Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure
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Title
Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure
Authors
Keywords
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Journal
Nature Communications
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2015-06-12
DOI
10.1038/ncomms8229
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Related references
Note: Only part of the references are listed.- Guidelines for Translational Research in Heart Failure
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- Long-Term Effects of AAV1/SERCA2a Gene Transfer in Patients With Severe Heart Failure
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- SUMO-1 Gene Transfer Improves Cardiac Function in a Large-Animal Model of Heart Failure
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- Interplay of Posttranslational Modifications in Sp1 Mediates Sp1 Stability during Cell Cycle Progression
- (2011) Yi-Ting Wang et al. JOURNAL OF MOLECULAR BIOLOGY
- SUMO1-dependent modulation of SERCA2a in heart failure
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- A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis
- (2011) J. D. Kessler et al. SCIENCE
- The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma
- (2010) G. W. Xu et al. BLOOD
- Sumoylation and Regulation of Cardiac Gene Expression
- (2010) Jun Wang et al. CIRCULATION RESEARCH
- SUMO—a post-translational modification with therapeutic potential?
- (2010) Chang-Hoon Woo et al. CURRENT OPINION IN PHARMACOLOGY
- New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
- (2010) Jonathan B. Baell et al. JOURNAL OF MEDICINAL CHEMISTRY
- Chronic Heart Failure: Contemporary Diagnosis and Management
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- SERCA2a Gene Transfer Enhances eNOS Expression and Activity in Endothelial Cells
- (2010) Lahouaria Hadri et al. MOLECULAR THERAPY
- Active site remodelling accompanies thioester bond formation in the SUMO E1
- (2010) Shaun K. Olsen et al. NATURE
- Targeted SERCA2a Gene Expression Identifies Molecular Mechanism and Therapeutic Target for Arrhythmogenic Cardiac Alternans
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- Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID Trial), a First-in-Human Phase 1/2 Clinical Trial
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- Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene
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- Sumoylation of Specificity Protein 1 Augments Its Degradation by Changing the Localization and Increasing the Specificity Protein 1 Proteolytic Process
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