The Microglial α7-Acetylcholine Nicotinic Receptor Is a Key Element in Promoting Neuroprotection by Inducing Heme Oxygenase-1 via Nuclear Factor Erythroid-2-Related Factor 2

The Transcription Factor Nrf2 Is a Therapeutic Target against Brain Inflammation

(2014) N. G. Innamorato et al.   JOURNAL OF IMMUNOLOGY

Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity

(2011) Vittorio Calabrese et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

α7 Nicotinic acetylcholine receptor agonist GTS-21 attenuates ventilator-induced tumour necrosis factor-α production and lung injury

(2011) M. Kox et al.   BRITISH JOURNAL OF ANAESTHESIA

Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation

(2011) Sang-Ho Choi et al.   JOURNAL OF NEUROCHEMISTRY

Galantamine elicits neuroprotection by inhibiting iNOS, NADPH oxidase and ROS in hippocampal slices stressed with anoxia/reoxygenation

(2011) J. Egea et al.   NEUROPHARMACOLOGY

α7 Nicotinic Acetylcholine Receptor Agonist PNU-282987 Attenuates Early Brain Injury in a Perforation Model of Subarachnoid Hemorrhage in Rats

(2011) Kamil Duris et al.   STROKE

α7 Nicotinic Acetylcholine Receptor Agonism Confers Neuroprotection Through GSK-3β Inhibition in a Mouse Model of Intracerebral Hemorrhage

(2011) Paul R. Krafft et al.   STROKE

Assessment of Motor Balance and Coordination in Mice using the Balance Beam

(2011) Tinh N. Luong et al.   Jove-Journal of Visualized Experiments

Mechanisms of Cell Protection by Heme Oxygenase-1

(2010) Raffaella Gozzelino et al.   Annual Review of Pharmacology and Toxicology

Stimulation of Alpha7 Nicotinic Acetylcholine Receptor by Nicotine Attenuates Inflammatory Response in Macrophages and Improves Survival in Experimental Model of Sepsis Through Heme Oxygenase-1 Induction

(2010) Konstantin Tsoyi et al.   ANTIOXIDANTS & REDOX SIGNALING

Activation of α7 nicotinic acetylcholine receptors ameliorates indomethacin-induced small intestinal ulceration in mice

(2010) Ryoji Kawahara et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Poststress treatment with PNU282987 can rescue SH-SY5Y cells undergoing apoptosis via α7 nicotinic receptors linked to a Jak2/Akt/HO-1 signaling pathway

(2010) Esther Parada et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

(2010) Rong Jin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Reperfusion and Neurovascular Dysfunction in Stroke: from Basic Mechanisms to Potential Strategies for Neuroprotection

(2010) Joo Eun Jung et al.   MOLECULAR NEUROBIOLOGY

Human Microglia Transplanted in Rat Focal Ischemia Brain Induce Neuroprotection and Behavioral Improvement

(2010) Dashdemberel Narantuya et al.   PLoS One

Immunotoxic depletion of microglia in mouse hippocampal slice cultures enhances ischemia-like neurodegeneration

(2009) Maria Montero et al.   BRAIN RESEARCH

Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia

(2009) Chenhui Yang et al.   BRAIN RESEARCH

Immunoregulatory effects of HO-1: how does it work?

(2009) Miguel P Soares et al.   CURRENT OPINION IN PHARMACOLOGY

In vivoover-expression of interleukin-10 increases resistance to focal brain ischemia in mice

(2009) Fabienne de Bilbao et al.   JOURNAL OF NEUROCHEMISTRY

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

(2009) Shaheen E Lakhan et al.   Journal of Translational Medicine

Divergent Cardiopulmonary Actions of Heme Oxygenase Enzymatic Products in Chronic Hypoxia

(2009) Sally H. Vitali et al.   PLoS One

Heme oxygenase-1: from biology to therapeutic potential

(2009) Miguel P. Soares et al.   TRENDS IN MOLECULAR MEDICINE

Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia

(2008) M. Rosas-Ballina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatocyte-Specific Deletion of Heme Oxygenase-1 Disrupts Redox Homeostasis in Basal and Oxidative Environments

(2008) Takashi Mamiya et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE