The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation
Authors
Keywords
-
Journal
HEPATOLOGY
Volume 66, Issue 4, Pages 1111-1124
Publisher
Wiley
Online
2017-05-18
DOI
10.1002/hep.29273
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Inactivation ofTm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins
- (2016) Eriks Smagris et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Perilipin2 plays a positive role in adipocytes during lipolysis by escaping proteasomal degradation
- (2016) Yu Takahashi et al. Scientific Reports
- Fasting upregulates adipose triglyceride lipase and hormone-sensitive lipase levels and phosphorylation in mouse kidney
- (2015) Phillip M. Marvyn et al. Biochemistry and Cell Biology
- Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis
- (2015) Susmita Kaushik et al. NATURE CELL BIOLOGY
- Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
- (2014) Daniel J. Klionsky et al. Autophagy
- Pnpla3I148Mknockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis
- (2014) Eriks Smagris et al. HEPATOLOGY
- PNPLA3 mediates hepatocyte triacylglycerol remodeling
- (2014) Hanna Ruhanen et al. JOURNAL OF LIPID RESEARCH
- Substrate recognition in selective autophagy and the ubiquitin–proteasome system
- (2013) Anne Schreiber et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- PNPLA3/adiponutrin functions in lipid droplet formation
- (2013) Zeina Chamoun et al. BIOLOGY OF THE CELL
- PNPLA3 I148M variant and hepatocellular carcinoma: A common genetic variant for a rare disease
- (2013) Luca Valenti et al. DIGESTIVE AND LIVER DISEASE
- Adiponutrin Functions as a Nutritionally Regulated Lysophosphatidic Acid Acyltransferase
- (2012) Manju Kumari et al. Cell Metabolism
- Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis
- (2012) John Zhong Li et al. JOURNAL OF CLINICAL INVESTIGATION
- Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro
- (2012) Carlo Pirazzi et al. JOURNAL OF HEPATOLOGY
- Autophagy as a new therapeutic target in Duchenne muscular dystrophy
- (2012) C De Palma et al. Cell Death & Disease
- Autophagy is increased in laminin α2 chain-deficient muscle and its inhibition improves muscle morphology in a mouse model of MDC1A
- (2011) Virginie Carmignac et al. HUMAN MOLECULAR GENETICS
- Expression and Characterization of a PNPLA3 Protein Isoform (I148M) Associated with Nonalcoholic Fatty Liver Disease
- (2011) Yongcheng Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human Fatty Liver Disease: Old Questions and New Insights
- (2011) J. C. Cohen et al. SCIENCE
- Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease
- (2010) Weiqin Chen et al. HEPATOLOGY
- Fat-specific Protein 27 Undergoes Ubiquitin-dependent Degradation Regulated by Triacylglycerol Synthesis and Lipid Droplet Formation
- (2010) Zongqian Nian et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SIRT4 Regulates Fatty Acid Oxidation and Mitochondrial Gene Expression in Liver and Muscle Cells
- (2010) Nargis Nasrin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome
- (2010) Mahesh K. Basantani et al. JOURNAL OF LIPID RESEARCH
- A feed-forward loop amplifies nutritional regulation of PNPLA3
- (2010) Yongcheng Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis
- (2009) Shaoqing He et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Accelerated Fatty Acid Oxidation in Muscle Averts Fasting-induced Hepatic Steatosis in SJL/J Mice
- (2009) Hong-Ping Guan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity
- (2009) Silvia Sookoian et al. JOURNAL OF LIPID RESEARCH
- Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice
- (2008) Young-Ah Moon et al. JOURNAL OF LIPID RESEARCH
- Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
- (2008) Stefano Romeo et al. NATURE GENETICS
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started