PBX3 in Cancer

EWSR1 -PBX3 fused myoepithelioma arising in metatarsal bone: Case report and review of the literature

(2019) Sumi Yun et al.   PATHOLOGY INTERNATIONAL

miR-302a inhibits human HepG2 and SMMC-7721 cells proliferation and promotes apoptosis by targeting MAP3K2 and PBX3

(2019) Meng Wang et al.   Scientific Reports

By downregulating PBX3, miR-526b suppresses the epithelial–mesenchymal transition process in cervical cancer cells

(2019) Hongfang Li et al.   Future Oncology

Cutaneous Syncytial Myoepithelioma is Characterized by Recurrent EWSR1-PBX3 Fusions

(2019) Vickie Y. Jo et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

PBX3 hypermethylation in peripheral blood leukocytes predicts better prognosis in colorectal cancer: A propensity score analysis

(2019) Hongru Sun et al.   Cancer Medicine

microRNAs in Cardiovascular Disease: Small Molecules but Big Roles

(2019) Bingqian Yan et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

MicroRNAs in cancer cell death pathways: Apoptosis and necroptosis

(2019) Solmaz Shirjang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Recent drug approvals for acute myeloid leukemia

(2019) Catherine Lai et al.   Journal of Hematology & Oncology

LncRNA ANRIL promotes cell growth, migration and invasion of hepatocellular carcinoma cells via sponging miR-144

(2019) Yongbiao Ma et al.   ANTI-CANCER DRUGS

Elevated HOX gene expression in acute myeloid leukemia is associated with NPM1 mutations and poor survival

(2019) Ádám Nagy et al.   Journal of Advanced Research

MicroRNA-320a suppresses tumor progression by targeting PBX3 in gastric cancer and is downregulated by DNA methylation

(2019) Yong-Shuang Li et al.   World Journal of Gastrointestinal Oncology

PBX3 Is Part of an EMT Regulatory Network and Indicates Poor Outcome in Colorectal Cancer

(2018) Sebastian Lamprecht et al.   CLINICAL CANCER RESEARCH

PBX3/MEK/ERK1/2/LIN28/let-7b positive feedback loop enhances mesenchymal phenotype to promote glioblastoma migration and invasion

(2018) Xiupeng Xu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Nuclear functions of mammalian MicroRNAs in gene regulation, immunity and cancer

(2018) Hongyu Liu et al.   Molecular Cancer

miR-495 inhibits proliferation, migration, and invasion and induces apoptosis via inhibiting PBX3 in melanoma cells

(2018) Guangxiong Chen et al.   OncoTargets and Therapy

Trib2 expression in granulocyte-monocyte progenitors drives a highly drug resistant acute myeloid leukaemia linked to elevated Bcl2

(2018) Caitriona O'Connor et al.   Oncotarget

Inactivation of PBX3 and HOXA9 by down-regulating H3K79 methylation represses NPM1-mutated leukemic cell survival

(2018) Wu Zhang et al.   Theranostics

Functional testing of a human PBX3 variant in zebrafish reveals a potential modifier role in congenital heart defects

(2018) Gist H. Farr et al.   Disease Models & Mechanisms

Isolation, identification, and characterization of cancer stem cells: A review

(2017) Mohammad Reza Abbaszadegan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Silencing Pre-B-cell leukemia homeobox 3 decreases the proliferation of human glioma cells in vitro and in vivo

(2017) Xiupeng Xu et al.   JOURNAL OF NEURO-ONCOLOGY

Safety and activity of microRNA-loaded minicells in patients with recurrent malignant pleural mesothelioma: a first-in-man, phase 1, open-label, dose-escalation study

(2017) Nico van Zandwijk et al.   LANCET ONCOLOGY

Long Noncoding RNA Urothelial Carcinoma Associated 1 Promotes the Proliferation and Metastasis of Human Lung Tumor Cells by Regulating MicroRNA-144

(2017) Dagang Li et al.   ONCOLOGY RESEARCH

PBX3 is associated with proliferation and poor prognosis in patients with cervical cancer

(2017) Hongfang Li et al.   OncoTargets and Therapy

High level of homeobox A9 and PBX homeobox 3 expression in gastric cancer correlates with poor prognosis

(2017) Ying‑Yu Ma et al.   Oncology Letters

TRIB2 confers resistance to anti-cancer therapy by activating the serine/threonine protein kinase AKT

(2017) Richard Hill et al.   Nature Communications

Targeting HOX/PBX dimers in cancer

(2017) Richard Morgan et al.   Oncotarget

miR-320a regulates cell proliferation and apoptosis in multiple myeloma by targeting pre-B-cell leukemia transcription factor 3

(2016) Yinghao Lu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the MLL-Rearranged Disease

(2016) Z. Li et al.   CANCER RESEARCH

PBX3 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition

(2016) Shuanhu Wang et al.   Oncology Letters

MicroRNA-33a-3p suppresses cell migration and invasion by directly targeting PBX3 in human hepatocellular carcinoma

(2016) Shu-Yan Han et al.   Oncotarget

The role of Myc and let-7a in glioblastoma, glucose metabolism and response to therapy

(2015) Gang Wang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Pbx3 and Meis1 cooperate through multiple mechanisms to support Hox-induced murine leukemia

(2015) M.-P. Garcia-Cuellar et al.   HAEMATOLOGICA

PBX3 is targeted by multiple miRNAs and is essential for liver tumour-initiating cells

(2015) Haibo Han et al.   Nature Communications

Pbx3 and Meis1 cooperate through multiple mechanisms to support Hox-induced murine leukemia

(2015) M.-P. Garcia-Cuellar et al.   HAEMATOLOGICA

Fusion of the Genes EWSR1 and PBX3 in Retroperitoneal Leiomyoma with t(9;22)(q33;q12)

(2015) Ioannis Panagopoulos et al.   PLoS One

PBX3 promotes migration and invasion of colorectal cancer cellsviaactivation of MAPK/ERK signaling pathway

(2015) Hai-Bo Han   WORLD JOURNAL OF GASTROENTEROLOGY

CBFB-MYH11 hypomethylation signature and PBX3 differential methylation revealed by targeted bisulfite sequencing in patients with acute myeloid leukemia

(2014) Hana Hájková et al.   Journal of Hematology & Oncology

The miR-302 cluster transcriptionally regulated by POUV, SOX and STAT5B controls the undifferentiated state through the post-transcriptional repression of PBX3 and E2F7 in early chick development

(2014) Sang In Lee et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates

(2013) E. Longobardi et al.   DEVELOPMENTAL DYNAMICS

HOXA/PBX3 knockdown impairs growth and sensitizes cytogenetically normal acute myeloid leukemia cells to chemotherapy

(2013) G. J. Dickson et al.   HAEMATOLOGICA

PBX3 is overexpressed in gastric cancer and regulates cell proliferation

(2013) Yanke Li et al.   TUMOR BIOLOGY

Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML

(2012) Z. Li et al.   BLOOD

PBX3 is an important cofactor of HOXA9 in leukemogenesis

(2012) Z. Li et al.   BLOOD

Gene expression profiling and candidate gene resequencing identifies pathways and mutations important for malignant transformation caused by leukemogenic fusion genes

(2012) Rachel L. Novak et al.   EXPERIMENTAL HEMATOLOGY

miR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia

(2012) X. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Let-7c functions as a metastasis suppressor by targeting MMP11 and PBX3 in colorectal cancer

(2011) Hai-Bo Han et al.   JOURNAL OF PATHOLOGY

Regulation of PBX3 expression by androgen and Let-7d in prostate cancer

(2011) Håkon Ramberg et al.   Molecular Cancer

Hox genes and regional patterning of the vertebrate body plan

(2010) Moises Mallo et al.   DEVELOPMENTAL BIOLOGY

Human TRIB2 is a repressor of FOXO that contributes to the malignant phenotype of melanoma cells

(2010) F Zanella et al.   ONCOGENE