The genome-wide rate and spectrum of spontaneous mutations differ between haploid and diploid yeast

Altered access to beneficial mutations slows adaptation and biases fixed mutations in diploids

(2018) Daniel A. Marad et al.   Nature Ecology & Evolution

Fitness change in relation to mutation number in spontaneous mutation accumulation lines of Chlamydomonas reinhardtii

(2017) Susanne A. Kraemer et al.   EVOLUTION

Reduced mutation rate in exons due to differential mismatch repair

(2017) Joan Frigola et al.   NATURE GENETICS

The dynamic three-dimensional organization of the diploid yeast genome

(2017) Seungsoo Kim et al.   eLife

Low Genetic Quality Alters Key Dimensions of the Mutational Spectrum

(2016) Nathaniel P. Sharp et al.   PLOS BIOLOGY

The Spontaneous Mutation Rate in the Fission YeastSchizosaccharomyces pombe

(2015) Ashley Farlow et al.   GENETICS

Extensive de novo mutation rate variation between individuals and across the genome ofChlamydomonas reinhardtii

(2015) Rob W. Ness et al.   GENOME RESEARCH

Polyploidy can drive rapid adaptation in yeast

(2015) Anna M. Selmecki et al.   NATURE

Genome-Wide Estimates of Mutation Rates and Spectrum in Schizosaccharomyces pombe Indicate CpG Sites are Highly Mutagenic Despite the Absence of DNA Methylation

(2015) Megan G. Behringer et al.   G3-Genes Genomes Genetics

The Spontaneous Mutation Rate in the Fission YeastSchizosaccharomyces pombe

(2015) Ashley Farlow et al.   GENETICS

Cytosine DNA Methylation Is Found in Drosophila melanogaster but Absent in Saccharomyces cerevisiae, Schizosaccharomyces pombe, and Other Yeast Species

(2014) Floriana Capuano et al.   ANALYTICAL CHEMISTRY

Mechanisms and Regulation of Mitotic Recombination in Saccharomyces cerevisiae

(2014) L. S. Symington et al.   GENETICS

Precise estimates of mutation rate and spectrum in yeast

(2014) Y. O. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutational landscape of yeast mutator strains

(2014) Alexandre Serero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene Copy-Number Variation in Haploid and Diploid Strains of the Yeast Saccharomyces cerevisiae

(2013) H. Zhang et al.   GENETICS

The dynamics of genome replication using deep sequencing

(2013) Carolin A. Müller et al.   NUCLEIC ACIDS RESEARCH

Bridge-Induced Chromosome Translocation in Yeast Relies upon a Rad54/Rdh54-Dependent, Pol32-Independent Pathway

(2013) Valentina Tosato et al.   PLoS One

Widespread Existence of Cytosine Methylation in Yeast DNA Measured by Gas Chromatography/Mass Spectrometry

(2012) Yang Tang et al.   ANALYTICAL CHEMISTRY

Mutational effects depend on ploidy level: all else is not equal

(2012) A. C. Gerstein   Biology Letters

The Evolution of Low Mutation Rates in Experimental Mutator Populations of Saccharomyces cerevisiae

(2012) Michael J. McDonald et al.   CURRENT BIOLOGY

Pervasive Multinucleotide Mutational Events in Eukaryotes

(2011) Daniel R. Schrider et al.   CURRENT BIOLOGY

Ploidy Dictates Repair Pathway Choice under DNA Replication Stress

(2011) X. C. Li et al.   GENETICS

Mutation Rates across Budding Yeast Chromosome VI Are Correlated with Replication Timing

(2011) Gregory I. Lang et al.   Genome Biology and Evolution

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Cryptic Fitness Advantage: Diploids Invade Haploid Populations Despite Lacking Any Apparent Advantage as Measured by Standard Fitness Assays

(2011) Aleeza C. Gerstein et al.   PLoS One

Outcrossing, mitotic recombination, and life-history trade-offs shape genome evolution inSaccharomyces cerevisiae

(2011) Paul M. Magwene et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A High Frequency of Beneficial Mutations Across Multiple Fitness Components in Saccharomyces cerevisiae

(2010) D. W. Hall et al.   GENETICS

Haploids adapt faster than diploids across a range of environments

(2010) A. C. GERSTEIN et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Yeast evolutionary genomics

(2010) Bernard Dujon   NATURE REVIEWS GENETICS

Chromosome arm length and nuclear constraints determine the dynamic relationship of yeast subtelomeres

(2010) P. Therizols et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromosome rearrangements and aneuploidy in yeast strains lacking both Tel1p and Mec1p reflect deficiencies in two different mechanisms

(2010) J. L. McCulley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution of the mutation rate

(2010) Michael Lynch   TRENDS IN GENETICS

The Baker's Yeast Diploid Genome Is Remarkably Stable in Vegetative Growth and Meiosis

(2010) K. T. Nishant et al.   PLoS Genetics

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Ploidy and the Causes of Genomic Evolution

(2009) A. C. Gerstein et al.   JOURNAL OF HEREDITY

Comprehensive polymorphism survey elucidates population structure of Saccharomyces cerevisiae

(2009) Joseph Schacherer et al.   NATURE

The evolution of haploidy and diploidy

(2008) Sarah P. Otto et al.   CURRENT BIOLOGY

Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast

(2008) Lyris M. F. de Godoy et al.   NATURE

A genome-wide view of the spectrum of spontaneous mutations in yeast

(2008) M. Lynch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Double-strand breaks associated with repetitive DNA can reshape the genome

(2008) J. L. Argueso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Repertoire and Dynamics of Evolutionary Adaptations to Controlled Nutrient-Limited Environments in Yeast

(2008) David Gresham et al.   PLoS Genetics