Antagonistic pleiotropy conceals molecular adaptations in changing environments

Patterns and Mechanisms of Diminishing Returns from Beneficial Mutations

(2019) Xinzhu Wei et al.   MOLECULAR BIOLOGY AND EVOLUTION

Yeast Spontaneous Mutation Rate and Spectrum Vary with Environment

(2019) Haoxuan Liu et al.   CURRENT BIOLOGY

Spontaneous Changes in Ploidy Are Common in Yeast

(2018) Yaniv Harari et al.   CURRENT BIOLOGY

The Neutral Theory in Light of Natural Selection

(2018) Andrew D Kern et al.   MOLECULAR BIOLOGY AND EVOLUTION

The genome-wide rate and spectrum of spontaneous mutations differ between haploid and diploid yeast

(2018) Nathaniel P. Sharp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antagonistic pleiotropy for carbon use is rare in new mutations

(2018) Mrudula Sane et al.   EVOLUTION

Deciphering the Genic Basis of Yeast Fitness Variation by Simultaneous Forward and Reverse Genetics

(2017) Calum J. Maclean et al.   MOLECULAR BIOLOGY AND EVOLUTION

The emergence of performance trade-offs during local adaptation: insights from experimental evolution

(2017) Lisa M. Bono et al.   MOLECULAR ECOLOGY

The dynamics of molecular evolution over 60,000 generations

(2017) Benjamin H. Good et al.   NATURE

Diminishing-returns epistasis decreases adaptability along an evolutionary trajectory

(2017) Andrea Wünsche et al.   Nature Ecology & Evolution

The Genomic Architecture of Interactions Between Natural Genetic Polymorphisms and Environments in Yeast Growth

(2016) Xinzhu Wei et al.   GENETICS

Tempo and mode of genome evolution in a 50,000-generation experiment

(2016) Olivier Tenaillon et al.   NATURE

The Genomic Architecture of Interactions Between Natural Genetic Polymorphisms and Environments in Yeast Growth

(2016) Xinzhu Wei et al.   GENETICS

Quantitative evolutionary dynamics using high-resolution lineage tracking

(2015) Sasha F. Levy et al.   NATURE

The spectrum of adaptive mutations in experimental evolution

(2014) Gregory I. Lang et al.   GENOMICS

Global epistasis makes adaptation predictable despite sequence-level stochasticity

(2014) S. Kryazhimskiy et al.   SCIENCE

Why Time Matters: Codon Evolution and the Temporal Dynamics of dN/dS

(2013) Carina F. Mugal et al.   MOLECULAR BIOLOGY AND EVOLUTION

Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations

(2013) Gregory I. Lang et al.   NATURE

Finding the sources of missing heritability in a yeast cross

(2013) Joshua S. Bloom et al.   NATURE

The Molecular Diversity of Adaptive Convergence

(2012) O. Tenaillon et al.   SCIENCE

The Genomic Landscape and Evolutionary Resolution of Antagonistic Pleiotropy in Yeast

(2012) Wenfeng Qian et al.   Cell Reports

The pleiotropic structure of the genotype–phenotype map: the evolvability of complex organisms

(2011) Günter P. Wagner et al.   NATURE REVIEWS GENETICS

The Impact of Recombination on dN/dS within Recently Emerged Bacterial Clones

(2011) Santiago Castillo-Ramírez et al.   PLoS Pathogens

The Neutral Theory of Molecular Evolution in the Genomic Era

(2010) Masatoshi Nei et al.   Annual Review of Genomics and Human Genetics

Many Possible Worlds: Expanding the Ecological Scenarios in Experimental Evolution

(2010) Sinéad Collins   Evolutionary Biology

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Fitness flux and ubiquity of adaptive evolution

(2010) V. Mustonen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic patterns of pleiotropy and the evolution of complexity

(2010) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Nonlinear Dynamics of Nonsynonymous (dN) and Synonymous (dS) Substitution Rates Affects Inference of Selection

(2009) Jochen B. W. Wolf et al.   Genome Biology and Evolution

The Population Genetics of dN/dS

(2008) Sergey Kryazhimskiy et al.   PLoS Genetics