Recent progress in biomedical applications of RGD‐based ligand: From precise cancer theranostics to biomaterial engineering: A systematic review

Targeted co-delivery of protein and drug to a tumor in vivo by sophisticated RGD-modified lipid-calcium carbonate nanoparticles

(2019) Jian Qing Peng et al.   JOURNAL OF CONTROLLED RELEASE

Cyclic cRGDfk peptide and Chlorin e6 functionalized silk fibroin nanoparticles for targeted drug delivery and photodynamic therapy

(2018) Baiping Mao et al.   BIOMATERIALS

Fluorogenic reaction-based prodrug conjugates as targeted cancer theranostics

(2018) Min Hee Lee et al.   CHEMICAL SOCIETY REVIEWS

In vivo tumor gene delivery using novel peptideticles: pH-responsive and ligand targeted core-shell nanoassembly

(2018) Mohsen Alipour et al.   INTERNATIONAL JOURNAL OF CANCER

Integrins as therapeutic targets in the organ-specific metastasis of human malignant melanoma

(2018) Ruixia Huang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

In vivo characterization of four68Ga-labeled multimeric RGD peptides to image αvβ3integrin expression in two human tumor xenograft mouse models

(2018) Daphne Lobeek et al.   JOURNAL OF NUCLEAR MEDICINE

Integrin (?v?3) Targeted RGD Peptide Based Probe for Cancer Optical Imaging

(2016) Zhiguo Liu et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Development of a Targeted anti-HER2 scFv Chimeric Peptide for Gene Delivery into HER2-Positive Breast Cancer Cells

(2016) Roya Cheraghi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

RGD functionalized poly(ε-caprolactone)/poly(m-anthranilic acid) electrospun nanofibers as high-performing scaffolds for bone tissue engineering RGD functionalized PCL/P3ANA nanofibers

(2016) Zeliha Guler et al.   International Journal of Polymeric Materials and Polymeric Biomaterials

Encapsulation of eptifibatide in RGD-modified nanoliposomes improves platelet aggregation inhibitory activity

(2016) Hassan Bardania et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

RGD peptide-conjugated selenium nanoparticles: antiangiogenesis by suppressing VEGF-VEGFR2-ERK/AKT pathway

(2016) Xiaoyan Fu et al.   Nanomedicine-Nanotechnology Biology and Medicine

RGD-modified lipid disks as drug carriers for tumor targeted drug delivery

(2016) Jie Gao et al.   Nanoscale

RGD functionalized poly(ε-caprolactone)/poly(m-anthranilic acid) electrospun nanofibers as high-performing scaffolds for bone tissue engineering RGD functionalized PCL/P3ANA nanofibers

(2016) Zeliha Guler et al.   International Journal of Polymeric Materials and Polymeric Biomaterials

Optimization of RGD-modified Nano-liposomes Encapsulating Eptifibatide

(2016) Hassan Bardania et al.   Iranian Journal of Biotechnology

Photocrosslinkable chitosan hydrogels functionalized with the RGD peptide and phosphoserine to enhance osteogenesis

(2016) Soyon Kim et al.   Journal of Materials Chemistry B

Intraoperative Identification of Liver Cancer Microfoci Using a Targeted Near-Infrared Fluorescent Probe for Imaging-Guided Surgery

(2016) Chaoting Zeng et al.   Scientific Reports

RGD Peptide-Modified Dendrimer-Entrapped Gold Nanoparticles Enable Highly Efficient and Specific Gene Delivery to Stem Cells

(2015) Lingdan Kong et al.   ACS Applied Materials & Interfaces

A Dual-FRET-Based Versatile Prodrug for Real-Time Drug Release Monitoring and In Situ Therapeutic Efficacy Evaluation

(2015) Shi-Ying Li et al.   ADVANCED FUNCTIONAL MATERIALS

RGD-modified pH-sensitive liposomes for docetaxel tumor targeting

(2015) Minglu Chang et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Development of a novel cyclic RGD peptide for multiple targeting approaches of liposomes to tumor region

(2015) Mohamadreza Amin et al.   JOURNAL OF CONTROLLED RELEASE

In Vivo Cancer Dual-Targeting and Dual-Modality Imaging with Functionalized Quantum Dots

(2015) K. Hu et al.   JOURNAL OF NUCLEAR MEDICINE

Molecular magnetic resonance imaging in cancer

(2015) Mohammad Haris et al.   Journal of Translational Medicine

RGD peptide conjugated liposomal drug delivery system for enhance therapeutic efficacy in treating bone metastasis from prostate cancer

(2014) Fangfang Wang et al.   JOURNAL OF CONTROLLED RELEASE

Tumor-Penetrating iRGD Peptide Inhibits Metastasis

(2014) K. N. Sugahara et al.   MOLECULAR CANCER THERAPEUTICS

Molecular basis for the targeted binding of RGD-containing peptide to integrin αVβ3

(2013) Yu-Ping Yu et al.   BIOMATERIALS

Degradable and biocompatible nanoparticles decorated with cyclic RGD peptide for efficient drug delivery to hepatoma cells in vitro

(2013) Pascal Loyer et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Improvement of pharmacokinetic and antitumor activity of PEGylated liposomal doxorubicin by targeting with N-methylated cyclic RGD peptide in mice bearing C-26 colon carcinomas

(2013) Mohamadreza Amin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo

(2012) Hiroshi Maeda et al.   ADVANCED DRUG DELIVERY REVIEWS

Endothelialization and patency of RGD-functionalized vascular grafts in a rabbit carotid artery model

(2012) Wenting Zheng et al.   BIOMATERIALS

RGD-conjugated albumin nanoparticles as a novel delivery vehicle in pancreatic cancer therapy

(2012) Shunrong Ji et al.   CANCER BIOLOGY & THERAPY

Cyclic RGD peptide-modified liposomal drug delivery system: enhanced cellular uptake in vitro and improved pharmacokinetics in rats

(2012) Zhongya Chen et al.   International Journal of Nanomedicine

Direct Fluorescence Monitoring of the Delivery and Cellular Uptake of a Cancer-Targeted RGD Peptide-Appended Naphthalimide Theragnostic Prodrug

(2012) Min Hee Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis

(2012) Fabienne Danhier et al.   MOLECULAR PHARMACEUTICS

Fatty Acid–RGD Peptide Amphiphile Micelles as Potential Paclitaxel Delivery Carriers to αvβ3Integrin Overexpressing Tumors

(2012) Narashima Murthy Javali et al.   PHARMACEUTICAL RESEARCH

Integrin Targeting for Tumor Optical Imaging

(2012) Yunpeng Ye et al.   Theranostics

RGD-Binding Integrins in Prostate Cancer: Expression Patterns and Therapeutic Prospects against Bone Metastasis

(2012) Mark Sutherland et al.   Cancers

RGD-Modified PEG-PAMAM-DOX Conjugate: In Vitro and In Vivo Targeting to Both Tumor Neovascular Endothelial Cells and Tumor Cells

(2011) Saijie Zhu et al.   ADVANCED MATERIALS

Advantages of RGD peptides for directing cell association with biomaterials

(2011) Susan L. Bellis   BIOMATERIALS

Active targeting of RGD-conjugated bioreducible polymer for delivery of oncolytic adenovirus expressing shRNA against IL-8 mRNA

(2011) Jaesung Kim et al.   BIOMATERIALS

Highly stable surface modifications of poly(3-caprolactone) (PCL) films by molecular self-assembly to promote cells adhesion and proliferation

(2011) Zhihong Wang et al.   CHEMICAL COMMUNICATIONS

Impact of polyplex micelles installed with cyclic RGD peptide as ligand on gene delivery to vascular lesions

(2011) H Kagaya et al.   GENE THERAPY

Nanotechnology and Nanotoxicology in Retinopathy

(2011) Dong Hyun Jo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Novel RGD-lipid conjugate-modified liposomes for enhancing siRNA delivery in human retinal pigment epithelial cells

(2011) Cheng-Wei Chen et al.   International Journal of Nanomedicine

In-vivo study of adhesion and bone growth around implanted laser groove/RGD-functionalized Ti-6Al-4V pins in rabbit femurs

(2011) J. Chen et al.   Materials Science & Engineering C-Materials for Biological Applications

Transglutaminase-mediated oligomerization promotes osteoblast adhesive properties of osteopontin and bone sialoprotein

(2011) Jennifer Forsprecher et al.   Cell Adhesion & Migration

The effect of immobilized RGD peptide in alginate scaffolds on cardiac tissue engineering

(2010) Michal Shachar et al.   Acta Biomaterialia

Helicoidal multi-lamellar features of RGD-functionalized silk biomaterials for corneal tissue engineering

(2010) Eun Seok Gil et al.   BIOMATERIALS

Phage Display in Molecular Imaging and Diagnosis of Cancer

(2010) Susan L. Deutscher   CHEMICAL REVIEWS

Targeted Gene Silencing Using RGD-Labeled Chitosan Nanoparticles

(2010) H. D. Han et al.   CLINICAL CANCER RESEARCH

Targeted delivery of RGD-modified liposomes encapsulating both combretastatin A-4 and doxorubicin for tumor therapy: In vitro and in vivo studies

(2010) Yi-fei Zhang et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Sequential treatment of drug-resistant tumors with RGD-modified liposomes containing siRNA or doxorubicin

(2010) Juan Jiang et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Development and characterization of site specific target sensitive liposomes for the delivery of thrombolytic agents

(2010) Bhuvaneshwar Vaidya et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles

(2010) Yelena Vachutinsky et al.   JOURNAL OF CONTROLLED RELEASE

Peptide-mediated targeted drug delivery

(2010) Sumit Majumdar et al.   MEDICINAL RESEARCH REVIEWS

Novel tumor-targeted RGD peptide–camptothecin conjugates: Synthesis and biological evaluation

(2009) Alma Dal Pozzo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Tissue-Penetrating Delivery of Compounds and Nanoparticles into Tumors

(2009) Kazuki N. Sugahara et al.   CANCER CELL

Synthesis and characterization of a high-affinity  v 6-specific ligand for in vitro and in vivo applications

(2009) S. Li et al.   MOLECULAR CANCER THERAPEUTICS

On the mechanisms of biocompatibility

(2008) David F. Williams   BIOMATERIALS

Affinity manipulation of surface-conjugated RGD peptide to modulate binding of liposomes to activated platelets

(2008) Guofeng Huang et al.   BIOMATERIALS

A novel strategy to graft RGD peptide on biomaterials surfaces for endothelization of small-diamater vascular grafts and tissue engineering blood vessel

(2008) Jiehua Li et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Biomaterials in orthopaedics

(2008) M Navarro et al.   Journal of the Royal Society Interface

Adhesion of MC3T3‐E1 cells to bone sialoprotein and bone osteopontin specifically bound to collagen I

(2007) Matthew T. Bernards et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A