Metabolic characterisation of THP-1 macrophage polarisation using LC–MS-based metabolite profiling

Redox-signals and macrophage biology (for the upcoming issue of molecular aspects of medicine on signaling by reactive oxygen species)

(2018) Andreas Weigert et al.   MOLECULAR ASPECTS OF MEDICINE

Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli

(2018) Kevin M. Rattigan et al.   PLoS One

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

(2018) Evanna L. Mills et al.   NATURE

Influence of Tumor Cell Culture Supernatants on Macrophage Functional Polarization: In Vitro Models of Macrophage-tumor Environment Interaction

(2018) Iuliana Caras et al.   TUMORI

Macrophages and bone inflammation

(2017) Qiaoli Gu et al.   Journal of Orthopaedic Translation

Quantitative profiling of glycerophospholipids during mouse and human macrophage differentiation using targeted mass spectrometry

(2017) Cuiping Zhang et al.   Scientific Reports

Image based Machine Learning for identification of macrophage subsets

(2017) Hassan M. Rostam et al.   Scientific Reports

Non-destructive characterisation of mesenchymal stem cell differentiation using LC-MS-based metabolite footprinting

(2016) Amal Surrati et al.   ANALYST

Integrating immunometabolism and macrophage diversity

(2016) Maxim N. Artyomov et al.   SEMINARS IN IMMUNOLOGY

Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes

(2016) Ekta Lachmandas et al.   Nature Microbiology

Phenotypic, Functional, and Plasticity Features of Classical and Alternatively Activated Human Macrophages

(2015) Abdullah A. Tarique et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Lipid signaling in adipose tissue: Connecting inflammation & metabolism

(2015) Mojgan Masoodi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Microglial M1/M2 polarization and metabolic states

(2015) Ruben Orihuela et al.   BRITISH JOURNAL OF PHARMACOLOGY

Metabolic reprogramming in macrophages and dendritic cells in innate immunity

(2015) Beth Kelly et al.   CELL RESEARCH

Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization

(2015) Abhishek K. Jha et al.   IMMUNITY

Alternative Activation of Human Macrophages Is Rescued by Estrogen Treatment In Vitro and Impaired by Menopausal Status

(2015) Alice Toniolo et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

LC–MS-based absolute metabolite quantification: application to metabolic flux measurement in trypanosomes

(2015) Dong-Hyun Kim et al.   Metabolomics

Atherosclerosis – A matter of unresolved inflammation

(2015) Joana Viola et al.   SEMINARS IN IMMUNOLOGY

Control of macrophage metabolism and activation by mTOR and Akt signaling

(2015) Anthony J. Covarrubias et al.   SEMINARS IN IMMUNOLOGY

The histone deacetylase-6 inhibitor tubacin directly inhibits de novo sphingolipid biosynthesis as an off-target effect

(2014) Deanna Siow et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identifying Small Molecules via High Resolution Mass Spectrometry: Communicating Confidence

(2014) Emma L. Schymanski et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Human macrophage polarization in vitro: Maturation and activation methods compared

(2014) Daphne Y.S. Vogel et al.   IMMUNOBIOLOGY

Metabolic Reprogramming of Macrophages

(2014) Alex J. Freemerman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CCL2 Shapes Macrophage Polarization by GM-CSF and M-CSF: Identification of CCL2/CCR2-Dependent Gene Expression Profile

(2014) E. Sierra-Filardi et al.   JOURNAL OF IMMUNOLOGY

Proposed quantitative and alphanumeric metabolite identification metrics

(2014) Lloyd W. Sumner et al.   Metabolomics

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

(2014) Stanley Ching-Cheng Huang et al.   NATURE IMMUNOLOGY

Macrophage Polarization in Obesity and Type 2 Diabetes: Weighing Down Our Understanding of Macrophage Function?

(2014) Michael James Kraakman et al.   Frontiers in Immunology

Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages

(2014) Meera Rath et al.   Frontiers in Immunology

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

(2013) F. O. Martinez et al.   BLOOD

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

IDEOM: an Excel interface for analysis of LC–MS-based metabolomics data

(2012) Darren J. Creek et al.   BIOINFORMATICS

A new metabolomic assay to examine inflammation and redox pathways following LPS challenge

(2012) Jung H Suh et al.   Journal of Inflammation-London

Characterization of polarized THP-1 macrophages and polarizing ability of LPS and food compounds

(2012) Wasaporn Chanput et al.   Food & Function

Synthesis and biological evaluation of some novel 2-phenyl benzimidazole-1-acetamide derivatives as potential anthelmintic agents

(2011) Ramesh Sawant et al.   ACTA PHARMACEUTICA

PeakML/mzMatch: A File Format, Java Library, R Library, and Tool-Chain for Mass Spectrometry Data Analysis

(2011) Richard A. Scheltema et al.   ANALYTICAL CHEMISTRY

Molecular Mechanism for Adiponectin-dependent M2 Macrophage Polarization

(2011) Palash Mandal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-targeted metabolite profiling in activated macrophage secretion

(2011) Masahiro Sugimoto et al.   Metabolomics

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

Metabolite profiles of human immunodeficiency virus infected CD4+ T cells and macrophages using LC–MS/MS analysis

(2011) Joseph A. Hollenbaugh et al.   VIROLOGY

Novel macrophage polarization model: from gene expression to identification of new anti-inflammatory molecules

(2010) Gloria Lopez-Castejón et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Kdo2-Lipid A, a TLR4-specific Agonist, Inducesde NovoSphingolipid Biosynthesis in RAW264.7 Macrophages, Which Is Essential for Induction of Autophagy

(2010) Kacee Sims et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proinflammatory Clearance of Apoptotic Neutrophils Induces an IL-12lowIL-10high Regulatory Phenotype in Macrophages

(2010) A. A. Filardy et al.   JOURNAL OF IMMUNOLOGY

Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

(2009) Andrew M. Smith et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance

(2009) Lata Mukundan et al.   NATURE MEDICINE

Metabolomics Reveals Metabolic Biomarkers of Crohn's Disease

(2009) Janet Jansson et al.   PLoS One

Role of a Serotonin Precursor in Development of Gut Microvilli

(2008) Kazuhiro Nakamura et al.   AMERICAN JOURNAL OF PATHOLOGY

Highly sensitive feature detection for high resolution LC/MS

(2008) Ralf Tautenhahn et al.   BMC BIOINFORMATICS

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark