Modulatory effects of α7 nAChRs on the immune system and its relevance for CNS disorders

The role of inflammation in suicidal behaviour

(2015) L. Brundin et al.   ACTA PSYCHIATRICA SCANDINAVICA

The Antinociceptive and Antiinflammatory Properties of 3-furan-2-yl-N-p-tolyl-acrylamide, a Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptors in Mice

(2015) Deniz Bagdas et al.   ANESTHESIA AND ANALGESIA

Functional alpha7 nicotinic receptors are expressed on immature granule cells of the postnatal dentate gyrus

(2015) Danielle John et al.   BRAIN RESEARCH

The combination of lithium and l-Dopa/Carbidopa reduces MPTP-induced abnormal involuntary movements (AIMs) via calpain-1 inhibition in a mouse model: Relevance for Parkinson׳s disease therapy

(2015) Carol A. Lazzara et al.   BRAIN RESEARCH

High therapeutic potential of positive allosteric modulation of α7 nAChRs in a rat model of traumatic brain injury: Proof-of-concept

(2015) Joshua W. Gatson et al.   BRAIN RESEARCH BULLETIN

AQW051, a novel, potent and selective α7 nicotinic ACh receptor partial agonist: pharmacological characterization and phase I evaluation

(2015) Dominik Feuerbach et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Therapeutic Potential of α7 Nicotinic Acetylcholine Receptor (α7 nAChR) Agonists for the Treatment of the Cognitive Deficits Associated with Schizophrenia

(2015) Corinne Beinat et al.   CNS DRUGS

Targeting of α7 Nicotinic Acetylcholine Receptors in the Treatment of Schizophrenia and the Use of Auditory Sensory Gating as a Translational Biomarker

(2015) Kenji Hashimoto   CURRENT PHARMACEUTICAL DESIGN

Activation of the anti-inflammatory reflex blocks lipopolysaccharide-induced decrease in synaptic inhibition in the temporal cortex of the rat

(2015) Francisco Garcia-Oscos et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Monocyte and microglial activation in patients with mood-stabilized bipolar disorder

(2015) Joel Jakobsson et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Dementia praecox redux: A systematic review of the nicotinic receptor as a target for cognitive symptoms of schizophrenia

(2015) Arann R Rowe et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The human CHRNA7 and CHRFAM7A genes: A review of the genetics, regulation, and function

(2015) Melissa L. Sinkus et al.   NEUROPHARMACOLOGY

Activation of α7 nicotinic acetylcholine receptors increases intracellular cAMP levels via activation of AC1 in hippocampal neurons

(2015) Qing Cheng et al.   NEUROPHARMACOLOGY

Activation of α7 nicotinic acetylcholine receptors protects astrocytes against oxidative stress-induced apoptosis: Implications for Parkinson's disease

(2015) Yuan Liu et al.   NEUROPHARMACOLOGY

Genes involved in pruning and inflammation are enriched in a large mega-sample of patients affected by Schizophrenia and Bipolar Disorder and controls

(2015) Calabrò Marco et al.   PSYCHIATRY RESEARCH

Neuroinflammation and white matter pathology in schizophrenia: systematic review

(2015) Souhel Najjar et al.   SCHIZOPHRENIA RESEARCH

Nicotinic ACh receptors as therapeutic targets in CNS disorders

(2015) Kelly T. Dineley et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Smoking Is Associated with an Increased Risk of Dementia: A Meta-Analysis of Prospective Cohort Studies with Investigation of Potential Effect Modifiers

(2015) Guochao Zhong et al.   PLoS One

α7 and β2 Nicotinic Acetylcholine Receptor Subunits Form Heteromeric Receptor Complexes that Are Expressed in the Human Cortex and Display Distinct Pharmacological Properties

(2015) Morten Skøtt Thomsen et al.   PLoS One

Altered Activation of Innate Immunity Associates with White Matter Volume and Diffusion in First-Episode Psychosis

(2015) Teemu Mäntylä et al.   PLoS One

Neuroinflammation in bipolar disorder – A [11C]-(R)-PK11195 positron emission tomography study

(2014) Bartholomeus C.M. (Benno) Haarman et al.   BRAIN BEHAVIOR AND IMMUNITY

Lithium prevents parkinsonian behavioral and striatal phenotypes in an aged parkin mutant transgenic mouse model

(2014) Christopher A. Lieu et al.   BRAIN RESEARCH

Alpha7 Neuronal Nicotinic Receptor: A Pluripotent Target for Diseases of the Central Nervous System

(2014) Merouane Bencherif et al.   CNS & Neurological Disorders-Drug Targets

Targeting Brain α7 Nicotinic Acetylcholine Receptors in Alzheimer’s Disease: Rationale and Current Status

(2014) Ana Sofía Vallés et al.   CNS DRUGS

Going up in Smoke? A Review of nAChRs-based Treatment Strategies for Improving Cognition in Schizophrenia

(2014) Douglas Boggs et al.   CURRENT PHARMACEUTICAL DESIGN

α7 nicotinic acetylcholine receptors control cytochrome c release from isolated mitochondria through kinase-mediated pathways

(2014) Galyna Gergalova et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mitochondria express several nicotinic acetylcholine receptor subtypes to control various pathways of apoptosis induction

(2014) Olena Lykhmus et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Duplicated α7 Subunits Assemble and Form Functional Nicotinic Receptors with the Full-length α7

(2014) Ying Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-4-Induced Selective Clearance of Oligomeric  -Amyloid Peptide1-42 by Rat Primary Type 2 Microglia

(2014) E. Shimizu et al.   JOURNAL OF IMMUNOLOGY

Lithium Prevents and Ameliorates Experimental Autoimmune Encephalomyelitis

(2014) P. De Sarno et al.   JOURNAL OF IMMUNOLOGY

CHRFAM7A, a human-specific and partially duplicated α 7-nicotinic acetylcholine receptor gene with the potential to specify a human-specific inflammatory response to injury

(2014) Todd W. Costantini et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Microglia of Prefrontal White Matter in Suicide

(2014) Tatiana P. Schnieder et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Functional expression of α7-nicotinic acetylcholine receptors by muscle afferent neurons

(2014) James C. Baxter et al.   JOURNAL OF NEUROPHYSIOLOGY

Microglial and macrophage polarization—new prospects for brain repair

(2014) Xiaoming Hu et al.   Nature Reviews Neurology

A Randomized, Placebo-Controlled Study Investigating the Nicotinic α7 Agonist, RG3487, for Cognitive Deficits in Schizophrenia

(2014) Daniel Umbricht et al.   NEUROPSYCHOPHARMACOLOGY

AQW051, a novel and selective nicotinic acetylcholine receptor α7 partial agonist, reduces l-Dopa-induced dyskinesias and extends the duration of l-Dopa effects in parkinsonian monkeys

(2014) Thérèse Di Paolo et al.   PARKINSONISM & RELATED DISORDERS

The Experimental Autoimmune Encephalomyelitis Disease Course Is Modulated by Nicotine and Other Cigarette Smoke Components

(2014) Zhen Gao et al.   PLoS One

A New IRAK-M-Mediated Mechanism Implicated in the Anti-Inflammatory Effect of Nicotine via α7 Nicotinic Receptors in Human Macrophages

(2014) Maria C. Maldifassi et al.   PLoS One

Childhood bullying involvement predicts low-grade systemic inflammation into adulthood

(2014) W. E. Copeland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism

(2014) Simone Gupta et al.   Nature Communications

Inflammation and lithium: clues to mechanisms contributing to suicide-linked traits

(2014) E Beurel et al.   Translational Psychiatry

The Neuroimmunology of Schizophrenia

(2014) Annya M et al.   Clinical Psychopharmacology and Neuroscience

Integrated Neurobiology of Bipolar Disorder

(2014) Vladimir Maletic et al.   Frontiers in Psychiatry

Disorders and borders: Psychiatric genetics and nosology

(2013) Jordan W. Smoller   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

α7 Nicotinic Receptor Agonist Enhances Cognition in Aged 3xTg-AD Mice with Robust Plaques and Tangles

(2013) Rodrigo Medeiros et al.   AMERICAN JOURNAL OF PATHOLOGY

The Microglial α7-Acetylcholine Nicotinic Receptor Is a Key Element in Promoting Neuroprotection by Inducing Heme Oxygenase-1 via Nuclear Factor Erythroid-2-Related Factor 2

(2013) Esther Parada et al.   ANTIOXIDANTS & REDOX SIGNALING

The cholinergic anti-inflammatory pathway: A critical review

(2013) D. Martelli et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Effects of neuronal nicotinic acetylcholine receptor allosteric modulators in animal behavior studies

(2013) Anshul A. Pandya et al.   BIOCHEMICAL PHARMACOLOGY

Cytokine Alterations in Bipolar Disorder: A Meta-Analysis of 30 Studies

(2013) Amirhossein Modabbernia et al.   BIOLOGICAL PSYCHIATRY

A positive allosteric modulator of α7 nAChRs augments neuroprotective effects of endogenous nicotinic agonists in cerebral ischaemia

(2013) Bopanna I Kalappa et al.   BRITISH JOURNAL OF PHARMACOLOGY

Genome-wide gene expression in a patient with 15q13.3 homozygous microdeletion syndrome

(2013) Jean-Baptiste Le Pichon et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Increased cerebrospinal fluid interleukin-6 levels in patients with schizophrenia and those with major depressive disorder

(2013) Daimei Sasayama et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Cytokines in bipolar disorder vs. healthy control subjects: A systematic review and meta-analysis

(2013) Klaus Munkholm et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Galantamine efficacy and tolerability as an augmentative therapy in autistic children: A randomized, double-blind, placebo-controlled trial

(2013) Ali Ghaleiha et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: Implications for neuropsychiatric diseases

(2013) Hong Lin et al.   NEUROBIOLOGY OF DISEASE

A Randomized Exploratory Trial of an Alpha-7 Nicotinic Receptor Agonist (TC-5619) for Cognitive Enhancement in Schizophrenia

(2013) Jeffrey A Lieberman et al.   NEUROPSYCHOPHARMACOLOGY

Connecting inflammation with glutamate agonism in suicidality

(2013) Sophie Erhardt et al.   NEUROPSYCHOPHARMACOLOGY

Microglia during development and aging

(2013) G. Jean Harry   PHARMACOLOGY & THERAPEUTICS

Oxidative Stress and Proinflammatory Cytokines Contribute to Demyelination and Axonal Damage in a Cerebellar Culture Model of Neuroinflammation

(2013) Alessandra di Penta et al.   PLoS One

Regulated Extracellular Choline Acetyltransferase Activity— The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway

(2013) Swetha Vijayaraghavan et al.   PLoS One

A Type-II Positive Allosteric Modulator of α7 nAChRs Reduces Brain Injury and Improves Neurological Function after Focal Cerebral Ischemia in Rats

(2013) Fen Sun et al.   PLoS One

A placebo-controlled study of tropisetron added to risperidone for the treatment of negative symptoms in chronic and stable schizophrenia

(2013) Maryam Noroozian et al.   PSYCHOPHARMACOLOGY

Microglia and macrophages of the central nervous system: the contribution of microglia priming and systemic inflammation to chronic neurodegeneration

(2013) V. Hugh Perry et al.   Seminars in Immunopathology

A Comprehensive Family-Based Replication Study of Schizophrenia Genes

(2013) Karolina A. Aberg et al.   JAMA Psychiatry

Functional α7β2 nicotinic acetylcholine receptors expressed in hippocampal interneurons exhibit high sensitivity to pathological level of amyloid β peptides

(2012) Qiang Liu et al.   BMC NEUROSCIENCE

Identification of single gene deletions at 15q13.3: further evidence thatCHRNA7causes the 15q13.3 microdeletion syndrome phenotype

(2012) N Hoppman-Chaney et al.   CLINICAL GENETICS

The nicotinic acetylcholine receptor α7 in subcutaneous mature adipocytes: downregulation in human obesity and modulation by diet-induced weight loss

(2012) R Cancello et al.   INTERNATIONAL JOURNAL OF OBESITY

Can bipolar disorder be viewed as a multi-system inflammatory disease?

(2012) Marion Leboyer et al.   JOURNAL OF AFFECTIVE DISORDERS

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes

(2012) Wouter Beumer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Functional α7 Nicotinic ACh Receptors on Astrocytes in Rat Hippocampal CA1 Slices

(2012) Jian-xin Shen et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

3-[(2,4-dimethoxy)benzylidene]-anabaseine dihydrochloride protects against 6-hydroxydopamine-induced parkinsonian neurodegeneration through α7 nicotinic acetylcholine receptor stimulation in rats

(2012) Syuuichirou Suzuki et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Rate of de novo mutations and the importance of father’s age to disease risk

(2012) Augustine Kong et al.   NATURE

Will the real multiple sclerosis please stand up?

(2012) Peter K. Stys et al.   NATURE REVIEWS NEUROSCIENCE

Nicotinic ACh Receptors in the Hippocampus: Role in Excitability and Plasticity

(2012) J. L. Yakel   NICOTINE & TOBACCO RESEARCH

Nicotinic acetylcholine receptors: From basic science to therapeutics

(2012) Raymond Hurst et al.   PHARMACOLOGY & THERAPEUTICS

Lack of Modulation of Nicotinic Acetylcholine Alpha-7 Receptor Currents by Kynurenic Acid in Adult Hippocampal Interneurons

(2012) Peter Dobelis et al.   PLoS One

Non-Motor Symptoms in Patients with Parkinson’s Disease – Correlations with Inflammatory Cytokines in Serum

(2012) Daniel Lindqvist et al.   PLoS One

Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk

(2012) S. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of GSK3 by lithium, from single molecules to signaling networks

(2012) Laure Freland et al.   Frontiers in Molecular Neuroscience

Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease

(2011) H. Rheinallt Parri et al.   BIOCHEMICAL PHARMACOLOGY

Meta-Analysis of Cytokine Alterations in Schizophrenia: Clinical Status and Antipsychotic Effects

(2011) Brian J. Miller et al.   BIOLOGICAL PSYCHIATRY

Targeting the 5-HT3 receptor in the treatment of irritable bowel syndrome

(2011) Robin C Spiller   CURRENT OPINION IN PHARMACOLOGY

α7 Nicotinic receptor modulators for cognitive deficits in schizophrenia and Alzheimer's disease

(2011) Hugo Geerts   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Nicotinic acetylcholine receptor alpha7 subunit is time-dependently expressed in distinct cell types during skin wound healing in mice

(2011) Yan-Yan Fan et al.   HISTOCHEMISTRY AND CELL BIOLOGY

15q11.2–13.3 chromatin analysis reveals epigenetic regulation of CHRNA7 with deficiencies in Rett and autism brain

(2011) Dag H. Yasui et al.   HUMAN MOLECULAR GENETICS

Transcriptional Repression of the α7 Nicotinic Acetylcholine Receptor Subunit Gene (CHRNA7) by Activating Protein-2α (AP-2α)

(2011) Jessica Finlay-Schultz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α7-Cholinergic Receptor Mediates Vagal Induction of Splenic Norepinephrine

(2011) Gergely Vida et al.   JOURNAL OF IMMUNOLOGY

EphB Controls NMDA Receptor Function and Synaptic Targeting in a Subunit-Specific Manner

(2011) M. J. Nolt et al.   JOURNAL OF NEUROSCIENCE

Depression in Parkinson disease—epidemiology, mechanisms and management

(2011) Dag Aarsland et al.   Nature Reviews Neurology

EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors

(2011) Jos Prickaerts et al.   NEUROPHARMACOLOGY

Developmental neuroinflammation and schizophrenia

(2011) Urs Meyer   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice

(2011) Morgane Besson et al.   PSYCHOPHARMACOLOGY

Acetylcholine-Synthesizing T Cells Relay Neural Signals in a Vagus Nerve Circuit

(2011) M. Rosas-Ballina et al.   SCIENCE

Human Platelets Express Functional α7-Nicotinic Acetylcholine Receptors

(2010) Angelika Schedel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cholinergic systems mediate action from movement to higher consciousness

(2010) Nancy J. Woolf et al.   BEHAVIOURAL BRAIN RESEARCH

Different Interaction between the Agonist JN403 and the Competitive Antagonist Methyllycaconitine with the Human α7 Nicotinic Acetylcholine Receptor

(2010) Hugo R. Arias et al.   BIOCHEMISTRY

Mast cell activation and autism

(2010) Theoharis C. Theoharides et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Neurohormonal and inflammatory hyper-responsiveness to acute mental stress in depression☆

(2010) Ali A. Weinstein et al.   BIOLOGICAL PSYCHOLOGY

Cytokine levels in the blood may distinguish suicide attempters from depressed patients

(2010) Shorena Janelidze et al.   BRAIN BEHAVIOR AND IMMUNITY

Continuous administration of a selective α7 nicotinic partial agonist, DMXBA, improves sensory inhibition without causing tachyphylaxis or receptor upregulation in DBA/2 mice

(2010) Karen E. Stevens et al.   BRAIN RESEARCH

Delineation of 15q13.3 microdeletions

(2010) A Masurel-Paulet et al.   CLINICAL GENETICS

Unphosphorylated STAT3 modulates alpha7 nicotinic receptor signaling and cytokine production in sepsis

(2010) Geber Peña et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Galantamine-induced Amyloid-β Clearance Mediated via Stimulation of Microglial Nicotinic Acetylcholine Receptors

(2010) Kazuyuki Takata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Function of Partially Duplicated Human α7 Nicotinic Receptor SubunitCHRFAM7AGene

(2010) Ana M. de Lucas-Cerrillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two-Year Outcome of Vagus Nerve Stimulation in Treatment-Resistant Depression

(2010) Malek Bajbouj et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Expression of the α7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS

(2010) Roberta Benfante et al.   JOURNAL OF NEUROIMMUNOLOGY

Loss of  7 Nicotinic Receptors Enhances  -Amyloid Oligomer Accumulation, Exacerbating Early-Stage Cognitive Decline and Septohippocampal Pathology in a Mouse Model of Alzheimer's Disease

(2010) C. M. Hernandez et al.   JOURNAL OF NEUROSCIENCE

Neurogenetics and Pharmacology of Learning, Motivation and Cognition

(2010) Michael J Frank et al.   NEUROPSYCHOPHARMACOLOGY

GSK-3β activity and hyperdopamine-dependent behaviors

(2010) Yan-Chun Li et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Occurrence of depression and anxiety prior to Parkinson’s disease

(2010) E.L. Jacob et al.   PARKINSONISM & RELATED DISORDERS

Lithium Improves Hippocampal Neurogenesis, Neuropathology and Cognitive Functions in APP Mutant Mice

(2010) Anna Fiorentini et al.   PLoS One

Evidence for association of the non-duplicated region of CHRNA7 gene with bipolar disorder but not with Schizophrenia

(2010) Inés Ancín et al.   PSYCHIATRIC GENETICS

Citation Bias in Reported Smoking Prevalence in People with Schizophrenia

(2009) Simon Chapman et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Selective α7 nicotinic acetylcholine receptor activation regulates glycogen synthase kinase3β and decreases tau phosphorylation in vivo

(2009) Robert S. Bitner et al.   BRAIN RESEARCH

A 2-base pair deletion polymorphism in the partial duplication of the α7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia

(2009) Melissa L. Sinkus et al.   BRAIN RESEARCH

Functional α7-containing nicotinic receptors of NG2-expressing cells in the hippocampus

(2009) Mateo Vélez-Fort et al.   GLIA

Inhibitory role of cholinergic system mediated via α7 nicotinic acetylcholine receptor in LPS-induced neuro-inflammation

(2009) Ethika Tyagi et al.   Innate Immunity

Inflammation and the Phenomenology, Pathophysiology, Comorbidity, and Treatment of Bipolar Disorder

(2009) Benjamin I. Goldstein et al.   JOURNAL OF CLINICAL PSYCHIATRY

Activation of the Cholinergic Anti-Inflammatory System by Nicotine Attenuates Neuroinflammation via Suppression of Th1 and Th17 Responses

(2009) E. Nizri et al.   JOURNAL OF IMMUNOLOGY

A Novel Nicotinic Acetylcholine Receptor Subtype in Basal Forebrain Cholinergic Neurons with High Sensitivity to Amyloid Peptides

(2009) Q. Liu et al.   JOURNAL OF NEUROSCIENCE

Neuroinflammation in Schizophrenia-Related Psychosis: A PET Study

(2009) J. Doorduin et al.   JOURNAL OF NUCLEAR MEDICINE

Activation and Desensitization of Nicotinic  7-type Acetylcholine Receptors by Benzylidene Anabaseines and Nicotine

(2009) R. L. Papke et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

(2009) Etienne C Hirsch et al.   LANCET NEUROLOGY

Alpha 7 nicotinic acetylcholine receptor modulates lymphocyte activation

(2009) María José De Rosa et al.   LIFE SCIENCES

Unknown

(2009) Mauricio Rosas-Ballina et al.   MOLECULAR MEDICINE

Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients

(2009) J S Rao et al.   MOLECULAR PSYCHIATRY

Mapping of brain acetylcholinesterase alterations in Lewy body disease by PET

(2009) H. Shimada et al.   NEUROLOGY

Chronic icv oxytocin attenuates the pathological high anxiety state of selectively bred Wistar rats

(2009) D.A. Slattery et al.   NEUROPHARMACOLOGY

Functional Magnetic Resonance Imaging of Effects of a Nicotinic Agonist in Schizophrenia

(2009) Jason R Tregellas et al.   NEUROPSYCHOPHARMACOLOGY

Primary sensory neuronal expression of SLURP-1, an endogenous nicotinic acetylcholine receptor ligand

(2009) Yasuhiro Moriwaki et al.   NEUROSCIENCE RESEARCH

Low early-life social class leaves a biological residue manifested by decreased glucocorticoid and increased proinflammatory signaling

(2009) G. E. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytokines and schizophrenia: Microglia hypothesis of schizophrenia

(2009) Akira Monji et al.   PSYCHIATRY AND CLINICAL NEUROSCIENCES

Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3)

(2009) Eléonore Beurel et al.   TRENDS IN IMMUNOLOGY

Oxytocin alleviates the neuroendocrine and cytokine response to bacterial endotoxin in healthy men

(2008) Martin Clodi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Initial Phase 2 Trial of a Nicotinic Agonist in Schizophrenia

(2008) Robert Freedman et al.   AMERICAN JOURNAL OF PSYCHIATRY

Nicotine Activates and Up-Regulates Nicotinic Acetylcholine Receptors in Bronchial Epithelial Cells

(2008) Xiao Wen Fu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Elevated Inflammation Levels in Depressed Adults With a History of Childhood Maltreatment

(2008) Andrea Danese et al.   ARCHIVES OF GENERAL PSYCHIATRY

Acetylcholine regulation of synoviocyte cytokine expression by the α7 nicotinic receptor

(2008) Jean-Marc Waldburger et al.   ARTHRITIS AND RHEUMATISM

Microglia Activation in Recent-Onset Schizophrenia: A Quantitative (R)-[11C]PK11195 Positron Emission Tomography Study

(2008) Bart N. van Berckel et al.   BIOLOGICAL PSYCHIATRY

Beyond genetics: childhood affective trauma in bipolar disorder

(2008) Bruno Etain et al.   BIPOLAR DISORDERS

Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans

(2008) I Wessler et al.   BRITISH JOURNAL OF PHARMACOLOGY

Preclinical Characterization of A-582941: A Novel α7 Neuronal Nicotinic Receptor Agonist with Broad Spectrum Cognition-Enhancing Properties

(2008) Karin R. Tietje et al.   CNS Neuroscience & Therapeutics

Chronic Immune Stimulation Correlates with Reduced Phenylalanine Turnover

(2008) G. Neurauter et al.   CURRENT DRUG METABOLISM

Molecular characterization and localization of the RIC-3 protein, an effector of nicotinic acetylcholine receptor expression

(2008) Francisco Castelán et al.   JOURNAL OF NEUROCHEMISTRY

Basic and Clinical Aspects of Non-neuronal Acetylcholine: Biological and Clinical Significance of Non-canonical Ligands of Epithelial Nicotinic Acetylcholine Receptors

(2008) Sergei A. Grando   JOURNAL OF PHARMACOLOGICAL SCIENCES

EphB Receptors Co-Distribute with a Nicotinic Receptor Subtype and Regulate Nicotinic Downstream Signaling in Neurons

(2008) Zhaoping Liu et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Unknown

(2008) William Parrish et al.   MOLECULAR MEDICINE

The selective nicotinic acetylcholine receptor α7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain

(2008) Dominik Feuerbach et al.   NEUROPHARMACOLOGY

Inflammation and oxidative stress in vertebrate host-parasite systems

(2008) G. Sorci et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation

(2007) W J Jonge et al.   BRITISH JOURNAL OF PHARMACOLOGY

Immunological aspects in the neurobiology of suicide: Elevated microglial density in schizophrenia and depression is associated with suicide

(2006) Johann Steiner et al.   JOURNAL OF PSYCHIATRIC RESEARCH