Cellular and viral determinants of retroviral nuclear entry

Knockdown of the host cellular protein transportin 3 attenuates prototype foamy virus infection

(2015) Md. Khadem Ali et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

HIV-1 capsid: the multifaceted key player in HIV-1 infection

(2015) Edward M. Campbell et al.   NATURE REVIEWS MICROBIOLOGY

Chromatin organization at the nuclear pore favours HIV replication

(2015) Mickaël Lelek et al.   Nature Communications

The HIV-1 Integrase Mutant R263A/K264A Is 2-fold Defective for TRN-SR2 Binding and Viral Nuclear Import

(2014) Stéphanie De Houwer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microtubule-associated Proteins 1 (MAP1) Promote Human Immunodeficiency Virus Type I (HIV-1) Intracytoplasmic Routing to the Nucleus

(2014) Juliette Fernandez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 Uncoating Is Facilitated by Dynein and Kinesin 1

(2014) Z. Lukic et al.   JOURNAL OF VIROLOGY

Nuclear Localization Signals in Prototype Foamy Viral Integrase for Successive Infection and Replication in Dividing Cells

(2014) Alamgir Hossain et al.   MOLECULES AND CELLS

Structural basis for nuclear import of splicing factors by human Transportin 3

(2014) G. N. Maertens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse mammary tumor virus-based vector transduces non-dividing cells, enters the nucleus via a TNPO3-independent pathway and integrates in a less biased fashion than other retroviruses

(2014) Constantine Konstantoulas et al.   Retrovirology

BI-2 destabilizes HIV-1 cores during infection and Prevents Binding of CPSF6 to the HIV-1 Capsid

(2014) Thomas Fricke et al.   Retrovirology

Gene Therapy Strategies to Exploit TRIM Derived Restriction Factors against HIV-1

(2014) Emma Chan et al.   Viruses-Basel

Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly

(2014) Amanda J. Price et al.   PLoS Pathogens

Nucleocytoplasmic shuttling of HIV-1 integrase is controlled by the viral Rev protein

(2014) Aviad Levin et al.   Nucleus

Transportin 3 and importin α are required for effective nuclear import of HIV-1 integrase in virus-infected cells

(2014) Aviad Levin et al.   Nucleus

The Capsids of HIV-1 and HIV-2 Determine Immune Detection of the Viral cDNA by the Innate Sensor cGAS in Dendritic Cells

(2013) Xavier Lahaye et al.   IMMUNITY

Human Cytosolic Extracts Stabilize the HIV-1 Core

(2013) T. Fricke et al.   JOURNAL OF VIROLOGY

Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay

(2013) Hongzhan Xu et al.   Retrovirology

TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm

(2013) Alberto De Iaco et al.   Retrovirology

Cellular Self-Defense: How Cell-Autonomous Immunity Protects Against Pathogens

(2013) F. Randow et al.   SCIENCE

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication

(2013) Francesca Di Nunzio et al.   VIROLOGY

Viral and Cellular Requirements for the Nuclear Entry of Retroviral Preintegration Nucleoprotein Complexes

(2013) Kenneth Matreyek et al.   Viruses-Basel

Learning from the Messengers: Innate Sensing of Viruses and Cytokine Regulation of Immunity — Clues for Treatments and Vaccines

(2013) Jesper Melchjorsen   Viruses-Basel

The T-Cell Response to HIV

(2013) B. Walker et al.   Cold Spring Harbor Perspectives in Medicine

Nucleoporin NUP153 Phenylalanine-Glycine Motifs Engage a Common Binding Pocket within the HIV-1 Capsid Protein to Mediate Lentiviral Infectivity

(2013) Kenneth A. Matreyek et al.   PLoS Pathogens

An overview of intracellular interactions between immunodeficiency viruses and their hosts

(2012) Paul D. Bieniasz   AIDS

Phosphorylation meets nuclear import: a review

(2012) Jonathan D Nardozzi et al.   Cell Communication and Signaling

Interaction of the HIV-1 Intasome with Transportin 3 Protein (TNPO3 or TRN-SR2)

(2012) Ross Larue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Contribution of Host Nucleoporin 62 in HIV-1 Integrase Chromatin Association and Viral DNA Integration

(2012) Zhujun Ao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 Capsid-Targeting Domain of Cleavage and Polyadenylation Specificity Factor 6

(2012) K. Lee et al.   JOURNAL OF VIROLOGY

TNPO3 Is Required for HIV-1 Replication after Nuclear Import but prior to Integration and Binds the HIV-1 Core

(2012) J. C. Valle-Casuso et al.   JOURNAL OF VIROLOGY

CRM1-Dependent Trafficking of Retroviral Gag Proteins Revisited

(2012) Mariju F. Baluyot et al.   JOURNAL OF VIROLOGY

The Host Proteins Transportin SR2/TNPO3 and Cyclophilin A Exert Opposing Effects on HIV-1 Uncoating

(2012) V. B. Shah et al.   JOURNAL OF VIROLOGY

Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration

(2012) Francesca Di Nunzio et al.   PLoS One

Capturing directed molecular motion in the nuclear pore complex of live cells

(2012) F. Cardarelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cleavage factor Imis a key regulator of 3′ UTR length

(2012) Andreas R. Gruber et al.   RNA Biology

CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication

(2012) Amanda J. Price et al.   PLoS Pathogens

HIV-1 remodels the nuclear pore complex

(2011) Anne Monette et al.   JOURNAL OF CELL BIOLOGY

The Requirement for Nucleoporin NUP153 during Human Immunodeficiency Virus Type 1 Infection Is Determined by the Viral Capsid

(2011) K. A. Matreyek et al.   JOURNAL OF VIROLOGY

Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection

(2011) Candela Iglesias et al.   Retrovirology

Cellular kinases incorporated into HIV-1 particles: passive or active passengers?

(2011) Charline Giroud et al.   Retrovirology

HIV-1 Accessory Protein Vpr: Relevance in the pathogenesis of HIV and potential for therapeutic intervention

(2011) Michael Kogan et al.   Retrovirology

Inhibition of HIV-1 infection by TNPO3 depletion is determined by capsid and detectable after viral cDNA enters the nucleus

(2011) Alberto De Iaco et al.   Retrovirology

Mutations affecting interaction of integrase with TNPO3 do not prevent HIV-1 cDNA nuclear import

(2011) Alexandra Cribier et al.   Retrovirology

The role of unintegrated DNA in HIV infection

(2011) Richard D Sloan et al.   Retrovirology

ADAR1 is a novel multi targeted anti-HIV-1 cellular protein

(2011) Nabanita Biswas et al.   VIROLOGY

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

(2011) Torsten Schaller et al.   PLoS Pathogens

HIV Integration Targeting: A Pathway Involving Transportin-3 and the Nuclear Pore Protein RanBP2

(2011) Karen E. Ocwieja et al.   PLoS Pathogens

How viruses access the nucleus

(2010) Sarah Cohen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Strategies to inhibit viral protein nuclear import: HIV-1 as a target

(2010) Aviad Levin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Flexible Use of Nuclear Import Pathways by HIV-1

(2010) KyeongEun Lee et al.   Cell Host & Microbe

Functional interactions between nucleoporins and chromatin

(2010) Yun Liang et al.   CURRENT OPINION IN CELL BIOLOGY

Lentivirus-associated MAPK/ERK2 phosphorylates EMD and regulates infectivity

(2010) T. N. Bukong et al.   JOURNAL OF GENERAL VIROLOGY

Importin  3 Interacts with HIV-1 Integrase and Contributes to HIV-1 Nuclear Import and Replication

(2010) Z. Ao et al.   JOURNAL OF VIROLOGY

Perturbation of Host Nuclear Membrane Component RanBP2 Impairs the Nuclear Import of Human Immunodeficiency Virus -1 Preintegration Complex (DNA)

(2010) Ruonan Zhang et al.   PLoS One

Revisiting HIV-1 uncoating

(2010) Nathalie Arhel   Retrovirology

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

Nucleoporin 153 Arrests the Nuclear Import of Hepatitis B Virus Capsids in the Nuclear Basket

(2010) André Schmitz et al.   PLoS Pathogens

From experimental setup to bioinformatics: An RNAi screening platform to identify host factors involved in HIV-1 replication

(2009) Kathleen Börner et al.   Biotechnology Journal

The nuclear pore component Nup358 promotes transportin-dependent nuclear import

(2009) S. Hutten et al.   JOURNAL OF CELL SCIENCE

The Requirement for Cellular Transportin 3 (TNPO3 or TRN-SR2) during Infection Maps to Human Immunodeficiency Virus Type 1 Capsid and Not Integrase

(2009) L. Krishnan et al.   JOURNAL OF VIROLOGY

Integrase Interacts with Nucleoporin NUP153 To Mediate the Nuclear Import of Human Immunodeficiency Virus Type 1

(2009) C. L. Woodward et al.   JOURNAL OF VIROLOGY

Target Cell Type-Dependent Modulation of Human Immunodeficiency Virus Type 1 Capsid Disassembly by Cyclophilin A

(2009) Y. Li et al.   JOURNAL OF VIROLOGY

Human host factors required for influenza virus replication

(2009) Renate König et al.   NATURE

Host Cell Factors in HIV Replication: Meta-Analysis of Genome-Wide Studies

(2009) Frederic D. Bushman et al.   PLoS Pathogens

Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication

(2008) Renate König et al.   CELL

Transportin-SR2 Imports HIV into the Nucleus

(2008) Frauke Christ et al.   CURRENT BIOLOGY

Cyclophilin A Levels Dictate Infection Efficiency of Human Immunodeficiency Virus Type 1 Capsid Escape Mutants A92E and G94D

(2008) L. M. J. Ylinen et al.   JOURNAL OF VIROLOGY

Leader-Induced Phosphorylation of Nucleoporins Correlates with Nuclear Trafficking Inhibition by Cardioviruses

(2008) F. W. Porter et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus Replication: Roles of Viral Proteins and Nucleoporins in Capsid-Nucleus Attachment

(2008) A. M. Copeland et al.   JOURNAL OF VIROLOGY

Direct Vpr-Vpr Interaction in Cells monitored by two Photon Fluorescence Correlation Spectroscopy and Fluorescence Lifetime Imaging

(2008) Joelle V Fritz et al.   Retrovirology

Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

(2008) Abraham L. Brass et al.   SCIENCE

Restriction of retroviral replication by APOBEC3G/F and TRIM5α

(2008) Hendrik Huthoff et al.   TRENDS IN MICROBIOLOGY