A Dual-FRET-Based Versatile Prodrug for Real-Time Drug Release Monitoring and In Situ Therapeutic Efficacy Evaluation

A dual-FRET-based fluorescence probe for the sequential detection of MMP-2 and caspase-3

(2015) Shi-Ying Li et al.   CHEMICAL COMMUNICATIONS

Small conjugate-based theranostic agents: an encouraging approach for cancer therapy

(2015) Rajesh Kumar et al.   CHEMICAL SOCIETY REVIEWS

Enzyme-Specific Doxorubicin Drug Beacon as Drug-Resistant Theranostic Molecular Probes

(2015) Lye Lin Lock et al.   ACS Macro Letters

Prodrug Applications for Targeted Cancer Therapy

(2014) Irene Giang et al.   AAPS Journal

Cancer-Targeted Monodisperse Mesoporous Silica Nanoparticles as Carrier of Ruthenium Polypyridyl Complexes to Enhance Theranostic Effects

(2014) Lizhen He et al.   ADVANCED FUNCTIONAL MATERIALS

MSN-Mediated Sequential Vascular-to-Cell Nuclear-Targeted Drug Delivery for Efficient Tumor Regression

(2014) Limin Pan et al.   ADVANCED MATERIALS

Real-Time In Vivo Quantitative Monitoring of Drug Release by Dual-Mode Magnetic Resonance and Upconverted Luminescence Imaging

(2014) Jianan Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Activatable Theranostic for Targeted Cancer Therapy and Imaging

(2014) Sankarprasad Bhuniya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A pH-responsive prodrug for real-time drug release monitoring and targeted cancer therapy

(2014) Shi-Ying Li et al.   CHEMICAL COMMUNICATIONS

Imaging of doxorubicin release from theranostic macromolecular prodrugs via fluorescence resonance energy transfer

(2014) Harald R. Krüger et al.   JOURNAL OF CONTROLLED RELEASE

Self-assembled peptide nanoparticles as tumor microenvironment activatable probes for tumor targeting and imaging

(2014) Ying Zhao et al.   JOURNAL OF CONTROLLED RELEASE

In Vivo and in Situ Tracking Cancer Chemotherapy by Highly Photostable NIR Fluorescent Theranostic Prodrug

(2014) Xumeng Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeted Theranostic Platinum(IV) Prodrug with a Built-In Aggregation-Induced Emission Light-Up Apoptosis Sensor for Noninvasive Early Evaluation of Its Therapeutic Responses in Situ

(2014) Youyong Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A FRET-Based Dual-Targeting Theranostic Chimeric Peptide for Tumor Therapy and Real-time Apoptosis Imaging

(2014) Kai Han et al.   Advanced Healthcare Materials

Exploiting the Nanoparticle Plasmon Effect: Observing Drug Delivery Dynamics in Single Cells via Raman/Fluorescence Imaging Spectroscopy

(2013) Bin Kang et al.   ACS Nano

Versatile Fluorescence Resonance Energy Transfer-Based Mesoporous Silica Nanoparticles for Real-Time Monitoring of Drug Release

(2013) Jinping Lai et al.   ACS Nano

Therapeutic nanomedicine based on dual-intelligent functionalized gold nanoparticles for cancer imaging and therapy in vivo

(2013) Wei-Hai Chen et al.   BIOMATERIALS

Gemcitabine–Coumarin–Biotin Conjugates: A Target Specific Theranostic Anticancer Prodrug

(2013) Sukhendu Maiti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FITC–quencher based caspase 3-activatable nanoprobes for effectively sensing caspase 3 in vitro and in cells

(2013) Anming Tang et al.   Nanoscale

Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo

(2013) Greg M. Thurber et al.   Nature Communications

Real-Time Monitoring of Cell Apoptosis and Drug Screening Using Fluorescent Light-Up Probe with Aggregation-Induced Emission Characteristics

(2012) Haibin Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Fluorescence Monitoring of the Delivery and Cellular Uptake of a Cancer-Targeted RGD Peptide-Appended Naphthalimide Theragnostic Prodrug

(2012) Min Hee Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The biology of personalized cancer medicine: Facing individual complexities underlying hallmark capabilities

(2012) Michele De Palma et al.   Molecular Oncology

Multicolor, One- and Two-Photon Imaging of Enzymatic Activities in Live Cells with Fluorescently Quenched Activity-Based Probes (qABPs)

(2011) Mingyu Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cell-Specific, Activatable, and Theranostic Prodrug for Dual-Targeted Cancer Imaging and Therapy

(2011) Santimukul Santra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thiol-Ene Click Chemistry

(2010) Charles E. Hoyle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New advances in molecular mechanisms and the prevention of adriamycin toxicity by antioxidant nutrients

(2010) Sergio Granados-Principal et al.   FOOD AND CHEMICAL TOXICOLOGY

A Smart Nanoprobe Based On Fluorescence-Quenching PEGylated Nanogels Containing Gold Nanoparticles for Monitoring the Response to Cancer Therapy

(2009) Motoi Oishi et al.   ADVANCED FUNCTIONAL MATERIALS

Amphiphilic multi-arm-block copolymer conjugated with doxorubicin via pH-sensitive hydrazone bond for tumor-targeted drug delivery

(2009) Mani Prabaharan et al.   BIOMATERIALS

Human Caspases: Activation, Specificity, and Regulation

(2009) Cristina Pop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A route to brightly fluorescent carbon nanotubes for near-infrared imaging in mice

(2009) Kevin Welsher et al.   Nature Nanotechnology

Drug‐Loaded Superparamagnetic Iron Oxide Nanoparticles for Combined Cancer Imaging and Therapy In Vivo

(2008) Mi Kyung Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Global Mapping of the Topography and Magnitude of Proteolytic Events in Apoptosis

(2008) Melissa M. Dix et al.   CELL

Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes

(2008) Yasuteru Urano et al.   NATURE MEDICINE

Prodrugs: design and clinical applications

(2008) Jarkko Rautio et al.   NATURE REVIEWS DRUG DISCOVERY