Nanotechnology and Nanotoxicology in Retinopathy

Nanotoxicology: An Interdisciplinary Challenge

(2011) Harald F. Krug et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amorphous silica coatings on magnetic nanoparticles enhance stability and reduce toxicity toin vitroBEAS-2B cells

(2011) Ori Baber et al.   INHALATION TOXICOLOGY

Nanoceria extend photoreceptor cell lifespan in tubby mice by modulation of apoptosis/survival signaling pathways

(2011) Li Kong et al.   NEUROBIOLOGY OF DISEASE

Randomized Comparison of Systemic Anti-inflammatory Therapy Versus Fluocinolone Acetonide Implant for Intermediate, Posterior, and Panuveitis: The Multicenter Uveitis Steroid Treatment Trial

(2011) John H. Kempen et al.   OPHTHALMOLOGY

Nanoceria Inhibit the Development and Promote the Regression of Pathologic Retinal Neovascularization in the Vldlr Knockout Mouse

(2011) Xiaohong Zhou et al.   PLoS One

Interaction of Spherical Silica Nanoparticles with Neuronal Cells: Size-Dependent Toxicity and Perturbation of Calcium Homeostasis

(2011) Paolo Ariano et al.   Small

Microglial Response to Gold Nanoparticles

(2010) Eliza Hutter et al.   ACS Nano

Gold nanoparticles inhibit vascular endothelial growth factor-induced angiogenesis and vascular permeability via Src dependent pathway in retinal endothelial cells

(2010) Kalimuthu Kalishwaralal et al.   ANGIOGENESIS

How to overcome retinal neuropathy: The fight against angiogenesisrelated blindness

(2010) Dong Hyun Jo et al.   ARCHIVES OF PHARMACAL RESEARCH

Bioaccumulation and toxicity of gold nanoparticles after repeated administration in mice

(2010) C. Lasagna-Reeves et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The inhibition of retinal neovascularization by gold nanoparticles via suppression of VEGFR-2 activation

(2010) Jin Hyoung Kim et al.   BIOMATERIALS

Gene therapy for ocular diseases

(2010) M. M. Liu et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Drug delivery to the posterior segment of the eye

(2010) Thilini Rasika Thrimawithana et al.   DRUG DISCOVERY TODAY

Nanoparticles Induce Changes of the Electrical Activity of Neuronal Networks on Microelectrode Array Neurochips

(2010) Alexandra Gramowski et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Pharmacotherapy of uveitis

(2010) Frank F Lee et al.   EXPERT OPINION ON PHARMACOTHERAPY

Silver nano — A trove for retinal therapies

(2010) Kalimuthu Kalishwaralal et al.   JOURNAL OF CONTROLLED RELEASE

POD Nanoparticles Expressing GDNF Provide Structural and Functional Rescue of Light-induced Retinal Degeneration in an Adult Mouse

(2010) Sarah P Read et al.   MOLECULAR THERAPY

Historical evolution in the understanding of Stargardt macular dystrophy

(2010) Gerald Allen Fishman   OPHTHALMIC GENETICS

Inhibition of ceramide biosynthesis preserves photoreceptor structure and function in a mouse model of retinitis pigmentosa

(2010) E. Strettoi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Applications of nanoparticles in ophthalmology

(2010) Yolanda Diebold et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Silver nanoparticles inhibit VEGF induced cell proliferation and migration in bovine retinal endothelial cells

(2009) Kalimuthu Kalishwaralal et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Nanoparticle-Mediated Expression of an Angiogenic Inhibitor Ameliorates Ischemia-Induced Retinal Neovascularization and Diabetes-Induced Retinal Vascular Leakage

(2009) K. Park et al.   DIABETES

Silica-Based Nanoparticle Uptake and Cellular Response by Primary Microglia

(2009) Judy Choi et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa

(2009) Xue Cai et al.   FASEB JOURNAL

Intravenous transferrin, RGD peptide and dual-targeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV

(2009) S R Singh et al.   GENE THERAPY

Nanoparticle–integrin antagonist C16Y peptide treatment of choroidal neovascularization in rats

(2009) Hyuncheol Kim et al.   JOURNAL OF CONTROLLED RELEASE

Enlargement of the Foveal Avascular Zone in Diabetic Retinopathy After Adjunctive Intravitreal Bevacizumab (Avastin) With Pars Plana Vitrectomy

(2009) Sung Jun Lee et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Cell Uptake andin VitroToxicity of Magnetic Nanoparticles Suitable for Drug Delivery

(2009) Urs O. Häfeli et al.   MOLECULAR PHARMACEUTICS

Nanosized zinc oxide particles induce neural stem cell apoptosis

(2009) Xiaoyong Deng et al.   NANOTECHNOLOGY

Intravenously administered gold nanoparticles pass through the blood–retinal barrier depending on the particle size, and induce no retinal toxicity

(2009) Jeong Hun Kim et al.   NANOTECHNOLOGY

Copper nanoparticles exert size and concentration dependent toxicity on somatosensory neurons of rat

(2009) Badanavalu M. Prabhu et al.   Nanotoxicology

Expression changes of dopaminergic system-related genes in PC12 cells induced by manganese, silver, or copper nanoparticles

(2009) Jianyong Wang et al.   NEUROTOXICOLOGY

A Partial Structural and Functional Rescue of a Retinitis Pigmentosa Model with Compacted DNA Nanoparticles

(2009) Xue Cai et al.   PLoS One

Ocular Delivery of Compacted DNA-Nanoparticles Does Not Elicit Toxicity in the Mouse Retina

(2009) Xi-Qin Ding et al.   PLoS One

ABSENCE OF HISTOLOGIC RETINAL TOXICITY OF INTRAVITREAL NANOGOLD IN A RABBIT MODEL

(2009) SOPHIE J. BAKRI et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Action potential changes associated with the inhibitory effects on voltage-gated sodium current of hippocampal CA1 neurons by silver nanoparticles

(2009) Zhaowei Liu et al.   TOXICOLOGY

Expression of genes related to oxidative stress in the mouse brain after exposure to silver-25 nanoparticles☆

(2009) M.F. Rahman et al.   TOXICOLOGY LETTERS

Particle size-dependent organ distribution of gold nanoparticles after intravenous administration

(2008) Wim H. De Jong et al.   BIOMATERIALS

Ocular nanoparticle toxicity and transfection of the retina and retinal pigment epithelium

(2008) Tarl W. Prow et al.   Nanomedicine-Nanotechnology Biology and Medicine

Endogenous VEGF Is Required for Visual Function: Evidence for a Survival Role on Müller Cells and Photoreceptors

(2008) Magali Saint-Geniez et al.   PLoS One

Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO2 nanoparticles

(2008) Jiangxue Wang et al.   TOXICOLOGY