The impact of probiotics, prebiotics, and synbiotics on the biochemical, clinical, and immunological markers, as well as on the gut microbiota of obese hosts

Whole Food–Based Approaches to Modulating Gut Microbiota and Associated Diseases

(2020) Yanhui Han et al.   Annual Review of Food Science and Technology

Effects of Synbiotic Supplement on Human Gut Microbiota, Body Composition and Weight Loss in Obesity

(2020) Igor N. Sergeev et al.   Nutrients

Metagenomic Analysis of Duodenal Microbiota Reveals a Potential Biomarker of Dysbiosis in the Course of Obesity and Type 2 Diabetes: A Pilot Study

(2020) Agnieszka Sroka-Oleksiak et al.   Journal of Clinical Medicine

Effcts of probiotic yogurt on glycemic indexes and endothelial dysfunction markers in subjects with metabolic syndrome

(2019) Leila Rezazadeh et al.   NUTRITION

Short‐chain fatty acids: Bacterial messengers modulating the immunometabolism of T cells

(2019) Maik Luu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Akkermansia muciniphila is a promising probiotic

(2019) Ting Zhang et al.   Microbial Biotechnology

Connection between gut microbiome and the development of obesity

(2019) Cuiting Zhi et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study

(2019) Clara Depommier et al.   NATURE MEDICINE

Lactobacillus reuteri V3401 Reduces Inflammatory Biomarkers and Modifies the Gastrointestinal Microbiome in Adults with Metabolic Syndrome: The PROSIR Study

(2019) Carmen Tenorio-Jiménez et al.   Nutrients

In vitro effects of Bifidobacterium lactis-based synbiotics on human faecal bacteria

(2019) Fernanda C. Henrique-Bana et al.   FOOD RESEARCH INTERNATIONAL

The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease

(2018) Kassem Makki et al.   Cell Host & Microbe

Probiotic Lactobacillus paracasei HII01 protects rats against obese-insulin resistance-induced kidney injury and impaired renal organic anion transporter 3 (Oat3) function

(2018) Keerati Wanchai et al.   CLINICAL SCIENCE

Specific synbiotics in early life protect against diet-induced obesity in adult mice

(2018) Mona Mischke et al.   DIABETES OBESITY & METABOLISM

Probiotics and nutraceuticals as a new frontier in obesity prevention and management

(2018) N. Kobyliak et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Gut microbiota and obesity: Concepts relevant to clinical care

(2018) Maria Carlota Dao et al.   European Journal of Internal Medicine

Histological improvement of non-alcoholic steatohepatitis with a prebiotic: a pilot clinical trial

(2018) Marc R. Bomhof et al.   EUROPEAN JOURNAL OF NUTRITION

Role of prebiotics in regulation of microbiota and prevention of obesity

(2018) Grethel Teresa Choque Delgado et al.   FOOD RESEARCH INTERNATIONAL

Influence of Probiotics Administration on Gut Microbiota Core

(2018) Silvia Falcinelli et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

The prebiotic inulin improves substrate metabolism and promotes short-chain fatty acid production in overweight to obese men

(2018) Christina M. van der Beek et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Gut Microbes and Health: A Focus on the Mechanisms Linking Microbes, Obesity, and Related Disorders

(2018) Marialetizia Rastelli et al.   Obesity

Microbiota in obesity: interactions with enteroendocrine, immune and central nervous systems

(2018) R. J. Mulders et al.   Obesity Reviews

Dietary nutrition and gut microflora: A promising target for treating diseases

(2018) Ying Nie et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Dose-Dependent Effects of Multispecies Probiotic Supplementation on the Lipopolysaccharide (LPS) Level and Cardiometabolic Profile in Obese Postmenopausal Women: A 12-Week Randomized Clinical Trial

(2018) Monika Szulińska et al.   Nutrients

Microbiome-Mediated Effects of the Mediterranean Diet on Inflammation

(2018) Melisa A Bailey et al.   Advances in Nutrition

The role of the gut microbiome in systemic inflammatory disease

(2018) Jose C Clemente et al.   BMJ-British Medical Journal

The role of the gut microbiome in systemic inflammatory disease

(2018) Jose C Clemente et al.   BMJ-British Medical Journal

The Gut-Brain Axis, the Human Gut Microbiota and Their Integration in the Development of Obesity

(2018) Edward S. Bliss et al.   Frontiers in Physiology

Dietary Alteration of the Gut Microbiome and Its Impact on Weight and Fat Mass: A Systematic Review and Meta-Analysis

(2018) George John et al.   Genes

Effect of Bifidobacterium lactis HN019 on inflammatory markers and oxidative stress in subjects with and without the metabolic syndrome

(2018) Luciana J. Bernini et al.   BRITISH JOURNAL OF NUTRITION

Adipose tissue inflammation and metabolic syndrome. The proactive role of probiotics

(2018) Sebastian Torres et al.   EUROPEAN JOURNAL OF NUTRITION

Efficacy of synbiotic supplementation in obesity treatment: A systematic review and meta-analysis of clinical trials

(2018) Amir Hadi et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Alterations in gut microbiota composition and metabolic parameters after dietary intervention with barley beta glucans in patients with high risk for metabolic syndrome development

(2018) Ana Velikonja et al.   ANAEROBE

Supplementation of Diet With Galacto-oligosaccharides Increases Bifidobacteria, but Not Insulin Sensitivity, in Obese Prediabetic Individuals

(2017) Emanuel E. Canfora et al.   GASTROENTEROLOGY

Prebiotics Reduce Body Fat and Alter Intestinal Microbiota in Children Who Are Overweight or With Obesity

(2017) Alissa C. Nicolucci et al.   GASTROENTEROLOGY

Effect of Lactobacillus on body weight and body fat in overweight subjects: a systematic review of randomized controlled clinical trials

(2017) L Crovesy et al.   INTERNATIONAL JOURNAL OF OBESITY

Probiotics modulate gut microbiota and improve insulin sensitivity in DIO mice

(2017) Renata A. Bagarolli et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Repertoire of human gut microbes

(2017) Perrine Hugon et al.   MICROBIAL PATHOGENESIS

Microbiota manipulation for weight change

(2017) Tal Dror et al.   MICROBIAL PATHOGENESIS

Inulin-type fructans and whey protein both modulate appetite but only fructans alter gut microbiota in adults with overweight/obesity: A randomized controlled trial

(2017) Raylene A. Reimer et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

(2017) Glenn R. Gibson et al.   Nature Reviews Gastroenterology & Hepatology

Weight-loss interventions and gut microbiota changes in overweight and obese patients: a systematic review

(2017) F. B. Seganfredo et al.   Obesity Reviews

Effects of probiotics on body weight, body mass index, fat mass and fat percentage in subjects with overweight or obesity: a systematic review and meta-analysis of randomized controlled trials

(2017) H. Borgeraas et al.   Obesity Reviews

Are the Gut Bacteria Telling Us to Eat or Not to Eat? Reviewing the Role of Gut Microbiota in the Etiology, Disease Progression and Treatment of Eating Disorders

(2017) Yan Lam et al.   Nutrients

Beneficial metabolic effects of selected probiotics on diet-induced obesity and insulin resistance in mice are associated with improvement of dysbiotic gut microbiota

(2016) Jeanne Alard et al.   ENVIRONMENTAL MICROBIOLOGY

Antiobesity effect of Pediococcus pentosaceus LP28 on overweight subjects: a randomized, double-blind, placebo-controlled clinical trial

(2016) F Higashikawa et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Effect of probiotics and synbiotics on blood glucose: a systematic review and meta-analysis of controlled trials

(2016) Elham Nikbakht et al.   EUROPEAN JOURNAL OF NUTRITION

Beneficial effects of Bifidobacterium lactis on lipid profile and cytokines in patients with metabolic syndrome: A randomized trial. Effects of probiotics on metabolic syndrome

(2016) Luciana Jesus Bernini et al.   NUTRITION

Probiotics in prevention and treatment of obesity: a critical view

(2016) Nazarii Kobyliak et al.   Nutrition & Metabolism

The additional effects of a probiotic mix on abdominal adiposity and antioxidant Status: A double-blind, randomized trial

(2016) Aline Corado Gomes et al.   Obesity

Gut microbiota, obesity and diabetes

(2016) Elaine Patterson et al.   POSTGRADUATE MEDICAL JOURNAL

Microbiome and metabolic disorders related to obesity: Which lessons to learn from experimental models?

(2016) Audrey M. Neyrinck et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Arabinogalactan and fructooligosaccharides improve the gut barrier function in distinct areas of the colon in the Simulator of the Human Intestinal Microbial Ecosystem

(2016) David Daguet et al.   Journal of Functional Foods

Probiotic With or Without Fiber Controls Body Fat Mass, Associated With Serum Zonulin, in Overweight and Obese Adults—Randomized Controlled Trial

(2016) Lotta K. Stenman et al.   EBioMedicine

Diet-induced changes in maternal gut microbiota and metabolomic profiles influence programming of offspring obesity risk in rats

(2016) Heather A. Paul et al.   Scientific Reports

Comparison of the effect of daily consumption of probiotic compared with low-fat conventional yogurt on weight loss in healthy obese women following an energy-restricted diet: a randomized controlled trial1

(2015) Ameneh Madjd et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Regulation of energy balance by a gut–brain axis and involvement of the gut microbiota

(2015) Paige V. Bauer et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A systematic review and meta-analysis of the prebiotics and synbiotics effects on glycaemia, insulin concentrations and lipid parameters in adult patients with overweight or obesity

(2015) Bruna T.S. Beserra et al.   CLINICAL NUTRITION

Inulin-type fructans modulate intestinal Bifidobacterium species populations and decrease fecal short-chain fatty acids in obese women

(2015) Nuria Salazar et al.   CLINICAL NUTRITION

The role of short chain fatty acids in appetite regulation and energy homeostasis

(2015) C S Byrne et al.   INTERNATIONAL JOURNAL OF OBESITY

Gastrointestinal microbiome modulator improves glucose tolerance in overweight and obese subjects: A randomized controlled pilot trial

(2015) Candida J. Rebello et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Supplementation with two probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032, reduced body adiposity and Lp-PLA2 activity in overweight subjects

(2015) Saem Jung et al.   Journal of Functional Foods

The effects of co-administration of probiotics with herbal medicine on obesity, metabolic endotoxemia and dysbiosis: A randomized double-blind controlled clinical trial

(2014) Sin Ji Lee et al.   CLINICAL NUTRITION

The probioticLactobacillus coryniformisCECT5711 reduces the vascular pro-oxidant and pro-inflammatory status in obese mice

(2014) Marta Toral et al.   CLINICAL SCIENCE

Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity

(2014) Amandine Everard et al.   ISME Journal

Effects of Probiotic Yogurt on Fat Distribution and Gene Expression of Proinflammatory Factors in Peripheral Blood Mononuclear Cells in Overweight and Obese People with or without Weight-Loss Diet

(2014) Mitra Zarrati et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic

(2014) Colin Hill et al.   Nature Reviews Gastroenterology & Hepatology

A natural solution for obesity: Bioactives for the prevention and treatment of weight gain. A review

(2014) Cristina Torres-Fuentes et al.   NUTRITIONAL NEUROSCIENCE

Changes in satiety hormone concentrations and feed intake in rats in response to lactic acid bacteria

(2013) Sofia D. Forssten et al.   APPETITE

Metabolic benefits of dietary prebiotics in human subjects: a systematic review of randomised controlled trials

(2013) Nicole J. Kellow et al.   BRITISH JOURNAL OF NUTRITION

Effect of Lactobacillus rhamnosus CGMCC1.3724 supplementation on weight loss and maintenance in obese men and women

(2013) Marina Sanchez et al.   BRITISH JOURNAL OF NUTRITION

Effect of Lactobacillus gasseri SBT2055 in fermented milk on abdominal adiposity in adults in a randomised controlled trial

(2013) Yukio Kadooka et al.   BRITISH JOURNAL OF NUTRITION

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

Anti-obesity effect of Lactobacillus gasseri SBT2055 accompanied by inhibition of pro-inflammatory gene expression in the visceral adipose tissue in diet-induced obese mice

(2013) Masaya Miyoshi et al.   EUROPEAN JOURNAL OF NUTRITION

Beneficial Metabolic Effects of a Probiotic via Butyrate-induced GLP-1 Hormone Secretion

(2013) Hariom Yadav et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Hypocaloric diet supplemented with probiotic cheese improves body mass index and blood pressure indices of obese hypertensive patients - a randomized double-blind placebo-controlled pilot study

(2013) Khaider K Sharafedtinov et al.   Nutrition Journal

BifidobacteriumCECT 7765 improves metabolic and immunological alterations associated with obesity in high-fat diet-fed mice

(2013) Paola Gauffin Cano et al.   Obesity

Combined effects of oligofructose andBifidobacterium animalison gut microbiota and glycemia in obese rats

(2013) Marc R. Bomhof et al.   Obesity

Supplementation of Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 in Diet-Induced Obese Mice Is Associated with Gut Microbial Changes and Reduction in Obesity

(2013) Do-Young Park et al.   PLoS One

Microbial Reprogramming Inhibits Western Diet-Associated Obesity

(2013) Theofilos Poutahidis et al.   PLoS One

The influence of probiotic supplementation on gut permeability in patients with metabolic syndrome: an open label, randomized pilot study

(2012) B Leber et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women

(2012) Evelyne M Dewulf et al.   GUT

Bile Acid Binding Resin Improves Metabolic Control through the Induction of Energy Expenditure

(2012) Mitsuhiro Watanabe et al.   PLoS One

Bacteroides uniformis CECT 7771 Ameliorates Metabolic and Immunological Dysfunction in Mice with High-Fat-Diet Induced Obesity

(2012) Paola Gauffin Cano et al.   PLoS One

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

(2011) G. Tolhurst et al.   DIABETES

The relationship between gut microbiota and weight gain in humans

(2011) Emmanouil Angelakis et al.   Future Microbiology

Regulation of Inflammation by Short Chain Fatty Acids

(2011) Marco A.R. Vinolo et al.   Nutrients

Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial

(2010) Y Kadooka et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal

(2009) Patrice D Cani et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Safety of supplementing infant formula with long-chain polyunsaturated fatty acids and Bifidobacterium lactis in term infants: a randomised controlled trial

(2009) Robert A. Gibson et al.   BRITISH JOURNAL OF NUTRITION

The Role of the Gut Microbiota in Energy Metabolism and Metabolic Disease

(2009) Patrice Cani et al.   CURRENT PHARMACEUTICAL DESIGN

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

Specific metabolite production by gut microbiota as a basis for probiotic function

(2009) R.P. Ross et al.   INTERNATIONAL DAIRY JOURNAL