Alterations of redox and iron metabolism accompany the development of HIV latency

4q-D4Z4 chromatin architecture regulates the transcription of muscle atrophic genes in Facioscapulohumeral muscular dystrophy

(2019) Alice Cortesi et al.   GENOME RESEARCH

Arsenic Trioxide Impacts Viral Latency and Delays Viral Rebound after Termination of ART in Chronically SIV‐Infected Macaques

(2019) Qing Yang et al.   Advanced Science

Potential impact of the antirheumatic agent auranofin on proviral HIV-1 DNA in individuals under intensified antiretroviral therapy: Results from a randomised clinical trial

(2019) Ricardo Sobhie Diaz et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

AT 101 induces early mitochondrial dysfunction and HMOX1 (heme oxygenase 1) to trigger mitophagic cell death in glioma cells

(2018) Nina Meyer et al.   Autophagy

PML nuclear bodies: from architecture to function

(2018) Valérie Lallemand-Breitenbach et al.   CURRENT OPINION IN CELL BIOLOGY

A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment

(2018) Marc L Hyer et al.   NATURE MEDICINE

Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress

(2018) Jiska van der Reest et al.   Nature Communications

Cellular Metabolism Is a Major Determinant of HIV-1 Reservoir Seeding in CD4+ T Cells and Offers an Opportunity to Tackle Infection

(2018) José Carlos Valle-Casuso et al.   Cell Metabolism

Single-pot, solid-phase-enhanced sample preparation for proteomics experiments

(2018) Christopher S. Hughes et al.   Nature Protocols

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

PML is a ROS sensor activating p53 upon oxidative stress

(2017) Michiko Niwa-Kawakita et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of Genetically Intact HIV-1 Proviruses in Specific CD4 + T Cells from Effectively Treated Participants

(2017) Bonnie Hiener et al.   Cell Reports

Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells

(2017) Miriam Cnop et al.   Molecular Metabolism

The Roles of NRF2 in Modulating Cellular Iron Homeostasis

(2017) Michael John Kerins et al.   ANTIOXIDANTS & REDOX SIGNALING

Modeling HIV-1 Latency in Primary T Cells Using a Replication-Competent Virus

(2016) Laura J. Martins et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Dual targeting of the thioredoxin and glutathione systems in cancer and HIV

(2016) Moran Benhar et al.   JOURNAL OF CLINICAL INVESTIGATION

Sulforaphane Inhibits HIV Infection of Macrophages through Nrf2

(2016) Andrea Kinga Marias Furuya et al.   PLoS Pathogens

Short Communication: High Cellular Iron Levels Are Associated with Increased HIV Infection and Replication

(2015) Hsiang-Chun Chang et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Bystander effects as manifestation of intercellular communication of DNA damage and of the cellular oxidative status

(2015) Holger Klammer et al.   CANCER LETTERS

Selective Sensitization of Zinc Finger Protein Oxidation by Reactive Oxygen Species through Arsenic Binding

(2015) Xixi Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques

(2015) Luca Micci et al.   JOURNAL OF CLINICAL INVESTIGATION

Two-Year Follow-Up of Macaques Developing Intermittent Control of the Human Immunodeficiency Virus Homolog Simian Immunodeficiency Virus SIVmac251 in the Chronic Phase of Infection

(2015) Iart Luca Shytaj et al.   JOURNAL OF VIROLOGY

Apoptosis-induced activation of HIV-1 in latently infected cell lines

(2015) Sohrab Z. Khan et al.   Retrovirology

TRIM19/PML Restricts HIV Infection in a Cell Type-Dependent Manner

(2015) Tanja Kahle et al.   Viruses-Basel

HIV Latency Is Established Directly and Early in Both Resting and Activated Primary CD4 T Cells

(2015) Leonard Chavez et al.   PLoS Pathogens

PML/TRIM19-Dependent Inhibition of Retroviral Reverse-Transcription by Daxx

(2015) Jacques Dutrieux et al.   PLoS Pathogens

Partial inhibition of Cdk1 in G2phase overrides the SAC and decouples mitotic events

(2014) Rachael A McCloy et al.   CELL CYCLE

The Mismetallation of Enzymes during Oxidative Stress

(2014) James A. Imlay   JOURNAL OF BIOLOGICAL CHEMISTRY

Measuring Glutathione Redox Potential of HIV-1-infected Macrophages

(2014) Ashima Bhaskar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative stress–induced assembly of PML nuclear bodies controls sumoylation of partner proteins

(2014) Umut Sahin et al.   JOURNAL OF CELL BIOLOGY

Heme oxygenase-1 deficiency accompanies neuropathogenesis of HIV-associated neurocognitive disorders

(2014) Alexander J. Gill et al.   JOURNAL OF CLINICAL INVESTIGATION

Control of antioxidative response by the tumor suppressor protein PML through regulating Nrf2 activity

(2014) Shuang Guo et al.   MOLECULAR BIOLOGY OF THE CELL

PML nuclear bodies: Assembly and oxidative stress-sensitive sumoylation

(2014) Umut Sahin et al.   Nucleus

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Proximity to PML Nuclear Bodies Regulates HIV-1 Latency in CD4+ T Cells

(2013) Marina Lusic et al.   Cell Host & Microbe

Analysis of GSH and GSSG after derivatization with N-ethylmaleimide

(2013) Daniela Giustarini et al.   Nature Protocols

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Detecting endogenous SUMO targets in mammalian cells and tissues

(2013) Janina Becker et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Investigational treatment suspension and enhanced cell-mediated immunity at rebound followed by drug-free remission of simian AIDS

(2013) Iart Shytaj et al.   Retrovirology

A candidate anti-HIV reservoir compound, auranofin, exerts a selective ‘anti-memory’ effect by exploiting the baseline oxidative status of lymphocytes

(2013) B Chirullo et al.   Cell Death & Disease

HIV Latency

(2013) R. F. Siliciano et al.   Cold Spring Harbor Perspectives in Medicine

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Development of proteasome inhibitors as research tools and cancer drugs

(2012) Alfred L. Goldberg   JOURNAL OF CELL BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Antisense 2′-Deoxy, 2′-Fluoroarabino Nucleic Acid (2′F-ANA) Oligonucleotides: In Vitro Gymnotic Silencers of Gene Expression Whose Potency Is Enhanced by Fatty Acids

(2012) Naira Souleimanian et al.   Molecular Therapy-Nucleic Acids

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mechanisms of Cell Protection by Heme Oxygenase-1

(2010) Raffaella Gozzelino et al.   Annual Review of Pharmacology and Toxicology

Hepcidin induces HIV-1 transcription inhibited by ferroportin

(2010) Min Xu et al.   Retrovirology

Arsenic Trioxide Controls the Fate of the PML-RAR  Oncoprotein by Directly Binding PML

(2010) X. W. Zhang et al.   SCIENCE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Nrf2 is involved in inhibiting Tat-induced HIV-1 long terminal repeat transactivation

(2009) Hong-Sheng Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

PML nuclear bodies as sites of epigenetic regulation

(2009) Dora Torok   Frontiers in Bioscience-Landmark

Geometric Applications of the Split Bregman Method: Segmentation and Surface Reconstruction

(2009) Tom Goldstein et al.   JOURNAL OF SCIENTIFIC COMPUTING

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

(2009) Nicolas Chomont et al.   NATURE MEDICINE

Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells

(2008) A. Bosque et al.   BLOOD

Viral infection and iron metabolism

(2008) Hal Drakesmith et al.   NATURE REVIEWS MICROBIOLOGY