T-cell-mediated regulation of neuroinflammation involved in neurodegenerative diseases

PD1 Negative and PD1 Positive CD4+ T Regulatory Cells in Mild Cognitive Impairment and Alzheimer's Disease

(2017) Marina Saresella et al.   JOURNAL OF ALZHEIMERS DISEASE

Arthritis susceptibility and the gut microbiome

(2014) Veena Taneja   FEBS LETTERS

Oral Tolerance Can Be Established via Gap Junction Transfer of Fed Antigens from CX3CR1+ Macrophages to CD103+ Dendritic Cells

(2014) Elisa Mazzini et al.   IMMUNITY

Essential Role of CD8+CD122+ Regulatory T Cells in the Recovery from Experimental Autoimmune Encephalomyelitis

(2014) Y.-H. Lee et al.   JOURNAL OF IMMUNOLOGY

Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases

(2014) Hugo González et al.   JOURNAL OF NEUROIMMUNOLOGY

Systemic injection of LPS induces region-specific neuroinflammation and mitochondrial dysfunction in normal mouse brain

(2014) Haneul Noh et al.   NEUROCHEMISTRY INTERNATIONAL

Gut microbiota, probiotics and diabetes

(2014) Aline Corado Gomes et al.   Nutrition Journal

GDNF-Transfected Macrophages Produce Potent Neuroprotective Effects in Parkinson's Disease Mouse Model

(2014) Yuling Zhao et al.   PLoS One

Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions

(2014) L. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dopamine receptor 3 might be an essential molecule in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

(2013) Yan Chen et al.   BMC NEUROSCIENCE

Is SOD1 loss of function involved in amyotrophic lateral sclerosis?

(2013) Rachele A. Saccon et al.   BRAIN

CNS-specific T cells shape brain function via the choroid plexus

(2013) Kuti Baruch et al.   BRAIN BEHAVIOR AND IMMUNITY

Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus

(2013) Ravid Shechter et al.   IMMUNITY

Dopamine Receptor D3 Expressed on CD4+ T Cells Favors Neurodegeneration of Dopaminergic Neurons during Parkinson's Disease

(2013) H. Gonzalez et al.   JOURNAL OF IMMUNOLOGY

IFN-  Production by Amyloid  -Specific Th1 Cells Promotes Microglial Activation and Increases Plaque Burden in a Mouse Model of Alzheimer's Disease

(2013) T. C. Browne et al.   JOURNAL OF IMMUNOLOGY

MHCII Is Required for  -Synuclein-Induced Activation of Microglia, CD4 T Cell Proliferation, and Dopaminergic Neurodegeneration

(2013) A. S. Harms et al.   JOURNAL OF NEUROSCIENCE

Plasticity of TH17 cells in Peyer's patches is responsible for the induction of T cell–dependent IgA responses

(2013) Keiji Hirota et al.   NATURE IMMUNOLOGY

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

(2013) Veronique E Miron et al.   NATURE NEUROSCIENCE

Enhanced Chemokine Receptor Expression on Leukocytes of Patients with Alzheimer's Disease

(2013) David Goldeck et al.   PLoS One

Systemic Transplantation of Human Umbilical Cord Derived Mesenchymal Stem Cells-Educated T Regulatory Cells Improved the Impaired Cognition in AβPPswe/PS1dE9 Transgenic Mice

(2013) Hongna Yang et al.   PLoS One

Th17 Cell-Mediated Neuroinflammation Is Involved in Neurodegeneration of Aβ1-42-Induced Alzheimer’s Disease Model Rats

(2013) Jun Zhang et al.   PLoS One

CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging

(2013) K. Baruch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viruses and neurodegeneration

(2013) Li Zhou et al.   Virology Journal

Immunohistochemical study of arginase-1 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis

(2012) Meejung Ahn et al.   BRAIN RESEARCH

Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survival

(2012) Jenny S. Henkel et al.   EMBO Molecular Medicine

Stimulation of Dopamine Receptor D5 Expressed on Dendritic Cells Potentiates Th17-Mediated Immunity

(2012) C. Prado et al.   JOURNAL OF IMMUNOLOGY

Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammation

(2012) Richard Gordon et al.   Journal of Neuroinflammation

CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery

(2012) Moa Fransson et al.   Journal of Neuroinflammation

Induction and molecular signature of pathogenic TH17 cells

(2012) Youjin Lee et al.   NATURE IMMUNOLOGY

Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis

(2011) David R. Beers et al.   BRAIN

Functional Specializations of Intestinal Dendritic Cell and Macrophage Subsets That Control Th17 and Regulatory T Cell Responses Are Dependent on the T Cell/APC Ratio, Source of Mouse Strain, and Regional Localization

(2011) T. L. Denning et al.   JOURNAL OF IMMUNOLOGY

Lymph node-derived donor encephalitogenic CD4+ T cells in C57BL/6 mice adoptive transfer experimental autoimmune encephalomyelitis highly express GM-CSF and T-bet

(2011) Petra D Cravens et al.   Journal of Neuroinflammation

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

(2011) Kerstin Berer et al.   NATURE

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

Physiological Induction of Regulatory Qa-1-Restricted CD8+ T Cells Triggered by Endogenous CD4+ T Cell Responses

(2011) Aditi Varthaman et al.   PLoS One

IFN-γ signaling, with the synergistic contribution of TNF-α, mediates cell specific microglial and astroglial activation in experimental models of Parkinson's disease

(2011) C Barcia et al.   Cell Death & Disease

The role of antigen presenting cells in multiple sclerosis

(2010) Emily M.L. Chastain et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis

(2010) Áine C. Murphy et al.   BRAIN BEHAVIOR AND IMMUNITY

T cells in multiple sclerosis and experimental autoimmune encephalomyelitis

(2010) J. M. Fletcher et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

γδ T Cells Enhance Autoimmunity by Restraining Regulatory T Cell Responses via an Interleukin-23-Dependent Mechanism

(2010) Franziska Petermann et al.   IMMUNITY

What determines Th2 differentiation, in vitro and in vivo ?

(2010) William E Paul   IMMUNOLOGY AND CELL BIOLOGY

Regulation of learning and memory by meningeal immunity: a key role for IL-4

(2010) Noël C. Derecki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulatory T Cells Attenuate Th17 Cell-Mediated Nigrostriatal Dopaminergic Neurodegeneration in a Model of Parkinson’s Disease

(2010) Ashley D. Reynolds et al.   JOURNAL OF IMMUNOLOGY

A role for STAT3 and cathepsin S in IL-10 down-regulation of IFN- -induced MHC class II molecule on primary human blood macrophages

(2010) L. L. Y. Chan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Histamine and histamine receptors in pathogenesis and treatment of multiple sclerosis

(2010) Farhad Jadidi-Niaragh et al.   NEUROPHARMACOLOGY

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Microglia Acquire Distinct Activation Profiles Depending on the Degree of α-Synuclein Neuropathology in a rAAV Based Model of Parkinson's Disease

(2010) Vanesa Sanchez-Guajardo et al.   PLoS One

Novel CD8+Treg suppress EAE by TGF-β- and IFN-γ-dependent mechanisms

(2009) Mei-Ling Chen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Nitrated  -Synuclein-Induced Alterations in Microglial Immunity Are Regulated by CD4+ T Cell Subsets

(2009) A. D. Reynolds et al.   JOURNAL OF IMMUNOLOGY

Immune system alterations in sporadic amyotrophic lateral sclerosis patients suggest an ongoing neuroinflammatory process

(2009) Stefania Mantovani et al.   JOURNAL OF NEUROIMMUNOLOGY

Proteomic Studies of Nitrated Alpha-Synuclein Microglia Regulation by CD4+CD25+ T Cells

(2009) Ashley D. Reynolds et al.   JOURNAL OF PROTEOME RESEARCH

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

(2009) Andrea Reboldi et al.   NATURE IMMUNOLOGY

Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?

(2009) Kurt M. Lucin et al.   NEURON

T cell transfer model of chronic colitis: concepts, considerations, and tricks of the trade

(2008) Dmitry V. Ostanin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Expression of TLR4 and CD14 in the Central Nervous System (CNS) in a MPTP Mouse Model of Parkinson's-Like Disease

(2008) Maria Antonietta Panaro et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Role of Th1 and Th17 cells in organ-specific autoimmunity

(2008) Valérie Dardalhon et al.   JOURNAL OF AUTOIMMUNITY

Nitrated α–Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons

(2008) Eric J. Benner et al.   PLoS One

CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS

(2008) D. R. Beers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS

(2008) I. M. Chiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA