The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis

Spatiotemporal Regulation of Ipl1/Aurora Activity by Direct Cdk1 Phosphorylation

(2012) Tomasz Zimniak et al.   CURRENT BIOLOGY

Phosphodependent Recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 Kinase Maintains the Spindle Checkpoint

(2012) Lindsey A. Shepperd et al.   CURRENT BIOLOGY

Phosphoregulation of Spc105 by Mps1 and PP1 Regulates Bub1 Localization to Kinetochores

(2012) Nitobe London et al.   CURRENT BIOLOGY

Xenopus Shugoshin 2 regulates the spindle assembly pathway mediated by the chromosomal passenger complex

(2012) Teresa Rivera et al.   EMBO JOURNAL

Cell division control by the Chromosomal Passenger Complex

(2012) Maike S. van der Waal et al.   EXPERIMENTAL CELL RESEARCH

A conserved role for COMA/CENP-H/I/N kinetochore proteins in the spindle checkpoint

(2012) D. R. Matson et al.   GENES & DEVELOPMENT

Effects of phosphatase and proteasome inhibitors on Borealin phosphorylation and degradation

(2012) Dipali Date et al.   JOURNAL OF BIOCHEMISTRY

Aurora B controls kinetochore–microtubule attachments by inhibiting Ska complex–KMN network interaction

(2012) Ying Wai Chan et al.   JOURNAL OF CELL BIOLOGY

Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation

(2012) Fangwei Wang et al.   JOURNAL OF CELL BIOLOGY

A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B

(2012) Anna De Antoni et al.   JOURNAL OF CELL BIOLOGY

Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore

(2012) Julien Espeut et al.   JOURNAL OF CELL BIOLOGY

Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres

(2012) Ewa Niedzialkowska et al.   MOLECULAR BIOLOGY OF THE CELL

The RanBP2/RanGAP1∗SUMO1/Ubc9 Complex Is a Multisubunit SUMO E3 Ligase

(2012) Andreas Werner et al.   MOLECULAR CELL

Molecular control of animal cell cytokinesis

(2012) Juan Pablo Fededa et al.   NATURE CELL BIOLOGY

MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components

(2012) Yuya Yamagishi et al.   NATURE CELL BIOLOGY

ESCRT-III Governs the Aurora B-Mediated Abscission Checkpoint Through CHMP4C

(2012) J. G. Carlton et al.   SCIENCE

Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin

(2012) Jiamu Du et al.   STRUCTURE

The chromosomal passenger complex controls the function of endosomal sorting complex required for transport-III Snf7 proteins during cytokinesis

(2012) L. Capalbo et al.   Open Biology

The Chromosomal Passenger Complex Activates Polo Kinase at Centromeres

(2012) Mar Carmena et al.   PLOS BIOLOGY

Threonine 48 in the BIR domain of survivin is critical to its mitotic and anti-apoptotic activities and can be phosphorylated by CK2 in vitro

(2011) Rachel M.A. Barrett et al.   CELL CYCLE

Localized Aurora B activity spatially controls non-kinetochore microtubules during spindle assembly

(2011) Marvin E. Tanenbaum et al.   CHROMOSOMA

A Complex of Kif18b and MCAK Promotes Microtubule Depolymerization and Is Negatively Regulated by Aurora Kinases

(2011) Marvin E. Tanenbaum et al.   CURRENT BIOLOGY

PP1/Repo-Man Dephosphorylates Mitotic Histone H3 at T3 and Regulates Chromosomal Aurora B Targeting

(2011) Junbin Qian et al.   CURRENT BIOLOGY

Feedback Control in Sensing Chromosome Biorientation by the Aurora B Kinase

(2011) Kevan J. Salimian et al.   CURRENT BIOLOGY

A Positive Feedback Loop Involving Haspin and Aurora B Promotes CPC Accumulation at Centromeres in Mitosis

(2011) Fangwei Wang et al.   CURRENT BIOLOGY

KNL1/Spc105 Recruits PP1 to Silence the Spindle Assembly Checkpoint

(2011) Jessica S. Rosenberg et al.   CURRENT BIOLOGY

Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development

(2011) G. Fernandez-Miranda et al.   DEVELOPMENT

Aurora B Regulates Formin mDia3 in Achieving Metaphase Chromosome Alignment

(2011) Lina Cheng et al.   DEVELOPMENTAL CELL

Spindle Checkpoint Silencing Requires Association of PP1 to Both Spc7 and Kinesin-8 Motors

(2011) John C. Meadows et al.   DEVELOPMENTAL CELL

Repo-Man Coordinates Chromosomal Reorganization with Nuclear Envelope Reassembly during Mitotic Exit

(2011) Paola Vagnarelli et al.   DEVELOPMENTAL CELL

Targeting of the RhoGEF Ect2 to the Equatorial Membrane Controls Cleavage Furrow Formation during Cytokinesis

(2011) Kuan-Chung Su et al.   DEVELOPMENTAL CELL

Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction

(2011) Stefano Santaguida et al.   EMBO JOURNAL

Mitotic kinase Aurora-B is regulated by SUMO-2/3 conjugation/deconjugation during mitosis

(2011) Reiko Ban et al.   GENES TO CELLS

Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC–spindle interaction to ensure proper microtubule dynamics

(2011) Yuko Nakajima et al.   JOURNAL OF CELL BIOLOGY

The chromosomal passenger complex and centralspindlin independently contribute to contractile ring assembly

(2011) Lindsay Lewellyn et al.   JOURNAL OF CELL BIOLOGY

Phosphorylation at serine 331 is required for Aurora B activation

(2011) Eleni Petsalaki et al.   JOURNAL OF CELL BIOLOGY

Aurora B dynamics at centromeres create a diffusion-based phosphorylation gradient

(2011) Enxiu Wang et al.   JOURNAL OF CELL BIOLOGY

Cdc48/p97-Ufd1-Npl4 antagonizes Aurora B during chromosome segregation in HeLa cells

(2011) G. Dobrynin et al.   JOURNAL OF CELL SCIENCE

Temporal changes in Hec1 phosphorylation control kinetochore-microtubule attachment stability during mitosis

(2011) K. F. DeLuca et al.   JOURNAL OF CELL SCIENCE

Different roles for Aurora B in condensin targeting during mitosis and meiosis

(2011) K. S. Collette et al.   JOURNAL OF CELL SCIENCE

Condensin phosphorylated by the Aurora-B-like kinase Ark1 is continuously required until telophase in a mode distinct from Top2

(2011) N. Nakazawa et al.   JOURNAL OF CELL SCIENCE

Zwint-1 is a novel Aurora B substrate required for the assembly of a dynein-binding platform on kinetochores

(2011) James M. Kasuboski et al.   MOLECULAR BIOLOGY OF THE CELL

The Ndc80 complex uses a tripartite attachment point to couple microtubule depolymerization to chromosome movement

(2011) John G. Tooley et al.   MOLECULAR BIOLOGY OF THE CELL

Role of Survivin in cytokinesis revealed by a separation-of-function allele

(2011) Edith Szafer-Glusman et al.   MOLECULAR BIOLOGY OF THE CELL

Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells

(2011) Jungseog Kang et al.   MOLECULAR BIOLOGY OF THE CELL

Condensin association with histone H2A shapes mitotic chromosomes

(2011) Kenji Tada et al.   NATURE

Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase

(2011) Emily A. Foley et al.   NATURE CELL BIOLOGY

Constitutive Mad1 targeting to kinetochores uncouples checkpoint signalling from chromosome biorientation

(2011) Maria Maldonado et al.   NATURE CELL BIOLOGY

Disabling the mitotic spindle and tumor growth by targeting a cavity-induced allosteric site of survivin

(2011) A Berezov et al.   ONCOGENE

Examining the dynamics of chromosomal passenger complex (CPC)-dependent phosphorylation during cell division

(2011) L. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamics of endosomal sorting complex required for transport (ESCRT) machinery during cytokinesis and its role in abscission

(2011) N. Elia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Midzone-Based Ruler Adjusts Chromosome Compaction to Anaphase Spindle Length

(2011) G. Neurohr et al.   SCIENCE

Cortical Constriction During Abscission Involves Helices of ESCRT-III-Dependent Filaments

(2011) J. Guizetti et al.   SCIENCE

Mitotic Substrates of the Kinase Aurora with Roles in Chromatin Regulation Identified Through Quantitative Phosphoproteomics of Fission Yeast

(2011) A. Koch et al.   Science Signaling

Structural Basis for the Recognition of Phosphorylated Histone H3 by the Survivin Subunit of the Chromosomal Passenger Complex

(2011) A. Arockia Jeyaprakash et al.   STRUCTURE

Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis

(2011) Adrian T. Saurin et al.   Nature Communications

Caenorhabditis elegans TLK-1 controls cytokinesis by localizing AIR-2/Aurora B to midzone microtubules

(2010) Chan-Hsien Yeh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E

(2010) Yumi Kim et al.   CELL

Relocation of the Chromosomal Passenger Complex Prevents Mitotic Checkpoint Engagement at Anaphase

(2010) María Dolores Vázquez-Novelle et al.   CURRENT BIOLOGY

Sli15INCENP Dephosphorylation Prevents Mitotic Checkpoint Reengagement Due to Loss of Tension at Anaphase Onset

(2010) Lesia Mirchenko et al.   CURRENT BIOLOGY

Aurora B and 14-3-3 Coordinately Regulate Clustering of Centralspindlin during Cytokinesis

(2010) Max E. Douglas et al.   CURRENT BIOLOGY

Dual Detection of Chromosomes and Microtubules by the Chromosomal Passenger Complex Drives Spindle Assembly

(2010) Boo Shan Tseng et al.   DEVELOPMENTAL CELL

Phosphorylation of mammalian Sgo2 by Aurora B recruits PP2A and MCAK to centromeres

(2010) Y. Tanno et al.   GENES & DEVELOPMENT

Cooperation Between the Septins and the Actomyosin Ring and Role of a Cell-Integrity Pathway During Cell Division in Fission Yeast

(2010) J.-Q. Wu et al.   GENETICS

Liaisons between Survivin and Plk1 during Cell Division and Cell Death

(2010) Rita Colnaghi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CENP-U Cooperates with Hec1 to Orchestrate Kinetochore-Microtubule Attachment

(2010) Shasha Hua et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sds22 regulates aurora B activity and microtubule–kinetochore interactions at mitosis

(2010) Markus Posch et al.   JOURNAL OF CELL BIOLOGY

Epigenetic centromere specification directs aurora B accumulation but is insufficient to efficiently correct mitotic errors

(2010) Emily A. Bassett et al.   JOURNAL OF CELL BIOLOGY

Defects in nuclear pore assembly lead to activation of an Aurora B–mediated abscission checkpoint

(2010) Douglas R. Mackay et al.   JOURNAL OF CELL BIOLOGY

Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling

(2010) John Maciejowski et al.   JOURNAL OF CELL BIOLOGY

Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase

(2010) Dan Liu et al.   JOURNAL OF CELL BIOLOGY

Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B

(2010) Jerry F. Tien et al.   JOURNAL OF CELL BIOLOGY

Inner centromere formation requires hMis14, a trident kinetochore protein that specifically recruits HP1 to human chromosomes

(2010) Tomomi Kiyomitsu et al.   JOURNAL OF CELL BIOLOGY

Welcome to a new kind of tension: translating kinetochore mechanics into a wait-anaphase signal

(2010) Thomas J. Maresca et al.   JOURNAL OF CELL SCIENCE

SUMOylation modulates the function of Aurora-B kinase

(2010) G. Fernandez-Miranda et al.   JOURNAL OF CELL SCIENCE

Regulation of borealin by phosphorylation at serine 219

(2010) Harpreet Kaur et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Aurora B Phosphorylates Spatially Distinct Targets to Differentially Regulate the Kinetochore-Microtubule Interface

(2010) Julie P.I. Welburn et al.   MOLECULAR CELL

Phosphorylation of the CPC by Cdk1 promotes chromosome bi-orientation

(2010) Tatsuya Tsukahara et al.   NATURE

The Ndc80 kinetochore complex forms oligomeric arrays along microtubules

(2010) Gregory M. Alushin et al.   NATURE

Human POGZ modulates dissociation of HP1α from mitotic chromosome arms through Aurora B activation

(2010) Ryu-Suke Nozawa et al.   NATURE CELL BIOLOGY

Two Histone Marks Establish the Inner Centromere and Chromosome Bi-Orientation

(2010) Yuya Yamagishi et al.   SCIENCE

Survivin Reads Phosphorylated Histone H3 Threonine 3 to Activate the Mitotic Kinase Aurora B

(2010) Alexander E. Kelly et al.   SCIENCE

Histone H3 Thr-3 Phosphorylation by Haspin Positions Aurora B at Centromeres in Mitosis

(2010) Fangwei Wang et al.   SCIENCE

Sensing centromere tension: Aurora B and the regulation of kinetochore function

(2010) Michael A. Lampson et al.   TRENDS IN CELL BIOLOGY

Aurora B kinase activation requires survivin priming phosphorylation by PLK1

(2010) Youjun Chu et al.   Journal of Molecular Cell Biology

The Ndc80 Kinetochore Complex Forms Load-Bearing Attachments to Dynamic Microtubule Tips via Biased Diffusion

(2009) Andrew F. Powers et al.   CELL

Aurora B-Mediated Abscission Checkpoint Protects against Tetraploidization

(2009) Patrick Steigemann et al.   CELL

ICIS and Aurora B Coregulate the Microtubule Depolymerase Kif2a

(2009) Anne L. Knowlton et al.   CURRENT BIOLOGY

Cdk1 Negatively Regulates Midzone Localization of the Mitotic Kinesin Mklp2 and the Chromosomal Passenger Complex

(2009) Stefan Hümmer et al.   CURRENT BIOLOGY

A Novel Protein Phosphatase 1-Dependent Spindle Checkpoint Silencing Mechanism

(2009) Vincent Vanoosthuyse et al.   CURRENT BIOLOGY

Correcting aberrant kinetochore microtubule attachments: an Aurora B-centric view

(2009) Alexander E Kelly et al.   CURRENT OPINION IN CELL BIOLOGY

Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins

(2009) Mar Carmena et al.   CURRENT OPINION IN CELL BIOLOGY

The Human Kinetochore Ska1 Complex Facilitates Microtubule Depolymerization-Coupled Motility

(2009) Julie P.I. Welburn et al.   DEVELOPMENTAL CELL

Quantitative proteomic analysis of purified yeast kinetochores identifies a PP1 regulatory subunit

(2009) B. Akiyoshi et al.   GENES & DEVELOPMENT

INCENP–aurora B interactions modulate kinase activity and chromosome passenger complex localization

(2009) Zhenjie Xu et al.   JOURNAL OF CELL BIOLOGY

Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachments

(2009) Zhenye Yang et al.   JOURNAL OF CELL BIOLOGY

Kinetochore stretching inactivates the spindle assembly checkpoint

(2009) Kazuhiko S.K. Uchida et al.   JOURNAL OF CELL BIOLOGY

Visualizing histone modifications in living cells: spatiotemporal dynamics of H3 phosphorylation during interphase

(2009) Yoko Hayashi-Takanaka et al.   JOURNAL OF CELL BIOLOGY

The Cul3–KLHL21 E3 ubiquitin ligase targets Aurora B to midzone microtubules in anaphase and is required for cytokinesis

(2009) Sarah Maerki et al.   JOURNAL OF CELL BIOLOGY

The role of survivin2 in primitive hematopoiesis during zebrafish development

(2009) A C H Ma et al.   LEUKEMIA

Binding Partner Switching on Microtubules and Aurora-B in the Mitosis to Cytokinesis Transition

(2009) Nurhan Özlü et al.   MOLECULAR & CELLULAR PROTEOMICS

Nbl1p: A Borealin/Dasra/CSC-1-like Protein Essential for Aurora/Ipl1 Complex Function and Integrity in Saccharomyces cerevisiae

(2009) Yuko Nakajima et al.   MOLECULAR BIOLOGY OF THE CELL

A Link between Aurora Kinase and Clp1/Cdc14 Regulation Uncovered by the Identification of a Fission Yeast Borealin-Like Protein

(2009) K. Adam Bohnert et al.   MOLECULAR BIOLOGY OF THE CELL

Sensing Chromosome Bi-Orientation by Spatial Separation of Aurora B Kinase from Kinetochore Substrates

(2009) D. Liu et al.   SCIENCE

Phosphorylation of H2A by Bub1 Prevents Chromosomal Instability Through Localizing Shugoshin

(2009) S. A. Kawashima et al.   SCIENCE

A dominant-negative ESCRT-III protein perturbs cytokinesis and trafficking to lysosomes

(2008) Joseph D. Dukes et al.   BIOCHEMICAL JOURNAL

Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex

(2008) Claudio Ciferri et al.   CELL

Mps1 Phosphorylates Borealin to Control Aurora B Activity and Chromosome Alignment

(2008) Nannette Jelluma et al.   CELL

Kinetochore-Microtubule Attachment Relies on the Disordered N-Terminal Tail Domain of Hec1

(2008) Geoffrey J. Guimaraes et al.   CURRENT BIOLOGY

Kinetochore Attachments Require an Interaction between Unstructured Tails on Microtubules and Ndc80Hec1

(2008) Stephanie A. Miller et al.   CURRENT BIOLOGY

Phosphoregulation of MgcRacGAP in mitosis involves Aurora B and Cdk1 protein kinases and the PP2A phosphatase

(2008) Aminata Touré et al.   FEBS LETTERS

Australin: a chromosomal passenger protein required specifically forDrosophila melanogastermale meiosis

(2008) Shan Gao et al.   JOURNAL OF CELL BIOLOGY

Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly

(2008) Michael J. Emanuele et al.   JOURNAL OF CELL BIOLOGY

Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line

(2008) Zuojun Yue et al.   JOURNAL OF CELL BIOLOGY

Dissection of the essential steps for condensin accumulation at kinetochores and rDNAs during fission yeast mitosis

(2008) Norihiko Nakazawa et al.   JOURNAL OF CELL BIOLOGY

RanBP2 and SENP3 Function in a Mitotic SUMO2/3 Conjugation-Deconjugation Cycle on Borealin

(2008) Ulf R. Klein et al.   MOLECULAR BIOLOGY OF THE CELL

Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient

(2008) Brian G. Fuller et al.   NATURE

Phosphoregulation and depolymerization-driven movement of the Dam1 complex do not require ring formation

(2008) Daniel R. Gestaut et al.   NATURE CELL BIOLOGY

Centromeric Aurora-B Activation Requires TD-60, Microtubules, and Substrate Priming Phosphorylation

(2008) S. E. Rosasco-Nitcher et al.   SCIENCE

Inhibition of Rac by the GAP Activity of Centralspindlin Is Essential for Cytokinesis

(2008) J. C. Canman et al.   SCIENCE

Dual Role of Topoisomerase II in Centromere Resolution and Aurora B Activity

(2008) Paula A Coelho et al.   PLOS BIOLOGY