Recent advances in Cu-catalyzed C(sp3)–Si and C(sp3)–B bond formation

Reductive Coupling between Aromatic Aldehydes and Ketones or Imines by Copper Catalysis

(2019) Mitsutaka Takeda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NHC-Copper-Catalyzed Asymmetric Conjugate Silylation of Access Chiral α-Aminosilanes

(2019) Yajuan Zhang et al.   TETRAHEDRON LETTERS

Copper-Catalyzed Asymmetric Conjugate Additions of Bis(pinacolato)diboron and Dimethylzinc to Acyl-N-methylimidazole Michael Acceptors: A Highly Stereoselective Unified Strategy for 1,3,5,...n (OH, Me) Motif Synthesis

(2019) Jimmy Lauberteaux et al.   ORGANIC LETTERS

Tertiary α-Silyl Alcohols by Diastereoselective Coupling of 1,3-Dienes and Acylsilanes Initiated by Enantioselective Copper-Catalyzed Borylation

(2019) Jian-Jun Feng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Regio- and Enantioselective Addition of Silicon Grignard Reagents to Alkenes Activated by Azaaryl Groups

(2019) Wenbin Mao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Mechanism of Copper‐Catalyzed Trifunctionalization of Terminal Allenes

(2019) Hong Ki Kim et al.   CHEMISTRY-A EUROPEAN JOURNAL

Regiodivergent and Stereospecific Aziridine Opening by Copper‐Catalyzed Addition of Silicon Grignard Reagents

(2019) Hong Yi et al.   CHEMISTRY-A EUROPEAN JOURNAL

meta-Selective C–H Borylation of Benzamides and Pyridines by an Iridium–Lewis Acid Bifunctional Catalyst

(2019) Lichen Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Regioselective Borylfluoromethylation of Alkenes

(2019) Nuo-Yi Wu et al.   ACS Catalysis

Copper(I)-Catalyzed Enantioconvergent Borylation of Racemic Benzyl Chlorides Enabled by Quadrant-by-Quadrant Structure Modification of Chiral Bisphosphine Ligands

(2019) Hiroaki Iwamoto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper‐Catalyzed Enantio‐ and Diastereoselective Addition of Silicon Nucleophiles to 3,3‐Disubstituted Cyclopropenes

(2019) Liangliang Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Copper-Catalyzed Carbon–Silicon Bond Formation

(2019) Jake R. Wilkinson et al.   ACS Catalysis

Frontispiece: Catalytic Enantioselective Synthesis of Allylic Boronates Bearing a Trisubstituted Alkenyl Fluoride and Related Derivatives

(2019) Sota Akiyama et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cu‐NHC‐Catalyzed Enantioselective Conjugate Silyl addition to Indol‐1‐ylacrylate Derivatives

(2019) Jun‐Jian Shen et al.   ChemistrySelect

Copper-Catalyzed Heteroarylboration of 1,3-Dienes with 3-Bromopyridines: A cine Substitution

(2018) Kevin B. Smith et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper(I)-Catalyzed Enantio- and Diastereodivergent Borylative Coupling of Styrenes and Imines

(2018) Taisuke Itoh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Copper(I)-Catalyzed Enantioselective γ-Boryl Substitution of Trifluoromethyl-Substituted Alkenes: Synthesis of Enantioenriched γ,γ-gem -Difluoroallylboronates

(2018) Ryoto Kojima et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regiodivergent copper catalyzed borocyanation of 1,3-dienes

(2018) Tao Jia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic palladium/copper-catalyzed Csp3–Csp2 cross-couplings using aldehydes as latent α-alkoxyalkyl anion equivalents

(2018) Mitsutaka Takeda et al.   CHEMICAL COMMUNICATIONS

Asymmetric Construction of Fluoroalkyl Tertiary Alcohols through a Three-Component Reaction of (Bpin)2, 1,3-Enynes, and Fluoroalkyl Ketones Catalyzed by a Copper(I) Complex

(2018) Xu-Cheng Gan et al.   ORGANIC LETTERS

Enantioselective Copper-Catalyzed Methylboration of Alkenes

(2018) Bin Chen et al.   ORGANIC LETTERS

Copper-Catalyzed Silylation of C(sp3)–H Bonds Adjacent to Amide Nitrogen Atoms

(2018) Jian-Jun Feng et al.   ORGANIC LETTERS

Catalytically Asymmetric Synthesis of 1,3-Bis(silyl)propenes via Copper-Catalyzed Double Proto-Silylations of Polar Enynes

(2018) Fei-Fan Meng et al.   ACS Catalysis

Copper-Catalyzed Stereo- and Enantioselective 1,4-Protosilylation of α,β-Unsaturated Ketimines To Synthesize Functionalized Allylsilanes

(2018) Bing-Chao Da et al.   ACS Catalysis

Copper-boryl mediated organic synthesis

(2018) David Hemming et al.   CHEMICAL SOCIETY REVIEWS

Copper-Catalyzed Double C(sp3)–Si Coupling of Geminal Dibromides: Ionic-to-Radical Switch in the Reaction Mechanism

(2018) Hamideh Hazrati et al.   ORGANIC LETTERS

Cu-Catalyzed Decarboxylative Borylation

(2018) Jie Wang et al.   ACS Catalysis

Catalyst-Controlled 1,2- and 1,1-Arylboration of α-Alkyl Alkenyl Arenes

(2018) Allison M. Bergmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NHC-Copper-Catalyzed Asymmetric Dearomative Silylation of Indoles

(2018) Yongjia Shi et al.   JOURNAL OF ORGANIC CHEMISTRY

Fluoroalkylation–Borylation of Alkynes: An Efficient Method To Obtain (Z)-Tri- and Tetrasubstituted Fluoroalkylated Alkenylboronates

(2018) Wen-Hao Guo et al.   ACS Catalysis

C(sp3)–Si Cross-Coupling

(2018) Susanne Bähr et al.   ACS Catalysis

Progress in the medicinal chemistry of silicon: C/Si exchange and beyond

(2017) Shinya Fujii et al.   Future Medicinal Chemistry

Copper-Catalyzed Carbenoid Insertion Reactions of α-Diazoesters and α-Diazoketones into Si–H and S–H Bonds

(2017) Hoda Keipour et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanistic Studies of Copper-Catalyzed Asymmetric Hydroboration of Alkenes

(2017) Yumeng Xi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Copper Hydride-Catalyzed Markovnikov Hydrosilylation of Vinylarenes and Vinyl Heterocycles

(2017) Michael W. Gribble et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The versatility of boron in biological target engagement

(2017) Diego B. Diaz et al.   Nature Chemistry

Recent progress in the catalytic carbene insertion reactions into the silicon–hydrogen bond

(2017) Hoda Keipour et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Copper-Catalyzed Substitution of α-Triflyloxy Nitriles and Esters with Silicon Nucleophiles under Inversion of the Configuration

(2017) Jonas Scharfbier et al.   ORGANIC LETTERS

Synthesis of Benzyl-, Allyl-, and Allenyl-boronates via Copper-Catalyzed Borylation of Alcohols

(2017) Lujia Mao et al.   ORGANIC LETTERS

Copper-Catalyzed Silylperoxidation Reaction of α,β-Unsaturated Ketones, Esters, Amides, and Conjugated Enynes

(2017) Yun Lan et al.   ACS Catalysis

Enantioselective Synthesis of Cyclobutylboronates via a Copper-Catalyzed Desymmetrization Approach

(2016) Manuel Guisán-Ceinos et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Arylboration of Alkenylarenes

(2016) Kaitlyn M. Logan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Diastereo- and Enantioselective Cu-Catalyzed Borylative Coupling of 1,3-Dienes and Aldimines

(2016) Liyin Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Conjugate Additions of (pin)B-Substituted Allylcopper Compounds Generated in situ from Butadiene or Isoprene

(2016) Xiben Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines

(2016) Joshua J. Smith et al.   CHEMICAL COMMUNICATIONS

Diboron(4) Compounds: From Structural Curiosity to Synthetic Workhorse

(2016) Emily C. Neeve et al.   CHEMICAL REVIEWS

Copper-Catalyzed Enantioselective Addition of Styrene-Derived Nucleophiles to Imines Enabled by Ligand-Controlled Chemoselective Hydrocupration

(2016) Yang Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diverse Asymmetric Hydrofunctionalization of Aliphatic Internal Alkenes through Catalytic Regioselective Hydroboration

(2016) Yumeng Xi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Cross-Coupling of Silicon Pronucleophiles with Unactivated Alkyl Electrophiles Coupled with Radical Cyclization

(2016) Weichao Xue et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cascade Copper-Catalyzed 1,2,3-Trifunctionalization of Terminal Allenes

(2016) Wanxiang Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Arylboration of 1-Arylalkenes by Cooperative Nickel/Copper Catalysis

(2016) Kazuhiko Semba et al.   ORGANIC LETTERS

Regioselective Copper-Catalyzed Boracarboxylation of Vinyl Arenes

(2016) Trevor W. Butcher et al.   ORGANIC LETTERS

Copper-Catalyzed Si–B Bond Activation in the Nucleophilic Substitution of Primary Aliphatic Triflates

(2016) Martin Oestreich et al.   SYNLETT

Highly Efficient Synthesis of Alkylboronate Esters via Cu(II)-Catalyzed Borylation of Unactivated Alkyl Bromides and Chlorides in Air

(2016) Shubhankar Kumar Bose et al.   ACS Catalysis

Evolution of Solvents in Organic Chemistry

(2016) Bruce H. Lipshutz et al.   ACS Sustainable Chemistry & Engineering

Chemoselective catalytic reduction of conjugated α,β-unsaturated ketones to saturated ketones via a hydroboration/protodeboronation strategy

(2016) Wen Ding et al.   Organic Chemistry Frontiers

[2.2]Paracyclophane-based N-heterocyclic carbene as efficient catalyst or as ligand for copper catalyst for asymmetric α-silylation of N-tosylaldimines

(2016) Zhen Chen et al.   Organic Chemistry Frontiers

Ligand-Controlled Regiodivergent Copper-Catalyzed Alkylboration of Alkenes

(2015) Wei Su et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regio- and Stereospecific 1,3-Allyl Group Transfer Triggered by a Copper-Catalyzed Borylation/ortho -Cyanation Cascade

(2015) Yang Yang   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Functionalization of Styrenes by Copper-Catalyzed Borylation/ortho-Cyanation and Silver-Catalyzed Annulation Processes

(2015) Wanxiang Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper/Palladium Synergistic Catalysis for thesyn- andanti-Selective Carboboration of Alkenes

(2015) Kaitlyn M. Logan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-catalyzed silylation of p-quinone methides: new entry to dibenzylic silanes

(2015) Aurora López et al.   CHEMICAL COMMUNICATIONS

Catalytic Silylation of Unactivated C–H Bonds

(2015) Chen Cheng et al.   CHEMICAL REVIEWS

Can Silicon Make an Excellent Drug Even Better? An in vitro and in vivo Head-to-Head Comparison between Loperamide and Its Silicon Analogue Sila-Loperamide

(2015) Marcel Geyer et al.   ChemMedChem

A Cu/Pd Cooperative Catalysis for Enantioselective Allylboration of Alkenes

(2015) Tao Jia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Insoluble Copper(II) Acetylacetonate–Chiral Bipyridine Complex that Catalyzes Asymmetric Silyl Conjugate Addition in Water

(2015) Taku Kitanosono et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-Controlled Regiodivergent Cu-Catalyzed Aminoboration of Unactivated Terminal Alkenes

(2015) Ryosuke Sakae et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Free Radical Cascade Silylarylation of Activated Alkenes: Highly Selective Activation of the Si–H/C–H Bonds

(2015) Lizhi Zhang et al.   ORGANIC LETTERS

Copper-Catalyzed Borylative Aromatization of p-Quinone Methides: Enantioselective Synthesis of Dibenzylic Boronates

(2015) Carlos Jarava-Barrera et al.   ACS Catalysis

Enantioselective Addition of Silicon Nucleophiles to Aldimines Using a Preformed NHC-Copper(I) Complex as the Catalyst

(2014) Alexander Hensel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transitioning organic synthesis from organic solvents to water. What's your E Factor?

(2014) Bruce H. Lipshutz et al.   GREEN CHEMISTRY

Homologation of Boronic Esters with Organolithium Compounds: A Computational Assessment of Mechanism

(2014) Stéphanie Essafi et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper(I)-Catalyzed Enantioselective Nucleophilic Borylation of Aldehydes: An Efficient Route to Enantiomerically Enriched α-Alkoxyorganoboronate Esters

(2014) Koji Kubota et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Regiodivergent Silacarboxylation of Allenes with Carbon Dioxide and a Silylborane

(2014) Yosuke Tani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper(I)-Catalyzed Enantioselective Synthesis of α-Chiral Linear or Carbocyclic (E)-(γ-Alkoxyallyl)boronates

(2014) Eiji Yamamoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective Silylation of N-Sulfonylimines: Asymmetric Synthesis of α-Amino Acids from CO2 via Stereospecific Carboxylation of α-Amino Silanes

(2014) Tsuyoshi Mita et al.   ORGANIC LETTERS

CuI-Catalyzed Conjugate Addition of Silyl Boronic Esters: Retracing Catalytic Cycles Using Isolated Copper and Boron Enolate Intermediates

(2014) Jacqueline Plotzitzka et al.   ORGANOMETALLICS

McQuade’s Six-Membered NHC–Copper(I) Complexes for Catalytic Asymmetric­ Silyl Transfer

(2014) Martin Oestreich et al.   SYNTHESIS-STUTTGART

Enantioselective Syntheses of α-Silyl Amines via a Copper-N-Heterocyclic Carbene Catalyzed Nucleophilic Silicon Transfer to Imines

(2014) Chunliang Zhao et al.   Asian Journal of Organic Chemistry

Synthesis and Suzuki-Miyaura Cross-Coupling of Enantioenriched Secondary Potassium β-Trifluoroboratoamides: Catalytic, Asymmetric Conjugate Addition of Bisboronic Acid and Tetrakis(dimethylamino)diboron to α,β-Unsaturated Carbonyl Compounds

(2013) Gary A. Molander et al.   ADVANCED SYNTHESIS & CATALYSIS

Copper-Catalyzed Addition of Nucleophilic Silicon to Aldehydes

(2013) Virginie Cirriez et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NHC–Cu(i) catalysed asymmetric conjugate silyl transfer to unsaturated lactones: application in kinetic resolution

(2013) Vittorio Pace et al.   CHEMICAL COMMUNICATIONS

Ni-Catalyzed Cascade Cyclization-Kumada Alkyl-Alkyl Cross-Coupling

(2013) Manuel Guisán-Ceinos et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Synthesis of α-Tri- and α-Tetrasubstituted Allylsilanes by Copper-Catalyzed Asymmetric Allylic Substitution of Allyl Phosphates with Silylboronates

(2013) Momotaro Takeda et al.   JOURNAL OF ORGANIC CHEMISTRY

Cu(I)–NHC Catalyzed Asymmetric Silyl Transfer to Unsaturated Lactams and Amides

(2013) Vittorio Pace et al.   ORGANIC LETTERS

Efficient Routes to Carbon–Silicon Bond Formation for the Synthesis of Silicon-Containing Peptides and Azasilaheterocycles

(2012) Geanna K. Min et al.   ACCOUNTS OF CHEMICAL RESEARCH

Activation of Si-Si Bonds for Copper(I)-Catalyzed Conjugate Silylation

(2012) Laura Iannazzo et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Organosilicon Molecules with Medicinal Applications

(2012) Annaliese K. Franz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Serine Protease Inhibition by a Silanediol Peptidomimetic

(2012) Swapnil Singh et al.   ORGANIC LETTERS

Copper(I)-Catalyzed Boryl Substitution of Unactivated Alkyl Halides

(2012) Hajime Ito et al.   ORGANIC LETTERS

NHC–Cu-Catalyzed Silyl Conjugate Additions to Acyclic and Cyclic Dienones and Dienoates. Efficient Site-, Diastereo- and Enantioselective Synthesis of Carbonyl-Containing Allylsilanes

(2012) Kang-sang Lee et al.   ORGANOMETALLICS

Alkylboronic Esters from Copper-Catalyzed Borylation of Primary and Secondary Alkyl Halides and Pseudohalides

(2011) Chu-Ting Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective formal hydration of α,β-unsaturated acceptors: asymmetric conjugate addition of silicon and boron nucleophiles

(2011) Eduard Hartmann et al.   CHEMICAL COMMUNICATIONS

Boron-containing inhibitors of synthetases

(2011) Stephen J. Baker et al.   CHEMICAL SOCIETY REVIEWS

Copper-Catalyzed 1,2-Addition of Nucleophilic Silicon to Aldehydes: Mechanistic Insight and Catalytic Systems

(2011) Christian Kleeberg et al.   CHEMISTRY-A EUROPEAN JOURNAL

Stereoconvergent Synthesis of Chiral Allylboronates from anE/ZMixture of Allylic Aryl Ethers Using a 6-NHC−Cu(I) Catalyst

(2011) Jin Kyoon Park et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed β-Boration of α,β-Unsaturated Carbonyl Compounds with Tetrahydroxydiborane

(2011) Gary A. Molander et al.   ORGANIC LETTERS

Activation of the Si−B Linkage: Copper-Catalyzed Addition of Nucleophilic Silicon to Imines

(2011) Devendra J. Vyas et al.   ORGANIC LETTERS

Enantioselective Conjugate Silyl Additions to Cyclic and Acyclic Unsaturated Carbonyls Catalyzed by Cu Complexes of Chiral N-Heterocyclic Carbenes

(2010) Kang-sang Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis oftrans-Aryl- and -Heteroaryl-Substituted Cyclopropylboronates by Copper(I)-Catalyzed Reactions of Allylic Phosphates with a Diboron Derivative

(2010) Chongmin Zhong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Differentially Protected Diboron for Regioselective Diboration of Alkynes: Internal-Selective Cross-Coupling of 1-Alkene-1,2-diboronic Acid Derivatives

(2010) Noriyuki Iwadate et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Allylboronates Bearing a Tertiary or Quaternary B-Substituted Stereogenic Carbon by NHC-Cu-Catalyzed Substitution Reactions

(2010) Aikomari Guzman-Martinez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Diboration of Ketones: Facile Synthesis of Tertiary α-Hydroxyboronate Esters

(2010) Melissa L. McIntosh et al.   ORGANIC LETTERS

C−H Activation for the Construction of C−B Bonds

(2009) Ibraheem A. I. Mkhalid et al.   CHEMICAL REVIEWS

Synthesis and applications of silicon-containing α-amino acids

(2009) Matthew Mortensen et al.   CHEMICAL SOCIETY REVIEWS

Catalytic β-Boration/Oxidation of 1-Azadienes

(2009) Cristina Sole et al.   Chemistry-An Asian Journal

Therapeutic potential of boron-containing compounds

(2009) Stephen J Baker et al.   Future Medicinal Chemistry

Efficient C−B Bond Formation Promoted by N-Heterocyclic Carbenes: Synthesis of Tertiary and Quaternary B-Substituted Carbons through Metal-Free Catalytic Boron Conjugate Additions to Cyclic and Acyclic α,β-Unsaturated Carbonyls

(2009) Kang-sang Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Cross-Coupling Reactions of Organosilanols and Their Salts: Practical Alternatives to Boron- and Tin-Based Methods

(2008) Scott E. Denmark et al.   ACCOUNTS OF CHEMICAL RESEARCH

Gold(0) Nanoparticles for Selective Catalytic Diboration

(2008) Jesus Ramírez et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Highly Enantioselective Carbenoid Insertion into SiH Bonds

(2008) Yong-Zhen Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION