The COMA complex interacts with Cse4 and positions Sli15/Ipl1 at the budding yeast inner kinetochore

(2019) Josef Fischböck-Halwachs et al.   eLife

Correcting aberrant kinetochore microtubule attachments: a hidden regulation of Aurora B on microtubules

(2019) Hironori Funabiki   CURRENT OPINION IN CELL BIOLOGY

Enrichment of Aurora B kinase at the inner kinetochore controls outer kinetochore assembly

(2019) Mary Kate Bonner et al.   JOURNAL OF CELL BIOLOGY

Centromere-localized Aurora B kinase is required for the fidelity of chromosome segregation

(2019) Cai Liang et al.   JOURNAL OF CELL BIOLOGY

Complete microtubule–kinetochore occupancy favours the segregation of merotelic attachments

(2018) Damian Dudka et al.   Nature Communications

Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments

(2018) Tae Yeon Yoo et al.   eLife

The depolymerase activity of MCAK shows a graded response to Aurora B kinase phosphorylation through allosteric regulation

(2018) Toni McHugh et al.   JOURNAL OF CELL SCIENCE

Multiple phosphorylations control recruitment of the KMN network onto kinetochores

(2018) Masatoshi Hara et al.   NATURE CELL BIOLOGY

Dual recognition of chromatin and microtubules by INCENP is important for mitotic progression

(2017) Michael S. Wheelock et al.   JOURNAL OF CELL BIOLOGY

An engineered minimal chromosomal passenger complex reveals a role for INCENP/Sli15 spindle association in chromosome biorientation

(2017) Sarah Fink et al.   JOURNAL OF CELL BIOLOGY

Phosphorylation of CENP-C by Aurora B facilitates kinetochore attachment error correction in mitosis

(2017) Xing Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inner centromere localization of the CPC maintains centromere cohesion and allows mitotic checkpoint silencing

(2017) Rutger C. C. Hengeveld et al.   Nature Communications

Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells

(2017) Roshan L. Shrestha et al.   Nature Communications

Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores

(2016) Arsen Petrovic et al.   CELL

Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly

(2016) Yoana N. Dimitrova et al.   CELL

Attachment issues: kinetochore transformations and spindle checkpoint silencing

(2016) Banafsheh Etemad et al.   CURRENT OPINION IN CELL BIOLOGY

Ubiquitin Receptor Protein UBASH3B Drives Aurora B Recruitment to Mitotic Microtubules

(2016) Ksenia Krupina et al.   DEVELOPMENTAL CELL

Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524

(2016) Anna P Baron et al.   eLife

Distinct Organization and Regulation of the Outer Kinetochore KMN Network Downstream of CENP-C and CENP-T

(2015) Florencia Rago et al.   CURRENT BIOLOGY

The Inner Centromere Protein (INCENP) Coil Is a Single α-Helix (SAH) Domain That Binds Directly to Microtubules and Is Important for Chromosome Passenger Complex (CPC) Localization and Function in Mitosis

(2015) Kumiko Samejima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at human mitotic kinetochores

(2015) Soonjoung Kim et al.   JOURNAL OF CELL BIOLOGY

Basic mechanism for biorientation of mitotic chromosomes is provided by the kinetochore geometry and indiscriminate turnover of kinetochore microtubules

(2015) Anatoly V. Zaytsev et al.   MOLECULAR BIOLOGY OF THE CELL

Mitotic Transcription Installs Sgo1 at Centromeres to Coordinate Chromosome Segregation

(2015) Hong Liu et al.   MOLECULAR CELL

Stable kinetochore–microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells

(2015) Eric C. Tauchman et al.   Nature Communications

Kinetochore–microtubule attachment is sufficient to satisfy the human spindle assembly checkpoint

(2015) Banafsheh Etemad et al.   Nature Communications

Borealin dimerization mediates optimal CPC checkpoint function by enhancing localization to centromeres and kinetochores

(2015) Michael E. Bekier et al.   Nature Communications

The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling

(2015) Veronica Krenn et al.   Frontiers in Oncology

The Architecture of CCAN Proteins Creates a Structural Integrity to Resist Spindle Forces and Achieve Proper Intrakinetochore Stretch

(2014) Aussie Suzuki et al.   DEVELOPMENTAL CELL

Accurate phosphoregulation of kinetochore–microtubule affinity requires unconstrained molecular interactions

(2014) Anatoly V. Zaytsev et al.   JOURNAL OF CELL BIOLOGY

EB1 enables spindle microtubules to regulate centromeric recruitment of Aurora B

(2014) Budhaditya Banerjee et al.   JOURNAL OF CELL BIOLOGY

Regulation of kinetochore–microtubule attachments through homeostatic control during mitosis

(2014) Kristina M. Godek et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cell division: control of the chromosomal passenger complex in time and space

(2013) Armando van der Horst et al.   CHROMOSOMA

Phospho-H2A and Cohesin Specify Distinct Tension-Regulated Sgo1 Pools at Kinetochores and Inner Centromeres

(2013) Hong Liu et al.   CURRENT BIOLOGY

The Aurora B Kinase Promotes Inner and Outer Kinetochore Interactions in Budding Yeast

(2013) B. Akiyoshi et al.   GENETICS

KNL1 facilitates phosphorylation of outer kinetochore proteins by promoting Aurora B kinase activity

(2013) Gina V. Caldas et al.   JOURNAL OF CELL BIOLOGY

Tension sensing by Aurora B kinase is independent of survivin-based centromere localization

(2013) Christopher S. Campbell et al.   NATURE

Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation

(2012) Fangwei Wang et al.   JOURNAL OF CELL BIOLOGY

The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis

(2012) Mar Carmena et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Positive Feedback Loop Involving Haspin and Aurora B Promotes CPC Accumulation at Centromeres in Mitosis

(2011) Fangwei Wang et al.   CURRENT BIOLOGY

Structural organization of the kinetochore–microtubule interface

(2011) Jennifer G. DeLuca et al.   CURRENT OPINION IN CELL BIOLOGY

Phosphorylation at serine 331 is required for Aurora B activation

(2011) Eleni Petsalaki et al.   JOURNAL OF CELL BIOLOGY

Aurora B dynamics at centromeres create a diffusion-based phosphorylation gradient

(2011) Enxiu Wang et al.   JOURNAL OF CELL BIOLOGY

Temporal changes in Hec1 phosphorylation control kinetochore-microtubule attachment stability during mitosis

(2011) K. F. DeLuca et al.   JOURNAL OF CELL SCIENCE

Examining the dynamics of chromosomal passenger complex (CPC)-dependent phosphorylation during cell division

(2011) L. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of mammalian Sgo2 by Aurora B recruits PP2A and MCAK to centromeres

(2010) Y. Tanno et al.   GENES & DEVELOPMENT

Sds22 regulates aurora B activity and microtubule–kinetochore interactions at mitosis

(2010) Markus Posch et al.   JOURNAL OF CELL BIOLOGY

Epigenetic centromere specification directs aurora B accumulation but is insufficient to efficiently correct mitotic errors

(2010) Emily A. Bassett et al.   JOURNAL OF CELL BIOLOGY

Aurora B Phosphorylates Spatially Distinct Targets to Differentially Regulate the Kinetochore-Microtubule Interface

(2010) Julie P.I. Welburn et al.   MOLECULAR CELL

Phosphorylation of the CPC by Cdk1 promotes chromosome bi-orientation

(2010) Tatsuya Tsukahara et al.   NATURE

Two Histone Marks Establish the Inner Centromere and Chromosome Bi-Orientation

(2010) Yuya Yamagishi et al.   SCIENCE

Survivin Reads Phosphorylated Histone H3 Threonine 3 to Activate the Mitotic Kinase Aurora B

(2010) Alexander E. Kelly et al.   SCIENCE

Histone H3 Thr-3 Phosphorylation by Haspin Positions Aurora B at Centromeres in Mitosis

(2010) Fangwei Wang et al.   SCIENCE

Sensing centromere tension: Aurora B and the regulation of kinetochore function

(2010) Michael A. Lampson et al.   TRENDS IN CELL BIOLOGY

Deviant Kinetochore Microtubule Dynamics Underlie Chromosomal Instability

(2009) Samuel F. Bakhoum et al.   CURRENT BIOLOGY

The life and miracles of kinetochores

(2009) Stefano Santaguida et al.   EMBO JOURNAL

Kinetochore stretching inactivates the spindle assembly checkpoint

(2009) Kazuhiko S.K. Uchida et al.   JOURNAL OF CELL BIOLOGY

Intrakinetochore stretch is associated with changes in kinetochore phosphorylation and spindle assembly checkpoint activity

(2009) Thomas J. Maresca et al.   JOURNAL OF CELL BIOLOGY

Sensing Chromosome Bi-Orientation by Spatial Separation of Aurora B Kinase from Kinetochore Substrates

(2009) D. Liu et al.   SCIENCE

Phosphorylation of H2A by Bub1 Prevents Chromosomal Instability Through Localizing Shugoshin

(2009) S. A. Kawashima et al.   SCIENCE

Phosphorylation of HsMis13 by Aurora B Kinase Is Essential for Assembly of Functional Kinetochore

(2008) Yong Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line

(2008) Zuojun Yue et al.   JOURNAL OF CELL BIOLOGY

Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient

(2008) Brian G. Fuller et al.   NATURE

Genome stability is ensured by temporal control of kinetochore–microtubule dynamics

(2008) Samuel F. Bakhoum et al.   NATURE CELL BIOLOGY

Centromeric Aurora-B Activation Requires TD-60, Microtubules, and Substrate Priming Phosphorylation

(2008) S. E. Rosasco-Nitcher et al.   SCIENCE