An overview of intracellular interactions between immunodeficiency viruses and their hosts

HIV reservoirs

(2012) Tae-Wook Chun et al.   AIDS

Evolutionary and Functional Analyses of the Interaction between the Myeloid Restriction Factor SAMHD1 and the Lentiviral Vpx Protein

(2012) Nadine Laguette et al.   Cell Host & Microbe

The Cytoplasmic Domain of the HIV-1 Glycoprotein gp41 Induces NF-κB Activation through TGF-β-Activated Kinase 1

(2012) Thomas S. Postler et al.   Cell Host & Microbe

The Ability of Primate Lentiviruses to Degrade the Monocyte Restriction Factor SAMHD1 Preceded the Birth of the Viral Accessory Protein Vpx

(2012) Efrem S. Lim et al.   Cell Host & Microbe

HIV-1 Capsid-Targeting Domain of Cleavage and Polyadenylation Specificity Factor 6

(2012) K. Lee et al.   JOURNAL OF VIROLOGY

Human Immunodeficiency Virus Type 1 Capsid Mutation N74D Alters Cyclophilin A Dependence and Impairs Macrophage Infection

(2012) Zandrea Ambrose et al.   JOURNAL OF VIROLOGY

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

(2012) Hichem Lahouassa et al.   NATURE IMMUNOLOGY

ESCRT-III Protein Requirements for HIV-1 Budding

(2011) Eiji Morita et al.   Cell Host & Microbe

Compensatory Changes in the Cytoplasmic Tail of gp41 Confer Resistance to Tetherin/BST-2 in a Pathogenic Nef-Deleted SIV

(2011) Ruth Serra-Moreno et al.   Cell Host & Microbe

One Protein to Rule them All: Modulation of Cell Surface Receptors and Molecules by HIV Nef

(2011) Alessia Landi et al.   CURRENT HIV RESEARCH

Aicardi-Goutières Syndrome Gene and HIV-1 Restriction Factor SAMHD1 Is a dGTP-regulated Deoxynucleotide Triphosphohydrolase

(2011) Rebecca D. Powell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Immunodeficiency Virus Type 1 and Related Primate Lentiviruses Engage Clathrin through Gag-Pol or Gag

(2011) S. Popov et al.   JOURNAL OF VIROLOGY

Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation

(2011) Li Zhang et al.   NATURE

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

(2011) Thomas Pertel et al.   NATURE

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

(2011) David C. Goldstone et al.   NATURE

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

(2011) Nadine Laguette et al.   NATURE

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

(2011) Kasia Hrecka et al.   NATURE

Host factors involved in retroviral budding and release

(2011) Juan Martin-Serrano et al.   NATURE REVIEWS MICROBIOLOGY

Antiretroviral restriction factors

(2011) Theodora Hatziioannou et al.   Current Opinion in Virology

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

(2011) Torsten Schaller et al.   PLoS Pathogens

Evolution of a Species-Specific Determinant within Human CRM1 that Regulates the Post-transcriptional Phases of HIV-1 Replication

(2011) Nathan M. Sherer et al.   PLoS Pathogens

Clathrin Facilitates the Morphogenesis of Retrovirus Particles

(2011) Fengwen Zhang et al.   PLoS Pathogens

Flexible Use of Nuclear Import Pathways by HIV-1

(2010) KyeongEun Lee et al.   Cell Host & Microbe

Serine-Threonine Ubiquitination Mediates Downregulation of BST-2/Tetherin and Relief of Restricted Virion Release by HIV-1 Vpu

(2010) A. A. Tokarev et al.   JOURNAL OF VIROLOGY

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

(2010) Nicolas Manel et al.   NATURE

Hexagonal assembly of a restricting TRIM5  protein

(2010) B. K. Ganser-Pornillos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRIM5 Suppresses Cross-Species Transmission of a Primate Immunodeficiency Virus and Selects for Emergence of Resistant Variants in the New Species

(2010) Andrea Kirmaier et al.   PLOS BIOLOGY

Antagonism of Tetherin Restriction of HIV-1 Release by Vpu Involves Binding and Sequestration of the Restriction Factor in a Perinuclear Compartment

(2010) Mathieu Dubé et al.   PLoS Pathogens

TRIM5α Modulates Immunodeficiency Virus Control in Rhesus Monkeys

(2010) So-Yon Lim et al.   PLoS Pathogens

Tetherin Inhibits HIV-1 Release by Directly Tethering Virions to Cells

(2009) David Perez-Caballero et al.   CELL

Nef Proteins from Simian Immunodeficiency Viruses Are Tetherin Antagonists

(2009) Fengwen Zhang et al.   Cell Host & Microbe

Tetherin-Driven Adaptation of Vpu and Nef Function and the Evolution of Pandemic and Nonpandemic HIV-1 Strains

(2009) Daniel Sauter et al.   Cell Host & Microbe

Cellular Restriction Targeting Viral Capsids Perturbs Human Immunodeficiency Virus Type 1 Infection of Nondividing Cells

(2009) M. Yamashita et al.   JOURNAL OF VIROLOGY

The Requirement for Cellular Transportin 3 (TNPO3 or TRN-SR2) during Infection Maps to Human Immunodeficiency Virus Type 1 Capsid and Not Integrase

(2009) L. Krishnan et al.   JOURNAL OF VIROLOGY

Vpu Directs the Degradation of the Human Immunodeficiency Virus Restriction Factor BST-2/Tetherin via a  TrCP-Dependent Mechanism

(2009) J. L. Douglas et al.   JOURNAL OF VIROLOGY

Vpu Antagonizes BST-2–Mediated Restriction of HIV-1 Release via β-TrCP and Endo-Lysosomal Trafficking

(2009) Richard S. Mitchell et al.   PLoS Pathogens

Species-Specific Activity of SIV Nef and HIV-1 Vpu in Overcoming Restriction by Tetherin/BST2

(2009) Bin Jia et al.   PLoS Pathogens

The Interferon-Induced Protein BST-2 Restricts HIV-1 Release and Is Downregulated from the Cell Surface by the Viral Vpu Protein

(2008) Nanette Van Damme et al.   Cell Host & Microbe

HIV-1 Nef Binds PACS-2 to Assemble a Multikinase Cascade That Triggers Major Histocompatibility Complex Class I (MHC-I) Down-regulation

(2008) Katelyn M. Atkins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclophilin A-Dependent Restriction of Human Immunodeficiency Virus Type 1 Capsid Mutants for Infection of Nondividing Cells

(2008) M. Qi et al.   JOURNAL OF VIROLOGY

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE

Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

(2008) Abraham L. Brass et al.   SCIENCE

HIV-1 Nef Targets MHC-I and CD4 for Degradation Via a Final Common β-COP–Dependent Pathway in T Cells

(2008) Malinda R. Schaefer et al.   PLoS Pathogens