Independent role for presynaptic FMRP revealed by anFMR1missense mutation associated with intellectual disability and seizures

A Chromatin-Dependent Role of the Fragile X Mental Retardation Protein FMRP in the DNA Damage Response

(2014) Roman Alpatov et al.   CELL

Fragile X syndrome due to a missense mutation

(2014) Leila K Myrick et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density

(2014) Laurent Ferron et al.   Nature Communications

A Target Cell-Specific Role for Presynaptic Fmr1 in Regulating Glutamate Release onto Neocortical Fast-Spiking Inhibitory Neurons

(2013) A. B. Patel et al.   JOURNAL OF NEUROSCIENCE

FMRP Regulates Neurotransmitter Release and Synaptic Information Transmission by Modulating Action Potential Duration via BK Channels

(2013) Pan-Yue Deng et al.   NEURON

FMRP Regulates Neurotransmitter Release and Synaptic Information Transmission by Modulating Action Potential Duration via BK Channels

(2013) Pan-Yue Deng et al.   NEURON

Systematic mapping of fragile X granules in the mouse brain reveals a potential role for presynaptic FMRP in sensorimotor functions

(2012) Michael R. Akins et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Regulation of Neuronal Excitability by Interaction of Fragile X Mental Retardation Protein with Slack Potassium Channels

(2012) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Predicting the diagnosis of autism spectrum disorder using gene pathway analysis

(2012) E Skafidas et al.   MOLECULAR PSYCHIATRY

Molecular Mechanisms of Fragile X Syndrome: A Twenty-Year Perspective

(2011) Michael R. Santoro et al.   Annual Review of Pathology-Mechanisms of Disease

Targeting BK (big potassium) channels in epilepsy

(2011) Prosper N'Gouemo   EXPERT OPINION ON THERAPEUTIC TARGETS

Fragile X Mental Retardation Protein Regulates Protein Expression and mRNA Translation of the Potassium Channel Kv4.2

(2011) C. Gross et al.   JOURNAL OF NEUROSCIENCE

Bidirectional Regulation of Dendritic Voltage-Gated Potassium Channels by the Fragile X Mental Retardation Protein

(2011) Hye Young Lee et al.   NEURON

Identification of novel FMR1 variants by massively parallel sequencing in developmentally delayed males

(2010) Stephen C. Collins et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Pre-synaptic BK channels selectively control glutamate versus GABA release from cortical and hippocampal nerve terminals

(2010) Maria Martire et al.   JOURNAL OF NEUROCHEMISTRY

Hypersensitivity to mGluR5 and ERK1/2 Leads to Excessive Protein Synthesis in the Hippocampus of a Mouse Model of Fragile X Syndrome

(2010) E. K. Osterweil et al.   JOURNAL OF NEUROSCIENCE

Fragile X Mental Retardation Protein Is Required for Rapid Experience-Dependent Regulation of the Potassium Channel Kv3.1b

(2010) J. G. Strumbos et al.   JOURNAL OF NEUROSCIENCE

A presynaptic role for FMRP during protein synthesis-dependent long-term plasticity in Aplysia

(2010) S. M. Till et al.   LEARNING & MEMORY

Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack

(2010) Maile R Brown et al.   NATURE NEUROSCIENCE

Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome

(2010) A. Suvrathan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ca2+/Calmodulin-dependent Protein Kinase IV Links Group I Metabotropic Glutamate Receptors to Fragile X Mental Retardation Protein in Cingulate Cortex

(2009) Hansen Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The FXG: A Presynaptic Fragile X Granule Expressed in a Subset of Developing Brain Circuits

(2009) S. B. Christie et al.   JOURNAL OF NEUROSCIENCE

Deficit of Kcnma1 mRNA expression in the dentate gyrus of epileptic rats

(2009) Boris Ermolinsky et al.   NEUROREPORT

A Mouse Model of the Human Fragile X Syndrome I304N Mutation

(2009) Julie B. Zang et al.   PLoS Genetics

Down-regulation of BK channel expression in the pilocarpine model of temporal lobe epilepsy

(2008) Luis F. Pacheco Otalora et al.   BRAIN RESEARCH

Temporal requirements of the fragile X mental retardation protein in the regulation of synaptic structure

(2008) C. L. Gatto et al.   DEVELOPMENT

Dysregulation of large-conductance Ca2+-activated K+ channel expression in nonsyndromal mental retardation due to a cereblon p.R419X mutation

(2008) Joseph J. Higgins et al.   NEUROGENETICS

Fragile X Syndrome: Loss of Local mRNA Regulation Alters Synaptic Development and Function

(2008) Gary J. Bassell et al.   NEURON

FMRP Acts as a Key Messenger for Dopamine Modulation in the Forebrain

(2008) Hansen Wang et al.   NEURON