The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes
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Title
The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes
Authors
Keywords
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Journal
JOURNAL OF LEUKOCYTE BIOLOGY
Volume 92, Issue 5, Pages 959-975
Publisher
Wiley
Online
2012-08-09
DOI
10.1189/jlb.0212100
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- (2017) Fernanda Matos Coelho et al. NEUROIMMUNOMODULATION
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- (2011) Roger F. Butterworth HEPATOLOGY
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- (2011) Roosmarijn C. Drexhage et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
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- (2011) David R Owen et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
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- (2011) Krister Kristensson NATURE REVIEWS NEUROSCIENCE
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- (2011) Laura Maggi Frontiers in Cellular Neuroscience
- Prenatal Infection and Schizophrenia: A Review of Epidemiologic and Translational Studies
- (2010) Alan S. Brown et al. AMERICAN JOURNAL OF PSYCHIATRY
- Autoimmune diseases, bipolar disorder, and non-affective psychosis
- (2010) William W Eaton et al. BIPOLAR DISORDERS
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- (2010) Ross J. Tynan et al. BRAIN BEHAVIOR AND IMMUNITY
- Effects of prenatal infection on brain development and behavior: A review of findings from animal models
- (2010) Patricia Boksa BRAIN BEHAVIOR AND IMMUNITY
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- (2010) Amanda Sierra et al. Cell Stem Cell
- Microglia in the developing brain: from immunity to behaviour
- (2010) Timm Schlegelmilch et al. CURRENT OPINION IN NEUROBIOLOGY
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- (2010) Roosmarijn C. Drexhage et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
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- (2009) C Rummel et al. MOLECULAR PSYCHIATRY
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- A Discriminating Messenger RNA Signature for Bipolar Disorder Formed by an Aberrant Expression of Inflammatory Genes in Monocytes
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- (2008) Maïté Moreau et al. BRAIN BEHAVIOR AND IMMUNITY
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- (2008) Marcia Kauer-Sant'Anna et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Selective contribution of interleukin-6 and leptin to brain inflammatory signals induced by systemic LPS injection in mice
- (2008) Christoph Rummel et al. JOURNAL OF COMPARATIVE NEUROLOGY
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- (2008) S. Wakselman et al. JOURNAL OF NEUROSCIENCE
- Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: an open randomised clinical trial
- (2008) René S Kahn et al. LANCET
- Ontogeny of sensorimotor gating and immune impairment induced by prenatal immune challenge in rats: implications for the etiopathology of schizophrenia
- (2008) E Romero et al. MOLECULAR PSYCHIATRY
- Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice
- (2008) J C O'Connor et al. MOLECULAR PSYCHIATRY
- Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain
- (2008) M. Cosenza-Nashat et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Brain inflammation and adult neurogenesis: The dual role of microglia
- (2008) C.T. Ekdahl et al. NEUROSCIENCE
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- (2008) S. Girard et al. NEUROSCIENCE
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- IL-1 is an essential mediator of the antineurogenic and anhedonic effects of stress
- (2008) J. W. Koo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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