Control of antioxidative response by the tumor suppressor protein PML through regulating Nrf2 activity

Trafficking of the Transcription Factor Nrf2 to Promyelocytic Leukemia-Nuclear Bodies

(2013) Melanie Theodore Malloy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ablation of Promyelocytic Leukemia Protein (PML) Re-patterns Energy Balance and Protects Mice from Obesity Induced by a Western Diet

(2013) Xiwen Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monoubiquitination of Filamin B Regulates Vascular Endothelial Growth Factor-Mediated Trafficking of Histone Deacetylase 7

(2013) Y.-T. Su et al.   MOLECULAR AND CELLULAR BIOLOGY

Promyelocytic Leukemia Protein (PML) Regulates Endothelial Cell Network Formation and Migration in Response to Tumor Necrosis Factor α (TNFα) and Interferon α (IFNα)

(2012) Xiwen Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acute promyelocytic leukemia, arsenic, and PML bodies

(2012) Hugues de Thé et al.   JOURNAL OF CELL BIOLOGY

A metabolic prosurvival role for PML in breast cancer

(2012) Arkaitz Carracedo et al.   JOURNAL OF CLINICAL INVESTIGATION

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

(2012) Keisuke Ito et al.   NATURE MEDICINE

Promyelocytic leukemia inhibits adipogenesis, and loss of promyelocytic leukemia results in fat accumulation in mice

(2011) Myung K. Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Curing APL through PML/RARA degradation by As2O3

(2011) Valerie Lallemand-Breitenbach et al.   TRENDS IN MOLECULAR MEDICINE

The inhibition of autophagy potentiates anti-angiogenic effects of sulforaphane by inducing apoptosis

(2010) Takeshi Nishikawa et al.   ANGIOGENESIS

PML/RARA Oxidation and Arsenic Binding Initiate the Antileukemia Response of As2O3

(2010) Marion Jeanne et al.   CANCER CELL

SENP3-mediated De-conjugation of SUMO2/3 from Promyelocytic Leukemia Is Correlated with Accelerated Cell Proliferation under Mild Oxidative Stress

(2010) Yan Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arsenic Trioxide Controls the Fate of the PML-RAR  Oncoprotein by Directly Binding PML

(2010) X. W. Zhang et al.   SCIENCE

PML Regulates Apoptosis at Endoplasmic Reticulum by Modulating Calcium Release

(2010) C. Giorgi et al.   SCIENCE

PML Nuclear Bodies

(2010) V. Lallemand-Breitenbach et al.   Cold Spring Harbor Perspectives in Biology

Puromycin-based vectors promote a ROS-dependent recruitment of PML to nuclear inclusions enriched with HSP70 and Proteasomes

(2009) Diarmuid M Moran et al.   BMC CELL BIOLOGY

Novel Aspects of Oxidative Stress in Cardiovascular Diseases

(2009) Donald D. Heistad et al.   CIRCULATION JOURNAL

G Protein Pathway Suppressor 2 (GPS2) Is a Transcriptional Corepressor Important for Estrogen Receptor α-mediated Transcriptional Regulation

(2009) Xiwen Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of SUMO in RNF4-mediated Promyelocytic Leukemia Protein (PML) Degradation

(2009) Yann Percherancier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Sulforaphane generates reactive oxygen species leading to mitochondrial perturbation for apoptosis in human leukemia U937 cells

(2008) Woo Young Choi et al.   BIOMEDICINE & PHARMACOTHERAPY

Loss of Keap1 Function Activates Nrf2 and Provides Advantages for Lung Cancer Cell Growth

(2008) T. Ohta et al.   CANCER RESEARCH

Arsenic trioxide stimulates SUMO-2/3 modification leading to RNF4-dependent proteolytic targeting of PML

(2008) Stefan R. Weisshaar et al.   FEBS LETTERS

Phosphorylation of Nrf2 in the transcription activation domain by casein kinase 2 (CK2) is critical for the nuclear translocation and transcription activation function of Nrf2 in IMR-32 neuroblastoma cells

(2008) Patrick L. Apopa et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity

(2008) T. Yamamoto et al.   MOLECULAR AND CELLULAR BIOLOGY

Signal-dependent Regulation of Transcription by Histone Deacetylase 7 Involves Recruitment to Promyelocytic Leukemia Protein Nuclear Bodies

(2008) Chengzhuo Gao et al.   MOLECULAR BIOLOGY OF THE CELL

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY

The role of Nrf2 in increased reactive oxygen species and DNA damage in prostate tumorigenesis

(2008) D A Frohlich et al.   ONCOGENE