Early intraneuronal amyloid triggers neuron-derived inflammatory signaling in APP transgenic rats and human brain
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Title
Early intraneuronal amyloid triggers neuron-derived inflammatory signaling in APP transgenic rats and human brain
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume -, Issue -, Pages 201914593
Publisher
Proceedings of the National Academy of Sciences
Online
2020-03-07
DOI
10.1073/pnas.1914593117
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Note: Only part of the references are listed.- Increases in a Pro-inflammatory Chemokine, MCP-1, Are Related to Decreases in Memory Over Time
- (2019) Brianne M. Bettcher et al. Frontiers in Aging Neuroscience
- Alzheimer disease risk genes: 29 and counting
- (2019) Lars Bertram et al. Nature Reviews Neurology
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- (2019) Angharad R. Morgan et al. Alzheimers & Dementia
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- (2019) Jagan A. Pillai et al. Annals of Clinical and Translational Neurology
- Microglia monitor and protect neuronal function through specialized somatic purinergic junctions
- (2019) Csaba Cserép et al. SCIENCE
- Principles for central nervous system inflammation research: A call for a consortium approach
- (2018) Joseph Rogers Alzheimers & Dementia
- The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade
- (2018) Erika N. Cline et al. JOURNAL OF ALZHEIMERS DISEASE
- Plasma MCP-1 and Cognitive Decline in Patients with Alzheimer’s Disease and Mild Cognitive Impairment: A Two-year Follow-up Study
- (2018) Wei-Ju Lee et al. Scientific Reports
- Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping
- (2018) Giovanni Di Liberto et al. CELL
- Microdose Lithium NP03 Diminishes Pre-Plaque Oxidative Damage and Neuroinflammation in a Rat Model of Alzheimer’s-like Amyloidosis
- (2018) Edward N. Wilson et al. Current Alzheimer Research
- Elevated Plasma MCP-1 Concentration Following Traumatic Brain Injury as a Potential “Predisposition” Factor Associated with an Increased Risk for Subsequent Development of Alzheimer's Disease
- (2018) Lap Ho et al. JOURNAL OF ALZHEIMERS DISEASE
- Innate immune alterations are elicited in microglial cells before plaque deposition in the Alzheimer’s disease mouse model 5xFAD
- (2018) Antonio Boza-Serrano et al. Scientific Reports
- Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia
- (2018) Jack Brelstaff et al. Cell Reports
- The McGill Transgenic Rat Model of Alzheimer's Disease Displays Cognitive and Motor Impairments, Changes in Anxiety and Social Behavior, and Altered Circadian Activity
- (2018) Tomas Petrasek et al. Frontiers in Aging Neuroscience
- Evidence of intraneuronal Aβ accumulation preceding tau pathology in the entorhinal cortex
- (2018) Lindsay A. Welikovitch et al. ACTA NEUROPATHOLOGICA
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- Early and Late CNS Inflammation in Alzheimer’s Disease: Two Extremes of a Continuum?
- (2017) A. Claudio Cuello TRENDS IN PHARMACOLOGICAL SCIENCES
- BACE1 inhibition by microdose lithium formulation NP03 rescues memory loss and early stage amyloid neuropathology
- (2017) E N Wilson et al. Translational Psychiatry
- A Novel Transgenic Rat Model with a Full Alzheimer's-Like Amyloid Pathology Displays Pre-Plaque Intracellular Amyloid-β-Associated Cognitive Impairment
- (2017) Wanda Carolina Leon et al. JOURNAL OF ALZHEIMERS DISEASE
- Soluble pre-fibrillar tau and β-amyloid species emerge in early human Alzheimer’s disease and track disease progression and cognitive decline
- (2016) David J. Koss et al. ACTA NEUROPATHOLOGICA
- Profiling the human hippocampal proteome at all pathologic stages of Alzheimer's disease
- (2016) David C. Hondius et al. Alzheimers & Dementia
- Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology
- (2016) Adrian Olmos-Alonso et al. BRAIN
- Intraneuronal Amyloid Beta Accumulation Disrupts Hippocampal CRTC1-Dependent Gene Expression and Cognitive Function in a Rat Model of Alzheimer Disease
- (2016) Edward N. Wilson et al. CEREBRAL CORTEX
- Early alterations in blood and brain RANTES and MCP-1 expression and the effect of exercise frequency in the 3xTg-AD mouse model of Alzheimer’s disease
- (2016) Morgan Haskins et al. NEUROSCIENCE LETTERS
- Follow-up evaluation of cognitive function in the randomized Alzheimer's Disease Anti-inflammatory Prevention Trial and its Follow-up Study
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- Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis
- (2015) Celeste M. Karch et al. BIOLOGICAL PSYCHIATRY
- Stereological estimation of neuron number and plaque load in the hippocampal region of a transgenic rat model of Alzheimer's disease
- (2015) Ingrid Heggland et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Proteomic analysis of neurons microdissected from formalin-fixed, paraffin-embedded Alzheimer’s disease brain tissue
- (2015) Eleanor S Drummond et al. Scientific Reports
- The Chemokine MIP-1α/CCL3 impairs mouse hippocampal synaptic transmission, plasticity and memory
- (2015) Elodie Marciniak et al. Scientific Reports
- Neuronal driven pre-plaque inflammation in a transgenic rat model of Alzheimer's disease
- (2014) Cecilia E. Hanzel et al. NEUROBIOLOGY OF AGING
- Longitudinal analysis of the behavioral phenotype in a novel transgenic rat model of early stages of Alzheimer's disease
- (2014) Pablo Galeano et al. Frontiers in Behavioral Neuroscience
- Intracellular Aβ pathology and early cognitive impairments in a transgenic rat overexpressing human amyloid precursor protein: a multidimensional study
- (2014) M Florencia Iulita et al. Acta Neuropathologica Communications
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- (2014) Yingjie Qi et al. Acta Neuropathologica Communications
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- (2013) Laura Peferoen et al. IMMUNOLOGY
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- (2013) Rongzhen Zhang et al. JOURNAL OF NEUROIMMUNOLOGY
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- (2013) R. M. Cohen et al. JOURNAL OF NEUROSCIENCE
- A blood-based predictor for neocortical Aβ burden in Alzheimer’s disease: results from the AIBL study
- (2013) S C Burnham et al. MOLECULAR PSYCHIATRY
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- (2011) Helmut Kettenmann et al. PHYSIOLOGICAL REVIEWS
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- (2010) Stephen D. Ginsberg et al. BIOLOGICAL PSYCHIATRY
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- (2008) Winnie S. Liang et al. NEUROBIOLOGY OF AGING
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