Challenges in β3-adrenoceptor agonist drug development

Nutrient Modification of the Innate Immune Response

(2010) Eric A. Schwartz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Heterocyclic acetamide and benzamide derivatives as potent and selective β3-adrenergic receptor agonists with improved rodent pharmacokinetic profiles

(2010) Stephen D. Goble et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Ligand-directed signalling at β-adrenoceptors

(2010) Bronwyn A. Evans et al.   BRITISH JOURNAL OF PHARMACOLOGY

UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

(2009) Helena M. Feldmann et al.   Cell Metabolism

Antidiabetic Properties of Zinc-α2-Glycoprotein inob/obMice

(2009) Steven T. Russell et al.   ENDOCRINOLOGY

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

The β3-adrenoceptor as a therapeutic target: Current perspectives

(2009) Maria Grazia Ursino et al.   PHARMACOLOGICAL RESEARCH

Insulin sensitivity: modulation by nutrients and inflammation

(2008) Simon Schenk et al.   JOURNAL OF CLINICAL INVESTIGATION

Saturated Fatty Acid-Mediated Inflammation and Insulin Resistance in Adipose Tissue: Mechanisms of Action and Implications

(2008) Arion Kennedy et al.   JOURNAL OF NUTRITION

The discovery of drugs for obesity, the metabolic effects of leptin and variable receptor pharmacology: perspectives from β3-adrenoceptor agonists

(2008) Jonathan R. S. Arch   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY