Transitioning organic synthesis from organic solvents to water. What's your E Factor?

Reductive Dehalogenation of Arylhalides and Alkylhalides with Zinc in THF Saturated Aqueous Ammonium Chloride

(2015) Rahim Hekmatshoar et al.   JOURNAL OF THE CHINESE CHEMICAL SOCIETY

Reductive Cross-Coupling Reactions between Two Electrophiles

(2014) Christiane E. I. Knappke et al.   CHEMISTRY-A EUROPEAN JOURNAL

Installation of protected ammonia equivalents onto aromatic & heteroaromatic rings in water enabled by micellar catalysis

(2014) Nicholas A. Isley et al.   GREEN CHEMISTRY

“Nok”: A Phytosterol-Based Amphiphile Enabling Transition-Metal-Catalyzed Couplings in Water at Room Temperature

(2014) Piyatida Klumphu et al.   JOURNAL OF ORGANIC CHEMISTRY

Leveraging the Micellar Effect: Gold-Catalyzed Dehydrative Cyclizations in Water at Room Temperature

(2014) Stefan R. K. Minkler et al.   ORGANIC LETTERS

Air Oxidation of Primary Alcohols Catalyzed by Copper(I)/TEMPO. Preparation of 2-Amino-5-bromo-benzaldehyde

(2014)   ORGANIC SYNTHESES

Buchwald–Hartwig reactions in water using surfactants

(2014) Christophe Salomé et al.   TETRAHEDRON

Room Temperature Ambient Pressure (RTAP)-Hydroformylation in Water Using a Self-Assembling Ligand

(2013) Alexander T. Straub et al.   ADVANCED SYNTHESIS & CATALYSIS

On the Way Towards Greener Transition-Metal-Catalyzed Processes as Quantified by E Factors

(2013) Bruce H. Lipshutz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Directed Evolution by Using Iterative Saturation Mutagenesis Based on Multiresidue Sites

(2013) Loreto P. Parra et al.   CHEMBIOCHEM

Transition-metal-free oxidative trifluoromethylation of unsymmetrical biaryls with trifluoromethanesulfinate

(2013) Yu-Dong Yang et al.   CHEMICAL COMMUNICATIONS

Trifluoromethylation of heterocycles in water at room temperature

(2013) James C. Fennewald et al.   GREEN CHEMISTRY

“Click” and Olefin Metathesis Chemistry in Water at Room Temperature Enabled by Biodegradable Micelles

(2013) Bruce H. Lipshutz et al.   JOURNAL OF CHEMICAL EDUCATION

Mild Negishi Cross-Coupling Reactions Catalyzed by Acenaphthoimidazolylidene Palladium Complexes at Low Catalyst Loadings

(2013) Zelong Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Biocatalysis in Organic Chemistry and Biotechnology: Past, Present, and Future

(2013) Manfred T. Reetz   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transforming Suzuki–Miyaura Cross-Couplings of MIDA Boronates into a Green Technology: No Organic Solvents

(2013) Nicholas A. Isley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism of Copper(I)/TEMPO-Catalyzed Aerobic Alcohol Oxidation

(2013) Jessica M. Hoover et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemoselective Reductions of Nitroaromatics in Water at Room Temperature

(2013) Sean M. Kelly et al.   ORGANIC LETTERS

Chemoselective Transfer Hydrogenation to Nitroarenes Mediated by Cubane-Type Mo3S4Cluster Catalysts

(2012) Iván Sorribes et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A “Renaissance” in Radical Trifluoromethylation

(2012) Armido Studer   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Cross-Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize

(2012) Carin C. C. Johansson Seechurn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stille couplings in water at room temperature

(2012) Guo-ping Lu et al.   GREEN CHEMISTRY

C–C Bond Formation via Copper-Catalyzed Conjugate Addition Reactions to Enones in Water at Room Temperature

(2012) Bruce H. Lipshutz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Coupling Reactions of Alkyl Electrophiles, Including Unactivated Tertiary Halides, To Generate Carbon–Boron Bonds

(2012) Alexander S. Dudnik et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Merging Visible-Light Photocatalysis and Transition-Metal Catalysis in the Copper-Catalyzed Trifluoromethylation of Boronic Acids with CF3I

(2012) Yingda Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Green Chemistry is Good Process Chemistry

(2012) Trevor Laird   ORGANIC PROCESS RESEARCH & DEVELOPMENT

PhI(OAc)2-mediated oxidative trifluoromethylation of arenes with CF3SiMe3 under metal-free conditions

(2012) Xinyue Wu et al.   TETRAHEDRON LETTERS

Highly Selective Palladium-Catalyzed Direct CH α-Monoarylation of Carbonyl Compounds using Water Containing the Surfactant Polyoxyethylene-α-Tocopheryl Sebacate (PTS) as a Solvent

(2011) Marco Lessi et al.   ADVANCED SYNTHESIS & CATALYSIS

Current and new insights on phytosterol oxides in plant sterol-enriched food

(2011) Guadalupe García-Llatas et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Recyclable Catalysts for Palladium-Catalyzed Aminations of Aryl Halides

(2011) Andreas Dumrath et al.   CHEMISTRY-A EUROPEAN JOURNAL

Fe3O4 Nanoparticles: A Conveniently Reusable Catalyst for the Reduction of Nitroarenes Using Hydrazine Hydrate

(2011) Seyoung Kim et al.   Chemistry-An Asian Journal

Manipulating Micellar Environments for Enhancing Transition Metal-Catalyzed Cross-Couplings in Water at Room Temperature

(2011) Bruce H. Lipshutz et al.   JOURNAL OF ORGANIC CHEMISTRY

TPGS-750-M: A Second-Generation Amphiphile for Metal-Catalyzed Cross-Couplings in Water at Room Temperature

(2011) Bruce H. Lipshutz et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Practical Copper(I)/TEMPO Catalyst System for Chemoselective Aerobic Oxidation of Primary Alcohols

(2011) Jessica M. Hoover et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis

(2011) David A. Nagib et al.   NATURE

Radical reductions of alkyl halides bearing electron withdrawing groups with N-heterocyclic carbene boranes

(2011) Shau-Hua Ueng et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Organozinc Chemistry Enabled by Micellar Catalysis. Palladium-Catalyzed Cross-Couplings between Alkyl and ArylBromidesin Water at Room Temperature

(2011) Christophe Duplais et al.   ORGANOMETALLICS

Innate C-H trifluoromethylation of heterocycles

(2011) Y. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ionic Liquid-Supported Synthesis of Sulfonamides and Carboxamides

(2011) Manoj Kumar Muthayala et al.   ACS Combinatorial Science

Selective hydrogenation of functionalized nitroarenes under mild conditions

(2011) Valerica Pandarus et al.   Catalysis Science & Technology

Imaging of Self-Assembled Structures: Interpretation of TEM and Cryo-TEM Images

(2010) Heiner Friedrich et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A P,N-Ligand for Palladium-Catalyzed Ammonia Arylation: Coupling of Deactivated Aryl Chlorides, Chemoselective Arylations, and Room Temperature Reactions

(2010) Rylan J. Lundgren et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Efficient Low-Temperature Stille-Migita Cross-Coupling Reaction for Heteroaromatic Compounds by Pd-PEPPSI-IPent

(2010) Meenakshi Dowlut et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed Direct Arylation of 4-Chromanones: Selective Synthesis of Racemic Isoflavanones and 3,3-Diaryl-4-chromanones

(2010) Fabio Bellina et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Development of safe and scalable continuous-flow methods for palladium-catalyzed aerobic oxidation reactions

(2010) Xuan Ye et al.   GREEN CHEMISTRY

Miyaura Borylations of Aryl Bromides in Water at Room Temperature

(2010) Bruce H. Lipshutz et al.   ISRAEL JOURNAL OF CHEMISTRY

The Palladium-Catalyzed Trifluoromethylation of Aryl Chlorides

(2010) E. J. Cho et al.   SCIENCE

Aerobic Oxidation of Benzylic Alcohols in Water by 2,2,6,6-Tetramethylpiperidine-1-oxyl (TEMPO)/Copper(II) 2-N-Arylpyrrolecarbaldimino Complexes

(2009) Paweł J. Figiel et al.   ADVANCED SYNTHESIS & CATALYSIS

A Facile Route to Aryl Boronates: Room-Temperature, Copper-Catalyzed Borylation of Aryl Halides with Alkoxy Diboron Reagents

(2009) Christian Kleeberg et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient copper-catalyzed coupling of aryl chlorides, bromides and iodides with aqueous ammonia

(2009) Hanhui Xu et al.   CHEMICAL COMMUNICATIONS

Negishi Cross-Couplings Compatible with Unprotected Amide Functions

(2009) Georg Manolikakes et al.   CHEMISTRY-A EUROPEAN JOURNAL

Room-Temperature Pd-Catalyzed Amidation of Aryl Bromides Usingtert-Butyl Carbamate

(2009) Swapna Bhagwanth et al.   JOURNAL OF ORGANIC CHEMISTRY

Electron-Transfer Photoredox Catalysis: Development of a Tin-Free Reductive Dehalogenation Reaction

(2009) Jagan M. R. Narayanam et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Zn-Mediated, Pd-Catalyzed Cross-Couplings in Water at Room TemperatureWithoutPrior Formation of Organozinc Reagents

(2009) Arkady Krasovskiy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium- and Nickel-Catalyzed Cross-Couplings of Unsaturated Halides Bearing Relatively Acidic Protons with Organozinc Reagents

(2008) Georg Manolikakes et al.   JOURNAL OF ORGANIC CHEMISTRY

Phytosterols: physiologic and metabolic aspects related to cholesterol-lowering properties

(2008) Gemma Brufau et al.   NUTRITION RESEARCH

Negishi Cross-Couplings of Unsaturated Halides Bearing Relatively Acidic Hydrogen Atoms with Organozinc Reagents

(2008) Georg Manolikakes et al.   ORGANIC LETTERS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS