Monitoring glycation levels of a bispecific monoclonal antibody at subunit level by ultrahigh-resolution MALDI FT-ICR mass spectrometry
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Monitoring glycation levels of a bispecific monoclonal antibody at subunit level by ultrahigh-resolution MALDI FT-ICR mass spectrometry
Authors
Keywords
-
Journal
mAbs
Volume 12, Issue 1, Pages 1682403
Publisher
Informa UK Limited
Online
2019-10-21
DOI
10.1080/19420862.2019.1682403
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Increased throughput and ultra-high mass resolution in DESI FT-ICR MS imaging through new-generation external data acquisition system and advanced data processing approaches
- (2019) Pieter C. Kooijman et al. Scientific Reports
- Top-Down Analysis of Proteins in Low Charge States
- (2019) Aarti Bashyal et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Top or Middle? Up or Down? Toward a Standard Lexicon for Protein Top-Down and Allied Mass Spectrometry Approaches
- (2019) Frederik Lermyte et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Characterization and prediction of positional 4-hydroxyproline and sulfotyrosine, two post-translational modifications that can occur at substantial levels in CHO cells-expressed biotherapeutics
- (2019) Oksana Tyshchuk et al. mAbs
- Best practices and benchmarks for intact protein analysis for top-down mass spectrometry
- (2019) Daniel P. Donnelly et al. NATURE METHODS
- Middle-up analysis of monoclonal antibodies after combined IgdE and IdeS hinge proteolysis: Investigation of free sulfhydryls
- (2018) Valegh Faid et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Quantitative analysis of glycation and its impact on antigen binding
- (2018) Jingjie Mo et al. mAbs
- Bispecific antibodies for cancer therapy: A review
- (2018) Anuradha Krishnamurthy et al. PHARMACOLOGY & THERAPEUTICS
- Heterogeneity assessment of antibody-derived therapeutics at the intact and middle-up level by low-flow sheathless capillary electrophoresis-mass spectrometry
- (2018) Rob Haselberg et al. ANALYTICA CHIMICA ACTA
- Multiplexed Middle-Down Mass Spectrometry Reveals Light and Heavy Chain Connectivity in a Monoclonal Antibody
- (2018) Kristina Srzentic et al. ANALYTICAL CHEMISTRY
- Unknown
- (2018) BIOTECHNOLOGY AND BIOENGINEERING
- 3-Hydroxy-2-Nitrobenzoic Acid as a MALDI Matrix for In-Source Decay and Evaluation of the Isomers
- (2018) Yuko Fukuyama et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Unknown
- (2018) MASS SPECTROMETRY REVIEWS
- Unknown
- (2018) PROTEOMICS
- Unknown
- (2018) PROTEOMICS
- Structural Analysis of Monoclonal Antibodies by Ultrahigh Resolution MALDI In-Source Decay FT-ICR Mass Spectrometry
- (2018) Yuri E.M. van der Burgt et al. ANALYTICAL CHEMISTRY
- Simultaneous Quantification of Protein Expression and Modifications by Top-down Targeted Proteomics: A Case of Sarcomeric Subproteome
- (2018) Ziqing Lin et al. MOLECULAR & CELLULAR PROTEOMICS
- Charge variants characterization of a monoclonal antibody by ion exchange chromatography coupled on-line to native mass spectrometry: Case study after a long-term storage at +5 °C
- (2017) Y. Leblanc et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Glycation of antibodies: Modification, methods and potential effects on biological functions
- (2017) Bingchuan Wei et al. mAbs
- The making of bispecific antibodies
- (2017) Ulrich Brinkmann et al. mAbs
- Rapid and improved characterization of therapeutic antibodies and antibody related products using IdeS digestion and subunit analysis
- (2016) Jonathan Sjögren et al. ANALYST
- N-glycosylation heterogeneity and the influence on structure, function and pharmacokinetics of monoclonal antibodies and Fc fusion proteins
- (2016) Fabian Higel et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Full validation of therapeutic antibody sequences by middle-up mass measurements and middle-down protein sequencing
- (2016) Anja Resemann et al. mAbs
- Comparison of originator and biosimilar therapeutic monoclonal antibodies using comprehensive two-dimensional liquid chromatography coupled with time-of-flight mass spectrometry
- (2016) Matthew Sorensen et al. mAbs
- Accelerated Isotope Fine Structure Calculation Using Pruned Transition Trees
- (2015) Martin Loos et al. ANALYTICAL CHEMISTRY
- A chemical and computational approach to comprehensive glycation characterization on antibodies
- (2015) Ramsey A Saleem et al. mAbs
- Top-down and Middle-down Protein Analysis Reveals that Intact and Clipped Human Histones Differ in Post-translational Modification Patterns
- (2015) Andrey Tvardovskiy et al. MOLECULAR & CELLULAR PROTEOMICS
- Advantages of Extended Bottom-Up Proteomics Using Sap9 for Analysis of Monoclonal Antibodies
- (2014) Kristina Srzentić et al. ANALYTICAL CHEMISTRY
- Autophaser: An Algorithm for Automated Generation of Absorption Mode Spectra for FT-ICR MS
- (2013) David P. A. Kilgour et al. ANALYTICAL CHEMISTRY
- Protein Analysis by Shotgun/Bottom-up Proteomics
- (2013) Yaoyang Zhang et al. CHEMICAL REVIEWS
- Correct primary structure assessment and extensive glyco-profiling of cetuximab by a combination of intact, middle-up, middle-down and bottom-up ESI and MALDI mass spectrometry techniques
- (2013) Daniel Ayoub et al. mAbs
- Making sure PTMs are not lost after translation
- (2013) Vivien Marx NATURE METHODS
- Rapid Identification of Low Level Glycation Sites in Recombinant Antibodies by Isotopic Labeling with 13C6-Reducing Sugars
- (2012) Jennifer Zhang et al. ANALYTICAL CHEMISTRY
- Biosimilar, Biobetter, and Next Generation Antibody Characterization by Mass Spectrometry
- (2012) Alain Beck et al. ANALYTICAL CHEMISTRY
- The impact of glycosylation on monoclonal antibody conformation and stability
- (2012) Kai Zheng et al. mAbs
- Disulfide bond structures of IgG molecules
- (2012) Hongcheng Liu et al. mAbs
- Characterization and Comparison of Disulfide Linkages and Scrambling Patterns in Therapeutic Monoclonal Antibodies: Using LC-MS with Electron Transfer Dissociation
- (2011) Yi Wang et al. ANALYTICAL CHEMISTRY
- Comprehensive Analysis of Protein Modifications by Top-Down Mass Spectrometry
- (2011) Han Zhang et al. Circulation-Cardiovascular Genetics
- Cleavage of IgG1 and IgG3 by gingipain K from Porphyromonas gingivalis may compromise host defense in progressive periodontitis
- (2011) Bjarne Vincents et al. FASEB JOURNAL
- Rates and impact of human antibody glycation in vivo
- (2011) A. M. Goetze et al. GLYCOBIOLOGY
- Characterization of Site-Specific Glycation During Process Development of a Human Therapeutic Monoclonal Antibody
- (2011) Amanda K. Miller et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Mapping intact protein isoforms in discovery mode using top-down proteomics
- (2011) John C. Tran et al. NATURE
- Glycation of monoclonal antibodies impairs their ability to bind antigen
- (2010) D. M. KENNEDY et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Structural and functional characterization of the trifunctional antibody catumaxomab
- (2010) Dirk Chelius et al. mAbs
- Top-down protein characterization facilitated by ion/ion reactions on a quadrupole/time of flight platform
- (2010) Teng-yi Huang et al. PROTEOMICS
- An improved trypsin digestion method minimizes digestion-induced modifications on proteins
- (2009) Da Ren et al. ANALYTICAL BIOCHEMISTRY
- Unveiling a Glycation Hot Spot in a Recombinant Humanized Monoclonal Antibody
- (2008) Boyan Zhang et al. ANALYTICAL CHEMISTRY
- Glycation during storage and administration of monoclonal antibody formulations
- (2008) S FISCHER et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- A study in glycation of a therapeutic recombinant humanized monoclonal antibody: Where it is, how it got there, and how it affects charge-based behavior
- (2007) Cynthia Quan et al. ANALYTICAL BIOCHEMISTRY
- Heterogeneity of Monoclonal Antibodies
- (2007) Hongcheng Liu et al. JOURNAL OF PHARMACEUTICAL SCIENCES
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now