Inhibiting inducible miR-223 further reduces viable cells in human cancer cell lines MCF-7 and PC3 treated by celastrol

MicroRNA-223 regulates inflammation and brain injury via feedback to NLRP3 inflammasome after intracerebral hemorrhage

(2015) Zhao Yang et al.   MOLECULAR IMMUNOLOGY

Increased microRNA-223 inHelicobacter pylori-associated gastric cancer contributed to cancer cell proliferation and migration

(2014) Lianjun Ma et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Peptide deformylase inhibitor actinonin reduces celastrol’s HSP70 induction while synergizing proliferation inhibition in tumor cells

(2014) Bin Peng et al.   BMC CANCER

Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia

(2014) V Kumar et al.   LEUKEMIA

Celastrol Induces Apoptosis of Gastric Cancer Cells by miR-21 Inhibiting PI3K/Akt-NF-κB Signaling Pathway

(2014) Min Sha et al.   PHARMACOLOGY

miR-223 Is a Coordinator of Breast Cancer Progression as Revealed by Bioinformatics Predictions

(2014) Eva Maria Pinatel et al.   PLoS One

Celastrol Blocks Interleukin-6 Gene Expression via Downregulation of NF-κB in Prostate Carcinoma Cells

(2014) Kun-Chun Chiang et al.   PLoS One

MicroRNA-223 coordinates cholesterol homeostasis

(2014) Kasey C. Vickers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Celastrol targets proteostasis and acts synergistically with a heat-shock protein 90 inhibitor to kill human glioblastoma cells

(2014) S Boridy et al.   Cell Death & Disease

MiR-223-3p targeting SEPT6 promotes the biological behavior of prostate cancer

(2014) Yongbao Wei et al.   Scientific Reports

Cancerous inhibitor of PP2A is targeted by natural compound celastrol for degradation in non-small-cell lung cancer

(2013) Zi Liu et al.   CARCINOGENESIS

miR-224 is Critical for Celastrol-Induced Inhibition of Migration and Invasion of Hepatocellular Carcinoma Cells

(2013) Hangyu Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Hsp70 silencing with siRNA in nanocarriers enhances cancer cell death induced by the inhibitor of Hsp90

(2013) Mirela Matokanovic et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

MicroRNA-223 controls susceptibility to tuberculosis by regulating lung neutrophil recruitment

(2013) Anca Dorhoi et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-223: infection, inflammation and cancer

(2013) M. Haneklaus et al.   JOURNAL OF INTERNAL MEDICINE

MiR-223 downregulation promotes glomerular endothelial cell activation by upregulating importin α4 and α5 in IgA nephropathy

(2013) Hao Bao et al.   KIDNEY INTERNATIONAL

Celastrol inhibits growth and induces apoptotic cell death in melanoma cells via the activation ROS-dependent mitochondrial pathway and the suppression of PI3K/AKT signaling

(2012) Ju-Hye Lee et al.   APOPTOSIS

Celastrol Suppresses Growth and Induces Apoptosis of Human Hepatocellular Carcinoma through the Modulation of STAT3/JAK2 Signaling Cascade In Vitro and In Vivo

(2012) P. Rajendran et al.   Cancer Prevention Research

Heat Shock Protein 90B1 Plays an Oncogenic Role and is a Target of microRNA-223 in Human Osteosarcoma

(2012) Guodong Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Celastrol suppresses breast cancer MCF-7 cell viability via the AMP-activated protein kinase (AMPK)-induced p53–polo like kinase 2 (PLK-2) pathway

(2012) Ji Hae Kim et al.   CELLULAR SIGNALLING

ChIPBase: a database for decoding the transcriptional regulation of long non-coding RNA and microRNA genes from ChIP-Seq data

(2012) Jian-Hua Yang et al.   NUCLEIC ACIDS RESEARCH

Celastrol Inhibits Breast Cancer Cell Invasion via Suppression of NF-ĸB-mediated Matrix Metalloproteinase-9 Expression

(2011) Yoonseo Kim et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells

(2011) Mei Yang et al.   Molecular Cancer

MiR-223 Suppresses Cell Proliferation by Targeting IGF-1R

(2011) Cheng You Jia et al.   PLoS One

Molecular targets of celastrol derived from Thunder of God Vine: Potential role in the treatment of inflammatory disorders and cancer

(2010) Radhamani Kannaiyan et al.   CANCER LETTERS

Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway

(2010) X. Pang et al.   CANCER RESEARCH

MicroRNA-223 regulates Glut4 expression and cardiomyocyte glucose metabolism

(2010) Han Lu et al.   CARDIOVASCULAR RESEARCH

HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way

(2010) Bin Peng et al.   Molecular Cancer

A routinely applicable way for using FCM in cell enumeration with CFSE-labeled CellBeads as internal standard

(2009) Fan-Fan Cao et al.   CYTOMETRY PART A