Natural Compounds in Prostate Cancer Prevention and Treatment: Mechanisms of Action and Molecular Targets
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Title
Natural Compounds in Prostate Cancer Prevention and Treatment: Mechanisms of Action and Molecular Targets
Authors
Keywords
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Journal
Cells
Volume 9, Issue 2, Pages 460
Publisher
MDPI AG
Online
2020-02-25
DOI
10.3390/cells9020460
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Note: Only part of the references are listed.- Effects of Berberine and Its Derivatives on Cancer: A Systems Pharmacology Review
- (2020) Chaohe Zhang et al. Frontiers in Pharmacology
- The emerging role of paraptosis in tumor cell biology: Perspectives for cancer prevention and therapy with natural compounds
- (2020) Fabrizio Fontana et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Tocotrienols and Cancer: From the State of the Art to Promising Novel Patents
- (2019) Fabrizio Fontana et al. Recent Patents on Anti-Cancer Drug Discovery
- A randomized, double‐blind, placebo‐controlled trial to evaluate the role of curcumin in prostate cancer patients with intermittent androgen deprivation
- (2019) Young Hyo Choi et al. PROSTATE
- Genistein treatment duration effects biomarkers of cell motility in human prostate
- (2019) Hu Zhang et al. PLoS One
- Green tea-induced epigenetic reactivation of tissue inhibitor of matrix metalloproteinase-3 suppresses prostate cancer progression through histone-modifying enzymes
- (2019) Gauri Deb et al. MOLECULAR CARCINOGENESIS
- Role of Endoplasmic Reticulum Stress in the Anticancer Activity of Natural Compounds
- (2019) Patrizia Limonta et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A Review of Curcumin and Its Derivatives as Anticancer Agents
- (2019) Mhd Tomeh et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- δ‐Tocotrienol induces apoptosis, involving endoplasmic reticulum stress and autophagy, and paraptosis in prostate cancer cells
- (2019) Fabrizio Fontana et al. CELL PROLIFERATION
- Treatment of Advanced Prostate Cancer
- (2019) Min Yuen Teo et al. Annual Review of Medicine
- Luteolin, a flavonoid, as an anticancer agent: A review
- (2019) Muhammad Imran et al. BIOMEDICINE & PHARMACOTHERAPY
- Midkine silencing enhances the anti–prostate cancer stem cell activity of the flavone apigenin: cooperation on signaling pathways regulated by ERK, p38, PTEN, PARP, and NF-κB
- (2019) Suat Erdogan et al. INVESTIGATIONAL NEW DRUGS
- Modulation of miR‐34a in curcumin‐induced antiproliferation of prostate cancer cells
- (2019) Mingming Zhu et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis
- (2019) Ming-Hsien Chien et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Phytochemicals in Prostate Cancer: From Bioactive Molecules to Upcoming Therapeutic Agents
- (2019) Salehi et al. Nutrients
- Ginsenoside Rb1 inhibits vascular calcification as a selective androgen receptor modulator
- (2019) Michiko Nanao-Hamai et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Molecular Mechanisms of Action of Genistein in Cancer: Recent Advances
- (2019) Hardeep Singh Tuli et al. Frontiers in Pharmacology
- Modulation of AKR1C2 by curcumin decreases testosterone production in prostate cancer
- (2018) Hisamitsu Ide et al. CANCER SCIENCE
- Prostate cancer chemoprevention by sulforaphane in a preclinical mouse model is associated with inhibition of fatty acid metabolism
- (2018) Krishna B Singh et al. CARCINOGENESIS
- Ginsenoside Rh2 inhibits prostate cancer cell growth through suppression of microRNA-4295 that activates CDKN1A
- (2018) Qiruo Gao et al. CELL PROLIFERATION
- Molecular targets of celastrol in cancer: Recent trends and advancements
- (2018) Dharambir Kashyap et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Curcumin Suppresses In Vitro Proliferation and Invasion of Human Prostate Cancer Stem Cells by Modulating DLK1-DIO3 Imprinted Gene Cluster MicroRNAs
- (2018) Hu Zhang et al. Genetic Testing and Molecular Biomarkers
- Circulating isoflavone and lignan concentrations and prostate cancer risk: A meta-analysis of individual participant data from seven prospective studies including 2828 cases and 5593 controls
- (2018) Aurora Perez-Cornago et al. INTERNATIONAL JOURNAL OF CANCER
- The biology and role of CD44 in cancer progression: therapeutic implications
- (2018) Chen Chen et al. Journal of Hematology & Oncology
- Prostate Cancer Stem Cells: Current Understanding
- (2018) Sergej Skvortsov et al. STEM CELLS
- Quercetin inhibits prostate cancer by attenuating cell survival and inhibiting anti-apoptotic pathways
- (2018) Ashley B. Ward et al. World Journal of Surgical Oncology
- New highlights on the health-improving effects of sulforaphane
- (2018) Alfredo Briones-Herrera et al. Food & Function
- Luteolin attenuates Wnt signaling via upregulation of FZD6 to suppress prostate cancer stemness revealed by comparative proteomics
- (2018) Kun Han et al. Scientific Reports
- Tannic Acid Induces Endoplasmic Reticulum Stress-Mediated Apoptosis in Prostate Cancer
- (2018) Prashanth Nagesh et al. Cancers
- Midkine downregulation increases the efficacy of quercetin on prostate cancer stem cell survival and migration through PI3K/AKT and MAPK/ERK pathway
- (2018) Suat Erdogan et al. BIOMEDICINE & PHARMACOTHERAPY
- Anticancer properties of tocotrienols: A review of cellular mechanisms and molecular targets
- (2018) Marina Montagnani Marelli et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Anticancer potential of quercetin: A comprehensive review
- (2018) Abdur Rauf et al. PHYTOTHERAPY RESEARCH
- Resveratrol integrates metabolic and growth effects in PC3 prostate cancer cells‑involvement of prolyl hydroxylase and hypoxia inducible factor‑1
- (2018) Joao Fonseca et al. Oncology Letters
- New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
- (2018) Anushka Dongre et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Randomized, double-blind, placebo-controlled phase II trial of nanocurcumin in prostate cancer patients undergoing radiotherapy
- (2018) Afshin Saadipoor et al. PHYTOTHERAPY RESEARCH
- Resveratrol Induces Apoptosis in Murine Prostate Cancer Cells via Hypoxia-Inducible Factor 1-alpha (HIF-1α)/Reactive Oxygen Species (ROS)/P53 Signaling
- (2018) Delong Wang et al. MEDICAL SCIENCE MONITOR
- Curcumin suppresses proliferation and in vitro invasion of human prostate cancer stem cells by ceRNA effect of miR-145 and lncRNA-ROR
- (2017) Te Liu et al. GENE
- WNT signalling in prostate cancer
- (2017) Virginia Murillo-Garzón et al. Nature Reviews Urology
- Multimodal actions of the phytochemical sulforaphane suppress both AR and AR-V7 in 22Rv1 cells: Advocating a potent pharmaceutical combination against castration-resistant prostate cancer
- (2017) Namrata Khurana et al. ONCOLOGY REPORTS
- Reduced prostate cancer risk with green tea and epigallocatechin 3-gallate intake among Hong Kong Chinese men
- (2017) P M Y Lee et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Celastrol, an active constituent of the TCM plant Tripterygium wilfordii Hook.f., inhibits prostate cancer bone metastasis
- (2017) K Kuchta et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Prolonged exposure of resveratrol induces reactive superoxide species–independent apoptosis in murine prostate cells
- (2017) Sanjay Kumar et al. TUMOR BIOLOGY
- Structure of the homodimeric androgen receptor ligand-binding domain
- (2017) Marta Nadal et al. Nature Communications
- Curcumin induces apoptosis and protective autophagy in castration-resistant prostate cancer cells through iron chelation
- (2017) Chunguang Yang et al. Drug Design Development and Therapy
- Resveratrol enhances polyubiquitination-mediated ARV7 degradation in prostate cancer cells
- (2017) Sarah Wilson et al. Oncotarget
- Androgen Signaling in Prostate Cancer
- (2017) Charles Dai et al. Cold Spring Harbor Perspectives in Medicine
- The role of Sulforaphane in cancer chemoprevention and health benefits: a mini-review
- (2017) Reza Bayat Mokhtari et al. Journal of Cell Communication and Signaling
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- (2017) Balaraman Kalyanaraman Redox Biology
- Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015
- (2017) et al. JAMA Oncology
- The Metabolic Phenotype of Prostate Cancer
- (2017) Eric Eidelman et al. Frontiers in Oncology
- Targeting multiple pro-apoptotic signaling pathways with curcumin in prostate cancer cells
- (2017) Mariela Rivera et al. PLoS One
- Dietary Flavonoids Luteolin and Quercetin Suppressed Cancer Stem Cell Properties and Metastatic Potential of Isolated Prostate Cancer Cells
- (2016) PEI-HSUN TSAI et al. ANTICANCER RESEARCH
- Silibinin induces mitochondrial NOX4-mediated endoplasmic reticulum stress response and its subsequent apoptosis
- (2016) Sang-Hun Kim et al. BMC CANCER
- Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases
- (2016) Ajaikumar B Kunnumakkara et al. BRITISH JOURNAL OF PHARMACOLOGY
- Dietary flavonoid fisetin increases abundance of high-molecular-mass hyaluronan conferring resistance to prostate oncogenesis
- (2016) Rahul K. Lall et al. CARCINOGENESIS
- Targeting the NF-κB pathway in prostate cancer: a promising therapeutic approach?
- (2016) Daniela Verzella et al. CURRENT DRUG TARGETS
- Sulforaphane increases the efficacy of anti-androgens by rapidly decreasing androgen receptor levels in prostate cancer cells
- (2016) Namrata Khurana et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Relationship of serum levels and dietary intake of isoflavone, and the novel bacterium Slackia sp. strain NATTS with the risk of prostate cancer: a case–control study among Japanese men
- (2016) Yoshie Nagata et al. INTERNATIONAL UROLOGY AND NEPHROLOGY
- Sulforaphane Inhibits c-Myc-Mediated Prostate Cancer Stem-Like Traits
- (2016) Avani R. Vyas et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Calcitriol and 20( S )-protopanaxadiol synergistically inhibit growth and induce apoptosis in human prostate cancer cells
- (2016) Mohamed Ben-Eltriki et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial
- (2016) Nicholas D James et al. LANCET
- The flavonoid apigenin reduces prostate cancer CD44 + stem cell survival and migration through PI3K/Akt/NF-κB signaling
- (2016) Suat Erdogan et al. LIFE SCIENCES
- Silibinin inhibits hypoxia-induced HIF-1α-mediated signaling, angiogenesis and lipogenesis in prostate cancer cells: In vitro evidence and in vivo functional imaging and metabolomics
- (2016) Gagan Deep et al. MOLECULAR CARCINOGENESIS
- Dietary flavonoid fisetin for cancer prevention and treatment
- (2016) Rahul K. Lall et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Curcumin and Health
- (2016) Mario Pulido-Moran et al. MOLECULES
- Mechanisms and regulation of endothelial VEGF receptor signalling
- (2016) Michael Simons et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Effect of Curcumin Supplementation During Radiotherapy on Oxidative Status of Patients with Prostate Cancer: A Double Blinded, Randomized, Placebo-Controlled Study
- (2016) Jalal Hejazi et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Sulforaphane-cysteine suppresses invasion via downregulation of galectin-1 in human prostate cancer DU145 and PC3 cells
- (2016) Hua Tian et al. ONCOLOGY REPORTS
- Paraptosis in the anti-cancer arsenal of natural products
- (2016) Dongjoo Lee et al. PHARMACOLOGY & THERAPEUTICS
- Berberis Vulgarisand Berberine: An Update Review
- (2016) Mohsen Imenshahidi et al. PHYTOTHERAPY RESEARCH
- Bioactive natural products for chemoprevention and treatment of castration-resistant prostate cancer
- (2016) Georgios Kallifatidis et al. SEMINARS IN CANCER BIOLOGY
- Quercetin modulates Wnt signaling components in prostate cancer cell line by inhibiting cell viability, migration, and metastases
- (2016) Meghna M. Baruah et al. TUMOR BIOLOGY
- Luteolin inhibited proliferation and induced apoptosis of prostate cancer cells through miR-301
- (2016) Kun Han et al. OncoTargets and Therapy
- Dietary pterostilbene is a novel MTA1-targeted chemopreventive and therapeutic agent in prostate cancer
- (2016) Swati Dhar et al. Oncotarget
- Silibinin: a potential old drug for cancer therapy
- (2016) Xing-Xing Zhu et al. Expert Review of Clinical Pharmacology
- Autophagy inhibition enhances silibinin-induced apoptosis by regulating reactive oxygen species production in human prostate cancer PC-3 cells
- (2015) Sang-Hun Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inhibiting inducible miR-223 further reduces viable cells in human cancer cell lines MCF-7 and PC3 treated by celastrol
- (2015) Lu Cao et al. BMC CANCER
- Luteolin as an anti-inflammatory and neuroprotective agent: A brief review
- (2015) Seyed Fazel Nabavi et al. BRAIN RESEARCH BULLETIN
- Randomized, Placebo-Controlled Trial of Green Tea Catechins for Prostate Cancer Prevention
- (2015) N. B. Kumar et al. Cancer Prevention Research
- Effect of Sulforaphane in Men with Biochemical Recurrence after Radical Prostatectomy
- (2015) B. G. Cipolla et al. Cancer Prevention Research
- Berberine Inhibits the Metastatic Ability of Prostate Cancer Cells by Suppressing Epithelial-to-Mesenchymal Transition (EMT)-Associated Genes with Predictive and Prognostic Relevance
- (2015) Chia-Hung Liu et al. International Journal of Medical Sciences
- Plasma genistein and risk of prostate cancer in Chinese population
- (2015) Yishuo Wu et al. INTERNATIONAL UROLOGY AND NEPHROLOGY
- Resveratrol activates autophagic cell death in prostate cancer cells via downregulation of STIM1 and the mTOR pathway
- (2015) Senthil Selvaraj et al. MOLECULAR CARCINOGENESIS
- Analysis of autophagic flux in response to sulforaphane in metastatic prostate cancer cells
- (2015) Gregory W. Watson et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Chemohormonal Therapy in Metastatic Hormone-Sensitive Prostate Cancer
- (2015) Christopher J. Sweeney et al. NEW ENGLAND JOURNAL OF MEDICINE
- Quercetin inhibits angiogenesis through thrombospondin-1 upregulation to antagonize human prostate cancer PC-3 cell growth in vitro and in vivo
- (2015) FEIYA YANG et al. ONCOLOGY REPORTS
- Sulforaphane inhibits invasion by phosphorylating ERK1/2 to regulate E-cadherin and CD44v6 in human prostate cancer DU145 cells
- (2015) XIAOHUI PENG et al. ONCOLOGY REPORTS
- A phase I study of muscadine grape skin extract in men with biochemically recurrent prostate cancer: Safety, tolerability, and dose determination
- (2015) Channing J. Paller et al. PROSTATE
- Resveratrol reduces the levels of circulating androgen precursors but has no effect on, testosterone, dihydrotestosterone, PSA levels or prostate volume. A 4-month randomised trial in middle-aged men
- (2015) Thomas Nordstrøm Kjaer et al. PROSTATE
- Curcumin mediates reversion of HGF-induced epithelial-mesenchymal transition via inhibition of c-Met expression in DU145 cells
- (2015) HUI-JUN HU et al. Oncology Letters
- Resveratrol and pterostilbene epigenetically restore PTEN expression by targeting oncomiRs of the miR-17 family in prostate cancer
- (2015) Swati Dhar et al. Oncotarget
- Nonautophagic cytoplasmic vacuolation death induction in human PC-3M prostate cancer by curcumin through reactive oxygen species -mediated endoplasmic reticulum stress
- (2015) Wei-Jiunn Lee et al. Scientific Reports
- Celastrol Induces Autophagy by Targeting AR/miR-101 in Prostate Cancer Cells
- (2015) Jianquan Guo et al. PLoS One
- YB-1 expression promotes epithelial-to-mesenchymal transition in prostate cancer that is inhibited by a small molecule fisetin
- (2015) Mohammad Imran Khan et al. Oncotarget
- Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1
- (2015) Dhanya K. Nambiar et al. Oncotarget
- Oncogenic functions of IGF1R and INSR in prostate cancer include enhanced tumor growth, cell migration and angiogenesis
- (2015) Isabel Heidegger et al. Oncotarget
- PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance
- (2014) AndrewC Hsieh et al. ASIAN JOURNAL OF ANDROLOGY
- Mitochondrial protein cyclophilin-D-mediated programmed necrosis attributes to berberine-induced cytotoxicity in cultured prostate cancer cells
- (2014) Long-yang Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Resveratrol Inhibits IL-6-Induced Transcriptional Activity of AR and STAT3 in Human Prostate Cancer LNCaP-FGC Cells
- (2014) Mee-Hyun Lee et al. Biomolecules & Therapeutics
- Genistein downregulates onco-miR-1260b and upregulates sFRP1 and Smad4 via demethylation and histone modification in prostate cancer cells
- (2014) H Hirata et al. BRITISH JOURNAL OF CANCER
- Regulation of GLUT Transporters by Flavonoids in Androgen-Sensitive and -Insensitive Prostate Cancer Cells
- (2014) Pedro Gonzalez-Menendez et al. ENDOCRINOLOGY
- A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer
- (2014) Joshi J. Alumkal et al. INVESTIGATIONAL NEW DRUGS
- Quercetin reverses EGF-induced epithelial to mesenchymal transition and invasiveness in prostate cancer (PC-3) cell line via EGFR/PI3K/Akt pathway
- (2014) Firdous Ahmad Bhat et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Resveratrol Inhibits Hypoxia-Inducible Factor-1^|^alpha;-Mediated Androgen Receptor Signaling and Represses Tumor Progression in Castration-Resistant Prostate Cancer
- (2014) Takakazu MITANI et al. JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
- Apigenin inhibits migration and invasion via modulation of epithelial mesenchymal transition in prostate cancer
- (2014) YI ZHU et al. Molecular Medicine Reports
- Silibinin inhibits fibronectin induced motility, invasiveness and survival in human prostate carcinoma PC3 cells via targeting integrin signaling
- (2014) Gagan Deep et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- 20(S)-Protopanaxadiol Inhibition of Progression and Growth of Castration-Resistant Prostate Cancer
- (2014) Bo Cao et al. PLoS One
- Honokiol activates reactive oxygen species-mediated cytoprotective autophagy in human prostate cancer cells
- (2014) Eun-Ryeong Hahm et al. PROSTATE
- Management of Bone Metastases in Patients with Castration-Resistant Prostate Cancer
- (2014) Richard Cathomas et al. UROLOGIA INTERNATIONALIS
- Quercetin, a natural dietary flavonoid, acts as a chemopreventive agent against prostate cancer in an in vivo model by inhibiting the EGFR signaling pathway
- (2014) A. B. Firdous et al. Food & Function
- Celastrol inhibits TGF-β1-induced epithelial–mesenchymal transition by inhibiting Snail and regulating E-cadherin expression
- (2013) Hyereen Kang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The fat side of prostate cancer
- (2013) Giorgia Zadra et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Curcumin-Targeting Pericellular Serine Protease Matriptase Role in Suppression of Prostate Cancer Cell Invasion, Tumor Growth, and Metastasis
- (2013) T.-S. Cheng et al. Cancer Prevention Research
- Apigenin inhibits prostate cancer progression in TRAMP mice via targeting PI3K/Akt/FoxO pathway
- (2013) S. Shukla et al. CARCINOGENESIS
- Crosstalk from survival to necrotic death coexists in DU-145 cells by curcumin treatment
- (2013) Dongxu Kang et al. CELLULAR SIGNALLING
- Mechanisms of Androgen Receptor Activation in Castration-Resistant Prostate Cancer
- (2013) Nima Sharifi ENDOCRINOLOGY
- Thrombospondin-1 Is a Putative Target Gene of Runx2 and Runx3
- (2013) Xiuming Shi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Hedgehog Signaling in Prostate Cancer and Its Therapeutic Implication
- (2013) Annelies Gonnissen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Epigallocatechin-3-gallate promotes apoptosis and expression of the caspase 9a splice variant in PC3 prostate cancer cells
- (2013) RACHEL M. HAGEN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Apigenin inhibits TGF-β-induced VEGF expression in human prostate carcinoma cells via a Smad2/3- and Src-dependent mechanism
- (2013) Salida Mirzoeva et al. MOLECULAR CARCINOGENESIS
- Luteolin Inhibits Human Prostate Tumor Growth by Suppressing Vascular Endothelial Growth Factor Receptor 2-Mediated Angiogenesis
- (2013) Poyil Pratheeshkumar et al. PLoS One
- Genistein Up-Regulates Tumor Suppressor MicroRNA-574-3p in Prostate Cancer
- (2013) Takeshi Chiyomaru et al. PLoS One
- Celastrol Suppresses Tumor Cell Growth through Targeting an AR-ERG-NF-κB Pathway in TMPRSS2/ERG Fusion Gene Expressing Prostate Cancer
- (2013) Longjiang Shao et al. PLoS One
- Genistein Inhibits Prostate Cancer Cell Growth by Targeting miR-34a and Oncogenic HOTAIR
- (2013) Takeshi Chiyomaru et al. PLoS One
- Differential Effects of Genistein on Prostate Cancer Cells Depend on Mutational Status of the Androgen Receptor
- (2013) Abeer M. Mahmoud et al. PLoS One
- Honokiol inhibits androgen receptor activity in prostate cancer cells
- (2013) Eun-Ryeong Hahm et al. PROSTATE
- Silibinin – A Promising New Treatment for Cancer
- (2012) Catherine Wing Ying Cheung et al. Anti-Cancer Agents in Medicinal Chemistry
- Expression of glucose transporters in cancers
- (2012) Leszek Szablewski BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Prediagnostic concentrations of plasma genistein and prostate cancer risk in 1,605 men with prostate cancer and 1,697 matched control participants in EPIC
- (2012) Ruth C. Travis et al. CANCER CAUSES & CONTROL
- Genistein inhibits the stemness properties of prostate cancer cells through targeting Hedgehog–Gli1 pathway
- (2012) Linlin Zhang et al. CANCER LETTERS
- Silibinin inhibits Wnt/β-catenin signaling by suppressing Wnt co-receptor LRP6 expression in human prostate and breast cancer cells
- (2012) Wenyan Lu et al. CELLULAR SIGNALLING
- The roles of endoplasmic reticulum stress and mitochondrial apoptotic signaling pathway in quercetin-mediated cell death of human prostate cancer PC-3 cells
- (2012) Kuo-Ching Liu et al. ENVIRONMENTAL TOXICOLOGY
- Ginsenoside Rg3 attenuates cell migration via inhibition of aquaporin 1 expression in PC-3M prostate cancer cells
- (2012) Xue-Yang Pan et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- 20(S)-protopanaxadiol-aglycone downregulation of the full-length and splice variants of androgen receptor
- (2012) Bo Cao et al. INTERNATIONAL JOURNAL OF CANCER
- The High and Low Molecular Weight Forms of Hyaluronan Have Distinct Effects on CD44 Clustering
- (2012) Cuixia Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Stepwise androgen receptor dimerization
- (2012) M. E. van Royen et al. JOURNAL OF CELL SCIENCE
- Paraptosis accompanied by autophagy and apoptosis was induced by celastrol, a natural compound with influence on proteasome, ER stress and Hsp90
- (2012) Wen-Bo Wang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Androgen action and metabolism in prostate cancer
- (2012) Sean M. Green et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Genistein Suppresses Prostate Cancer Growth through Inhibition of Oncogenic MicroRNA-151
- (2012) Takeshi Chiyomaru et al. PLoS One
- Resveratrol Reduces Prostate Cancer Growth and Metastasis by Inhibiting the Akt/MicroRNA-21 Pathway
- (2012) Sandeep Sheth et al. PLoS One
- Quercetin Inhibits Angiogenesis Mediated Human Prostate Tumor Growth by Targeting VEGFR- 2 Regulated AKT/mTOR/P70S6K Signaling Pathways
- (2012) Poyil Pratheeshkumar et al. PLoS One
- Lipids and prostate cancer
- (2012) Janel Suburu et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- New therapy targeting differential androgen receptor signaling in prostate cancer stem/progenitor vs. non-stem/progenitor cells
- (2012) Soo Ok Lee et al. Journal of Molecular Cell Biology
- Autophagy inhibition enhances ursolic acid-induced apoptosis in PC3 cells
- (2011) Seoung Woo Shin et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- A metabolic perturbation by U0126 identifies a role for glutamine in resveratrol-induced cell death
- (2011) Michael R. Freeman et al. CANCER BIOLOGY & THERAPY
- Role of E-cadherin in Antimigratory and Antiinvasive Efficacy of Silibinin in Prostate Cancer Cells
- (2011) G. Deep et al. Cancer Prevention Research
- Randomized, Double-Blind, Placebo-Controlled Trial of Polyphenon E in Prostate Cancer Patients before Prostatectomy: Evaluation of Potential Chemopreventive Activities
- (2011) M. M. Nguyen et al. Cancer Prevention Research
- Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors
- (2011) C. Cai et al. CANCER RESEARCH
- Quercetin inhibits invasion, migration and signalling molecules involved in cell survival and proliferation of prostate cancer cell line (PC-3)
- (2011) Kalimuthu Senthilkumar et al. CELL BIOCHEMISTRY AND FUNCTION
- TGF-β Receptor Signaling Pathways in Angiogenesis; Emerging Targets for Anti-Angiogenesis Therapy
- (2011) Laurens A. van Meeteren et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice
- (2011) Muthu K. Shanmugam et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Red ginseng and 20(S)-Rg3 control testosterone-induced prostate hyperplasia by deregulating androgen receptor signaling
- (2011) Jung-Soo Bae et al. Journal of Natural Medicines
- Berberine Suppresses Androgen Receptor Signaling in Prostate Cancer
- (2011) J. Li et al. MOLECULAR CANCER THERAPEUTICS
- Unknown
- (2011) Mark Ledesma et al. MOLECULAR MEDICINE
- Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells
- (2011) John D. Clarke et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Inhibition of IGF-1 Signaling by Genistein: Modulation of E-Cadherin Expression and Downregulation of β-Catenin Signaling in Hormone Refractory PC-3 Prostate Cancer Cells
- (2011) Joomin Lee et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Down-regulation of phosphoglucomutase 3 mediates sulforaphane-induced cell death in LNCaP prostate cancer cells
- (2011) Chan-Hee Lee et al. Proteome Science
- Lipid raft cholesterol and genistein inhibit the cell viability of prostate cancer cells via the partial contribution of EGFR-Akt/p70S6k pathway and down-regulation of androgen receptor
- (2010) Hea Young Oh et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- MicroRNAs 221/222 and Genistein-Mediated Regulation of ARHI Tumor Suppressor Gene in Prostate Cancer
- (2010) Y. Chen et al. Cancer Prevention Research
- Common Botanical Compounds Inhibit the Hedgehog Signaling Pathway in Prostate Cancer
- (2010) A. Slusarz et al. CANCER RESEARCH
- De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation
- (2010) E. Rysman et al. CANCER RESEARCH
- Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway
- (2010) X. Pang et al. CANCER RESEARCH
- Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells
- (2010) Y. Suh et al. CARCINOGENESIS
- Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting
- (2010) Chrisostomi Gialeli et al. FEBS Journal
- Gamma-tocotrienol as an effective agent in targeting prostate cancer stem cell-like population
- (2010) Sze Ue Luk et al. INTERNATIONAL JOURNAL OF CANCER
- Ursolic acid overcomes Bcl-2-mediated resistance to apoptosis in prostate cancer cells involving activation of JNK-induced Bcl-2 phosphorylation and degradation
- (2010) Yu-xi Zhang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Metabolic alterations and targeted therapies in prostate cancer
- (2010) Richard Flavin et al. JOURNAL OF PATHOLOGY
- Autophagy: cellular and molecular mechanisms
- (2010) Danielle Glick et al. JOURNAL OF PATHOLOGY
- Luteolin and gefitinib regulation of EGF signaling pathway and cell cycle pathway genes in PC-3 human prostate cancer cells
- (2010) Barry M. Markaverich et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Quercetin regulates insulin like growth factor signaling and induces intrinsic and extrinsic pathway mediated apoptosis in androgen independent prostate cancer cells (PC-3)
- (2010) Kalimuthu Senthilkumar et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Suppression of the androgen receptor function by quercetin through protein–protein interactions of Sp1, c-Jun, and the androgen receptor in human prostate cancer cells
- (2010) Huiqing Yuan et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Ursolic acid induces PC-3 cell apoptosis via activation of JNK and inhibition of Akt pathways in vitro
- (2010) Yuxi Zhang et al. MOLECULAR CARCINOGENESIS
- A Nutrient Approach to Prostate Cancer Prevention: The Selenium and Vitamin E Cancer Prevention Trial (SELECT)
- (2010) Barbara K. Dunn et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases
- (2010) Y Liu et al. ONCOGENE
- Natural Proteasome Inhibitor Celastrol Suppresses Androgen-Independent Prostate Cancer Progression by Modulating Apoptotic Proteins and NF-kappaB
- (2010) Yao Dai et al. PLoS One
- A study of high-dose oral silybin-phytosome followed by prostatectomy in patients with localized prostate cancer
- (2010) Thomas W. Flaig et al. PROSTATE
- Silibinin inhibits prostate cancer invasion, motility and migration by suppressing vimentin and MMP-2 expression
- (2009) Kai-jie Wu et al. ACTA PHARMACOLOGICA SINICA
- Phosphorylation of Bcl-2 and activation of caspase-3 via the c-Jun N-terminal kinase pathway in ursolic acid-induced DU145 cells apoptosis
- (2009) Yu-xi Zhang et al. BIOCHIMIE
- The Chemopreventive Bioflavonoid Apigenin Inhibits Prostate Cancer Cell Motility through the Focal Adhesion Kinase/Src Signaling Mechanism
- (2009) C. A. Franzen et al. Cancer Prevention Research
- Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen, Hepatocyte Growth Factor, and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro
- (2009) J. McLarty et al. Cancer Prevention Research
- Silibinin Feeding Alters the Metabolic Profile in TRAMP Prostatic Tumors: 1H-NMRS-Based Metabolomics Study
- (2009) K. Raina et al. CANCER RESEARCH
- A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion-Resistant Growth
- (2009) Z. Guo et al. CANCER RESEARCH
- Resveratrol enhances p53 acetylation and apoptosis in prostate cancer by inhibiting MTA1/NuRD complex
- (2009) Li Kai et al. INTERNATIONAL JOURNAL OF CANCER
- MEK4 Function, Genistein Treatment, and Invasion of Human Prostate Cancer Cells
- (2009) Li Xu et al. JNCI-Journal of the National Cancer Institute
- Antimetastatic potential of fisetin involves inactivation of the PI3K/Akt and JNK signaling pathways with downregulation of MMP-2/9 expressions in prostate cancer PC-3 cells
- (2009) Chi-Sheng Chien et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- D,L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells
- (2009) S.-H. Kim et al. MOLECULAR CANCER THERAPEUTICS
- Inhibition of fatty acid synthase by luteolin post-transcriptionally down-regulates c-Met expression independent of proteosomal/lysosomal degradation
- (2009) D. T. Coleman et al. MOLECULAR CANCER THERAPEUTICS
- Cellular Responses to Cancer Chemopreventive Agent D,L-Sulforaphane in Human Prostate Cancer Cells Are Initiated by Mitochondrial Reactive Oxygen Species
- (2009) Dong Xiao et al. PHARMACEUTICAL RESEARCH
- Pharmacokinetics and Pharmacodynamics of Broccoli Sprouts on the Suppression of Prostate Cancer in Transgenic Adenocarcinoma of Mouse Prostate (TRAMP) Mice: Implication of Induction of Nrf2, HO-1 and Apoptosis and the Suppression of Akt-dependent Kinase Pathway
- (2009) Young-Sam Keum et al. PHARMACEUTICAL RESEARCH
- Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6
- (2009) A. Gibbs et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alterations in cholesterol regulation contribute to the production of intratumoral androgens during progression to castration-resistant prostate cancer in a mouse xenograft model
- (2009) Carlos G. Leon et al. PROSTATE
- Regulation of cell survival by resveratrol involves inhibition of NFκB-regulated gene expression in prostate cancer cells
- (2009) Dixan A. Benitez et al. PROSTATE
- A novel anti-cancer effect of genistein: reversal of epithelial mesenchymal transition in prostate cancer cells1
- (2008) Lin-lin ZHANG et al. ACTA PHARMACOLOGICA SINICA
- Role of Bax in quercetin-induced apoptosis in human prostate cancer cells
- (2008) Dae-Hee Lee et al. BIOCHEMICAL PHARMACOLOGY
- γ-Tocotrienol suppresses prostate cancer cell proliferation and invasion through multiple-signalling pathways
- (2008) W N Yap et al. BRITISH JOURNAL OF CANCER
- Suppression of androgen receptor signaling and prostate specific antigen expression by (−)-epigallocatechin-3-gallate in different progression stages of LNCaP prostate cancer cells
- (2008) Chih-Pin Chuu et al. CANCER LETTERS
- A Novel Dietary Flavonoid Fisetin Inhibits Androgen Receptor Signaling and Tumor Growth in Athymic Nude Mice
- (2008) N. Khan et al. CANCER RESEARCH
- Stage-Specific Inhibitory Effects and Associated Mechanisms of Silibinin on Tumor Progression and Metastasis in Transgenic Adenocarcinoma of the Mouse Prostate Model
- (2008) K. Raina et al. CANCER RESEARCH
- Differential effects of resveratrol on androgen-responsive LNCaP human prostate cancer cells in vitro and in vivo
- (2008) T. T.Y. Wang et al. CARCINOGENESIS
- Honokiol, a Constituent of Oriental Medicinal Herb Magnolia officinalis, Inhibits Growth of PC-3 Xenografts In vivo in Association with Apoptosis Induction
- (2008) E.-R. Hahm et al. CLINICAL CANCER RESEARCH
- Silibinin Inhibits Established Prostate Tumor Growth, Progression, Invasion, and Metastasis and Suppresses Tumor Angiogenesis and Epithelial-Mesenchymal Transition in Transgenic Adenocarcinoma of the Mouse Prostate Model Mice
- (2008) R. P. Singh et al. CLINICAL CANCER RESEARCH
- Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers
- (2008) Scott M. Lippman et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Regulation of Akt/FOXO3a/GSK-3β/AR Signaling Network by Isoflavone in Prostate Cancer Cells
- (2008) Yiwei Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Quercetin suppresses hypoxia-induced accumulation of hypoxia-inducible factor-1α (HIF-1α) through inhibiting protein synthesis
- (2008) Dae-Hee Lee et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Plasma Isoflavones and Subsequent Risk of Prostate Cancer in a Nested Case-Control Study: The Japan Public Health Center
- (2008) Norie Kurahashi et al. JOURNAL OF CLINICAL ONCOLOGY
- Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
- (2008) Shashwati Basak et al. MOLECULAR CANCER THERAPEUTICS
- Curcumin inhibits Akt/mammalian target of rapamycin signaling through protein phosphatase-dependent mechanism
- (2008) S. Yu et al. MOLECULAR CANCER THERAPEUTICS
- Inhibition of HIF-1 alpha and VEGF expression by the chemopreventive bioflavonoid apigenin is accompanied by Akt inhibition in human prostate carcinoma PC3-M cells
- (2008) Salida Mirzoeva et al. MOLECULAR CARCINOGENESIS
- Treatment of PC-3 and DU145 prostate cancer cells by prenylflavonoids from hop (Humulus lupulus L.) induces a caspase-independent form of cell death
- (2007) L. Delmulle et al. PHYTOTHERAPY RESEARCH
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