Neurogenetics and Pharmacology of Learning, Motivation and Cognition

The role of the dopamine transporter DAT1 genotype on the neural correlates of cognitive flexibility

(2010) M. Garcia-Garcia et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Environmental Neurotoxic Pesticide Increases Histone Acetylation to Promote Apoptosis in Dopaminergic Neuronal Cells: Relevance to Epigenetic Mechanisms of Neurodegeneration

(2010) C. Song et al.   MOLECULAR PHARMACOLOGY

Mechanisms Underlying Dopamine-Mediated Reward Bias in Compulsive Behaviors

(2010) Valerie Voon et al.   NEURON

Distinct Roles of Synaptic Transmission in Direct and Indirect Striatal Pathways to Reward and Aversive Behavior

(2010) Takatoshi Hikida et al.   NEURON

Nucleus accumbens and effort-related functions: behavioral and neural markers of the interactions between adenosine A2A and dopamine D2 receptors

(2010) A.M. Farrar et al.   NEUROSCIENCE

Overcoming status quo bias in the human brain

(2010) S. M. Fleming et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rare Variants Create Synthetic Genome-Wide Associations

(2010) Samuel P. Dickson et al.   PLOS BIOLOGY

Reward-learning and the novelty-seeking personality: a between- and within-subjects study of the effects of dopamine agonists on young Parkinson's patients

(2009) N. Bodi et al.   BRAIN

Instructional control of reinforcement learning: A behavioral and neurocomputational investigation

(2009) Bradley B. Doll et al.   BRAIN RESEARCH

Candidate gene studies of ADHD: a meta-analytic review

(2009) Ian R. Gizer et al.   HUMAN GENETICS

Immediate and enduring effects of neonatal isolation on maternal behavior in rats

(2009) Therese A. Kosten et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Adenylyl Cyclase Type 5 Contributes to Corticostriatal Plasticity and Striatum-Dependent Learning

(2009) M. A. Kheirbek et al.   JOURNAL OF NEUROSCIENCE

Dopamine Release in Dissociable Striatal Subregions Predicts the Different Effects of Oral Methylphenidate on Reversal Learning and Spatial Working Memory

(2009) P. L. Clatworthy et al.   JOURNAL OF NEUROSCIENCE

Dopamine DRD2 Polymorphism Alters Reversal Learning and Associated Neural Activity

(2009) G. Jocham et al.   JOURNAL OF NEUROSCIENCE

Striatal Dopamine Predicts Outcome-Specific Reversal Learning and Its Sensitivity to Dopaminergic Drug Administration

(2009) R. Cools et al.   JOURNAL OF NEUROSCIENCE

Genetic Deletion of A2A Adenosine Receptors in the Striatum Selectively Impairs Habit Formation

(2009) C. Yu et al.   JOURNAL OF NEUROSCIENCE

Dopamine Transporter Genotype Conveys Familial Risk of Attention-Deficit/Hyperactivity Disorder Through Striatal Activation

(2009) SARAH DURSTON et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Prefrontal and striatal dopaminergic genes predict individual differences in exploration and exploitation

(2009) Michael J Frank et al.   NATURE NEUROSCIENCE

Motivational orientation modulates the neural response to reward

(2009) Julia Linke et al.   NEUROIMAGE

Frontal theta links prediction errors to behavioral adaptation in reinforcement learning

(2009) James F. Cavanagh et al.   NEUROIMAGE

How Green Is the Grass on the Other Side? Frontopolar Cortex and the Evidence in Favor of Alternative Courses of Action

(2009) Erie D. Boorman et al.   NEURON

Genetic contributions to avoidance-based decisions: striatal D2 receptor polymorphisms

(2009) M.J. Frank et al.   NEUROSCIENCE

Genetic association studies of performance monitoring and learning from feedback: The role of dopamine and serotonin

(2009) Markus Ullsperger   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Neural mechanisms of acquired phasic dopamine responses in learning

(2009) Thomas E. Hazy et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Genetic variation in dopaminergic neuromodulation influences the ability to rapidly and flexibly adapt decisions

(2009) L. K. Krugel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacological modulation of subliminal learning in Parkinson's and Tourette's syndromes

(2009) Stefano Palminteri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of NMDAR-dependent burst firing by dopamine neurons provides selective assessment of phasic dopamine-dependent behavior

(2009) L. S. Zweifel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caffeine and a selective adenosine A2A receptor antagonist induce reward and sensitization behavior associated with increased phospho-Thr75-DARPP-32 in mice

(2009) Chih W. Hsu et al.   PSYCHOPHARMACOLOGY

A neurocomputational account of catalepsy sensitization induced by D2 receptor blockade in rats: context dependency, extinction, and renewal

(2009) Thomas V. Wiecki et al.   PSYCHOPHARMACOLOGY

Human Substantia Nigra Neurons Encode Unexpected Financial Rewards

(2009) K. A. Zaghloul et al.   SCIENCE

Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning

(2009) H.-C. Tsai et al.   SCIENCE

Dopamine, Behavioral Economics, and Effort

(2009) John D. Salamone   Frontiers in Behavioral Neuroscience

Sapap3and pathological grooming in humans: Results from the OCD collaborative genetics study

(2008) O.J. Bienvenu et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Neurocomputational models of basal ganglia function in learning, memory and choice

(2008) Michael X. Cohen et al.   BEHAVIOURAL BRAIN RESEARCH

Epistasis between Dopamine Regulating Genes Identifies a Nonlinear Response of the Human Hippocampus During Memory Tasks

(2008) Alessandro Bertolino et al.   BIOLOGICAL PSYCHIATRY

The Dual-State Theory of Prefrontal Cortex Dopamine Function with Relevance to Catechol-O-Methyltransferase Genotypes and Schizophrenia

(2008) Daniel Durstewitz et al.   BIOLOGICAL PSYCHIATRY

Meta-Analysis of the Cognitive Effects of the Catechol-O-Methyltransferase Gene Val158/108Met Polymorphism

(2008) Jennifer H. Barnett et al.   BIOLOGICAL PSYCHIATRY

The Role of COMT Val158Met in Cognition

(2008) David Goldman et al.   BIOLOGICAL PSYCHIATRY

A Translational Profiling Approach for the Molecular Characterization of CNS Cell Types

(2008) Myriam Heiman et al.   CELL

Motivational influences on cognitive control: Behavior, brain activation, and individual differences

(2008) H. S. LOCKE et al.   COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE

Differential Excitability and Modulation of Striatal Medium Spiny Neuron Dendrites

(2008) M. Day et al.   JOURNAL OF NEUROSCIENCE

Nucleus Accumbens Adenosine A2A Receptors Regulate Exertion of Effort by Acting on the Ventral Striatopallidal Pathway

(2008) S. Mingote et al.   JOURNAL OF NEUROSCIENCE

Midbrain Dopaminergic Neurons and Striatal Cholinergic Interneurons Encode the Difference between Reward and Aversive Events at Different Epochs of Probabilistic Classical Conditioning Trials

(2008) M. Joshua et al.   JOURNAL OF NEUROSCIENCE

Working Memory Capacity Predicts Dopamine Synthesis Capacity in the Human Striatum

(2008) R. Cools et al.   JOURNAL OF NEUROSCIENCE

 FosB Mediates Epigenetic Desensitization of the c-fos Gene After Chronic Amphetamine Exposure

(2008) W. Renthal et al.   JOURNAL OF NEUROSCIENCE

Tripartite Mechanism of Extinction Suggested by Dopamine Neuron Activity and Temporal Difference Model

(2008) W.-X. Pan et al.   JOURNAL OF NEUROSCIENCE

A Role for Dopamine in Temporal Decision Making and Reward Maximization in Parkinsonism

(2008) A. A. Moustafa et al.   JOURNAL OF NEUROSCIENCE

Opposing Patterns of Signaling Activation in Dopamine D1 and D2 Receptor-Expressing Striatal Neurons in Response to Cocaine and Haloperidol

(2008) J. Bertran-Gonzalez et al.   JOURNAL OF NEUROSCIENCE

COMT genotype predicts cortical-limbic D1 receptor availability measured with [11C]NNC112 and PET

(2008) M Slifstein et al.   MOLECULAR PSYCHIATRY

A phosphatase cascade by which rewarding stimuli control nucleosomal response

(2008) Alexandre Stipanovich et al.   NATURE

Computational models of schizophrenia and dopamine modulation in the prefrontal cortex

(2008) Edmund T. Rolls et al.   NATURE REVIEWS NEUROSCIENCE

Using genetic data in cognitive neuroscience: from growing pains to genuine insights

(2008) Adam E. Green et al.   NATURE REVIEWS NEUROSCIENCE

Modulation of gamma oscillations by endogenous adenosine through A1 and A2A receptors in the mouse hippocampus

(2008) A.N. Pietersen et al.   NEUROPHARMACOLOGY

A dopaminergic basis for working memory, learning and attentional shifting in Parkinsonism

(2008) Ahmed A. Moustafa et al.   NEUROPSYCHOLOGIA

Patients with Schizophrenia have a Reduced Neural Response to Both Unpredictable and Predictable Primary Reinforcers

(2008) James A Waltz et al.   NEUROPSYCHOPHARMACOLOGY

Role of Dopamine in the Motivational and Cognitive Control of Behavior

(2008) Roshan Cools   NEUROSCIENTIST

Transient and selective overexpression of D2 receptors in the striatum causes persistent deficits in conditional associative learning

(2008) M.-E. Bach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Variation in dopamine genes influences responsivity of the human reward system

(2008) J.-C. Dreher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transfer of Learning After Updating Training Mediated by the Striatum

(2008) E. Dahlin et al.   SCIENCE

Dichotomous Dopaminergic Control of Striatal Synaptic Plasticity

(2008) W. Shen et al.   SCIENCE

High Impulsivity Predicts the Switch to Compulsive Cocaine-Taking

(2008) D. Belin et al.   SCIENCE

Genetic Variation in Catechol-O-Methyltransferase: Effects on Working Memory in Schizophrenic Patients, Their Siblings, and Healthy Controls

(2007) Catherine M. Diaz-Asper et al.   BIOLOGICAL PSYCHIATRY

Differences in genetic and environmental influences on the human cerebral cortex associated with development during childhood and adolescence

(2007) Rhoshel K. Lenroot et al.   HUMAN BRAIN MAPPING

The role of the orbitofrontal cortex in human discrimination learning

(2007) Henry W. Chase et al.   NEUROPSYCHOLOGIA