Dehydroepiandrosterone (DHEA) and its Sulphate (DHEAS) in Alzheimer’s Disease
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Dehydroepiandrosterone (DHEA) and its Sulphate (DHEAS) in Alzheimer’s Disease
Authors
Keywords
-
Journal
Current Alzheimer Research
Volume 17, Issue 2, Pages 141-157
Publisher
Bentham Science Publishers Ltd.
Online
2020-03-17
DOI
10.2174/1567205017666200317092310
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate in Alzheimer's Disease: A Systematic Review and Meta-Analysis
- (2019) Xiongfeng Pan et al. Frontiers in Aging Neuroscience
- Gene-environment interactions in Alzheimer's disease: A potential path to precision medicine
- (2019) Aseel Eid et al. PHARMACOLOGY & THERAPEUTICS
- Evidence for brain glucose dysregulation in Alzheimer's disease
- (2018) Yang An et al. Alzheimers & Dementia
- 2018 Alzheimer's disease facts and figures
- (2018) Alzheimers & Dementia
- Tau in Alzheimer's Disease: Mechanisms and Therapeutic Strategies
- (2018) Yu Gao et al. Current Alzheimer Research
- Dehydroepiandrosterone rehabilitate BRL-3A cells oxidative stress damage induced by hydrogen peroxide
- (2018) Longlong Li et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Neurosteroids: non-genomic pathways in neuroplasticity and involvement in neurological diseases
- (2018) Marina Schverer et al. PHARMACOLOGY & THERAPEUTICS
- Amyloid toxicity in Alzheimer’s disease
- (2018) Allison B. Reiss et al. REVIEWS IN THE NEUROSCIENCES
- Oxidative stress, aging, and diseases
- (2018) Ilaria Liguori et al. Clinical Interventions in Aging
- Short overview on metabolomic approach and redox changes in psychiatric disorders
- (2018) Gordana Nedic Erjavec et al. Redox Biology
- A Lead Study on Oxidative Stress-Mediated Dehydroepiandrosterone Formation in Serum: The Biochemical Basis for a Diagnosis of Alzheimer's Disease
- (2018) Georges Rammouz et al. JOURNAL OF ALZHEIMERS DISEASE
- Central intracrine DHEA synthesis in ageing-related neuroinflammation and neurodegeneration: therapeutic potential?
- (2018) Y S L Powrie et al. Journal of Neuroinflammation
- Circulating levels of IL-1 family cytokines and receptors in Alzheimer’s disease: new markers of disease progression?
- (2018) Paola Italiani et al. Journal of Neuroinflammation
- Cortisol and DHEA in development and psychopathology
- (2017) Hayley S. Kamin et al. HORMONES AND BEHAVIOR
- Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease
- (2017) Eric Tönnies et al. JOURNAL OF ALZHEIMERS DISEASE
- Uptake and metabolism of sulphated steroids by the blood-brain barrier in the adult male rat
- (2017) M. Zeeshan Qaiser et al. JOURNAL OF NEUROCHEMISTRY
- Peripheral inflammatory markers in Alzheimer’s disease: a systematic review and meta-analysis of 175 studies
- (2017) Ka Sing P Lai et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- The role of dehydroepiandrosterone on functional innate immune responses to acute stress
- (2017) Sean P. Prall et al. STRESS AND HEALTH
- Dehydroepiandrosterone protects male and female hippocampal neurons and neuroblastoma cells from glucose deprivation
- (2016) Claudia Vieira-Marques et al. BRAIN RESEARCH
- Microtubule and microtubule associated protein anomalies in psychiatric disease
- (2016) Francesca Marchisella et al. Cytoskeleton
- Serum dehydroepiandrosterone levels are associated with lower risk of type 2 diabetes: the Rotterdam Study
- (2016) Adela Brahimaj et al. DIABETOLOGIA
- Dehydroepiandrosterone Stimulation of Osteoblastogenesis in Human MSCs Requires IGF-I Signaling
- (2016) Xiaonan Liang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Novel mechanisms for DHEA action
- (2016) Russell A Prough et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Nongenomic actions of neurosteroid pregnenolone and its metabolites
- (2016) Jui-Hsia Weng et al. STEROIDS
- Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer’s disease: metabolic basis for dementia
- (2016) Jingshu Xu et al. Scientific Reports
- Dehydroepiandrosterone administration improves memory deficits following transient brain ischemia through sigma-1 receptor stimulation
- (2015) Yasushi Yabuki et al. BRAIN RESEARCH
- Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein
- (2015) Amandine Grimm et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The Regulation of Steroid Action by Sulfation and Desulfation
- (2015) Jonathan W. Mueller et al. ENDOCRINE REVIEWS
- DHEA and cognitive function in the elderly
- (2015) Marcello Maggio et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Neuroinflammation in Alzheimer's disease
- (2015) Michael T Heneka et al. LANCET NEUROLOGY
- DHEA metabolism to the neurosteroid androsterone: a possible mechanism of DHEA’s antidepressant action
- (2015) Rivka Ben Dor et al. PSYCHOPHARMACOLOGY
- Calcium and ROS: A mutual interplay
- (2015) Agnes Görlach et al. Redox Biology
- Redox Control of Microglial Function: Molecular Mechanisms and Functional Significance
- (2014) Ana I. Rojo et al. ANTIOXIDANTS & REDOX SIGNALING
- Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes to Alzheimer Disease
- (2014) F. G. De Felice et al. DIABETES
- Type 3 diabetes is sporadic Alzheimer׳s disease: Mini-review
- (2014) Suzanne M. de la Monte EUROPEAN NEUROPSYCHOPHARMACOLOGY
- The Benefits and Harms of Systemic Dehydroepiandrosterone (DHEA) in Postmenopausal Women With Normal Adrenal Function: A Systematic Review and Meta-analysis
- (2014) Tarig Elraiyah et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Dehydroepiandrosterone-induces miR-21 transcription in HepG2 cells through estrogen receptor β and androgen receptor
- (2014) Yun Teng et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Neuroprotection by the synthetic neurosteroid enantiomers ent-PREGS and ent-DHEAS against Aβ25–35 peptide-induced toxicity in vitro and in vivo in mice
- (2014) Fadia El Bitar et al. PSYCHOPHARMACOLOGY
- Neuroprotective–neurotrophic effect of endogenous dehydroepiandrosterone sulfate during intense stress exposure
- (2014) Marcus K. Taylor et al. STEROIDS
- Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake
- (2013) Joanne C. McNelis et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Altered Expression of Diabetes-Related Genes in Alzheimer's Disease Brains: The Hisayama Study
- (2013) Masaaki Hokama et al. CEREBRAL CORTEX
- Dehydroepiandrosterone Supplementation in Elderly Men: A Meta-Analysis Study of Placebo-Controlled Trials
- (2013) Giovanni Corona et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Association of serum dehydroepiandrosterone sulfate and cognition in older adults: Sex steroid, inflammatory, and metabolic mechanisms.
- (2013) Kerry L. Hildreth et al. NEUROPSYCHOLOGY
- Blockade of Tau Hyperphosphorylation and Aβ1–42 Generation by the Aminotetrahydrofuran Derivative ANAVEX2-73, a Mixed Muscarinic and σ1 Receptor Agonist, in a Nontransgenic Mouse Model of Alzheimer’s Disease
- (2013) Valentine Lahmy et al. NEUROPSYCHOPHARMACOLOGY
- Stimulation of the Sigma-1 Receptor by DHEA Enhances Synaptic Efficacy and Neurogenesis in the Hippocampal Dentate Gyrus of Olfactory Bulbectomized Mice
- (2013) Shigeki Moriguchi et al. PLoS One
- Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: Implications for diagnostic and therapeutic strategies
- (2013) Zhichun Chen et al. PROGRESS IN NEUROBIOLOGY
- Dehydroepiandrosterone (DHEA) inhibits voltage-gated T-type calcium channels
- (2012) M. Chevalier et al. BIOCHEMICAL PHARMACOLOGY
- Neuroinflammation, Oxidative Stress and the Pathogenesis of Alzheimers Disease
- (2012) Paula Agostinho et al. CURRENT PHARMACEUTICAL DESIGN
- Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
- (2012) Konrad Talbot et al. JOURNAL OF CLINICAL INVESTIGATION
- Alzheimer's Disease, Oestrogen and Mitochondria: an Ambiguous Relationship
- (2012) Amandine Grimm et al. MOLECULAR NEUROBIOLOGY
- The neurosteroid dehydroepiandrosterone (DHEA) protects the retina from AMPA-induced excitotoxicity: NGF TrkA receptor involvement
- (2012) Despina Kokona et al. NEUROPHARMACOLOGY
- Antioxidant Therapies for Alzheimer's Disease
- (2012) Ye Feng et al. Oxidative Medicine and Cellular Longevity
- Modulation of Recombinant GABAA Receptors by Neurosteroid Dehydroepiandrosterone Sulfate
- (2012) Dubravka Švob Štrac et al. PHARMACOLOGY
- Mitochondria-Specific Accumulation of Amyloid β Induces Mitochondrial Dysfunction Leading to Apoptotic Cell Death
- (2012) Moon-Yong Cha et al. PLoS One
- Oxidative Stress and Antioxidant Defense
- (2012) Esra Birben et al. World Allergy Organization Journal
- DHEAS induces short-term potentiation via the activation of a metabotropic glutamate receptor in the rat hippocampus
- (2011) Yuxia Xu et al. HIPPOCAMPUS
- Dehydroepiandrosterone-Induced Phosphorylation and Translocation of FoxO1 Depend on the Mineralocorticoid Receptor
- (2011) Carsten Lindschau et al. HYPERTENSION
- Dehydroepiandrosterone (DHEA)—A Precursor Steroid or an Active Hormone in Human Physiology (CME)
- (2011) Abdulmaged M. Traish et al. Journal of Sexual Medicine
- Neurosteroid Dehydroepiandrosterone Interacts with Nerve Growth Factor (NGF) Receptors, Preventing Neuronal Apoptosis
- (2011) Iakovos Lazaridis et al. PLOS BIOLOGY
- Oxidative Stress-Mediated Brain Dehydroepiandrosterone (DHEA) Formation in Alzheimer?s Disease Diagnosis
- (2011) Georges Rammouz et al. Frontiers in Endocrinology
- Allosteric modulation of the NMDA receptor by neurosteroids in rat brain and the impact of long term morphine administration
- (2010) Tobias Johansson et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Dehydroepiandrosterone (DHEA): A Steroid with Multiple Effects. Is there Any Possible Option in the Treatment of Critical illness?
- (2010) R. Oberbeck et al. CURRENT MEDICINAL CHEMISTRY
- Involvement of nitric oxide in the protective effects of dehydroepiandrosterone sulphate on stress induced neurobehavioral suppression and brain oxidative injury in rats
- (2010) Ayanabha Chakraborti et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Effects of dehydroepiandrosterone supplementation on cognitive function and activities of daily living in older women with mild to moderate cognitive impairment
- (2010) Shizuru Yamada et al. Geriatrics & Gerontology International
- Alzheimer's disease: clinical trials and drug development
- (2010) Francesca Mangialasche et al. LANCET NEUROLOGY
- DHEA prevents Aβ25–35-impaired survival of newborn neurons in the dentate gyrus through a modulation of PI3K-Akt-mTOR signaling
- (2010) Liang Li et al. NEUROPHARMACOLOGY
- Dehydroepiandrosterone and age-related cognitive decline
- (2009) Krystina G. Sorwell et al. AGE
- GROWTH FACTORS DECREASE IN SUBJECTS WITH MILD TO MODERATE ALZHEIMER'S DISEASE (AD): POTENTIAL CORRECTION WITH DEHYDROEPIANDROSTERONE-SULPHATE (DHEAS)
- (2009) C. Luppi et al. ARCHIVES OF GERONTOLOGY AND GERIATRICS
- Intrathecal injection of the neurosteroid, DHEAS, produces mechanical allodynia in mice: involvement of spinal sigma-1 and GABAA receptors
- (2009) Seo-Yeon Yoon et al. BRITISH JOURNAL OF PHARMACOLOGY
- Calcium dyshomeostasis and neurotoxicity of Alzheimer’s β-amyloid protein
- (2009) Masahiro Kawahara et al. Expert Review of Neurotherapeutics
- Genome-wide analysis of DHEA- and DHT-induced gene expression in mouse hypothalamus and hippocampus
- (2009) Qianxing Mo et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Molecular inflammation: Underpinnings of aging and age-related diseases
- (2008) Hae Young Chung et al. AGEING RESEARCH REVIEWS
- Effect of dehydroepiandrosterone (DHEA) on monoamine oxidase activity, lipid peroxidation and lipofuscin accumulation in aging rat brain regions
- (2008) Pardeep Kumar et al. BIOGERONTOLOGY
- Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS)
- (2008) Nicole Maninger et al. FRONTIERS IN NEUROENDOCRINOLOGY
- Cerebrospinal Fluid Dehydroepiandrosterone Levels Are Correlated with Brain Dehydroepiandrosterone Levels, Elevated in Alzheimer’s Disease, and Related to Neuropathological Disease Stage
- (2008) Jennifer C. Naylor et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Neurosteroid dehydroepiandrosterone exerts anti-apoptotic effects by membrane-mediated, integrated genomic and non-genomic pro-survival signaling pathways
- (2008) Ioannis Charalampopoulos et al. JOURNAL OF NEUROCHEMISTRY
- Dehydroepiandrosterone modulates antioxidant enzymes and Akt signaling in healthy Wistar rat hearts
- (2008) Maria H.V.M. Jacob et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Effects of Dehydroepiandrosterone Supplementation on Cognitive Function and Quality of Life: The DHEA and Well-Ness (DAWN) Trial
- (2008) Donna Kritz-Silverstein et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Acute dehydroepiandrosterone treatment exerts different effects on dopamine and serotonin turnover ratios in the rat corpus striatum and nucleus accumbens
- (2008) Iván Pérez-Neri et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Dehydroepiandrosterone in systemic lupus erythematosus
- (2008) Amr H. Sawalha et al. Current Rheumatology Reports
- DHEAS repeated treatment improves cognitive and behavioral deficits after mild traumatic brain injury
- (2007) A. Milman et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Neurosteroid dehydroepiandrosterone sulphate inhibits persistent sodium currents in rat medial prefrontal cortex via activation of sigma-1 receptors
- (2007) Zheng-Xiang Cheng et al. EXPERIMENTAL NEUROLOGY
- Modulation of neurotransmitter systems by dehydroepiandrosterone and dehydroepiandrosterone sulfate: Mechanism of action and relevance to psychiatric disorders
- (2007) Iván Pérez-Neri et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started