Melatonin, a novel selective ATF-6 inhibitor, induces human hepatoma cell apoptosis through COX-2 downregulation

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Evidence-Based Diagnosis, Staging, and Treatment of Patients With Hepatocellular Carcinoma

(2016) Jordi Bruix et al.   GASTROENTEROLOGY

Melatonin enhances mitochondrial ATP synthesis, reduces reactive oxygen species formation, and mediates translocation of the nuclear erythroid 2-related factor 2 resulting in activation of phase-2 antioxidant enzymes (γ-GCS, HO-1, NQO1) in ultraviolet rad

(2016) Konrad Kleszczyński et al.   JOURNAL OF PINEAL RESEARCH

Endoplasmic reticulum stress eIF2α–ATF4 pathway-mediated cyclooxygenase-2 induction regulates cadmium-induced autophagy in kidney

(2016) B Luo et al.   Cell Death & Disease

Effects of melatonin on HIF-1α and VEGF expression and on the invasive properties of hepatocarcinoma cells

(2016) JUCIMARA COLOMBO et al.   Oncology Letters

Multiple Mechanisms of Unfolded Protein Response–Induced Cell Death

(2015) Nobuhiko Hiramatsu et al.   AMERICAN JOURNAL OF PATHOLOGY

ER Stress and Angiogenesis

(2015) François Binet et al.   Cell Metabolism

Melatonin set out to ER stress signaling thwarts epithelial mesenchymal transition and peritoneal dissemination via calpain-mediated C/EBPβand NFκB cleavage

(2015) Sheng-Mao Wu et al.   JOURNAL OF PINEAL RESEARCH

Melatonin-mediated Bim up-regulation and cyclooxygenase-2 (COX-2) down-regulation enhances tunicamycin-induced apoptosis in MDA-MB-231 cells

(2015) Seon Min Woo et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as a treatment for gastrointestinal cancer: a review

(2015) Zhenlong Xin et al.   JOURNAL OF PINEAL RESEARCH

Melatonin and endoplasmic reticulum stress: relation to autophagy and apoptosis

(2015) Anna Fernández et al.   JOURNAL OF PINEAL RESEARCH

Endoplasmic Reticulum Stress-Activated Cell Reprogramming in Oncogenesis

(2015) E. Chevet et al.   Cancer Discovery

Stress Responses from the Endoplasmic Reticulum in Cancer

(2015) Hironori Kato et al.   Frontiers in Oncology

Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review

(2014) Joaquín J. García et al.   JOURNAL OF PINEAL RESEARCH

Melatonin modulates microsomal PGE synthase 1 and NF-E2-related factor-2-regulated antioxidant enzyme expression in LPS-induced murine peritoneal macrophages

(2013) M Aparicio-Soto et al.   BRITISH JOURNAL OF PHARMACOLOGY

Melatonin reverses tunicamycin-induced endoplasmic reticulum stress in human hepatocellular carcinoma cells and improves cytotoxic response to doxorubicin by increasing CHOP and decreasing Survivin

(2013) Lulu Fan et al.   JOURNAL OF PINEAL RESEARCH

Melatonin induces transcriptional regulation of Bim by FoxO3a in HepG2 cells

(2012) S Carbajo-Pescador et al.   BRITISH JOURNAL OF CANCER

Melatonin prevents ultraviolet radiation-induced alterations in plasma membrane potential and intracellular pH in human keratinocytes

(2012) Konrad Kleszczyński et al.   JOURNAL OF PINEAL RESEARCH

Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin

(2012) Tobias W. Fischer et al.   JOURNAL OF PINEAL RESEARCH

Endoplasmic reticulum stress induced by hepatitis B virus X protein enhances cyclo-oxygenase 2 expression via activating transcription factor 4

(2011) Hyun Kook Cho et al.   BIOCHEMICAL JOURNAL

Melatonin modulation of intracellular signaling pathways in hepatocarcinoma HepG2 cell line: role of the MT1 receptor

(2011) Sara Carbajo-Pescador et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as a natural ally against oxidative stress: a physicochemical examination

(2011) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Melatonin sensitizes human hepatoma cells to endoplasmic reticulum stress-induced apoptosis

(2011) Lixia Zha et al.   JOURNAL OF PINEAL RESEARCH

Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease

(2010) Giuseppe Paradies et al.   JOURNAL OF PINEAL RESEARCH