Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments

Aurora A kinase phosphorylates Hec1 to regulate metaphase kinetochore–microtubule dynamics

(2017) Keith F. DeLuca et al.   JOURNAL OF CELL BIOLOGY

Developing and Testing a Bayesian Analysis of Fluorescence Lifetime Measurements

(2017) Bryan Kaye et al.   PLoS One

Robust Bayesian Fluorescence Lifetime Estimation, Decay Model Selection and Instrument Response Determination for Low-Intensity FLIM Imaging

(2016) Mark I. Rowley et al.   PLoS One

Bistability of a coupled Aurora B kinase-phosphatase system in cell division

(2016) Anatoly V Zaytsev et al.   eLife

Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins

(2015) Rui Zhang et al.   CELL

Probing microtubule polymerisation state at single kinetochores during metaphase chromosome motion

(2015) J. W. Armond et al.   JOURNAL OF CELL SCIENCE

Multisite phosphorylation of the NDC80 complex gradually tunes its microtubule-binding affinity

(2015) Anatoly V. Zaytsev et al.   MOLECULAR BIOLOGY OF THE CELL

Short- and long-term effects of chromosome mis-segregation and aneuploidy

(2015) Stefano Santaguida et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stable kinetochore–microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells

(2015) Eric C. Tauchman et al.   Nature Communications

A quantitative description of Ndc80 complex linkage to human kinetochores

(2015) Aussie Suzuki et al.   Nature Communications

The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling

(2015) Veronica Krenn et al.   Frontiers in Oncology

Accurate phosphoregulation of kinetochore–microtubule affinity requires unconstrained molecular interactions

(2014) Anatoly V. Zaytsev et al.   JOURNAL OF CELL BIOLOGY

Effect of Small-Molecule Modification on Single-Cell Pharmacokinetics of PARP Inhibitors

(2014) G. M. Thurber et al.   MOLECULAR CANCER THERAPEUTICS

Regulation of kinetochore–microtubule attachments through homeostatic control during mitosis

(2014) Kristina M. Godek et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tension sensing by Aurora B kinase is independent of survivin-based centromere localization

(2013) Christopher S. Campbell et al.   NATURE

Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation

(2013) Lilian Kabeche et al.   NATURE

A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum

(2013) Nathan C Shaner et al.   NATURE METHODS

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

A Pareto-Optimal Refinement Method for Protein Design Scaffolds

(2013) Lucas Gregorio Nivón et al.   PLoS One

Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues

(2013) R. K. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation

(2012) Fangwei Wang et al.   JOURNAL OF CELL BIOLOGY

The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis

(2012) Mar Carmena et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Deformations Within Moving Kinetochores Reveal Different Sites of Active and Passive Force Generation

(2012) S. Dumont et al.   SCIENCE

Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%

(2012) Joachim Goedhart et al.   Nature Communications

The Spatial Arrangement of Chromosomes during Prometaphase Facilitates Spindle Assembly

(2011) Valentin Magidson et al.   CELL

Feedback Control in Sensing Chromosome Biorientation by the Aurora B Kinase

(2011) Kevan J. Salimian et al.   CURRENT BIOLOGY

Temporal changes in Hec1 phosphorylation control kinetochore-microtubule attachment stability during mitosis

(2011) K. F. DeLuca et al.   JOURNAL OF CELL SCIENCE

Fluorescence Lifetime Measurements and Biological Imaging

(2010) Mikhail Y. Berezin et al.   CHEMICAL REVIEWS

Tumoral and tissue-specific expression of the major human β-tubulin isotypes

(2010) Luis J. Leandro-García et al.   Cytoskeleton

Gradient of Increasing Aurora B Kinase Activity Is Required for Cells to Execute Mitosis

(2010) Zhenjie Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sds22 regulates aurora B activity and microtubule–kinetochore interactions at mitosis

(2010) Markus Posch et al.   JOURNAL OF CELL BIOLOGY

Tension directly stabilizes reconstituted kinetochore-microtubule attachments

(2010) Bungo Akiyoshi et al.   NATURE

The Ndc80 kinetochore complex forms oligomeric arrays along microtubules

(2010) Gregory M. Alushin et al.   NATURE

Fluorescent labeling of tetracysteine-tagged proteins in intact cells

(2010) Carsten Hoffmann et al.   Nature Protocols

Sensing centromere tension: Aurora B and the regulation of kinetochore function

(2010) Michael A. Lampson et al.   TRENDS IN CELL BIOLOGY

Sub-angstrom accuracy in protein loop reconstruction by robotics-inspired conformational sampling

(2009) Daniel J Mandell et al.   NATURE METHODS

Microrheology of Microtubule Solutions and Actin-Microtubule Composite Networks

(2009) Vincent Pelletier et al.   PHYSICAL REVIEW LETTERS

Sensing Chromosome Bi-Orientation by Spatial Separation of Aurora B Kinase from Kinetochore Substrates

(2009) D. Liu et al.   SCIENCE

Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex

(2008) Claudio Ciferri et al.   CELL

Kinetochore-Microtubule Attachment Relies on the Disordered N-Terminal Tail Domain of Hec1

(2008) Geoffrey J. Guimaraes et al.   CURRENT BIOLOGY

ABSINTH: A new continuum solvation model for simulations of polypeptides in aqueous solutions

(2008) Andreas Vitalis et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient

(2008) Brian G. Fuller et al.   NATURE

Centromeric Aurora-B Activation Requires TD-60, Microtubules, and Substrate Priming Phosphorylation

(2008) S. E. Rosasco-Nitcher et al.   SCIENCE

Precise Measurement of Diffusion Coefficients using Scanning Fluorescence Correlation Spectroscopy

(2007) Zdeněk Petrášek et al.   BIOPHYSICAL JOURNAL

Molecular architecture of the kinetochore–microtubule interface

(2007) Iain M. Cheeseman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY