Adipocyte lipolysis: from molecular mechanisms of regulation to disease and therapeutics
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Adipocyte lipolysis: from molecular mechanisms of regulation to disease and therapeutics
Authors
Keywords
-
Journal
BIOCHEMICAL JOURNAL
Volume 477, Issue 5, Pages 985-1008
Publisher
Portland Press Ltd.
Online
2020-03-13
DOI
10.1042/bcj20190468
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Adipocyte extracellular vesicles carry enzymes and fatty acids that stimulate mitochondrial metabolism and remodeling in tumor cells
- (2020) Emily Clement et al. EMBO JOURNAL
- Adipokine FABP4 integrates energy stores and counter regulatory metabolic responses
- (2019) Kacey J. Prentice et al. JOURNAL OF LIPID RESEARCH
- The AAA+ ATPase/ubiquitin ligase mysterin stabilizes cytoplasmic lipid droplets
- (2019) Munechika Sugihara et al. JOURNAL OF CELL BIOLOGY
- PNPLA3, CGI-58, and Inhibition of Hepatic Triglyceride Hydrolysis in Mice
- (2019) Yang Wang et al. HEPATOLOGY
- Identification of an intrinsic lysophosphatidic acid acyltransferase activity in the lipolytic inhibitor G0/G1 switch gene 2 (G0S2)
- (2019) Xiaodong Zhang et al. FASEB JOURNAL
- A Unique Role of Carboxylesterase 3 (Ces3) in β-Adrenergic Signaling Stimulated Thermogenesis
- (2019) Li Yang et al. DIABETES
- Discovery of FAHFA-Containing Triacylglycerols and Their Metabolic Regulation
- (2019) Dan Tan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis
- (2019) Soumik BasuRay et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation
- (2019) Jacqueline Stöckli et al. Molecular Metabolism
- An Epistatic Interaction between Pnpla2 and Lipe Reveals New Pathways of Adipose Tissue Lipolysis
- (2019) Xiao Zhang et al. Cells
- Unconventional Secretion Of Adipocyte Fatty Acid Binding Protein 4 Is Mediated By Autophagic Proteins In a Sirtuin-1 Dependent Manner
- (2019) Ajeetha Josephrajan et al. DIABETES
- Atrial Natriuretic Peptide: A Molecular Target of Novel Therapeutic Approaches to Cardio-Metabolic Disease
- (2019) Valentina Cannone et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Targeting a ceramide double bond improves insulin resistance and hepatic steatosis
- (2019) Bhagirath Chaurasia et al. SCIENCE
- Insulin and β-adrenergic receptors mediate lipolytic and anti-lipolytic signalling that is not altered by type 2 diabetes in human adipocytes
- (2019) Cecilia Jönsson et al. BIOCHEMICAL JOURNAL
- Lung cancer-derived extracellular vesicles induced myotube atrophy and adipocyte lipolysis via the extracellular IL-6-mediated STAT3 pathway
- (2019) Wenjun Hu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms
- (2019) Peng Zhou et al. JOURNAL OF CLINICAL INVESTIGATION
- Prostate tumor cell-derived IL-1β induces an inflammatory phenotype in bone marrow adipocytes and reduces sensitivity to docetaxel via lipolysis-dependent mechanisms
- (2019) Mackenzie K Herroon et al. MOLECULAR CANCER RESEARCH
- Adipose lipid turnover and long-term changes in body weight
- (2019) P. Arner et al. NATURE MEDICINE
- Targeted protein degradation: expanding the toolbox
- (2019) Matthieu Schapira et al. NATURE REVIEWS DRUG DISCOVERY
- Cellular quality control by the ubiquitin-proteasome system and autophagy
- (2019) Christian Pohl et al. SCIENCE
- Genetically-encoded sensors to detect fatty acid production and trafficking
- (2019) Emilio P. Mottillo et al. Molecular Metabolism
- Lipokine 5-PAHSA Is Regulated by Adipose Triglyceride Lipase and Primes Adipocytes for De Novo Lipogenesis in Mice
- (2019) Veronika Paluchova et al. DIABETES
- Utilization of adipocyte-derived lipids and enhanced intracellular trafficking of fatty acids contribute to breast cancer progression
- (2018) Dejuan Yang et al. Cell Communication and Signaling
- Lipolysis Triggers a Systemic Insulin Response Essential for Efficient Energy Replenishment of Activated Brown Adipose Tissue in Mice
- (2018) Markus Heine et al. Cell Metabolism
- Patatin-like phospholipase domain–containing protein 3 promotes transfers of essential fatty acids from triglycerides to phospholipids in hepatic lipid droplets
- (2018) Matthew A. Mitsche et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hypoxia-inducible lipid droplet-associated protein inhibits adipose triglyceride lipase
- (2018) Krishna M. Padmanabha Das et al. JOURNAL OF LIPID RESEARCH
- Loss of ABHD15 Impairs the Anti-lipolytic Action of Insulin by Altering PDE3B Stability and Contributes to Insulin Resistance
- (2018) Wenmin Xia et al. Cell Reports
- Fatty acid oxidation is required for active and quiescent brown adipose tissue maintenance and thermogenic programing
- (2018) Elsie Gonzalez-Hurtado et al. Molecular Metabolism
- Regulation of human brown adipose tissue by adenosine and A2A receptors – studies with [15O]H2O and [11C]TMSX PET/CT
- (2018) Minna Lahesmaa et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Adipose tissue browning in cancer-associated cachexia can be attenuated by inhibition of exosome generation
- (2018) Wenjun Hu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State
- (2018) Clair Crewe et al. CELL
- Molecular mechanism of the ichthyosis pathology of Chanarin–Dorfman syndrome: Stimulation of PNPLA1-catalyzed ω-O-acylceramide production by ABHD5
- (2018) Yusuke Ohno et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- ABHD5 stimulates PNPLA1-mediated ω-O-acylceramide biosynthesis essential for a functional skin permeability barrier
- (2018) Benedikt Kien et al. JOURNAL OF LIPID RESEARCH
- Tumour-originated exosomal miR-155 triggers cancer-associated cachexia to promote tumour progression
- (2018) Qi Wu et al. Molecular Cancer
- High doses of ANP and BNP exacerbate lipolysis in humans and the lipolytic effect of BNP is associated with cardiac triglyceride content in pigs
- (2018) Emil D. Bartels et al. PEPTIDES
- Hypoxia-Inducible Lipid Droplet–Associated Is Not a Direct Physiological Regulator of Lipolysis in Adipose Tissue
- (2017) Wieneke Dijk et al. ENDOCRINOLOGY
- The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation
- (2017) Soumik BasuRay et al. HEPATOLOGY
- Unconventional secretion of FABP4 by endosomes and secretory lysosomes
- (2017) Julien Villeneuve et al. JOURNAL OF CELL BIOLOGY
- Novel Pharmacological Probes Reveal ABHD5 as a Locus of Lipolysis Control in White and Brown Adipocytes
- (2017) Elizabeth A. Rondini et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing
- (2017) Christina D. Camell et al. NATURE
- Adipose-derived circulating miRNAs regulate gene expression in other tissues
- (2017) Thomas Thomou et al. NATURE
- The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue
- (2017) Matthew D Lynes et al. NATURE MEDICINE
- Enhancing natriuretic peptide signaling in adipose tissue, but not in muscle, protects against diet-induced obesity and insulin resistance
- (2017) Wei Wu et al. Science Signaling
- Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice
- (2017) Martina Schweiger et al. Nature Communications
- Adipose tissue deficiency of hormone-sensitive lipase causes fatty liver in mice
- (2017) Bo Xia et al. PLoS Genetics
- Inhibition of intracellular lipolysis promotes human cancer cell adaptation to hypoxia
- (2017) Xiaodong Zhang et al. eLife
- Enhancing natriuretic peptide signaling in adipose tissue, but not in muscle, protects against diet-induced obesity and insulin resistance
- (2017) Wei Wu et al. Science Signaling
- Molecular Basis of ABHD5 Lipolysis Activation
- (2017) Matthew A. Sanders et al. Scientific Reports
- Visualization of lipid directed dynamics of perilipin 1 in human primary adipocytes
- (2017) Jesper S. Hansen et al. Scientific Reports
- HomozygousLIPEmutation in siblings with multiple symmetric lipomatosis, partial lipodystrophy, and myopathy
- (2016) Sagit Zolotov et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Adipocyte Exosomes Promote Melanoma Aggressiveness through Fatty Acid Oxidation: A Novel Mechanism Linking Obesity and Cancer
- (2016) Ikrame Lazar et al. CANCER RESEARCH
- Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production
- (2016) Paul M. Titchenell et al. Cell Metabolism
- Ubiquitin Ligase COP1 Controls Hepatic Fat Metabolism by Targeting ATGL for Degradation
- (2016) Mainak Ghosh et al. DIABETES
- The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux
- (2016) Varman T. Samuel et al. JOURNAL OF CLINICAL INVESTIGATION
- Impaired adipose tissue lipid storage, but not altered lipolysis, contributes to elevated levels of NEFA in type 2 diabetes. Degree of hyperglycemia and adiposity are important factors
- (2016) Maria J Pereira et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Targeting adipose tissue in the treatment of obesity-associated diabetes
- (2016) Christine M. Kusminski et al. NATURE REVIEWS DRUG DISCOVERY
- Regulation of G0/G1 Switch Gene 2 (G0S2) Protein Ubiquitination and Stability by Triglyceride Accumulation and ATGL Interaction
- (2016) Bradlee L. Heckmann et al. PLoS One
- Lipolysis sensation by white fat afferent nerves triggers brown fat thermogenesis
- (2016) John T. Garretson et al. Molecular Metabolism
- Adipocyte-specific Hypoxia-inducible gene 2 promotes fat deposition and diet-induced insulin resistance
- (2016) Marina T. DiStefano et al. Molecular Metabolism
- Adipose triglyceride lipase deletion from adipocytes, but not skeletal myocytes, impairs acute exercise performance in mice
- (2015) John J. Dubé et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells
- (2015) Ulrike Taschler et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes
- (2015) Rachel J. Perry et al. CELL
- Endogenous and Synthetic ABHD5 Ligands Regulate ABHD5-Perilipin Interactions and Lipolysis in Fat and Muscle
- (2015) Matthew A. Sanders et al. Cell Metabolism
- Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist
- (2015) Aaron M. Cypess et al. Cell Metabolism
- The role of mouse Akt2 in insulin-dependent suppression of adipocyte lipolysis in vivo
- (2015) Shlomit Koren et al. DIABETOLOGIA
- Impact of Reduced ATGL-Mediated Adipocyte Lipolysis on Obesity-Associated Insulin Resistance and Inflammation in Male Mice
- (2015) Gabriele Schoiswohl et al. ENDOCRINOLOGY
- Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue
- (2015) Gunisha Sagar et al. GUT
- Impaired atrial natriuretic peptide-mediated lipolysis in obesity
- (2015) M Rydén et al. INTERNATIONAL JOURNAL OF OBESITY
- Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling
- (2015) Peter Hofer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Lipid Droplet Protein Hypoxia-inducible Gene 2 Promotes Hepatic Triglyceride Deposition by Inhibiting Lipolysis
- (2015) Marina T. DiStefano et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Selective Insulin Resistance in Adipocytes
- (2015) Shi-Xiong Tan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids
- (2015) Doris Jaeger et al. JOURNAL OF HEPATOLOGY
- The Role of PDE3B Phosphorylation in the Inhibition of Lipolysis by Insulin
- (2015) Lisa M. DiPilato et al. MOLECULAR AND CELLULAR BIOLOGY
- Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity
- (2015) Renate Schreiber et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The genetics of lipid storage and human lipodystrophies
- (2015) Ann L. Robbins et al. TRENDS IN MOLECULAR MEDICINE
- Adipose Fatty Acid Oxidation Is Required for Thermogenesis and Potentiates Oxidative Stress-Induced Inflammation
- (2015) Jieun Lee et al. Cell Reports
- Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A
- (2014) Harald M. Nagy et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- A Novel LIPE Nonsense Mutation Found Using Exome Sequencing in Siblings With Late-Onset Familial Partial Lipodystrophy
- (2014) Sali M.K. Farhan et al. CANADIAN JOURNAL OF CARDIOLOGY
- The Interplay of Protein Kinase A and Perilipin 5 Regulates Cardiac Lipolysis
- (2014) Nina M. Pollak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Peptide Derived from G0/G1Switch Gene 2 Acts as Noncompetitive Inhibitor of Adipose Triglyceride Lipase
- (2014) Ines K. Cerk et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PNPLA3 mediates hepatocyte triacylglycerol remodeling
- (2014) Hanna Ruhanen et al. JOURNAL OF LIPID RESEARCH
- Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation
- (2014) Emilio P. Mottillo et al. JOURNAL OF LIPID RESEARCH
- Comparative gene identification 58/α/β hydrolase domain 5 lacks lysophosphatidic acid acyltransferase activity
- (2014) Derek McMahon et al. JOURNAL OF LIPID RESEARCH
- Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity
- (2014) Meric Erikci Ertunc et al. JOURNAL OF LIPID RESEARCH
- Contributions of white and brown adipose tissues and skeletal muscles to acute cold-induced metabolic responses in healthy men
- (2014) Denis P. Blondin et al. JOURNAL OF PHYSIOLOGY-LONDON
- Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia
- (2014) Serkan Kir et al. NATURE
- Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors
- (2014) Thorsten Gnad et al. NATURE
- Null Mutation in Hormone-Sensitive Lipase Gene and Risk of Type 2 Diabetes
- (2014) Jessica S. Albert et al. NEW ENGLAND JOURNAL OF MEDICINE
- Regulation of adipocyte lipolysis
- (2014) Gema Frühbeck et al. NUTRITION RESEARCH REVIEWS
- FABP4 is secreted from adipocytes by adenyl cyclase-PKA- and guanylyl cyclase-PKG-dependent lipolytic mechanisms
- (2014) Tomohiro Mita et al. Obesity
- Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans
- (2014) Julia Szendroedi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Perilipins 2 and 3 lack a carboxy-terminal domain present in perilipin 1 involved in sequestering ABHD5 and suppressing basal lipolysis
- (2014) S. Patel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease
- (2013) Yuki Kawano et al. JOURNAL OF GASTROENTEROLOGY
- 15O PET Measurement of Blood Flow and Oxygen Consumption in Cold-Activated Human Brown Fat
- (2013) O. Muzik et al. JOURNAL OF NUCLEAR MEDICINE
- Selective β3-Adrenoceptor Agonists for the Treatment of Overactive Bladder
- (2013) Karl-Erik Andersson et al. JOURNAL OF UROLOGY
- Development of small-molecule inhibitors targeting adipose triglyceride lipase
- (2013) Nicole Mayer et al. Nature Chemical Biology
- CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance
- (2013) J. L. Cantley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover
- (2013) James A. Olzmann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PNPLA3 I148M polymorphism and progressive liver disease
- (2013) Paola Dongiovanni WORLD JOURNAL OF GASTROENTEROLOGY
- Mechanism of Fatty-Acid-Dependent UCP1 Uncoupling in Brown Fat Mitochondria
- (2012) Andriy Fedorenko et al. CELL
- FAT SIGNALS - Lipases and Lipolysis in Lipid Metabolism and Signaling
- (2012) Rudolf Zechner et al. Cell Metabolism
- Adiponutrin Functions as a Nutritionally Regulated Lysophosphatidic Acid Acyltransferase
- (2012) Manju Kumari et al. Cell Metabolism
- Lipolytic Products Activate Peroxisome Proliferator-activated Receptor (PPAR) α and δ in Brown Adipocytes to Match Fatty Acid Oxidation with Supply
- (2012) Emilio P. Mottillo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Studies on the Substrate and Stereo/Regioselectivity of Adipose Triglyceride Lipase, Hormone-sensitive Lipase, and Diacylglycerol-O-acyltransferases
- (2012) Thomas O. Eichmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes
- (2012) Marica Bordicchia et al. JOURNAL OF CLINICAL INVESTIGATION
- JNK Expression by Macrophages Promotes Obesity-Induced Insulin Resistance and Inflammation
- (2012) M. S. Han et al. SCIENCE
- Desnutrin/ATGL Is Regulated by AMPK and Is Required for a Brown Adipose Phenotype
- (2011) Maryam Ahmadian et al. Cell Metabolism
- Mouse patatin-like phospholipase domain-containing 3 influences systemic lipid and glucose homeostasis
- (2011) Aijun Qiao et al. HEPATOLOGY
- Deficiency of liver adipose triglyceride lipase in mice causes progressive hepatic steatosis
- (2011) Jiang Wei Wu et al. HEPATOLOGY
- Relative Contribution of Adipose Triglyceride Lipase and Hormone-sensitive Lipase to Tumor Necrosis Factor-α (TNF-α)-induced Lipolysis in Adipocytes
- (2011) Xingyuan Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Monoglyceride Lipase Deficiency in Mice Impairs Lipolysis and Attenuates Diet-induced Insulin Resistance
- (2011) Ulrike Taschler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human Frame Shift Mutations Affecting the Carboxyl Terminus of Perilipin Increase Lipolysis by Failing to Sequester the Adipose Triglyceride Lipase (ATGL) Coactivator AB-hydrolase-containing 5 (ABHD5)
- (2011) Sheetal Gandotra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Expression and Characterization of a PNPLA3 Protein Isoform (I148M) Associated with Nonalcoholic Fatty Liver Disease
- (2011) Yongcheng Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ceramides as modulators of cellular and whole-body metabolism
- (2011) Benjamin T. Bikman et al. JOURNAL OF CLINICAL INVESTIGATION
- Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
- (2011) Kristin M Nieman et al. NATURE MEDICINE
- The Minimal Domain of Adipose Triglyceride Lipase (ATGL) Ranges until Leucine 254 and Can Be Activated and Inhibited by CGI-58 and G0S2, Respectively
- (2011) Irina Cornaciu et al. PLoS One
- Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia
- (2011) S. K. Das et al. SCIENCE
- Challenges in β3-adrenoceptor agonist drug development
- (2011) Jonathan R. S. Arch Therapeutic Advances in Endocrinology and Metabolism
- β3-adrenergic receptor induction of adipocyte inflammation requires lipolytic activation of stress kinases p38 and JNK
- (2010) Emilio P. Mottillo et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Hormone-sensitive lipase modulates adipose metabolism through PPARγ
- (2010) Wen-Jun Shen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation
- (2010) E. Rysman et al. CANCER RESEARCH
- The G0/G1 Switch Gene 2 Regulates Adipose Lipolysis through Association with Adipose Triglyceride Lipase
- (2010) Xingyuan Yang et al. Cell Metabolism
- Hypoxia-inducible protein 2 is a novel lipid droplet protein and a specific target gene of hypoxia-inducible factor-1
- (2010) Tina Gimm et al. FASEB JOURNAL
- Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning
- (2010) Kuok Teong Ong et al. HEPATOLOGY
- Patatin-Like phospholipase domain-containing 3 I148M polymorphism, steatosis, and liver damage in chronic hepatitis C
- (2010) Luca Valenti et al. HEPATOLOGY
- The 148M allele of the PNPLA3 gene is associated with indices of liver damage early in life
- (2010) Stefano Romeo et al. JOURNAL OF HEPATOLOGY
- GPR40 is partially required for insulin secretion following activation of β3-adrenergic receptors
- (2010) Zhen Pang et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- A feed-forward loop amplifies nutritional regulation of PNPLA3
- (2010) Yongcheng Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity
- (2010) Roger H. Unger et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5
- (2009) Martina Schweiger et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Adipose Overexpression of Desnutrin Promotes Fatty Acid Use and Attenuates Diet-Induced Obesity
- (2009) M. Ahmadian et al. DIABETES
- Hormone-sensitive lipase (HSL) is also a retinyl ester hydrolase: evidence from mice lacking HSL
- (2009) Kristoffer Ström et al. FASEB JOURNAL
- Perilipin Controls Lipolysis by Regulating the Interactions of AB-hydrolase Containing 5 (Abhd5) and Adipose Triglyceride Lipase (Atgl)
- (2009) James G. Granneman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functional interaction of hormone-sensitive lipase and perilipin in lipolysis
- (2009) Wen-Jun Shen et al. JOURNAL OF LIPID RESEARCH
- CGI-58/ABHD5 is a coenzyme A-dependent lysophosphatidic acid acyltransferase
- (2009) Gabriela Montero-Moran et al. JOURNAL OF LIPID RESEARCH
- Fat and Beyond: The Diverse Biology of PPARγ
- (2008) Peter Tontonoz et al. Annual Review of Biochemistry
- Selective versus Total Insulin Resistance: A Pathogenic Paradox
- (2008) Michael S. Brown et al. Cell Metabolism
- Induced release of membrane vesicles from rat adipocytes containing glycosylphosphatidylinositol-anchored microdomain and lipid droplet signalling proteins
- (2008) Günter Müller et al. CELLULAR SIGNALLING
- Atrial Natriuretic Peptide Induces Postprandial Lipid Oxidation in Humans
- (2008) A. L. Birkenfeld et al. DIABETES
- Plasma Ceramides Are Elevated in Obese Subjects With Type 2 Diabetes and Correlate With the Severity of Insulin Resistance
- (2008) J. M. Haus et al. DIABETES
- Adipose tissue fatty acid metabolism in insulin-resistant men
- (2008) A. S. T. Bickerton et al. DIABETOLOGIA
- CGI-58, the Causative Gene for Chanarin-Dorfman Syndrome, Mediates Acylation of Lysophosphatidic Acid
- (2008) Ananda K. Ghosh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- AMP-activated Protein Kinase Is Activated as a Consequence of Lipolysis in the Adipocyte
- (2008) Marie-Soleil Gauthier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
- (2008) Stefano Romeo et al. NATURE GENETICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started