The Emerging Roles of Endoplasmic Reticulum Stress in Balancing Immunity and Tolerance in Health and Diseases: Mechanisms and Opportunities

Treatment of established TH2 cells with 4μ8c, an inhibitor of IRE1α, blocks IL-5 but not IL-4 secretion

(2019) Cody Poe et al.   BMC IMMUNOLOGY

Specific PERK inhibitors enhanced glucose-stimulated insulin secretion in a mouse model of type 2 diabetes

(2019) Min Joo Kim et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Endoplasmic Reticulum Stress Contributes to Mitochondrial Exhaustion of CD8 T cells

(2019) Katie Hurst et al.   Cancer Immunology Research

IRE1α Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8+ T Cell Priming

(2019) Bernardita Medel et al.   Frontiers in Immunology

ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression

(2019) Yu Cao et al.   Nature Communications

Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR

(2019) Denis A. Mogilenko et al.   CELL

Cholesterol Induces CD8+ T Cell Exhaustion in the Tumor Microenvironment

(2019) Xingzhe Ma et al.   Cell Metabolism

Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness

(2019) Jingxia Wu et al.   IMMUNITY

The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc

(2019) Han Dong et al.   NATURE IMMUNOLOGY

TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection

(2019) Francesca Alfei et al.   NATURE

TOX is a critical regulator of tumour-specific T cell differentiation

(2019) Andrew C. Scott et al.   NATURE

TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

(2019) Omar Khan et al.   NATURE

Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection

(2019) Chen Yao et al.   NATURE IMMUNOLOGY

TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion

(2019) Hyungseok Seo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation

(2019) Samuel Lara-Reyna et al.   Frontiers in Immunology

Endoplasmic Reticulum Stress signalling - from basic mechanisms to clinical applications

(2018) Aitor Almanza et al.   FEBS Journal

IRE1α Aggravates Ischemia Reperfusion Injury of Fatty Liver by Regulating Phenotypic Transformation of Kupffer Cells

(2018) Faji Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization

(2018) Chih-Hang Anthony Tang et al.   JOURNAL OF CELL BIOLOGY

Inhibition of endoplasmic-reticulum-stress-mediated autophagy enhances the effectiveness of chemotherapeutics on pancreatic cancer

(2018) Prakash C. Thakur et al.   Journal of Translational Medicine

ATF4 Regulates CD4 + T Cell Immune Responses through Metabolic Reprogramming

(2018) Xi Yang et al.   Cell Reports

Critical review: involvement of endoplasmic reticulum stress in the aetiology of Alzheimer's disease

(2018) Shoko Hashimoto et al.   Open Biology

IRE1α Implications in Endoplasmic Reticulum Stress-Mediated Development and Pathogenesis of Autoimmune Diseases

(2018) Raghu Patil Junjappa et al.   Frontiers in Immunology

Endoplasmic Reticulum Stress in Metabolic Disorders

(2018) Rose Ghemrawi et al.   Cells

Endoplasmic reticulum stress induces inverse regulations of major functions in portal myofibroblasts during liver fibrosis progression

(2018) Emilien Loeuillard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

ER-stress regulates macrophage polarization through pancreatic EIF-2alpha kinase

(2018) Faji Yang et al.   CELLULAR IMMUNOLOGY

Activated ATF6 Induces Intestinal Dysbiosis and Innate Immune Response to Promote Colorectal Tumorigenesis

(2018) Olivia I. Coleman et al.   GASTROENTEROLOGY

IL-6 mediates ER expansion during hyperpolarization of alternatively activated macrophages

(2018) Ehab A Ayaub et al.   IMMUNOLOGY AND CELL BIOLOGY

IRE1α–XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity

(2018) Minkyung Song et al.   NATURE

Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation

(2018) Jhuma Pramanik et al.   Genome Medicine

Inositol-Requiring Enzyme 1 Alpha Endoribonuclease Specific Inhibitor STF-083010 Alleviates Carbon Tetrachloride Induced Liver Injury and Liver Fibrosis in Mice

(2018) Qian-Qian Chen et al.   Frontiers in Pharmacology

Inhibition of Human Dendritic Cell ER Stress Response Reduces T Cell Alloreactivity Yet Spares Donor Anti-tumor Immunity

(2018) Brian C. Betts et al.   Frontiers in Immunology

Role of Endoplasmic Reticulum Stress in Proinflammatory Cytokine–Mediated Inhibition of Trophoblast Invasion in Placenta-Related Complications of Pregnancy

(2018) Cheuk-Lun Lee et al.   AMERICAN JOURNAL OF PATHOLOGY

Attenuation of PERK enhances glucose-stimulated insulin secretion in islets

(2017) Min Joo Kim et al.   JOURNAL OF ENDOCRINOLOGY

The Trojan horse - neuroinflammatory impact of T cells in neurodegenerative diseases

(2017) Annika Sommer et al.   Molecular Neurodegeneration

Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival

(2017) Simon J. Tavernier et al.   NATURE CELL BIOLOGY

CNPY2 is a key initiator of the PERK–CHOP pathway of the unfolded protein response

(2017) Feng Hong et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Knockdown of IRE1α inhibits colonic tumorigenesis through decreasing β-catenin and IRE1α targeting suppresses colon cancer cells

(2017) X-X Li et al.   ONCOGENE

Targeting IRE1 with small molecules counteracts progression of atherosclerosis

(2017) Ozlem Tufanli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Melatonin, a novel selective ATF-6 inhibitor, induces human hepatoma cell apoptosis through COX-2 downregulation

(2017) Li-Jia Bu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

CNPY2 is a key initiator of the PERK–CHOP pathway of the unfolded protein response

(2017) Feng Hong et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Unfolded protein response signaling impacts macrophage polarity to modulate breast cancer cell clearance and melanoma immune checkpoint therapy responsiveness

(2017) David R. Soto-Pantoja et al.   Oncotarget

Cellular Stress in the Context of an Inflammatory Environment Supports TGF-β-Independent T Helper-17 Differentiation

(2017) Verena Brucklacher-Waldert et al.   Cell Reports

Modulation of Endoplasmic Reticulum Stress Controls CD4 + T-cell Activation and Antitumor Function

(2017) Jessica E. Thaxton et al.   Cancer Immunology Research

Intestinal Epithelial Cell Endoplasmic Reticulum Stress and Inflammatory Bowel Disease Pathogenesis: An Update Review

(2017) Xiaoshi Ma et al.   Frontiers in Immunology

Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94

(2016) Ephraim A. Ansa-Addo et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Proplatelet formation in megakaryocytes is associated with endoplasmic reticulum stress

(2016) Nobuhiro Morishima et al.   GENES TO CELLS

The Unfolded Protein Response in Homeostasis and Modulation of Mammalian Immune Cells

(2016) Ana Sofia Martins et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Leptin Enhances TH2 and ILC2 Responses in Allergic Airway Disease

(2016) Handong Zheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response

(2016) Julie Tellier et al.   NATURE IMMUNOLOGY

XBP1: A Pivotal Transcriptional Regulator of Glucose and Lipid Metabolism

(2016) Christina Piperi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia

(2016) Haibo Sun et al.   Oncotarget

ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis

(2015) Juan R. Cubillos-Ruiz et al.   CELL

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

(2015) Chih-Hao Chang et al.   CELL

Lipid-dependent regulation of the unfolded protein response

(2015) Romain Volmer et al.   CURRENT OPINION IN CELL BIOLOGY

Atrazine induces endoplasmic reticulum stress-mediated apoptosis of T lymphocytes via the caspase-8-dependent pathway

(2015) Eun-Jin Lee et al.   ENVIRONMENTAL TOXICOLOGY

T cell metabolism drives immunity

(2015) Michael D. Buck et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia

(2015) Susanne Kohl et al.   NATURE GENETICS

Targeting the IRE1α–XBP1 branch of the unfolded protein response in human diseases

(2015) Dadi Jiang et al.   SEMINARS IN CANCER BIOLOGY

Endoplasmic Reticulum Stress in Intestinal Epithelial Cell Function and Inflammatory Bowel Disease

(2015) Katherine Luo et al.   Gastroenterology Research and Practice

The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly

(2015) Carmela Sidrauski et al.   eLife

Endoplasmic Reticulum Stress, Genome Damage, and Cancer

(2015) Naomi Dicks et al.   Frontiers in Oncology

Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells

(2015) Bo-Ra Lee et al.   Oncotarget

ATF6 Mediates a Pro-Inflammatory Synergy Between ER Stress and TLR Activation in the Pathogenesis of Liver Ischemia-Reperfusion Injury

(2014) J. Rao et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Allosteric Inhibition of the IRE1α RNase Preserves Cell Viability and Function during Endoplasmic Reticulum Stress

(2014) Rajarshi Ghosh et al.   CELL

The Stress-Response Sensor Chop Regulates the Function and Accumulation of Myeloid-Derived Suppressor Cells in Tumors

(2014) Paul T. Thevenot et al.   IMMUNITY

Inhibition of ER stress–associated IRE-1/XBP-1 pathway reduces leukemic cell survival

(2014) Chih-Hang Anthony Tang et al.   JOURNAL OF CLINICAL INVESTIGATION

ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R–mediated apoptosis

(2014) Thomas Condamine et al.   JOURNAL OF CLINICAL INVESTIGATION

Endoplasmic Reticulum Stress Regulator XBP-1 Contributes to Effector CD8+ T Cell Differentiation during Acute Infection

(2014) D. Kamimura et al.   JOURNAL OF IMMUNOLOGY

KDEL-Retained Antigen in B Lymphocytes Induces a Proinflammatory Response: A Possible Role for Endoplasmic Reticulum Stress in Adaptive T Cell Immunity

(2014) M. C. Wheeler et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Endoplasmic Reticulum Stress Licenses Macrophages To Produce Mature IL-1  in Response to TLR4 Stimulation through a Caspase-8- and TRIF-Dependent Pathway

(2014) K. Shenderov et al.   JOURNAL OF IMMUNOLOGY

A pathogenic role for ER stress-induced autophagy and ER chaperone GRP78/BiP in T lymphocyte systemic lupus erythematosus

(2014) Won-Seok Lee et al.   JOURNAL OF LEUKOCYTE BIOLOGY

T-cell-mediated regulation of neuroinflammation involved in neurodegenerative diseases

(2014) Hugo González et al.   Journal of Neuroinflammation

Elevated Endoplasmic Reticulum Stress Response Contributes to Adipose Tissue Inflammation in Aging

(2014) Amiya Kumar Ghosh et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

PERK-Dependent Activation of JAK1 and STAT3 Contributes to Endoplasmic Reticulum Stress-Induced Inflammation

(2014) G. P. Meares et al.   MOLECULAR AND CELLULAR BIOLOGY

X Box-Binding Protein 1 Regulates Angiogenesis in Human Pancreatic Adenocarcinomas

(2014) Lorenzo Romero-Ramirez et al.   Translational Oncology

Physiological roles of regulated Ire1 dependent decay

(2014) Dina S. Coelho et al.   Frontiers in Genetics

Emodin induces human T cell apoptosis in vitro by ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction

(2013) Kai Qu et al.   ACTA PHARMACOLOGICA SINICA

Ca2+-dependent endoplasmic reticulum stress correlates with astrogliosis in oligomeric amyloid β-treated astrocytes and in a model of Alzheimer's disease

(2013) Elena Alberdi et al.   AGING CELL

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Acidic extracellular microenvironment and cancer

(2013) Yasumasa Kato et al.   Cancer Cell International

Characterization of a Novel PERK Kinase Inhibitor with Antitumor and Antiangiogenic Activity

(2013) C. Atkins et al.   CANCER RESEARCH

The Serine-threonine Kinase Inositol-requiring Enzyme 1α (IRE1α) Promotes IL-4 Production in T Helper Cells

(2013) Kyeorda L. Kemp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting the unfolded protein response in disease

(2013) Claudio Hetz et al.   NATURE REVIEWS DRUG DISCOVERY

Negative feedback by IRE1  optimizes mucin production in goblet cells

(2013) A. Tsuru et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IRE1: ER stress sensor and cell fate executor

(2013) Yani Chen et al.   TRENDS IN CELL BIOLOGY

Discovery of GSK2656157: An Optimized PERK Inhibitor Selected for Preclinical Development

(2013) Jeffrey M. Axten et al.   ACS Medicinal Chemistry Letters

Signaling Pathways from the Endoplasmic Reticulum and Their Roles in Disease

(2013) Hisae Kadowaki et al.   Genes

Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences

(2013) Angela M. Arensdorf et al.   Frontiers in Genetics

Endoplasmic Reticulum Stress and Type 2 Diabetes

(2012) Sung Hoon Back et al.   Annual Review of Biochemistry

Pharmacological targeting of endoplasmic reticulum stress signaling in cancer

(2012) Axel H. Schönthal   BIOCHEMICAL PHARMACOLOGY

Blockade of XBP1 splicing by inhibition of IRE1  is a promising therapeutic option in multiple myeloma

(2012) N. Mimura et al.   BLOOD

Endoplasmic Reticulum Stress Response Promotes Cytotoxic Phenotype of CD8  + Intraepithelial Lymphocytes in a Mouse Model for Crohn's Disease-like Ileitis

(2012) J.-S. Chang et al.   JOURNAL OF IMMUNOLOGY

High Rate of Antibody Secretion Is not Integral to Plasma Cell Differentiation as Revealed by XBP-1 Deficiency

(2012) N. Taubenheim et al.   JOURNAL OF IMMUNOLOGY

Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)

(2012) Jeffrey M. Axten et al.   JOURNAL OF MEDICINAL CHEMISTRY

Regulation of microRNA expression in the heart by the ATF6 branch of the ER stress response

(2012) Peter J. Belmont et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Immune Heterogeneity in Neuroinflammation: Dendritic Cells in the Brain

(2012) Carol A. Colton   Journal of Neuroimmune Pharmacology

Atf6α-null mice are glucose intolerant due to pancreatic β-cell failure on a high-fat diet but partially resistant to diet-induced insulin resistance

(2012) Masahiro Usui et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cell-Extrinsic Effects of Tumor ER Stress Imprint Myeloid Dendritic Cells and Impair CD8+ T Cell Priming

(2012) Navin R. Mahadevan et al.   PLoS One

The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

(2012) B. C. S. Cross et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Folding and Quality Control in the ER

(2012) K. Araki et al.   Cold Spring Harbor Perspectives in Biology

Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing

(2012) M Ri et al.   Blood Cancer Journal

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Constitutive Role for IRE1α-XBP1 Signaling Pathway in the Insulin-Mediated Hepatic Lipogenic Program

(2011) Jie Ning et al.   ENDOCRINOLOGY

ER stress and its regulator X-box-binding protein-1 enhance polyIC-induced innate immune response in dendritic cells

(2011) Fanlei Hu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Dual and opposing roles of the unfolded protein response regulated by IRE1  and XBP1 in proinsulin processing and insulin secretion

(2011) A.-H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endoplasmic reticulum stress, obesity and diabetes

(2011) Miriam Cnop et al.   TRENDS IN MOLECULAR MEDICINE

Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma

(2010) I. Papandreou et al.   BLOOD

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Endoplasmic reticulum stress drives a regulatory phenotype in human T-cell clones

(2010) Alessandra Franco et al.   CELLULAR IMMUNOLOGY

Inflammation in neurodegenerative diseases

(2010) Sandra Amor et al.   IMMUNOLOGY

Induction of Liver Steatosis and Lipid Droplet Formation in ATF6α-Knockout Mice Burdened with Pharmacological Endoplasmic Reticulum Stress

(2010) Keisuke Yamamoto et al.   MOLECULAR BIOLOGY OF THE CELL

TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages

(2010) Fabio Martinon et al.   NATURE IMMUNOLOGY

FFA-Induced Adipocyte Inflammation and Insulin Resistance: Involvement of ER Stress and IKKβ Pathways

(2010) Ping Jiao et al.   Obesity

PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage

(2010) E Bobrovnikova-Marjon et al.   ONCOGENE

Inositol-requiring enzyme 1  is a key regulator of angiogenesis and invasion in malignant glioma

(2010) G. Auf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression

(2010) Jane C. Goodall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates

(2009) Dan Han et al.   CELL

CD4+CD8+ thymocytes are induced to cell death by a small dose of puromycin via ER stress

(2009) Takemi Oguma et al.   CELLULAR IMMUNOLOGY

Developmental plasticity of Th17 and Treg cells

(2009) Yun Kyung Lee et al.   CURRENT OPINION IN IMMUNOLOGY

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

(2009) Julie Hollien et al.   JOURNAL OF CELL BIOLOGY

XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development

(2009) Derrick J. Todd et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CHOP Mediates Endoplasmic Reticulum Stress-Induced Apoptosis in Gimap5-Deficient T Cells

(2009) Steven C. Pino et al.   PLoS One

Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability

(2009) T. Iwawaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

(2008) Arthur Kaser et al.   CELL

ATF6 Is a Transcription Factor Specializing in the Regulation of Quality Control Proteins in the Endoplasmic Reticulum

(2008) Yusuke Adachi et al.   CELL STRUCTURE AND FUNCTION

Endoplasmic reticulum stress and the unfolded protein response are linked to synergistic IFN-β inductionvia X-box binding protein 1

(2008) Judith A. Smith et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

B- and T-cell Development Both Involve Activity of the Unfolded Protein Response Pathway

(2008) Ryan Brunsing et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The tumor microenvironment and its role in promoting tumor growth

(2008) T L Whiteside   ONCOGENE

The Role of IRE1α in the Degradation of Insulin mRNA in Pancreatic β-Cells

(2008) Kathryn L. Lipson et al.   PLoS One

ATF6 -Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo

(2008) D. M. Schewe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activating transcription factor 4

(2007) Kurosh Ameri et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cells

(2007) Jennifer N. Gass et al.   MOLECULAR IMMUNOLOGY