Kinetochore–microtubule attachment is sufficient to satisfy the human spindle assembly checkpoint

Multisite phosphorylation of the NDC80 complex gradually tunes its microtubule-binding affinity

(2015) Anatoly V. Zaytsev et al.   MOLECULAR BIOLOGY OF THE CELL

The kinetochore encodes a mechanical switch to disrupt spindle assembly checkpoint signalling

(2015) Pavithra Aravamudhan et al.   NATURE CELL BIOLOGY

Competition between MPS1 and microtubules at kinetochores regulates spindle checkpoint signaling

(2015) Y. Hiruma et al.   SCIENCE

Kinetochore attachment sensed by competitive Mps1 and microtubule binding to Ndc80C

(2015) Z. Ji et al.   SCIENCE

Joined at the hip: kinetochores, microtubules, and spindle assembly checkpoint signaling

(2015) Carlos Sacristan et al.   TRENDS IN CELL BIOLOGY

PP2A-B56 opposes Mps1 phosphorylation of Knl1 and thereby promotes spindle assembly checkpoint silencing

(2014) Antonio Espert et al.   JOURNAL OF CELL BIOLOGY

Accurate phosphoregulation of kinetochore–microtubule affinity requires unconstrained molecular interactions

(2014) Anatoly V. Zaytsev et al.   JOURNAL OF CELL BIOLOGY

Negative feedback at kinetochores underlies a responsive spindle checkpoint signal

(2014) Wilco Nijenhuis et al.   NATURE CELL BIOLOGY

Signalling dynamics in the spindle checkpoint response

(2014) Nitobe London et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Phosphorylation of Microtubule-binding Protein Hec1 by Mitotic Kinase Aurora B Specifies Spindle Checkpoint Kinase Mps1 Signaling at the Kinetochore

(2013) Tongge Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A TPR domain–containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B

(2013) Wilco Nijenhuis et al.   JOURNAL OF CELL BIOLOGY

Arrayed BUB recruitment modules in the kinetochore scaffold KNL1 promote accurate chromosome segregation

(2013) Mathijs Vleugel et al.   JOURNAL OF CELL BIOLOGY

The spindle assembly checkpoint works like a rheostat rather than a toggle switch

(2013) Philippe Collin et al.   NATURE CELL BIOLOGY

Crosstalk Between Microtubule Attachment Complexes Ensures Accurate Chromosome Segregation

(2013) D. K. Cheerambathur et al.   SCIENCE

Evolution and Function of the Mitotic Checkpoint

(2012) Mathijs Vleugel et al.   DEVELOPMENTAL CELL

Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore

(2012) Emily A. Foley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inducible, reversible system for the rapid and complete degradation of proteins in mammalian cells

(2012) A. J. Holland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Spatial Arrangement of Chromosomes during Prometaphase Facilitates Spindle Assembly

(2011) Valentin Magidson et al.   CELL

Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction

(2011) Stefano Santaguida et al.   EMBO JOURNAL

Spindle microtubules generate tension-dependent changes in the distribution of inner kinetochore proteins

(2011) Aussie Suzuki et al.   JOURNAL OF CELL BIOLOGY

Temporal changes in Hec1 phosphorylation control kinetochore-microtubule attachment stability during mitosis

(2011) K. F. DeLuca et al.   JOURNAL OF CELL SCIENCE

The Ndc80 complex uses a tripartite attachment point to couple microtubule depolymerization to chromosome movement

(2011) John G. Tooley et al.   MOLECULAR BIOLOGY OF THE CELL

The NDC80 complex proteins Nuf2 and Hec1 make distinct contributions to kinetochore–microtubule attachment in mitosis

(2011) Lynsie J.R. Sundin et al.   MOLECULAR BIOLOGY OF THE CELL

Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis

(2011) Adrian T. Saurin et al.   Nature Communications

Kinetochore–microtubule interactions: steps towards bi-orientation

(2010) Tomoyuki U Tanaka   EMBO JOURNAL

Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells

(2010) R. Gassmann et al.   GENES & DEVELOPMENT

Spindly/CCDC99 Is Required for Efficient Chromosome Congression and Mitotic Checkpoint Regulation

(2010) Marin Barisic et al.   MOLECULAR BIOLOGY OF THE CELL

Aurora B Phosphorylates Spatially Distinct Targets to Differentially Regulate the Kinetochore-Microtubule Interface

(2010) Julie P.I. Welburn et al.   MOLECULAR CELL

Centromere tension: a divisive issue

(2010) Alexey Khodjakov et al.   NATURE CELL BIOLOGY

Chemical Genetic Inhibition of Mps1 in Stable Human Cell Lines Reveals Novel Aspects of Mps1 Function in Mitosis

(2010) Tale Sliedrecht et al.   PLoS One

Protein Architecture of the Human Kinetochore Microtubule Attachment Site

(2009) Xiaohu Wan et al.   CELL

Sister chromatid tension and the spindle assembly checkpoint

(2009) Luigi Nezi et al.   CURRENT OPINION IN CELL BIOLOGY

Kinetochore stretching inactivates the spindle assembly checkpoint

(2009) Kazuhiko S.K. Uchida et al.   JOURNAL OF CELL BIOLOGY

Intrakinetochore stretch is associated with changes in kinetochore phosphorylation and spindle assembly checkpoint activity

(2009) Thomas J. Maresca et al.   JOURNAL OF CELL BIOLOGY

Bub1 regulates chromosome segregation in a kinetochore-independent manner

(2009) Christiane Klebig et al.   JOURNAL OF CELL BIOLOGY

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex

(2008) Claudio Ciferri et al.   CELL

Kinetochore-Microtubule Attachment Relies on the Disordered N-Terminal Tail Domain of Hec1

(2008) Geoffrey J. Guimaraes et al.   CURRENT BIOLOGY

The spindle assembly checkpoint is satisfied in the absence of interkinetochore tension during mitosis with unreplicated genomes

(2008) Christopher B. O'Connell et al.   JOURNAL OF CELL BIOLOGY

Chromosomal Instability by Inefficient Mps1 Auto-Activation Due to a Weakened Mitotic Checkpoint and Lagging Chromosomes

(2008) Nannette Jelluma et al.   PLoS One