AQW051, a novel, potent and selective α7 nicotinic ACh receptor partial agonist: pharmacological characterization and phase I evaluation

Normalizing Effects of EVP-6124, an Alpha-7 Nicotinic Partial Agonist, on Event-Related Potentials and Cognition

(2014) SHELDON H. PRESKORN et al.   Journal of Psychiatric Practice

Preclinical characterization of a selective alpha-7 neuronal nicotinic acetylcholine receptor agonist ABT-126: A novel therapeutic agent for the treatment of cognitive impairment in Alzheimer's disease and schizophrenia

(2013) Robert Bitner et al.   Alzheimers & Dementia

Evaluating the role of the alpha-7 nicotinic acetylcholine receptor in the pathophysiology and treatment of schizophrenia

(2013) Jared W. Young et al.   BIOCHEMICAL PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: Ligand-Gated Ion Channels

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Randomized Exploratory Trial of an Alpha-7 Nicotinic Receptor Agonist (TC-5619) for Cognitive Enhancement in Schizophrenia

(2013) Jeffrey A Lieberman et al.   NEUROPSYCHOPHARMACOLOGY

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

(2013) Adam J. Pawson et al.   NUCLEIC ACIDS RESEARCH

Discovery of (2S,3R)-N-[2-(Pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]oct-3-yl]benzo[b]furan-2-carboxamide (TC-5619), a Selective α7 Nicotinic Acetylcholine Receptor Agonist, for the Treatment of Cognitive Disorders

(2012) Anatoly A. Mazurov et al.   JOURNAL OF MEDICINAL CHEMISTRY

Allosteric alpha-7 nicotinic receptor modulation and P50 sensory gating in schizophrenia: A proof-of-mechanism study

(2012) Georg Winterer et al.   NEUROPHARMACOLOGY

EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors

(2011) Jos Prickaerts et al.   NEUROPHARMACOLOGY

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

In Vivo Pharmacological Characterization of a Novel Selective  7 Neuronal Nicotinic Acetylcholine Receptor Agonist ABT-107: Preclinical Considerations in Alzheimer's Disease

(2010) R. S. Bitner et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

TC-5619: An alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia

(2009) T.A. Hauser et al.   BIOCHEMICAL PHARMACOLOGY

Initial Phase 2 Trial of a Nicotinic Agonist in Schizophrenia

(2008) Robert Freedman et al.   AMERICAN JOURNAL OF PSYCHIATRY

The selective nicotinic acetylcholine receptor α7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain

(2008) Dominik Feuerbach et al.   NEUROPHARMACOLOGY